Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA013835 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA013835, RRID:AB_1847214
- Product name
- Anti-CRB3
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human CRB3, Gene description: crumbs family member 3, Alternative Gene Names: MGC17303, Validated applications: ICC, IHC, Uniprot ID: Q9BUF7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
Submitted references CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis
Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins
Crumbs protein homolog 3 (CRB3) expression is associated with oestrogen and progesterone receptor positivity in breast cancer
Distinct functions of Crumbs regulating slit diaphragms and endocytosis in Drosophila nephrocytes
CRB3 downregulation confers breast cancer stem cell traits through TAZ/β-catenin
Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation
Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo.
A critical role for NF2 and the Hippo pathway in branching morphogenesis
Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
Yap and Taz are required for Ret-dependent urinary tract morphogenesis
Liang Z, Wang B, Tan T, Zhang M, Jiang Y, Shang Y, Gao X, Song S, Wang R, Chen H, Liu J, Li J, Ren Y, Liu P
eLife 2023;12
eLife 2023;12
Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins
Dho S, Silva-Gagliardi N, Morgese F, Coyaud E, Lamoureux E, Berry D, Raught B, McGlade C
Scientific Reports 2019;9(1)
Scientific Reports 2019;9(1)
Crumbs protein homolog 3 (CRB3) expression is associated with oestrogen and progesterone receptor positivity in breast cancer
Li P, Zhou C, Yan Y, Li J, Liu J, Zhang Y, Liu P
Clinical and Experimental Pharmacology and Physiology 2019;46(9):837-844
Clinical and Experimental Pharmacology and Physiology 2019;46(9):837-844
Distinct functions of Crumbs regulating slit diaphragms and endocytosis in Drosophila nephrocytes
Hochapfel F, Denk L, Mendl G, Schulze U, Maaßen C, Zaytseva Y, Pavenstädt H, Weide T, Rachel R, Witzgall R, Krahn M
Cellular and Molecular Life Sciences 2017;74(24):4573-4586
Cellular and Molecular Life Sciences 2017;74(24):4573-4586
CRB3 downregulation confers breast cancer stem cell traits through TAZ/β-catenin
Li P, Wang Y, Mao X, Jiang Y, Liu J, Li J, Wang J, Wang R, She J, Zhang J, Yang J, Liu Y, Liu P
Oncogenesis 2017;6(4):e322-e322
Oncogenesis 2017;6(4):e322-e322
Lats1/2 Regulate Yap/Taz to Control Nephron Progenitor Epithelialization and Inhibit Myofibroblast Formation
McNeill H, Reginensi A
Journal of the American Society of Nephrology 2017;28(3):852-861
Journal of the American Society of Nephrology 2017;28(3):852-861
Actomyosin polarisation through PLC-PKC triggers symmetry breaking of the mouse embryo.
Zhu M, Leung CY, Shahbazi MN, Zernicka-Goetz M
Nature communications 2017 Oct 13;8(1):921
Nature communications 2017 Oct 13;8(1):921
A critical role for NF2 and the Hippo pathway in branching morphogenesis
Reginensi A, Enderle L, Gregorieff A, Johnson R, Wrana J, McNeill H
Nature Communications 2016;7(1)
Nature Communications 2016;7(1)
Polarity protein Crumbs homolog-3 (CRB3) regulates ectoplasmic specialization dynamics through its action on F-actin organization in Sertoli cells
Gao Y, Lui W, Lee W, Cheng C
Scientific Reports 2016;6(1)
Scientific Reports 2016;6(1)
Modelling kidney disease with CRISPR-mutant kidney organoids derived from human pluripotent epiblast spheroids
Freedman B, Brooks C, Lam A, Fu H, Morizane R, Agrawal V, Saad A, Li M, Hughes M, Werff R, Peters D, Lu J, Baccei A, Siedlecki A, Valerius M, Musunuru K, McNagny K, Steinman T, Zhou J, Lerou P, Bonventre J
Nature Communications 2015;6(1)
Nature Communications 2015;6(1)
Yap and Taz are required for Ret-dependent urinary tract morphogenesis
Reginensi A, Hoshi M, Boualia S, Bouchard M, Jain S, McNeill H
Development 2015;142(15):2696-2703
Development 2015;142(15):2696-2703
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human kidney and cerebral cortex tissues using HPA013835 antibody. Corresponding CRB3 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol