11795-1-AP

antibody from Proteintech Group

Targeting: TPD52L2 D54, hD54, TPD54

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunoprecipitation (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

11795-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#11795-1-AP, RRID:AB_2207431

Product name

TPD52L2 antibody

Antibody type

Polyclonal

Description

KD/KO validated TPD52L2 antibody (Cat. #11795-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Investigation of Transcript Variant 6 of TPD52L2 as a Prognostic and Predictive Biomarker in Basal-Like MDA-MB-231 and MDA-MB-453 Cell Lines for Breast Cancer.

Zhang X, O'Brien D, Zhang X
Oxidative medicine and cellular longevity 2022;2022:7078787

---

Tumor protein D54 binds intracellular nanovesicles via an extended amphipathic region.

Reynaud A, Magdeleine M, Patel A, Gay AS, Debayle D, Abelanet S, Antonny B
The Journal of biological chemistry 2022 Jul;298(7):102136

---

Tumor protein D52 is upregulated in oral squamous carcinoma cells under hypoxia in a hypoxia-inducible-factor-independent manner and is involved in cell death resistance.

Abe Y, Mukudai Y, Kurihara M, Houri A, Chikuda J, Yaso A, Kato K, Shimane T, Shirota T
Cell & bioscience 2021 Jul 3;11(1):122

---

Silencing of TPD52 inhibits proliferation, migration, invasion but induces apoptosis of pancreatic cancer cells by deactivating Akt pathway.

Wang Z, Li Y, Fan L, Zhao Q, Tan B, Liu R, Li F
Neoplasma 2020 Mar;67(2):277-285

---

TPD52L2 impacts proliferation, invasiveness and apoptosis of glioblastoma cells via modulation of wnt/β-catenin/snail signaling.

Qiang Z, Jun-Jie L, Hai W, Hong L, Bing-Xi L, Lei C, Wei X, Ya-Wei L, Huang A, Song-Tao Q, Yun-Tao L
Carcinogenesis 2018 Feb 9;39(2):214-224

---

Tumor Proteins D52 and D54 Have Opposite Effects on the Terminal Differentiation of Chondrocytes.

Ito C, Mukudai Y, Itose M, Kato K, Motohashi H, Shimane T, Kondo S, Shirota T
BioMed research international 2017;2017:6014278

---

Opposite effects of tumor protein D (TPD) 52 and TPD54 on oral squamous cell carcinoma cells.

Kato K, Mukudai Y, Motohashi H, Ito C, Kamoshida S, Shimane T, Kondo S, Shirota T
International journal of oncology 2017 May;50(5):1634-1646

---

Increased expression of tumor protein D54 is associated with clinical progression and poor prognosis in patients with prostate cancer.

Ren L, Chen J, Zhang X
Oncology letters 2017 Dec;14(6):7739-7744

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HEK-293 cells were subjected to SDS PAGE followed by western blot with 11795-1-AP(TPD52L2 antibody) at dilution of 1:800

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of HepG2 cells, using TPD52L2 antibody 11795-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line

Immunoprecipitation

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

IP Result of anti-TPD52L2 (IP:11795-1-AP, 3ug; Detection:11795-1-AP 1:800) with HEK-293 cells lysate 2400ug.

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human breast cancer using 11795-1-AP(TPD52L2 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue