BS8442

antibody from Bioworld Technology, Inc
Targeting: WWP2 AIP2
Provider product page for BS8442
Western blot
Immunohistochemistry

Antibody data

Product number
BS8442 - Provider product page
Provider
Bioworld Technology, Inc
Product name
WWP2 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human WWP2.
Description
Atrophin interacting proteins (AIP)s bind to atrophin-1 in the vicinity of the polyglutamine tract. The WW domain consists of 35-40 amino acids and is characterized by four well conserved aromatic residues, two of which are tryptophan. All five AIPs contain multiple WW domains and can be divided into two distinct classes. AIP1 and AIP3 (WWP3) are MAGUK-like multidomain proteins containing a guanylate kinase-like region, two WW domains and multiple PDZ domains. AIP2 (WWP2), AIP4 (itchy) and AIP5 (WWP1) are highly homologous, each having four WW domains and a HECT domain characteristic of ubiquitin ligases. These interactors are similar to isolated Huntingtin-interacting proteins, suggesting commonality of function between two families of proteins responsible for similar diseases.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
WWP2 protein structure - BS8442 shown in red.