Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 20201-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20201-1-AP, RRID:AB_10665556
- Product name
- STEAP2-Specific antibody
- Antibody type
- Polyclonal
- Description
- STEAP2-Specific antibody (Cat. #20201-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references STEAP2 promotes osteosarcoma progression by inducing epithelial-mesenchymal transition via the PI3K/AKT/mTOR signaling pathway and is regulated by EFEMP2.
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
Membrane cholesterol modulates STEAP2 conformation during dynamic intracellular trafficking processes leading to broad subcellular distribution.
Zhang D, Liu H, Wang W, Xu G, Yin C, Wang S
Cancer biology & therapy 2022 Dec 31;23(1):1-16
Cancer biology & therapy 2022 Dec 31;23(1):1-16
METTL3-mediated m6A modification of STEAP2 mRNA inhibits papillary thyroid cancer progress by blocking the Hedgehog signaling pathway and epithelial-to-mesenchymal transition.
Zhu Y, Peng X, Zhou Q, Tan L, Zhang C, Lin S, Long M
Cell death & disease 2022 Apr 18;13(4):358
Cell death & disease 2022 Apr 18;13(4):358
Membrane cholesterol modulates STEAP2 conformation during dynamic intracellular trafficking processes leading to broad subcellular distribution.
Hasegawa H, Li C, Alba BM, Penny DM, Xia Z, Dayao MR, Li P, Zhang J, Zhou J, Lim D, Murawsky CM, Lim AC
Experimental cell research 2018 Sep 15;370(2):208-226
Experimental cell research 2018 Sep 15;370(2):208-226
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 20201-1-AP(STEAP2-Specific antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 20201-1-AP(STEAP2-Specific antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The STEAP2-Specific antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human STEAP2-Specific. This antibody recognizes human,mouse,rat antigen. The STEAP2-Specific antibody has been validated for the following applications: ELISA, WB, IHC analysis.