Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Blocking/Neutralizing [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- AF3039 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IFN-alpha/beta R1 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects mouse IFN-alpha/beta R1 in direct ELISAs and Western blots. In direct ELISAs, less than 2% cross-reactivity with recombinant mouse (rm) IFN-alpha/beta R2, rmIFN-gamma R1, and rmIFN-gamma R2 is observed.
- Reactivity
- Mouse
- Host
- Goat
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Toll-like receptor (TLR)2 and TLR3 synergy and cross-inhibition in murine myeloid dendritic cells.
Vanhoutte F, Paget C, Breuilh L, Fontaine J, Vendeville C, Goriely S, Ryffel B, Faveeuw C, Trottein F
Immunology letters 2008 Feb 15;116(1):86-94
Immunology letters 2008 Feb 15;116(1):86-94
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Limitin Inhibition of EMCV-induced Cytopathy and Neutralization by Mouse IFN-alpha/beta R1 Antibody. Recombinant Mouse Limitin (Catalog # 1535-LM) reduces the Encephalomyocarditis Virus (EMCV)-induced cytopathy in the L-929 mouse fibroblast cell line in a dose-dependent manner (orange line). Inhibition of EMCV activity elicited by Recombinant Mouse Limitin (30 pg/mL) is neutralized (green line) by increasing concentrations of Mouse IFN-alpha/beta R1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3039). The ND50 is typically 1-4 µg/mL.