Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Flow cytometry [1]
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- Product number
- FAB245A - Provider product page
- Provider
- R&D Systems
- Product name
- Human IFN-alpha/beta R1 APC-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human IFN-alpha/beta R1 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) IFN-gamma R1, rhIFN-gamma R2, recombinant mouse IFN-alpha/beta R2, rhIL-10 R beta , rhIL-10 R alpha , or rhIL-20 R beta .
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Red dye
- Antigen sequence
AAA52730
- Isotype
- IgG
- Antibody clone number
- 85228
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Endothelial cell functions impaired by interferon in vitro: Insights into the molecular mechanism of thrombotic microangiopathy associated with interferon therapy.
Hepatitis B Virus e Antigen Activates the Suppressor of Cytokine Signaling 2 to Repress Interferon Action.
Tyrosine kinase 2 is not limiting human antiviral type III interferon responses.
Jia H, Thelwell C, Dilger P, Bird C, Daniels S, Wadhwa M
Thrombosis research 2018 Mar;163:105-116
Thrombosis research 2018 Mar;163:105-116
Hepatitis B Virus e Antigen Activates the Suppressor of Cytokine Signaling 2 to Repress Interferon Action.
Yu Y, Wan P, Cao Y, Zhang W, Chen J, Tan L, Wang Y, Sun Z, Zhang Q, Wan Y, Zhu Y, Liu F, Wu K, Liu Y, Wu J
Scientific reports 2017 May 11;7(1):1729
Scientific reports 2017 May 11;7(1):1729
Tyrosine kinase 2 is not limiting human antiviral type III interferon responses.
Fuchs S, Kaiser-Labusch P, Bank J, Ammann S, Kolb-Kokocinski A, Edelbusch C, Omran H, Ehl S
European journal of immunology 2016 Nov;46(11):2639-2649
European journal of immunology 2016 Nov;46(11):2639-2649
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of IFN-alpha/beta R1 in Human U927 cell line by Flow Cytometry. U937 human histiocytic lymphoma cell line was stained with Mouse Anti-Human IFN-alpha/beta R1 APC-conjugated Monoclonal Antibody (Catalog # FAB245A, filled histogram) or isotype control antibody (Catalog # IC002A, open histogram). View our protocol for Staining Membrane-associated Proteins.