PIGF

This gene encodes a protein involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor, a glycolipid containing three mannose molecules in its core backbone, is found on many blood cells where it serves to anchor proteins to the cell surface. The encoded protein and another GPI synthesis protein, PIGO, function in the transfer of ethanolaminephosphate to the third mannose in GPI. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Description

Phosphatidylinositol glycan anchor biosynthesis class F

Tissue specificity

Low tissue specificity

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted membrane proteins

Chromosome

2 (46580937 - 46617055)

Ensembl ID

ENSG00000151665  (ver. 103.38)

Orthologs

Mouse Pigf: ENSMUSG00000024145

UniProt

Q07326

neXtProt

NX_Q07326

Human splice variants
Mouse splice variants

Protein structure