DCABH-4269

antibody from Creative Diagnostics

Targeting: CDC42EP1 Borg5, CEP1, MSE55

Western blot (Recommended by provider)

Antibody Data

Product number

DCABH-4269

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-4269, RRID:AB_2478056

Product name

Rabbit Anti-Human CDC42EP1 monoclonal antibody, clone TE19-65

Antibody type

Monoclonal

Description

MSE55 also known as Borg5 or binder of Rho GTPases 5 is a Cdc42 effector protein that induces long cellular extensions in fibroblasts. MSE55 also increases and mediates actin cytoskeleton reorganization at the plasma membrane. MSE55 is a nonkinase CRIB (Cdc42/Rac interactive-binding) domain-containing molecule. An intact CRIB domain is required for the GTP-dependent binding of MSE55 to Cdc42. MSE55 is expressed in a tissue-specific manner in endothelial and bone marrow stromal cells. MSE55 may have a functional role in hematopoiesis or as a negative regulator of Rho GTPase signaling.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

TE19-65

Vial size

100 _l

Storage

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.