ABIN1450053

antibody from antibodies-online

Targeting: SEC62 Dtrp1, HTP1, TLOC1

Western blot (Supportive data in Antibodypedia)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

ABIN1450053

Provider

antibodies-online

Product name

anti-Translocation Protein 1 (TLOC1) (C-Term) antibody

Antibody type

Polyclonal

Antigen

18 amino acid synthetic peptide near the carboxy terminus of Human SEC62

Description

Affinity chromatography purified via peptide column

Reactivity

Human, Mouse, Rat

Host

Rabbit

Epitope

C-Term

Isotype

IgG

Vial size

0.1 mg

Concentration

1.0 mg/mL

Storage

Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Silencing of the SEC62 gene inhibits migratory and invasive potential of various tumor cells.

Greiner M, Kreutzer B, Jung V, Grobholz R, Hasenfus A, Stöhr RF, Tornillo L, Dudek J, Stöckle M, Unteregger G, Kamradt J, Wullich B, Zimmermann R
International journal of cancer. Journal international du cancer 2011 May 15;128(10):2284-95

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Mammalian Sec61 is associated with Sec62 and Sec63.

Meyer HA, Grau H, Kraft R, Kostka S, Prehn S, Kalies KU, Hartmann E
The Journal of biological chemistry 2000 May 12;275(19):14550-7

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SEC62 encodes a putative membrane protein required for protein translocation into the yeast endoplasmic reticulum.

Deshaies RJ, Schekman R
The Journal of cell biology 1989 Dec;109(6 Pt 1):2653-64

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Western blot analysis of SEC62 in rat brain tissue lysate with SEC62 antibody at (A) 0.5 and (B) 1 ug/mL.

Immunohistochemistry

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

Immunohistochemistry of SEC62 in mouse brain tissue with SEC62 antibody at 5 ug/mL.