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Western blot
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- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- ABIN500172 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Scavenger Receptor Class B, Member 2 (SCARB2) (Center) antibody
- Antibody type
- Polyclonal
- Antigen
- LIMP2 antibody was raised against a 16 amino acid peptide from near the center of human LIMP2.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- Center
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase.
Deafness in LIMP2-deficient mice due to early loss of the potassium channel KCNQ1/KCNE1 in marginal cells of the stria vascularis.
LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice.
Isolation and sequencing of a cDNA clone encoding 85kDa sialoglycoprotein in rat liver lysosomal membranes.
Reczek D, Schwake M, Schröder J, Hughes H, Blanz J, Jin X, Brondyk W, Van Patten S, Edmunds T, Saftig P
Cell 2007 Nov 16;131(4):770-83
Cell 2007 Nov 16;131(4):770-83
Deafness in LIMP2-deficient mice due to early loss of the potassium channel KCNQ1/KCNE1 in marginal cells of the stria vascularis.
Knipper M, Claussen C, Rüttiger L, Zimmermann U, Lüllmann-Rauch R, Eskelinen EL, Schröder J, Schwake M, Saftig P
The Journal of physiology 2006 Oct 1;576(Pt 1):73-86
The Journal of physiology 2006 Oct 1;576(Pt 1):73-86
LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice.
Gamp AC, Tanaka Y, Lüllmann-Rauch R, Wittke D, D'Hooge R, De Deyn PP, Moser T, Maier H, Hartmann D, Reiss K, Illert AL, von Figura K, Saftig P
Human molecular genetics 2003 Mar 15;12(6):631-46
Human molecular genetics 2003 Mar 15;12(6):631-46
Isolation and sequencing of a cDNA clone encoding 85kDa sialoglycoprotein in rat liver lysosomal membranes.
Fujita H, Ezaki J, Noguchi Y, Kono A, Himeno M, Kato K
Biochemical and biophysical research communications 1991 Jul 31;178(2):444-52
Biochemical and biophysical research communications 1991 Jul 31;178(2):444-52
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of LIMP2 in human skeletal muscle tissue lysate with AP30507PU-N at 1 ?g/ml in (A) the absence and (B) presence of blocking peptide.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunohistochemistry of LIMP2 in human skeletal muscle with AP30507PU-N at 2.5 ?g/ml.
