Explore
Validate
Learn
Western blot
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- NBP1-45243 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-45243, RRID:AB_10008794
- Product name
- Goat Polyclonal UBR2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse
- Host
- Goat
- Antigen sequence
SCPKSGGDKSRAPT- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references p300 Mediates Muscle Wasting in Lewis Lung Carcinoma.
p38β MAPK mediates ULK1-dependent induction of autophagy in skeletal muscle of tumor-bearing mice.
Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90.
Toll-like receptor 4 mediates Lewis lung carcinoma-induced muscle wasting via coordinate activation of protein degradation pathways.
p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis.
Activin A induces skeletal muscle catabolism via p38β mitogen-activated protein kinase.
Signaling mechanism of tumor cell-induced up-regulation of E3 ubiquitin ligase UBR2.
Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome).
Sin TK, Zhu JZ, Zhang G, Li YP
Cancer research 2019 Apr 1;79(7):1331-1342
Cancer research 2019 Apr 1;79(7):1331-1342
p38β MAPK mediates ULK1-dependent induction of autophagy in skeletal muscle of tumor-bearing mice.
Liu Z, Sin KWT, Ding H, Doan HA, Gao S, Miao H, Wei Y, Wang Y, Zhang G, Li YP
Cell stress 2018 Oct 10;2(11):311-324
Cell stress 2018 Oct 10;2(11):311-324
Tumor induces muscle wasting in mice through releasing extracellular Hsp70 and Hsp90.
Zhang G, Liu Z, Ding H, Zhou Y, Doan HA, Sin KWT, Zhu ZJ, Flores R, Wen Y, Gong X, Liu Q, Li YP
Nature communications 2017 Sep 19;8(1):589
Nature communications 2017 Sep 19;8(1):589
Toll-like receptor 4 mediates Lewis lung carcinoma-induced muscle wasting via coordinate activation of protein degradation pathways.
Zhang G, Liu Z, Ding H, Miao H, Garcia JM, Li YP
Scientific reports 2017 May 23;7(1):2273
Scientific reports 2017 May 23;7(1):2273
p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis.
Cha-Molstad H, Yu JE, Feng Z, Lee SH, Kim JG, Yang P, Han B, Sung KW, Yoo YD, Hwang J, McGuire T, Shim SM, Song HD, Ganipisetti S, Wang N, Jang JM, Lee MJ, Kim SJ, Lee KH, Hong JT, Ciechanover A, Mook-Jung I, Kim KP, Xie XQ, Kwon YT, Kim BY
Nature communications 2017 Jul 24;8(1):102
Nature communications 2017 Jul 24;8(1):102
Activin A induces skeletal muscle catabolism via p38β mitogen-activated protein kinase.
Ding H, Zhang G, Sin KW, Liu Z, Lin RK, Li M, Li YP
Journal of cachexia, sarcopenia and muscle 2017 Apr;8(2):202-212
Journal of cachexia, sarcopenia and muscle 2017 Apr;8(2):202-212
Signaling mechanism of tumor cell-induced up-regulation of E3 ubiquitin ligase UBR2.
Zhang G, Lin RK, Kwon YT, Li YP
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Jul;27(7):2893-901
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2013 Jul;27(7):2893-901
Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome).
Zenker M, Mayerle J, Lerch MM, Tagariello A, Zerres K, Durie PR, Beier M, Hülskamp G, Guzman C, Rehder H, Beemer FA, Hamel B, Vanlieferinghen P, Gershoni-Baruch R, Vieira MW, Dumic M, Auslender R, Gil-da-Silva-Lopes VL, Steinlicht S, Rauh M, Shalev SA, Thiel C, Ekici AB, Winterpacht A, Kwon YT, Varshavsky A, Reis A
Nature genetics 2005 Dec;37(12):1345-50
Nature genetics 2005 Dec;37(12):1345-50
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: UBR2 Antibody [NBP1-45243] - Staining of paraffin embedded Human Cortex. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
