Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B10618 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Human MARCH2 monoclonal antibody, clone 8G4
- Antibody type
- Monoclonal
- Description
- MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]
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