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- References [14]
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- Immunohistochemistry [1]
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- Product number
- 11497-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- Apelin antibody
- Antibody type
- Polyclonal
- Description
- Apelin antibody (Cat. #11497-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exercise ameliorates osteopenia in mice via intestinal microbial-mediated bile acid metabolism pathway.
Apelin/APJ alleviates diabetic nephropathy by improving glomerular endothelial cells dysfunction via SIRT3‑KLF15.
Single-cell analysis reveals the implication of vascular endothelial cell-intrinsic ANGPT2 in human intracranial aneurysm.
Single-cell RNA sequencing and spatial transcriptomics of esophageal squamous cell carcinoma with lymph node metastases.
Targeted delivery of apelin using a novel extracellular vesicle platform for pulmonary arterial hypertension treatment.
Mesenchymal Stem Cell-based Apelin Gene Therapy Improves Pulmonary Artery Remodeling in Monocrotaline-induced Pulmonary Hypertension Through PI3K/AKT/eNOS and ERK1/2 Signaling Pathways.
Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism.
Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.
Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK signaling pathway.
Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis.
Maternal exercise via exerkine apelin enhances brown adipogenesis and prevents metabolic dysfunction in offspring mice.
Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway.
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
The Hippocampus is a Critical Site Mediating Antidepressant-like Activity of Apelin-13 in Rats.
Yu C, Sun R, Yang W, Gu T, Ying X, Ye L, Zheng Y, Fan S, Zeng X, Yao S
Theranostics 2025;15(5):1741-1759
Theranostics 2025;15(5):1741-1759
Apelin/APJ alleviates diabetic nephropathy by improving glomerular endothelial cells dysfunction via SIRT3‑KLF15.
Huang M, Chang J, Liu Y, Yin J, Zeng X
Molecular medicine reports 2025 May;31(5)
Molecular medicine reports 2025 May;31(5)
Single-cell analysis reveals the implication of vascular endothelial cell-intrinsic ANGPT2 in human intracranial aneurysm.
Yu G, Li J, Zhang H, Zi H, Liu M, An Q, Qiu T, Li P, Song J, Liu P, Quan K, Li S, Liu Y, Zhu W, Du J
Cardiovascular research 2025 May 6;121(4):658-673
Cardiovascular research 2025 May 6;121(4):658-673
Single-cell RNA sequencing and spatial transcriptomics of esophageal squamous cell carcinoma with lymph node metastases.
Guo W, Zhou B, Dou L, Guo L, Li Y, Qin J, Wang Z, Huai Q, Xue X, Li Y, Ying J, Xue Q, Gao S, He J
Experimental & molecular medicine 2025 Feb;57(1):59-71
Experimental & molecular medicine 2025 Feb;57(1):59-71
Targeted delivery of apelin using a novel extracellular vesicle platform for pulmonary arterial hypertension treatment.
Kim J, Choi YS, Kim J, Wahab R, Lee Y, Joo H, Park S, Lee I, Kim SA, Hwang YH, Cho S, Goo J, Jeong C, Park SY, Kim GB, Al-Hilal TA, Nam GH, Kim IS
Biomaterials 2025 Dec;323:123438
Biomaterials 2025 Dec;323:123438
Mesenchymal Stem Cell-based Apelin Gene Therapy Improves Pulmonary Artery Remodeling in Monocrotaline-induced Pulmonary Hypertension Through PI3K/AKT/eNOS and ERK1/2 Signaling Pathways.
Wang L, Wang W, Wu T, Chen L, Zong G
Journal of cardiovascular translational research 2025 Aug;18(4):723-737
Journal of cardiovascular translational research 2025 Aug;18(4):723-737
Maternal exercise improves epithelial development of fetal intestine by enhancing apelin signaling and oxidative metabolism.
Chae SA, Son JS, de Avila JM, Du M, Zhu MJ
American journal of physiology. Regulatory, integrative and comparative physiology 2022 Nov 1;323(5):R728-R738
American journal of physiology. Regulatory, integrative and comparative physiology 2022 Nov 1;323(5):R728-R738
Maternal exercise intergenerationally drives muscle-based thermogenesis via activation of apelin-AMPK signaling.
Son JS, Chae SA, Zhao L, Wang H, de Avila JM, Zhu MJ, Jiang Z, Du M
EBioMedicine 2022 Feb;76:103842
EBioMedicine 2022 Feb;76:103842
Apelin-13 induces mitophagy in bone marrow mesenchymal stem cells to suppress intracellular oxidative stress and ameliorate osteoporosis by activation of AMPK signaling pathway.
Chen L, Shi X, Xie J, Weng SJ, Xie ZJ, Tang JH, Yan DY, Wang BZ, Fang KH, Hong CX, Wu ZY, Yang L
Free radical biology & medicine 2021 Feb 1;163:356-368
Free radical biology & medicine 2021 Feb 1;163:356-368
Maternal Inactivity Programs Skeletal Muscle Dysfunction in Offspring Mice by Attenuating Apelin Signaling and Mitochondrial Biogenesis.
Son JS, Chae SA, Wang H, Chen Y, Bravo Iniguez A, de Avila JM, Jiang Z, Zhu MJ, Du M
Cell reports 2020 Dec 1;33(9):108461
Cell reports 2020 Dec 1;33(9):108461
Maternal exercise via exerkine apelin enhances brown adipogenesis and prevents metabolic dysfunction in offspring mice.
Son JS, Zhao L, Chen Y, Chen K, Chae SA, de Avila JM, Wang H, Zhu MJ, Jiang Z, Du M
Science advances 2020 Apr;6(16):eaaz0359
Science advances 2020 Apr;6(16):eaaz0359
Apelin-13 Suppresses Neuroinflammation Against Cognitive Deficit in a Streptozotocin-Induced Rat Model of Alzheimer's Disease Through Activation of BDNF-TrkB Signaling Pathway.
Luo H, Xiang Y, Qu X, Liu H, Liu C, Li G, Han L, Qin X
Frontiers in pharmacology 2019;10:395
Frontiers in pharmacology 2019;10:395
Apelin-13 Upregulates BDNF Against Chronic Stress-induced Depression-like Phenotypes by Ameliorating HPA Axis and Hippocampal Glucocorticoid Receptor Dysfunctions.
Dai TT, Wang B, Xiao ZY, You Y, Tian SW
Neuroscience 2018 Oct 15;390:151-159
Neuroscience 2018 Oct 15;390:151-159
The Hippocampus is a Critical Site Mediating Antidepressant-like Activity of Apelin-13 in Rats.
Xiao ZY, Wang B, Fu W, Jin X, You Y, Tian SW, Kuang X
Neuroscience 2018 Apr 1;375:1-9
Neuroscience 2018 Apr 1;375:1-9
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Apelin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Apelin. This antibody recognizes human,mouse,rat antigen. The Apelin antibody has been validated for the following applications: ELISA, IHC analysis.
