Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
- Flow cytometry [1]
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Validation data
Reference
Comment
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- Product number
- 18160-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18160-1-AP, RRID:AB_2073200
- Product name
- TEM1 antibody
- Antibody type
- Polyclonal
- Description
- TEM1 antibody (Cat. #18160-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references CD248 as a novel therapeutic target in pulmonary arterial hypertension.
Interaction with CD68 and Regulation of GAS6 Expression by Endosialin in Fibroblasts Drives Recruitment and Polarization of Macrophages in Hepatocellular Carcinoma.
Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation.
Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma.
TGFβ-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
Identification of a candidate proteomic signature to discriminate multipotent and non-multipotent stromal cells.
Xu T, Shao L, Wang A, Liang R, Lin Y, Wang G, Zhao Y, Hu J, Liu S
Clinical and translational medicine 2020 Sep;10(5):e175
Clinical and translational medicine 2020 Sep;10(5):e175
Interaction with CD68 and Regulation of GAS6 Expression by Endosialin in Fibroblasts Drives Recruitment and Polarization of Macrophages in Hepatocellular Carcinoma.
Yang F, Wei Y, Han D, Li Y, Shi S, Jiao D, Wu J, Zhang Q, Shi C, Yang L, Song W, Zhang J, Han Y, Zhang R, Yang AG, Dimitrov DS, Zhao A, Qin W, Wen W
Cancer research 2020 Sep 15;80(18):3892-3905
Cancer research 2020 Sep 15;80(18):3892-3905
Specific loss of adipocyte CD248 improves metabolic health via reduced white adipose tissue hypoxia, fibrosis and inflammation.
Petrus P, Fernandez TL, Kwon MM, Huang JL, Lei V, Safikhan NS, Karunakaran S, O'Shannessy DJ, Zheng X, Catrina SB, Albone E, Laine J, Virtanen K, Clee SM, Kieffer TJ, Noll C, Carpentier AC, Johnson JD, Rydén M, Conway EM
EBioMedicine 2019 Jun;44:489-501
EBioMedicine 2019 Jun;44:489-501
Generation of a novel Antibody-Drug Conjugate targeting endosialin: potent and durable antitumor response in sarcoma.
Capone E, Piccolo E, Fichera I, Ciufici P, Barcaroli D, Sala A, De Laurenzi V, Iacobelli V, Iacobelli S, Sala G
Oncotarget 2017 Sep 1;8(36):60368-60377
Oncotarget 2017 Sep 1;8(36):60368-60377
TGFβ-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
Suresh Babu S, Valdez Y, Xu A, O'Byrne AM, Calvo F, Lei V, Conway EM
BMC cancer 2014 Feb 20;14:113
BMC cancer 2014 Feb 20;14:113
Identification of a candidate proteomic signature to discriminate multipotent and non-multipotent stromal cells.
Rosu-Myles M, She YM, Fair J, Muradia G, Mehic J, Menendez P, Prasad SS, Cyr TD
PloS one 2012;7(6):e38954
PloS one 2012;7(6):e38954
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 18160-1-AP(CD248 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 18160-1-AP(CD248 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung cancer using 18160-1-AP(CD248 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TEM1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TEM1. This antibody recognizes human,mouse,rat antigen. The TEM1 antibody has been validated for the following applications: ELISA, WB, IHC, FC analysis.