BS7140

antibody from Bioworld Technology, Inc

Targeting: IFNAR1 IFNAR, IFRC

Immunohistochemistry

Antibody data

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Validation data

Product number: BS7140 - Provider product page
Provider: Bioworld Technology, Inc
Product name: IFN R1 polyclonal antibody
Antibody type: Polyclonal
Antigen: Recombinant full length Human IFN-R1.
Description: The type I interferons, IFN-Ï« and IFN-ÉÇ, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-Ï« and IFN-ÉÇ appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-ÎÛ) binds to a distinct receptor. This distinct receptor, IFN-Ï«R, is only weakly responsive to type I interferons, in contrast to IFN-Ï«/ÉÇR, which binds to and responds effectively to IFN-ÉÇ and to several of the IFN-Ï« subtypes. IFN-Ï«/ÉÇR is expressed as two alternatively spliced transcripts, designated IFN-Ï«/ÉÇRÏ« (IFN-Ï«/ÉÇR1) and IFN-Ï«/ÉÇRÉÇ (IFN- Ï«/ÉÇR2), both of which are involved in signal transduction and ligand binding.
Reactivity: Human
Host: Rabbit
Isotype: IgG
Vial size: 100ul
Concentration: 1 mg/ml
Storage: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

IFNAR1 protein structure - BS7140 shown in red.