PA5-53594

antibody from Invitrogen Antibodies

Targeting: KCNJ5 CIR, GIRK4, KATP1, Kir3.4, LQT13

Western blot (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-53594

Provider

Invitrogen Antibodies

Product name

Kir3.4 (KCNJ5) Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Recombinant protein fragment

Description

Immunogen sequence: VTPWDPKKIP KQARDYVPIA TDRTRLLAEG KKPRQRYMEK SGKCNVHHGN VQETY Highest antigen sequence identity to the following orthologs: Mouse - 89%, Rat - 89%.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

0.1 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

USP8 mutations in corticotroph adenomas determine a distinct gene expression profile irrespective of functional tumour status.

Bujko M, Kober P, Boresowicz J, Rusetska N, Paziewska A, Dąbrowska M, Piaścik A, Pękul M, Zieliński G, Kunicki J, Bonicki W, Ostrowski J, Siedlecki JA, Maksymowicz M
European journal of endocrinology 2019 Dec;181(6):615-627

Immunohistochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of Kir3.4 (KCNJ5) in human skeletal muscle using Kir3.4 (KCNJ5) Polyclonal Antibody (Product # PA5-53594) shows no positivity in myocytes as expected.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical analysis of Kir3.4 (KCNJ5) in human adrenal gland using Kir3.4 (KCNJ5) Polyclonal Antibody (Product # PA5-53594) shows moderate to strong membranous positivity in glandular cells.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Kir3.4 (KCNJ5) in human adrenal gland and cerebral cortex tissues using Kir3.4 (KCNJ5) Polyclonal Antibody (Product # PA5-53594). Corresponding KCNJ5 RNA-seq data are presented for the same tissues.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Kir3.4 (KCNJ5) in human cerebral cortex using Kir3.4 (KCNJ5) Polyclonal Antibody (Product # PA5-53594) shows low expression as expected.

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemical staining of Kir3.4 (KCNJ5) in human adrenal gland using Kir3.4 (KCNJ5) Polyclonal Antibody (Product # PA5-53594) shows high expression.