Antibody data

Product number
Ab095317 - Provider product page
Provider
Aladdin Scientific
Product name
CD79a Antibody
Antibody type
Polyclonal
Description
Rabbit anti Human CD79a Antibody, Polyclonal, could be used for WB, IHC, Flow and so on.ApplicationWB: 0.5-2 µg/mLIHC: 5-20 µg/mLFlow: 20_g/mLProtein FunctionRequired in cooperation with CD79B for initiation of the signal transduction cascade activated by binding of antigen to the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Also required for BCR surface expression and for efficient differentiation of pro- and pre-B-cells. Stimulates SYK autophosphorylation and activation. Binds to BLNK, bringing BLNK into proximity with SYK and allowing SYK to phosphorylate BLNK. Also interacts with and increases activity of some Src-family tyrosine kinases. Represses BCR signaling during development of immature B cells.
Reactivity
Human
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
AA 36-219
Vial size
100_l,10_l,1ml,20_l,50_l
Concentration
Lot by Lot
Storage
Store at 4_ short term (1-2 weeks). Store at -20_ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
CD79A protein structure - Ab095317 shown in red.