Antibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 25244-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- PHLPPL antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PHLPPL antibody (Cat. #25244-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Reduced PHLPP Expression Leads to EGFR-TKI Resistance in Lung Cancer by Activating PI3K-AKT and MAPK-ERK Dual Signaling.
Role of epigenetic m6 A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR-AKT signaling.
LncRNA MBNL1-AS1 represses cell proliferation and enhances cell apoptosis via targeting miR-135a-5p/PHLPP2/FOXO1 axis in bladder cancer.
miR-762 Promotes Malignant Development of Head and Neck Squamous Cell Carcinoma by Targeting PHLPP2 and FOXO4.
PHLPP2 as a novel metastatic and prognostic biomarker in non-small cell lung cancer patients.
PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells.
High PHLPP1 expression levels predicts longer time of acquired resistance to EGFR tyrosine kinase inhibitors in patients with lung adenocarcinoma.
PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells.
Wang W, Xia X, Chen K, Chen M, Meng Y, Lv D, Yang H
Frontiers in oncology 2021;11:665045
Frontiers in oncology 2021;11:665045
Role of epigenetic m6 A RNA methylation in vascular development: mettl3 regulates vascular development through PHLPP2/mTOR-AKT signaling.
Parial R, Li H, Li J, Archacki S, Yang Z, Wang IZ, Chen Q, Xu C, Wang QK
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21465
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 May;35(5):e21465
LncRNA MBNL1-AS1 represses cell proliferation and enhances cell apoptosis via targeting miR-135a-5p/PHLPP2/FOXO1 axis in bladder cancer.
Wei X, Yang X, Wang B, Yang Y, Fang Z, Yi C, Shi L, Song D
Cancer medicine 2020 Jan;9(2):724-736
Cancer medicine 2020 Jan;9(2):724-736
miR-762 Promotes Malignant Development of Head and Neck Squamous Cell Carcinoma by Targeting PHLPP2 and FOXO4.
Chen S, Zhang JY, Sun LS, Li XF, Bai JY, Zhang HY, Li TJ
OncoTargets and therapy 2019;12:11425-11436
OncoTargets and therapy 2019;12:11425-11436
PHLPP2 as a novel metastatic and prognostic biomarker in non-small cell lung cancer patients.
Wang H, Gu R, Tian F, Liu Y, Fan W, Xue G, Cai L, Xing Y
Thoracic cancer 2019 Nov;10(11):2124-2132
Thoracic cancer 2019 Nov;10(11):2124-2132
PHLPP regulates hexokinase 2-dependent glucose metabolism in colon cancer cells.
Xiong X, Wen YA, Mitov MI, C Oaks M, Miyamoto S, Gao T
Cell death discovery 2017;3:16103
Cell death discovery 2017;3:16103
High PHLPP1 expression levels predicts longer time of acquired resistance to EGFR tyrosine kinase inhibitors in patients with lung adenocarcinoma.
Xie Y, Lv D, Wang W, Ye M, Chen X, Yang H
Oncotarget 2017 Aug 29;8(35):59000-59007
Oncotarget 2017 Aug 29;8(35):59000-59007
PHLPP negatively regulates cell motility through inhibition of Akt activity and integrin expression in pancreatic cancer cells.
Smith AJ, Wen YA, Stevens PD, Liu J, Wang C, Gao T
Oncotarget 2016 Feb 16;7(7):7801-15
Oncotarget 2016 Feb 16;7(7):7801-15
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- NIH/3T3 cells were subjected to SDS PAGE followed by western blot with 25244-1-AP( PHLPPL Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PHLPPL antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human PHLPPL. This antibody recognizes human, mouse, rat antigen. The PHLPPL antibody has been validated for the following applications: ELISA, WB, IF, IHC analysis.