BS8410

antibody from Bioworld Technology, Inc
Targeting: SRI
Provider product page for BS8410
Western blot
Immunohistochemistry

Antibody data

Product number
BS8410 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SRI polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SRI.
Description
Sorcin is a highly conserved protein, with 95% homology between hamster and human sorcin sequences. Sorcin has four putative Ca-binding domains, two of which exhibit strong homology to calmodulin ¡ùEF hand¡ì motifs. Calcium binding directly to sorcin has been demonstrated by in vitro assays. Sorcin is closely related to members of calpain and sarcoplasmic Ca2+-binding protein subfamilies. Sorcin undergoes calcium-dependent translocation from the cytosol to cellular membranes. Sorcin binds to and modulates ryanodine receptors and is widely distributed including heart and brain tissues. At the subcellular level, sorcin localizes to T-tubule junctions of cardiac sarcoplasmic reticulum.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SRI protein structure - BS8410 shown in red.