24876-1-AP

antibody from Proteintech Group

Targeting: TREX1 AGS1, DRN3

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

24876-1-AP

Provider

Proteintech Group

Product name

TREX1 antibody

Antibody type

Polyclonal

Description

TREX1 antibody (Cat. #24876-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IP, WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

S-nitrosation in endothelium: different outcomes of NRF2 and GSNOR loss.

Kopacz A, Kloska D, Kraszewska I, Targosz-Korecka M, Kubisiak A, Jankowska U, Skupien-Rabian B, Grochot-Przeczek A, Jozkowicz A
Free radical biology & medicine 2026 Feb 16;244:323-335

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Two rare mutations in homozygosity synergize to silence TREX1 in Aicardi-Goutières syndrome.

Rubin T, Bernier S, Hoon Lim LS, Salman MS, Leung E, Mhanni A, Marles S, Greenberg C, Perez A, Sun Y, Angers I, Vinh DC, Roussel L
Frontiers in immunology 2025;16:1557632

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Inactivation of Myostatin Delays Senescence via TREX1-SASP in Bovine Skeletal Muscle Cells.

Yang M, Gao L, Gao Y, Hao Z, Zhou X, Su G, Bai C, Wei Z, Liu X, Yang L, Li G
International journal of molecular sciences 2024 May 12;25(10)

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Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition.

Li Y, Shen S, Guo H, Li H, Zhang L, Zhang B, Yu XF, Wei W
Cell reports 2024 Feb 27;43(2):113749

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Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection.

King CR, Liu Y, Amato KA, Schaack GA, Mickelson C, Sanders AE, Hu T, Gupta S, Langlois RA, Smith JA, Mehle A
Cell host & microbe 2023 Sep 13;31(9):1552-1567.e8

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Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection.

King CR, Liu Y, Amato KA, Schaack GA, Hu T, Smith JA, Mehle A
bioRxiv : the preprint server for biology 2023 Feb 7;

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Retinal Vasculopathy With Cerebral Leukodystrophy: Clinicopathologic Features of an Autopsied Patient With a Heterozygous TREX 1 Mutation.

Saito R, Nozaki H, Kato T, Toyoshima Y, Tanaka H, Tsubata Y, Morioka T, Horikawa Y, Oyanagi K, Morita T, Onodera O, Kakita A
Journal of neuropathology and experimental neurology 2019 Feb 1;78(2):181-186

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The TREX1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human TREX1. This antibody recognizes human antigen. The TREX1 antibody has been validated for the following applications: ELISA, WB analysis.

Appendix

24876-1-AP.pdf

Show more

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HepG2 cells were subjected to SDS PAGE followed by western blot with 24876-1-AP( TREX1 Antibody) at dilution of 1:300

Sample type

cell line