22490-1-AP
antibody from Proteintech Group
Targeting: CEP290
3H11Ag, BBS14, CT87, FLJ13615, JBTS5, KIAA0373, LCA10, MKS4, NPHP6, POC3, rd16, SLSN6
Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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Validation data
Reference
Comment
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- Product number
- 22490-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22490-1-AP, RRID:AB_10973679
- Product name
- CEP290 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CEP290 antibody (Cat. #22490-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy.
Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors.
Centriolar satellites are required for efficient ciliogenesis and ciliary content regulation.
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration.
The small GTPase RSG1 controls a final step in primary cilia initiation.
DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.
Martello A, Lauriola A, Mellis D, Parish E, Dawson JC, Imrie L, Vidmar M, Gammoh N, Mitić T, Brittan M, Mills NL, Carragher NO, D'Arca D, Caporali A
EMBO reports 2020 Jul 3;21(7):e48192
EMBO reports 2020 Jul 3;21(7):e48192
Centrosomal and ciliary targeting of CCDC66 requires cooperative action of centriolar satellites, microtubules and molecular motors.
Conkar D, Bayraktar H, Firat-Karalar EN
Scientific reports 2019 Oct 3;9(1):14250
Scientific reports 2019 Oct 3;9(1):14250
Centriolar satellites are required for efficient ciliogenesis and ciliary content regulation.
Odabasi E, Gul S, Kavakli IH, Firat-Karalar EN
EMBO reports 2019 Jun;20(6)
EMBO reports 2019 Jun;20(6)
The myosin-tail homology domain of centrosomal protein 290 is essential for protein confinement between the inner and outer segments in photoreceptors.
Datta P, Hendrickson B, Brendalen S, Ruffcorn A, Seo S
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
The Journal of biological chemistry 2019 Dec 13;294(50):19119-19136
A CEP290 C-Terminal Domain Complements the Mutant CEP290 of Rd16 Mice In Trans and Rescues Retinal Degeneration.
Mookherjee S, Chen HY, Isgrig K, Yu W, Hiriyanna S, Levron R, Li T, Colosi P, Chien W, Swaroop A, Wu Z
Cell reports 2018 Oct 16;25(3):611-623.e6
Cell reports 2018 Oct 16;25(3):611-623.e6
The small GTPase RSG1 controls a final step in primary cilia initiation.
Agbu SO, Liang Y, Liu A, Anderson KV
The Journal of cell biology 2018 Jan 2;217(1):413-427
The Journal of cell biology 2018 Jan 2;217(1):413-427
DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle.
Zhang B, Wang G, Xu X, Yang S, Zhuang T, Wang G, Ren H, Cheng SY, Jiang Q, Zhang C
The Journal of biological chemistry 2017 Jan 27;292(4):1351-1360
The Journal of biological chemistry 2017 Jan 27;292(4):1351-1360
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 22490-1-AP(CEP290 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP result of anti-CEP290(22490-1-AP for IP and Detection).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human placenta using 22490-1-AP(CEP290 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue