Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS6685 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- ORM1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human ORM1.
- Description
- Alpha 1 acid glycoprotein (AGP) is an acute phase plasma protein synthesized by the liver. It functions to regulate the interaction between blood cells and endothelial cells, and together with haptoglobin and C reactive protein, it also mediates the extravasation of cells during infection and inflammation. Expression of AGP is induced by acute-phase stimulatory agents such as bacterial lipopolysaccharides. AGP has a high affinity, low capacity binding for basic drugs at physiological pH. In human plasma, AGP is found at 0.5-1.4 mg/ml. These levels are elevated during acute inflammation; therefore AGP protein levels can be used to diagnose inflammatory conditions. Multiple AGP genes exist, including AGP 1, AGP 2, AGP 3 and AGP 8. AGP 1 and AGP 2 contain five and six potential N-glycosylation sites, respectively. Abnormal expression of the APG 1 gene is linked to sarcoidosis and other immunogenetic diseases, while mutations in the APG 2 gene are associated with different types of carcinomas.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
- Main image
- Experimental details
- Western blot analysis of ORM1 polyclonal antibody