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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- FAB245P - Provider product page
- Provider
- R&D Systems
- Product name
- Human IFN-alpha/beta R1 PE-conjugated Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified from hybridoma culture supernatant. Detects human IFN-alpha/beta R1 in direct ELISAs and Western blots. In direct ELISAs, does not cross-react with recombinant human (rh) IFN-gamma R1, rhIFN-gamma R2, recombinant mouse IFN-alpha/beta R2, rhIL-10 R beta , rhIL-10 R alpha , or rhIL-20 R beta .
- Reactivity
- Human
- Host
- Mouse
- Antigen sequence
AAA52730- Isotype
- IgG
- Antibody clone number
- 85228
- Vial size
- 100 Tests
- Storage
- Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied.
Submitted references Safe and Effective Treatment of Experimental Neuroblastoma and Glioblastoma Using Systemically Delivered Triple MicroRNA-Detargeted Oncolytic Semliki Forest Virus.
Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL).
Enhancement of cell type specificity by quantitative modulation of a chimeric ligand.
Ramachandran M, Yu D, Dyczynski M, Baskaran S, Zhang L, Lulla A, Lulla V, Saul S, Nelander S, Dimberg A, Merits A, Leja-Jarblad J, Essand M
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Mar 15;23(6):1519-1530
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Mar 15;23(6):1519-1530
Type I interferon (IFN-alpha/beta) rescues B-lymphocytes from apoptosis via PI3Kdelta/Akt, Rho-A, NFkappaB and Bcl-2/Bcl(XL).
Badr G, Saad H, Waly H, Hassan K, Abdel-Tawab H, Alhazza IM, Ahmed EA
Cellular immunology 2010;263(1):31-40
Cellular immunology 2010;263(1):31-40
Enhancement of cell type specificity by quantitative modulation of a chimeric ligand.
Cironi P, Swinburne IA, Silver PA
The Journal of biological chemistry 2008 Mar 28;283(13):8469-76
The Journal of biological chemistry 2008 Mar 28;283(13):8469-76
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Supportive validation
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- R&D Systems (provider)
- Main image
- Experimental details
- Detection of IFN-alpha/beta R1 in U937 Human cell line by Flow Cytometry. U937 human histiocytic lymphoma cell line was stained with Mouse Anti-Human IFN-alpha/beta R1 PE-conjugated Monoclonal Antibody (Catalog # FAB245P, filled histogram) or isotype control antibody (Catalog # IC002P, open histogram). View our protocol for Staining Membrane-associated Proteins.
