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Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [1]
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- Product number
- 16439-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ORM1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ORM1 antibody (Cat. #16439-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Proteome characterization of liver-kidney comorbidity after microbial sepsis.
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis.
Urine Proteome in Distinguishing Hepatic Steatosis in Patients with Metabolic-Associated Fatty Liver Disease.
Thapsigargin suppresses alpha 1-acid glycoprotein secretion independently of N-glycosylation and ER stress.
Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9.
An acute phase protein α(1)-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action.
α(1)-Acid Glycoprotein Attenuates Adriamycin-Induced Nephropathy via CD163 Expressing Macrophage Induction.
FXR-Gankyrin axis is involved in development of pediatric liver cancer.
The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation.
Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.
Gui Y, Yu Y, Wang W, Wang Y, Lu H, Mozdzierz S, Eskander K, Lin YH, Li H, Tian XJ, Liu S, Zhou D
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23597
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Apr 15;38(7):e23597
Orosomucoid 1 promotes colorectal cancer progression and liver metastasis by affecting PI3K/AKT pathway and inducing macrophage M2 polarization.
Yue L, Xu X, Dai S, Xu F, Zhao W, Gu J, Dai X, Qian X
Scientific reports 2023 Aug 28;13(1):14092
Scientific reports 2023 Aug 28;13(1):14092
Orosomucoid 2 maintains hepatic lipid homeostasis through suppression of de novo lipogenesis.
Zhou B, Luo Y, Ji N, Hu C, Lu Y
Nature metabolism 2022 Sep;4(9):1185-1201
Nature metabolism 2022 Sep;4(9):1185-1201
Urine Proteome in Distinguishing Hepatic Steatosis in Patients with Metabolic-Associated Fatty Liver Disease.
Liu CH, Zheng S, Wang S, Wu D, Jiang W, Zeng Q, Wei Y, Zhang Y, Tang H
Diagnostics (Basel, Switzerland) 2022 Jun 7;12(6)
Diagnostics (Basel, Switzerland) 2022 Jun 7;12(6)
Thapsigargin suppresses alpha 1-acid glycoprotein secretion independently of N-glycosylation and ER stress.
Goto N, Shibutani S, Miura N, Watanabe R, Iwata H
Biochemical and biophysical research communications 2021 May 7;552:30-36
Biochemical and biophysical research communications 2021 May 7;552:30-36
Orosomucoid 1 promotes epirubicin resistance in breast cancer by upregulating the expression of matrix metalloproteinases 2 and 9.
Qiong L, Yin J
Bioengineered 2021 Dec;12(1):8822-8832
Bioengineered 2021 Dec;12(1):8822-8832
An acute phase protein α(1)-acid glycoprotein mitigates AKI and its progression to CKD through its anti-inflammatory action.
Watanabe H, Fujimura R, Hiramoto Y, Murata R, Nishida K, Bi J, Imafuku T, Komori H, Maeda H, Mukunoki A, Takeo T, Nakagata N, Tanaka M, Matsushita K, Fukagawa M, Maruyama T
Scientific reports 2021 Apr 12;11(1):7953
Scientific reports 2021 Apr 12;11(1):7953
α(1)-Acid Glycoprotein Attenuates Adriamycin-Induced Nephropathy via CD163 Expressing Macrophage Induction.
Fujimura R, Watanabe H, Nishida K, Fujiwara Y, Koga T, Bi J, Imafuku T, Kobayashi K, Komori H, Miyahisa M, Maeda H, Tanaka M, Matsushita K, Wada T, Fukagawa M, Maruyama T
Kidney360 2020 May 28;1(5):343-353
Kidney360 2020 May 28;1(5):343-353
FXR-Gankyrin axis is involved in development of pediatric liver cancer.
Valanejad L, Lewis K, Wright M, Jiang Y, D'Souza A, Karns R, Sheridan R, Gupta A, Bove K, Witte D, Geller J, Tiao G, Nelson DL, Timchenko L, Timchenko N
Carcinogenesis 2017 Jul 1;38(7):738-747
Carcinogenesis 2017 Jul 1;38(7):738-747
The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation.
Mobin MB, Gerstberger S, Teupser D, Campana B, Charisse K, Heim MH, Manoharan M, Tuschl T, Stoffel M
Nature communications 2016 Sep 26;7:12848
Nature communications 2016 Sep 26;7:12848
Identification of GlcNAcylated alpha-1-antichymotrypsin as an early biomarker in human non-small-cell lung cancer by quantitative proteomic analysis with two lectins.
Jin Y, Wang J, Ye X, Su Y, Yu G, Yang Q, Liu W, Yu W, Cai J, Chen X, Liang Y, Chen Y, Wong BH, Fu X, Sun H
British journal of cancer 2016 Mar 1;114(5):532-44
British journal of cancer 2016 Mar 1;114(5):532-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse liver tissue were subjected to SDS PAGE followed by western blot with 16439-1-AP(ORM1 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-ORM1 (IP:16439-1-AP, 3ug; Detection:16439-1-AP 1:300) with human plasma tissue lysate 100ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ORM1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ORM1. This antibody recognizes human, mouse antigen. The ORM1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
