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- Antibody Data
- Antigen structure
- References [19]
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- Immunohistochemistry [2]
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- Product number
- 16546-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16546-1-AP, RRID:AB_2089685
- Product name
- CYP2C8/9/18/19 antibody
- Antibody type
- Polyclonal
- Description
- CYP2C8/9/18/19 antibody (Cat. #16546-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The interplay of inflammation and placenta in maternal diabetes: insights into Hofbauer cell expression patterns.
Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo.
Arachidonic acid metabolism CYP450 pathway is deregulated in hepatocellular carcinoma and associated with microvascular invasion.
Eight Zhes Decoction ameliorates the lipid dysfunction of nonalcoholic fatty liver disease using integrated lipidomics, network pharmacology and pharmacokinetics.
Impact of tectoridin on the pharmacokinetics of florfenicol via targeting cytochrome P450 and P-glycoprotein of rats.
Coptisine modulates the pharmacokinetics of florfenicol by targeting CYP1A2, CYP2C11 and CYP3A1 in the liver and P-gp in the jejunum of rats: a pilot study.
Differentiation of umbilical cord mesenchymal stem cells into hepatocytes with CYP450 metabolic enzyme activity induced by a liver injury microenvironment.
Novel Prognostic Signatures of Hepatocellular Carcinoma Based on Metabolic Pathway Phenotypes.
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Mechanism of Paeoniflorin on ANIT-Induced Cholestatic Liver Injury Using Integrated Metabolomics and Network Pharmacology.
Prognostic Value and Correlation With Tumor Immune Infiltration of a Novel Metabolism-Related Gene Signature in Pancreatic Cancer.
Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL-35.
Comparative Analysis of Immunohistochemical Staining Intensity Determined by Light Microscopy, ImageJ and QuPath in Placental Hofbauer Cells.
A novel four-gene of iron metabolism-related and methylated for prognosis prediction of hepatocellular carcinoma.
Identification of rhythmic human CYPs and their circadian regulators using synchronized hepatoma cells.
Time-dependent expression pattern of cytochrome P450 epoxygenases and soluble epoxide hydrolase in normal human placenta.
Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation.
Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer.
Time-dependent expression of cytochrome p450 epoxygenases during human prenatal development.
Tauber Z, Burianova A, Koubova K, Mrstik M, Jirkovska M, Cizkova K
Frontiers in immunology 2024;15:1386528
Frontiers in immunology 2024;15:1386528
Gemfibrozil-Platinum(IV) Precursors for New Enhanced-Starvation and Chemotherapy In Vitro and In Vivo.
Song XQ, Guo X, Ding YX, Han YX, You ZH, Song Y, Yuan Y, Li L
Journal of medicinal chemistry 2024 May 9;67(9):7033-7047
Journal of medicinal chemistry 2024 May 9;67(9):7033-7047
Arachidonic acid metabolism CYP450 pathway is deregulated in hepatocellular carcinoma and associated with microvascular invasion.
Wang K, Shi JH, Gao J, Sun Y, Wang Z, Shi X, Guo W, Jin Y, Zhang S
Cell biology international 2024 Jan;48(1):31-45
Cell biology international 2024 Jan;48(1):31-45
Eight Zhes Decoction ameliorates the lipid dysfunction of nonalcoholic fatty liver disease using integrated lipidomics, network pharmacology and pharmacokinetics.
Zhou Y, Dai Z, Deng K, Wang Y, Ying J, Chu D, Zhou J, Tang C
Journal of pharmaceutical analysis 2023 Sep;13(9):1058-1069
Journal of pharmaceutical analysis 2023 Sep;13(9):1058-1069
Impact of tectoridin on the pharmacokinetics of florfenicol via targeting cytochrome P450 and P-glycoprotein of rats.
Zhang M, Wang B, Li XT, Yin Q, Liang G, Li SC
Xenobiotica; the fate of foreign compounds in biological systems 2023 May;53(5):429-437
Xenobiotica; the fate of foreign compounds in biological systems 2023 May;53(5):429-437
Coptisine modulates the pharmacokinetics of florfenicol by targeting CYP1A2, CYP2C11 and CYP3A1 in the liver and P-gp in the jejunum of rats: a pilot study.
Li SC, Zhang M, Wang B, Li XT, Liang G
Xenobiotica; the fate of foreign compounds in biological systems 2023 Mar;53(3):207-214
Xenobiotica; the fate of foreign compounds in biological systems 2023 Mar;53(3):207-214
Differentiation of umbilical cord mesenchymal stem cells into hepatocytes with CYP450 metabolic enzyme activity induced by a liver injury microenvironment.
Xue G, Zhang J, Wu L, Sun S, Wu H, Hou Y, Wang J
Biochemical and biophysical research communications 2023 Mar 5;647:47-54
Biochemical and biophysical research communications 2023 Mar 5;647:47-54
Novel Prognostic Signatures of Hepatocellular Carcinoma Based on Metabolic Pathway Phenotypes.
Ye T, Lin L, Cao L, Huang W, Wei S, Shan Y, Zhang Z
Frontiers in oncology 2022;12:863266
Frontiers in oncology 2022;12:863266
3D two-photon brain imaging reveals dihydroartemisinin exerts antiepileptic effects by modulating iron homeostasis.
Shao C, Liu Y, Chen Z, Qin Y, Wang X, Wang X, Yan C, Zhu HL, Zhao J, Qian Y
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Cell chemical biology 2022 Jan 20;29(1):43-56.e12
Mechanism of Paeoniflorin on ANIT-Induced Cholestatic Liver Injury Using Integrated Metabolomics and Network Pharmacology.
Chen L, Zhao X, Wei S, Ma X, Liu H, Li J, Jing M, Wang M, Zhao Y
Frontiers in pharmacology 2021;12:737630
Frontiers in pharmacology 2021;12:737630
Prognostic Value and Correlation With Tumor Immune Infiltration of a Novel Metabolism-Related Gene Signature in Pancreatic Cancer.
Chen H, Zu F, Zeng T, Chen Z, Wei J, Liu P, Li Z, Zhou L, Wang H, Tan H, Tan X
Frontiers in oncology 2021;11:757791
Frontiers in oncology 2021;11:757791
Assessing CYP2C8-Mediated Pharmaceutical Excipient-Drug Interaction Potential: A Case Study of Tween 80 and Cremophor EL-35.
Wen C, Hu H, Zhang W, Liu X, Jiang X, Wang L
Pharmaceutics 2021 Sep 17;13(9)
Pharmaceutics 2021 Sep 17;13(9)
Comparative Analysis of Immunohistochemical Staining Intensity Determined by Light Microscopy, ImageJ and QuPath in Placental Hofbauer Cells.
Cizkova K, Foltynkova T, Gachechiladze M, Tauber Z
Acta histochemica et cytochemica 2021 Feb 25;54(1):21-29
Acta histochemica et cytochemica 2021 Feb 25;54(1):21-29
A novel four-gene of iron metabolism-related and methylated for prognosis prediction of hepatocellular carcinoma.
Shen H, Wu H, Sun F, Qi J, Zhu Q
Bioengineered 2021 Dec;12(1):240-251
Bioengineered 2021 Dec;12(1):240-251
Identification of rhythmic human CYPs and their circadian regulators using synchronized hepatoma cells.
Chen M, Zhou C, Zhang T, Wu B
Xenobiotica; the fate of foreign compounds in biological systems 2020 Sep;50(9):1052-1063
Xenobiotica; the fate of foreign compounds in biological systems 2020 Sep;50(9):1052-1063
Time-dependent expression pattern of cytochrome P450 epoxygenases and soluble epoxide hydrolase in normal human placenta.
Cizkova K, Tauber Z
Acta histochemica 2018 Aug;120(6):513-519
Acta histochemica 2018 Aug;120(6):513-519
Hyperhomocysteinemia results from and promotes hepatocellular carcinoma via CYP450 metabolism by CYP2J2 DNA methylation.
Zhang D, Lou J, Zhang X, Zhang L, Wang F, Xu D, Niu N, Wang Y, Wu Y, Cui W
Oncotarget 2017 Feb 28;8(9):15377-15392
Oncotarget 2017 Feb 28;8(9):15377-15392
Elevated 14,15- epoxyeicosatrienoic acid by increasing of cytochrome P450 2C8, 2C9 and 2J2 and decreasing of soluble epoxide hydrolase associated with aggressiveness of human breast cancer.
Wei X, Zhang D, Dou X, Niu N, Huang W, Bai J, Zhang G
BMC cancer 2014 Nov 18;14:841
BMC cancer 2014 Nov 18;14:841
Time-dependent expression of cytochrome p450 epoxygenases during human prenatal development.
Cizkova K, Konieczna A, Erdosova B, Ehrmann J
Organogenesis 2014 Jan 1;10(1):53-61
Organogenesis 2014 Jan 1;10(1):53-61
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 16546-1-AP(CYP2C8 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CYP2C8 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CYP2C8. This antibody recognizes human antigen. The CYP2C8 antibody has been validated for the following applications: ELISA, IHC analysis.
