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Learn12076-1-AP
antibody from Proteintech Group
Targeting: USP48
FLJ11328, FLJ20103, FLJ23054, FLJ23277, MGC14879, USP31
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12076-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12076-1-AP, RRID:AB_2213840
- Product name
- USP48 antibody
- Antibody type
- Polyclonal
- Description
- USP48 antibody (Cat. #12076-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references USP5 inhibition enables potential therapy for t(8;21) AML through ubiquitin-mediated AML1-ETO degradation in patient-derived xenografts.
USP48 promotes NLRP3-dependent pyroptosis of alveolar macrophages to exacerbate sepsis-induced acute lung injury.
Chromatin Perturbation Promotes Susceptibility to Hypomethylating Agents.
The deubiquitinase USP24 suppresses ferroptosis in triple-negative breast cancer by stabilizing DHODH protein.
Caspase 3-specific cleavage of ubiquitin-specific peptidase 48 enhances drug-induced apoptosis in AML.
Candesartan upregulates angiotensin-converting enzyme 2 in kidneys of male animals by decreased ubiquitination.
RUNX1 regulates MCM2/CDC20 to promote COAD progression modified by deubiquitination of USP31.
Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis.
USP48 alleviates bone cancer pain and regulates MrgC stabilization in spinal cord neurons of male mice.
Overexpression of ubiquitin-specific peptidase 15 in systemic sclerosis fibroblasts increases response to transforming growth factor β.
YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis.
Ma L, Zhang K, Zhang Z, Wang C, Ma M, Liu Y, Zhao Y, Gong Z, Liu N, Wei M, Liu X, Zhou J, Liu S, Yang C, Yang G
Science translational medicine 2025 Sep 24;17(817):eadt9100
Science translational medicine 2025 Sep 24;17(817):eadt9100
USP48 promotes NLRP3-dependent pyroptosis of alveolar macrophages to exacerbate sepsis-induced acute lung injury.
Jia A, Wang Y, Zhou R, Han L
International immunopharmacology 2025 Sep 23;162:115140
International immunopharmacology 2025 Sep 23;162:115140
Chromatin Perturbation Promotes Susceptibility to Hypomethylating Agents.
Schneider C, Alexe G, Merickel LA, Meyer A, Swift ML, Serafim RB, Basanthakumar AT, Taillon A, Salhotra S, Boniolo F, Lambo S, Rodriguez Y, Häupl B, George RE, Root DE, Oellerich T, Hovestadt V, Chowdhury D, Stegmaier K
bioRxiv : the preprint server for biology 2025 Jul 31;
bioRxiv : the preprint server for biology 2025 Jul 31;
The deubiquitinase USP24 suppresses ferroptosis in triple-negative breast cancer by stabilizing DHODH protein.
Yang L, An X, Yang S, Lin X, Chen Z, Xue Q, Chen X, Wang Y, Yan D, Chen S, Fan Y, Tang D, Yu W, Liu J, Chen X
Cell death & disease 2025 Jul 26;16(1):564
Cell death & disease 2025 Jul 26;16(1):564
Caspase 3-specific cleavage of ubiquitin-specific peptidase 48 enhances drug-induced apoptosis in AML.
Zhang Z, Lin X, Yang Y, Wang X, Wang Y, Huang X, Hong M, Gao W, He H, You MJ, Yang Y, Kong G
Cancer biology & therapy 2025 Dec;26(1):2459426
Cancer biology & therapy 2025 Dec;26(1):2459426
Candesartan upregulates angiotensin-converting enzyme 2 in kidneys of male animals by decreased ubiquitination.
Wang P, Ren Z, Wang W, Liu M, Jia Y, Zhang M, Xue Y, Zhang C, Xu J, Wang C, Wang X
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23537
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Mar 31;38(6):e23537
RUNX1 regulates MCM2/CDC20 to promote COAD progression modified by deubiquitination of USP31.
Tian W, Zhao J, Zhang X, Li P, Li X, Hong Y, Li S
Scientific reports 2024 Jun 17;14(1):13906
Scientific reports 2024 Jun 17;14(1):13906
Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis.
Cheng C, Yao H, Li H, Liu J, Liu Z, Wu Y, Zhu L, Hu H, Fang Z, Wu L
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1624-1643
Acta pharmaceutica Sinica. B 2024 Apr;14(4):1624-1643
USP48 alleviates bone cancer pain and regulates MrgC stabilization in spinal cord neurons of male mice.
Yu J, Hou B, Huang Y, Wang X, Qian Y, Liang Y, Gu X, Ma Z, Sun Y
European journal of pain (London, England) 2023 Jul;27(6):723-734
European journal of pain (London, England) 2023 Jul;27(6):723-734
Overexpression of ubiquitin-specific peptidase 15 in systemic sclerosis fibroblasts increases response to transforming growth factor β.
Galant C, Marchandise J, Stoenoiu MS, Ducreux J, De Groof A, Pirenne S, Van den Eynde B, Houssiau FA, Lauwerys BR
Rheumatology (Oxford, England) 2019 Apr 1;58(4):708-718
Rheumatology (Oxford, England) 2019 Apr 1;58(4):708-718
YAP1-Mediated Suppression of USP31 Enhances NFκB Activity to Promote Sarcomagenesis.
Ye S, Lawlor MA, Rivera-Reyes A, Egolf S, Chor S, Pak K, Ciotti GE, Lee AC, Marino GE, Shah J, Niedzwicki D, Weber K, Park PMC, Alam MZ, Grazioli A, Haldar M, Xu M, Perry JA, Qi J, Eisinger-Mathason TSK
Cancer research 2018 May 15;78(10):2705-2720
Cancer research 2018 May 15;78(10):2705-2720
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 12076-1-AP(USP48 antibody) at dilution of 1:300
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The USP48 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human USP48. This antibody recognizes human, mouse, rat antigen. The USP48 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
