AMM01875G

antibody from Leading Biology

Targeting: PEG10 HB-1, KIAA1051, Mar2, Mart2, MEF3L, RGAG3, RTL2, SIRH1

Western blot (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM01875G

Provider

Leading Biology

Product name

EDR / PEG10 Antibody (clone 1B1C4)

Antibody type

Monoclonal

Description

Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity).

Reactivity

Human

Host

Mouse

Antibody clone number

1B1C4

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.