Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 16439-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ORM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ORM1 antibody (Cat. #16439-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ORM2 protects against acute pancreatitis by inhibiting premature activation of pancreatic enzymes.
Prognostic analysis and identification of M7G immune-related genes in lung squamous cell carcinoma.
Orosomucoid 1 Participates in Alveolar Hypercoagulation and Fibrinolytic Inhibition Involving NF-κB Signaling Pathway in LPS-Induced ARDS.
Multi-omics analysis reveals metabolic disruptions in cardiac tissues of aging nonhuman primates with spontaneous type 2 diabetes.
Jellyfish stings-induced cardiac failure was ameliorated through AAG-mediated glycogen-driven ATP production.
Orosomucoid 1 interacts with S100A12 and activates ERK signalling to expedite the advancement of bladder cancer.
Abnormal Vessels Potentially Accelerate Glioblastoma Proliferation by Inducing the Protumor Activation of Macrophages.
Therapeutic Target Discovery for Multiple Myeloma: Identifying Druggable Genes via Mendelian Randomization.
Integrative omics analysis identifies biomarkers of septic cardiomyopathy.
Contribution of the α(1)-Acid Glycoprotein in Drug Pharmacokinetics: The Usefulness of α(1)-Acid Glycoprotein-Knockout Mice.
Proteome characterization of liver-kidney comorbidity after microbial sepsis.
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis.
Urine Proteome in Distinguishing Hepatic Steatosis in Patients with Metabolic-Associated Fatty Liver Disease.
Thapsigargin suppresses alpha 1-acid glycoprotein secretion independently of N-glycosylation and ER stress.
Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9.
An acute phase protein α(1)-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action.
α(1)-Acid Glycoprotein Attenuates Adriamycin-Induced Nephropathy via CD163 Expressing Macrophage Induction.
FXR-Gankyrin axis is involved in development of pediatric liver cancer.
The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation.
Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.
Huang B, Si Z, Tan X, Wang Y, Gao J, Zhang Y, Yang X, Liu X, Li Z, Hu L, Wang P
Translational gastroenterology and hepatology 2026;11:10
Translational gastroenterology and hepatology 2026;11:10
Prognostic analysis and identification of M7G immune-related genes in lung squamous cell carcinoma.
Wenhui L, Nan W, Jiayi H, Ye X, Chunyu H, Zhongzhou L, Hongtao L, Hui T
Frontiers in immunology 2025;16:1515838
Frontiers in immunology 2025;16:1515838
Orosomucoid 1 Participates in Alveolar Hypercoagulation and Fibrinolytic Inhibition Involving NF-κB Signaling Pathway in LPS-Induced ARDS.
Chen X, Liu Y, Mu S, Chen T, Yuan J, Xiao C, Dong Q, Li Q, Wang Y, Chen Q, Li S, Li W, Shen F
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 15;39(21):e71147
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2025 Nov 15;39(21):e71147
Multi-omics analysis reveals metabolic disruptions in cardiac tissues of aging nonhuman primates with spontaneous type 2 diabetes.
Liu Y, Yu J, Hu H, Pu S, Wu H, Ma Y, Yang W, Fang C, Sun F, Wang H
Aging 2025 Jun 2;17(6):1386-1404
Aging 2025 Jun 2;17(6):1386-1404
Jellyfish stings-induced cardiac failure was ameliorated through AAG-mediated glycogen-driven ATP production.
Qin Z, Chen J, Liu F, Li B, Zhang C, Wang X, Liu L, Wang M, Wang T, Wang S, Yu F, Wang S, Yang J
Exploration (Beijing, China) 2025 Feb;5(1):20230089
Exploration (Beijing, China) 2025 Feb;5(1):20230089
Orosomucoid 1 interacts with S100A12 and activates ERK signalling to expedite the advancement of bladder cancer.
Liu Z, Pu X
Cell adhesion & migration 2025 Dec;19(1):1-11
Cell adhesion & migration 2025 Dec;19(1):1-11
Abnormal Vessels Potentially Accelerate Glioblastoma Proliferation by Inducing the Protumor Activation of Macrophages.
Matsuzaki H, Kai K, Komohara Y, Yano H, Pan C, Fujiwara Y, Yamada R, Iwauchi A, Fukasawa N, Tanaka T, Shimoda M, Watanabe H, Maruyama T, Takeo T, Mikami Y, Mukasa A
Cancer science 2025 Apr;116(4):897-909
Cancer science 2025 Apr;116(4):897-909
Therapeutic Target Discovery for Multiple Myeloma: Identifying Druggable Genes via Mendelian Randomization.
Jiang S, Fan F, Li Q, Zuo L, Xu A, Sun C
Biomedicines 2025 Apr 5;13(4)
Biomedicines 2025 Apr 5;13(4)
Integrative omics analysis identifies biomarkers of septic cardiomyopathy.
Cai K, Luo Y, Chen H, Dong Y, Su Y, Lin C, Cai C, Shi Y, Lin S, Lian G, Lin Z, Feng S
PloS one 2024;19(11):e0310412
PloS one 2024;19(11):e0310412
Contribution of the α(1)-Acid Glycoprotein in Drug Pharmacokinetics: The Usefulness of α(1)-Acid Glycoprotein-Knockout Mice.
Nakamura Y, Watanabe H, Imafuku T, Fujita I, Ganaha Y, Takeo T, Nakagata N, Maeda H, Maruyama T
Molecular pharmaceutics 2024 Jul 1;21(7):3144-3150
Molecular pharmaceutics 2024 Jul 1;21(7):3144-3150
Proteome characterization of liver-kidney comorbidity after microbial sepsis.
Gui Y, Yu Y, Wang W, Wang Y, Lu H, Mozdzierz S, Eskander K, Lin YH, Li H, Tian XJ, Liu S, Zhou D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23597
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23597
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
Yue L, Xu X, Dai S, Xu F, Zhao W, Gu J, Dai X, Qian X
Scientific reports 2023 Aug 28;13(1):14092
Scientific reports 2023 Aug 28;13(1):14092
Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis.
Zhou B, Luo Y, Ji N, Hu C, Lu Y
Nature metabolism 2022 Sep;4(9):1185-1201
Nature metabolism 2022 Sep;4(9):1185-1201
Urine Proteome in Distinguishing Hepatic Steatosis in Patients with Metabolic-Associated Fatty Liver Disease.
Liu CH, Zheng S, Wang S, Wu D, Jiang W, Zeng Q, Wei Y, Zhang Y, Tang H
Diagnostics (Basel, Switzerland) 2022 Jun 7;12(6)
Diagnostics (Basel, Switzerland) 2022 Jun 7;12(6)
Thapsigargin suppresses alpha 1-acid glycoprotein secretion independently of N-glycosylation and ER stress.
Goto N, Shibutani S, Miura N, Watanabe R, Iwata H
Biochemical and biophysical research communications 2021 May 7;552:30-36
Biochemical and biophysical research communications 2021 May 7;552:30-36
Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9.
Qiong L, Yin J
Bioengineered 2021 Dec;12(1):8822-8832
Bioengineered 2021 Dec;12(1):8822-8832
An acute phase protein α(1)-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action.
Watanabe H, Fujimura R, Hiramoto Y, Murata R, Nishida K, Bi J, Imafuku T, Komori H, Maeda H, Mukunoki A, Takeo T, Nakagata N, Tanaka M, Matsushita K, Fukagawa M, Maruyama T
Scientific reports 2021 Apr 12;11(1):7953
Scientific reports 2021 Apr 12;11(1):7953
α(1)-Acid Glycoprotein Attenuates Adriamycin-Induced Nephropathy via CD163 Expressing Macrophage Induction.
Fujimura R, Watanabe H, Nishida K, Fujiwara Y, Koga T, Bi J, Imafuku T, Kobayashi K, Komori H, Miyahisa M, Maeda H, Tanaka M, Matsushita K, Wada T, Fukagawa M, Maruyama T
Kidney360 2020 May 28;1(5):343-353
Kidney360 2020 May 28;1(5):343-353
FXR-Gankyrin axis is involved in development of pediatric liver cancer.
Valanejad L, Lewis K, Wright M, Jiang Y, D'Souza A, Karns R, Sheridan R, Gupta A, Bove K, Witte D, Geller J, Tiao G, Nelson DL, Timchenko L, Timchenko N
Carcinogenesis 2017 Jul 1;38(7):738-747
Carcinogenesis 2017 Jul 1;38(7):738-747
The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation.
Mobin MB, Gerstberger S, Teupser D, Campana B, Charisse K, Heim MH, Manoharan M, Tuschl T, Stoffel M
Nature communications 2016 Sep 26;7:12848
Nature communications 2016 Sep 26;7:12848
Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.
Jin Y, Wang J, Ye X, Su Y, Yu G, Yang Q, Liu W, Yu W, Cai J, Chen X, Liang Y, Chen Y, Wong BH, Fu X, Sun H
British journal of cancer 2016 Mar 1;114(5):532-44
British journal of cancer 2016 Mar 1;114(5):532-44
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 16439-1-AP(ORM1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-ORM1 (IP:16439-1-AP, 3ug; Detection:16439-1-AP 1:300) with human plasma tissue lysate 100ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ORM1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ORM1. This antibody recognizes human, mouse antigen. The ORM1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
