Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 12970-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12970-1-AP, RRID:AB_10638603
- Product name
- OPRL1 antibody
- Antibody type
- Polyclonal
- Description
- OPRL1 antibody (Cat. #12970-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references UFP-101 alleviates diabetic peripheral neuropathy through membrane metallo-endopeptidase.
Phenanthrene exposure disrupts puberty onset in SD rats by influencing hypothalamic neural networks.
The impact of endogenous N/OFQ on DPN: Insights into lower limb blood flow regulation in rats.
A proteogenomic tool uncovers protein markers for human microglial states.
The nociceptin receptor promotes autophagy through NF-kB signaling and is transcriptionally regulated by E2F1 in HCC.
Naltrexone (NTX) relieves inflammation in the collagen-induced- arthritis (CIA) rat models through regulating TLR4/NFκB signaling pathway.
Pharmacological blockade of CXCR3 by (±)-NBI-74330 reduces neuropathic pain and enhances opioid effectiveness - Evidence from in vivo and in vitro studies.
Minocycline enhances the effectiveness of nociceptin/orphanin FQ during neuropathic pain.
Han Y, Qin YJ, Li J, Zhang CY, Wang TQ
European journal of pharmacology 2025 Nov 15;1007:178246
European journal of pharmacology 2025 Nov 15;1007:178246
Phenanthrene exposure disrupts puberty onset in SD rats by influencing hypothalamic neural networks.
Chen Z, Zhang Q, Huang T, Zhang J, Wu D, Wu W, Tian Y, He Z, Wang W, Feng X, Wu N, Liu Q
Environmental pollution (Barking, Essex : 1987) 2025 Nov 1;384:126933
Environmental pollution (Barking, Essex : 1987) 2025 Nov 1;384:126933
The impact of endogenous N/OFQ on DPN: Insights into lower limb blood flow regulation in rats.
Qin YJ, Zhang P, Zhang P, Li J, Yang Q, Sun JL, Liang YZ, Wang LL, Zhang LZ, Han Y
Neuropeptides 2025 Jan;109:102492
Neuropeptides 2025 Jan;109:102492
A proteogenomic tool uncovers protein markers for human microglial states.
Haage V, Bautista AR, Tuddenham J, Marshe V, Chiu R, Liu Y, Lama T, Kelly SS, Parghi NA, Park J, Buonfiglioli A, Furnari JL, Haq I, Pearse R, Patel R, Terzioglu G, Touil H, Zeng L, Noble J, Sarkis RA, Shneider NA, de Witte LD, Schneider J, Teich A, Young-Pearse TL, Riley C, Bennett DA, Canoll P, Bruce JN, Howden AJM, Lloyd AF, de Strooper B, Sher F, Sproul AA, Olah M, Taga M, Zhang Y, Caisheng L, Fujita M, Petyuk VA, De Jager PL
bioRxiv : the preprint server for biology 2025 Apr 4;
bioRxiv : the preprint server for biology 2025 Apr 4;
The nociceptin receptor promotes autophagy through NF-kB signaling and is transcriptionally regulated by E2F1 in HCC.
Zhou X, Chen D, Yan Y, Li Q, Xing W, Liu Y, Chen Y, Wang D, Yuan Y, Xie J, Zeng W, Pan J
Cell death discovery 2022 Apr 5;8(1):165
Cell death discovery 2022 Apr 5;8(1):165
Naltrexone (NTX) relieves inflammation in the collagen-induced- arthritis (CIA) rat models through regulating TLR4/NFκB signaling pathway.
Xu N, Wang Y, Zhao S, Jiao T, Xue H, Shan F, Zhang N
International immunopharmacology 2020 Feb;79:106056
International immunopharmacology 2020 Feb;79:106056
Pharmacological blockade of CXCR3 by (±)-NBI-74330 reduces neuropathic pain and enhances opioid effectiveness - Evidence from in vivo and in vitro studies.
Piotrowska A, Rojewska E, Pawlik K, Kreiner G, Ciechanowska A, Makuch W, Zychowska M, Mika J
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3418-3437
Biochimica et biophysica acta. Molecular basis of disease 2018 Oct;1864(10):3418-3437
Minocycline enhances the effectiveness of nociceptin/orphanin FQ during neuropathic pain.
Popiolek-Barczyk K, Rojewska E, Jurga AM, Makuch W, Zador F, Borsodi A, Piotrowska A, Przewlocka B, Mika J
BioMed research international 2014;2014:762930
BioMed research international 2014;2014:762930
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 12970-1-AP(OPRL1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The OPRL1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human OPRL1. This antibody recognizes human, mouse, rat antigen. The OPRL1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human gliomas using 12970-1-AP(OPRL1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue