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- Antigen structure
- References [12]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 11981-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11981-1-AP, RRID:AB_2204353
- Product name
- TMED2 antibody
- Antibody type
- Polyclonal
- Description
- TMED2 antibody (Cat. #11981-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Promotion of hepatocellular carcinoma by small nuclear ribonucleoprotein polypeptide F through upregulation of transmembrane P24 trafficking protein 2 and triggering of the cGAS-STING pathway.
TMEDs mediate versatile cargo transport in vesicle-dependent unconventional secretion.
Study of the role of transmembrane emp24 domain-containing protein 2 in oral squamous cell carcinoma.
TMED9 coordinates the clearance of misfolded GPI-anchored proteins out of the ER and into the Golgi.
Coronavirus envelope protein activates TMED10-mediated unconventional secretion of inflammatory factors.
TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport.
TMED2 Induces Cisplatin Resistance in Breast Cancer via Targeting the KEAP1-Nrf2 Pathway.
A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.
Screening of the novel immune-suppressive biomarkers of TMED family and whether knockdown of TMED2/3/4/9 inhibits cell migration and invasion in breast cancer.
TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike.
ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier.
The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.
Xie X, Pu L, Zeng J, Xu M, Yin X, Liu H, Yang J, Cao J, Song H
International journal of biological macromolecules 2026 Mar;352:151166
International journal of biological macromolecules 2026 Mar;352:151166
TMEDs mediate versatile cargo transport in vesicle-dependent unconventional secretion.
Zheng J, Wang H, Sun Y, Chang P, Deng X, Zhang L, Zhu L, Zhu K, Peng D, Deng H, Zhang M, Ge L
The Journal of cell biology 2026 Jan 5;225(1)
The Journal of cell biology 2026 Jan 5;225(1)
Study of the role of transmembrane emp24 domain-containing protein 2 in oral squamous cell carcinoma.
Zhao-Wei R, Xue-Feng J, Gao-Tian X, Jin-Ling C, Jun LI, Shu-Ying LV
Journal of applied oral science : revista FOB 2025;33:e20240305
Journal of applied oral science : revista FOB 2025;33:e20240305
TMED9 coordinates the clearance of misfolded GPI-anchored proteins out of the ER and into the Golgi.
Ronzier E, Satpute-Krishnan P
PLoS biology 2025 Apr;23(4):e3003084
PLoS biology 2025 Apr;23(4):e3003084
Coronavirus envelope protein activates TMED10-mediated unconventional secretion of inflammatory factors.
Liu L, Zhang L, Hao X, Wang Y, Zhang X, Ge L, Wang P, Tian B, Zhang M
Nature communications 2024 Oct 8;15(1):8708
Nature communications 2024 Oct 8;15(1):8708
TMED2 promotes glioma tumorigenesis by being involved in EGFR recycling transport.
Sun C, Zhang Y, Wang Z, Chen J, Zhang J, Gu Y
International journal of biological macromolecules 2024 Mar;262(Pt 2):130055
International journal of biological macromolecules 2024 Mar;262(Pt 2):130055
TMED2 Induces Cisplatin Resistance in Breast Cancer via Targeting the KEAP1-Nrf2 Pathway.
Liang C, Zhang HY, Wang YQ, Yang LA, Du YS, Luo Y, Zhang TC, Xu Y
Current medical science 2023 Oct;43(5):1023-1032
Current medical science 2023 Oct;43(5):1023-1032
A new type of ERGIC-ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis.
Li S, Yan R, Xu J, Zhao S, Ma X, Sun Q, Zhang M, Li Y, Liu JG, Chen L, Li S, Xu K, Ge L
Cell research 2022 Feb;32(2):119-138
Cell research 2022 Feb;32(2):119-138
Screening of the novel immune-suppressive biomarkers of TMED family and whether knockdown of TMED2/3/4/9 inhibits cell migration and invasion in breast cancer.
Fang Z, Song YX, Wo GQ, Zhou HL, Li L, Yang SY, Chen X, Zhang J, Tang JH
Annals of translational medicine 2022 Dec;10(23):1280
Annals of translational medicine 2022 Dec;10(23):1280
TMED3 Complex Mediates ER Stress-Associated Secretion of CFTR, Pendrin, and SARS-CoV-2 Spike.
Park H, Seo SK, Sim JR, Hwang SJ, Kim YJ, Shin DH, Jang DG, Noh SH, Park PG, Ko SH, Shin MH, Choi JY, Ito Y, Kang CM, Lee JM, Lee MG
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105320
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2022 Aug;9(24):e2105320
ACBD3 modulates KDEL receptor interaction with PKA for its trafficking via tubulovesicular carrier.
Yue X, Qian Y, Zhu L, Gim B, Bao M, Jia J, Jing S, Wang Y, Tan C, Bottanelli F, Ziltener P, Choi S, Hao P, Lee I
BMC biology 2021 Sep 7;19(1):194
BMC biology 2021 Sep 7;19(1):194
The circular RNA CDR1as regulate cell proliferation via TMED2 and TMED10.
Yang X, Li S, Wu Y, Ge F, Chen Y, Xiong Q
BMC cancer 2020 Apr 15;20(1):312
BMC cancer 2020 Apr 15;20(1):312
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse pancreas tissue were subjected to SDS PAGE followed by western blot with 11981-1-AP(TMED2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TMED2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TMED2. This antibody recognizes human, mouse antigen. The TMED2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
