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- Antigen structure
- References [1073]
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- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 14395-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14395-1-AP, RRID:AB_2223009
- Product name
- smooth muscle actin antibody
- Antibody type
- Polyclonal
- Description
- smooth muscle actin antibody (Cat. #14395-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Hepatobiliary organoids differentiated from hiPSCs relieve cholestasis-induced liver fibrosis in nonhuman primates.
Combined Placental Mesenchymal Stem Cells with Guided Nanoparticles Effective Against Diabetic Nephropathy in Mouse Model.
Nanofabrications of Erythrocyte Membrane-Coated Telmisartan Delivery System Effective for Radiosensitivity of Tumor Cells in Mice Model.
RASSF4 Attenuates Metabolic Dysfunction-Associated Steatotic Liver Disease Progression via Hippo Signaling and Suppresses Hepatocarcinogenesis.
The Mechanism of Catalpol to Improve Oxidative Damage of Dermal Fibroblasts Based on Nrf2/HO-1 Signaling Pathway.
Claudin-2 Mediates the Proximal Tubular Epithelial Cell-Fibroblast Crosstalk via Paracrine CTGF.
Seed and Soil: Consensus Molecular Subgroups (CMS) and Tumor Microenvironment Features Between Primary Lesions and Metastases of Different Organ Sites in Colorectal Cancer.
Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity.
HIF2A mediates lineage transition to aggressive phenotype of cancer-associated fibroblasts in lung cancer brain metastasis.
Hypoxia macrophage-derived exosomal miR-26b-5p targeting PTEN promotes the development of keloids.
The clinical impact of macrophage polarity after Kasai portoenterostomy in biliary atresia.
Enhancing Fat Transplantation Efficiency in a Mouse Model through Pretreatment of Adipose-Derived Stem Cells with RIP3 Inhibitors.
Morroniside improves AngII-induced cardiac fibroblast proliferation, migration, and extracellular matrix deposition by blocking p38/JNK signaling pathway through the downregulation of KLF5.
Early growth response protein 2 promotes partial epithelial-mesenchymal transition by phosphorylating Smad3 during renal fibrosis.
Knockdown of programmed cell death factor 4 restores erectile function by attenuating apoptosis in rats with bilateral cavernous nerve crush injury.
Obstructive Sleep Apnea Syndrome Exacerbates NASH Progression via Selective Autophagy-Mediated Eepd1 Degradation.
Uremic Toxin Receptor AhR Facilitates Renal Senescence and Fibrosis via Suppressing Mitochondrial Biogenesis.
Insulin-transferrin-selenium promote formation of tissue-engineered vascular grafts in early stage of culture.
Toll-Like Receptor 9 Aggravates Pulmonary Fibrosis by Promoting NLRP3-Mediated Pyroptosis of Alveolar Epithelial Cells.
Target NF-κB p65 for preventing posttraumatic joint contracture in rats.
Neutrophil-Mediated Nanozyme Delivery System for Acute Kidney Injury Therapy.
Transcriptomic analysis reveals the critical role of chemokine signaling in the anti-atherosclerosis effect of Xuefu Zhuyu decoction.
Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis.
Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
Dihydrocapsaicin suppresses the STING-mediated accumulation of ROS and NLRP3 inflammasome and alleviates apoptosis after ischemia-reperfusion injury of perforator skin flap.
Lacosamide alleviates bilateral cavernous nerve injury-induced erectile dysfunction in the rat model by ameliorating pathological changes in the corpus cavernosum.
Sirt7/HIC1 complex participates in hyperglycaemia-mediated EndMT via modulation of SDC1 expression in diabetic kidney disease and metabolic memory.
Dexamethasone promotes renal fibrosis by upregulating ILT4 expression in myeloid-derived suppressor cells.
Inhibition of STAT3 by S3I-201 suppress peritoneal fibroblast phenotype conversion and alleviate peritoneal fibrosis.
CNPY2 governs PDGF‑BB‑treated vascular smooth muscle cell proliferation, migration and phenotypic transformation via the Akt/mTOR/GSK‑3β signaling pathway.
Riboflavin protects against pancreatic cancer metastasis by targeting TGF-β receptor 1.
Paris polyphylla ethanol extract and polyphyllin I ameliorate adenomyosis by inhibiting epithelial-mesenchymal transition.
Midkine promotes renal fibrosis by stabilizing C/EBPβ to facilitate endothelial-mesenchymal transition.
Effects of Nanoparticle-Mediated Dihydromyricetin to Diabetic Wounds: An In Vivo Study.
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.
Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway.
CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis.
Podocyte-Specific Deletion of MCP-1 Fails to Protect against Angiotensin II- or Adriamycin-Induced Glomerular Disease.
Design, Synthesis, and Evaluation of Dihydropyrimidine Derivatives as Selective PDE1 Inhibitors for the Treatment of Liver Fibrosis.
Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids.
Enhanced Vascular-like Network Formation of Encapsulated HUVECs and ADSCs Coculture in Growth Factors Conjugated GelMA Hydrogels.
Withanolides from the active extract of Physalis angulate and their anti-hepatic fibrosis effects.
The SP1/SIRT1/ACLY signaling axis mediates fatty acid oxidation in renal ischemia-reperfusion-induced renal fibrosis.
SIRT1 activation ameliorates rhesus monkey liver fibrosis by inhibiting the TGF-β/smad signaling pathway.
Echinacoside Exerts Antihepatic Fibrosis Effects in High-Fat Mice Model by Modulating the ACVR2A-Smad Pathway.
Multi-omic profiling of clear cell renal cell carcinoma identifies metabolic reprogramming associated with disease progression.
MitoQ Alleviated PM(2.5) Induced Pulmonary Epithelial Cells Injury by Inhibiting Mitochondrial-Mediated Apoptosis.
Crocin Inhibits Orbital Fibroblasts Fibrosis in Thyroid-Associated Ophthalmopathy.
TRIM65 promotes vascular smooth muscle cell phenotypic transformation by activating PI3K/Akt/mTOR signaling during atherogenesis.
Knockdown of ARHGAP24 reduces intimal hyperplasia through inhibiting the proliferation and phenotypic switching of smooth muscle cells possibly by inactivating both AKT and ERK1/2 signaling pathways.
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Arctium lappa L. polysaccharides enhanced the therapeutic effects of nasal ectomesenchymal stem cells against liver fibrosis by inhibiting the Wnt/β-catenin pathway.
Primary cilia are critical for tracheoesophageal septation.
Machine learning and single-cell transcriptome profiling reveal regulation of fibroblast activation through THBS2/TGFβ1/P-Smad2/3 signalling pathway in hypertrophic scar.
Natural intestinal metabolite xylitol reduces BRD4 levels to mitigate renal fibrosis.
Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene.
Bacterial Cellulose-Based Bandages with Integrated Antibacteria and Electrical Stimulation for Advanced Wound Management.
Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition.
Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment.
Spinosin inhibits activated hepatic stellate cell to attenuate liver fibrosis by targeting Nur77/ASK1/p38 MAPK signaling pathway.
Augmentation of scleral glycolysis promotes myopia through histone lactylation.
Early-life ruminal microbiome-derived indole-3-carboxaldehyde and prostaglandin D2 are effective promoters of rumen development.
Tryptanthrin promotes pressure ulcers healing in mice by inhibiting macrophage-mediated inflammation via cGAS/STING pathways.
Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway.
Integrating Network Pharmacology and In Vitro Experimental Verification Revealing Bushenhuoxue Recipe Against Intrauterine Adhesions via PI3K-AKT Signaling Pathway.
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.
Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter.
Nitric oxide nano-reactor DNMF/PLGA enables tumor vascular microenvironment and chemo-hyperthermia synergetic therapy.
Bicyclol alleviates obesity-induced renal injury by inhibiting JNK and NF-κB-mediated inflammation.
Generation of a human induced pluripotent stem cell line harboring heteroplasmic m.3243A > G mutation in MT-TL1 gene.
Bioresponsive nanocomplex integrating cancer-associated fibroblast deactivation and immunogenic chemotherapy for rebuilding immune-excluded tumors.
A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction.
Stiffened tumor microenvironment enhances perineural invasion in breast cancer via integrin signaling.
TRPC6 Knockout Alleviates Renal Fibrosis through PI3K/AKT/GSK3B Pathway.
Dihydromyricetin alleviates inflammatory bowel disease associated intestinal fibrosis by inducing autophagy through the PI3K/AKT/mTOR signaling pathway.
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation.
Hsa_circ_0004214 involved in the epithelial-mesenchymal transition induced by beryllium sulfate through modulating JAK-STAT signaling pathway.
microRNA-125b-1-3p mediates autophagy via the RRAGD/mTOR/ULK1 signaling pathway and mitigates atherosclerosis progression.
Bioactive compound schaftoside from Clinacanthus nutans attenuates acute liver injury by inhibiting ferroptosis through activation the Nrf2/GPX4 pathway.
Multiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis.
Single-cell transcriptome profiling highlights the importance of telocyte, kallikrein genes, and alternative splicing in mouse testes aging.
Improved Cell Adhesion on Self-Assembled Chiral Nematic Cellulose Nanocrystal Films.
Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast crosstalk and induces the development of oral submucosal fibrosis.
Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis.
Graphene Far-Infrared Irradiation Can Effectively Relieve the Blood Pressure Level of Rat Untr-HT in Primary Hypertension.
Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research.
Resistance exercise upregulates Irisin expression and suppresses myocardial fibrosis following myocardial infarction via activating AMPK-Sirt1 and inactivating TGFβ1-Smad2/3.
The dual role of 20(S)-protopanaxadiol in alleviating pulmonary fibrosis through the gut-lung axis.
Repair potential of self-assembling peptide hydrogel in a mouse model of anterior cruciate ligament reconstruction.
Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos.
Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice.
Puerarin enhances TFEB-mediated autophagy and attenuates ROS-induced pyroptosis after ischemic injury of random-pattern skin flaps.
Loss of STARD13 contributes to aggressive phenotype transformation and poor prognosis in papillary thyroid carcinoma.
Uric acid promotes interleukin-17 expression to cause kidney injury.
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
Chitosan-based oral nanoparticles as an efficient platform for kidney-targeted drug delivery in the treatment of renal fibrosis.
A hyaluronic acid / chitosan composite functionalized hydrogel based on enzyme-catalyzed and Schiff base reaction for promoting wound healing.
Overexpression of Corin Ameliorates Kidney Fibrosis through Inhibition of Wnt/β-Catenin Signaling in Mice.
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Inhibition of TGFβ1 activation prevents radiation-induced lung fibrosis.
Quantitative Analysis of the Concentration of Trifluridine in Tumor Hypoxic Regions Using a Novel Platform Combining Functional Endoscopy and Mass Spectrometry.
Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway.
Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation.
Menstrual blood-derived stem cells exosomal miR-let-7 to ameliorate pulmonary fibrosis through inhibiting ferroptosis by Sp3/HDAC2/Nrf2 signaling pathway.
Lactate accumulation induced by Akt2-PDK1 signaling promotes pulmonary fibrosis.
MicroRNA miR-181d-5p regulates the MAPK signaling pathway by targeting mitogen-activated protein kinase 8 (MAPK8) to improve lupus nephritis.
The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro.
Phthalides from the rhizome of Ligusticum chuanxiong Hort. attenuate diabetic nephropathy in mice.
Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway.
Self-assembled coating with a metal-polyphenolic network for intraocular lens modification to prevent posterior capsule opacification.
The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin.
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple ameliorates renal interstitial fibrosis in CKD rats by inhibiting the TGF-β1/MAPK signaling pathway.
Network pharmacology, molecular docking and experimental verification of the mechanism of huangqi-jixuecao herb pair in treatment of peritoneal fibrosis.
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Claudin-18.2 mediated interaction of gastric Cancer cells and Cancer-associated fibroblasts drives tumor progression.
Hydrogen sulfide attenuates atherosclerosis induced by low shear stress by sulfhydrylating endothelium NFIL3 to restrain MEST mediated endothelial mesenchymal transformation.
Oncostatin M/Oncostatin M Receptor Signal Induces Radiation-Induced Heart Fibrosis by Regulating SMAD4 in Fibroblast.
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions.
Costunolide attenuates high-fat diet-induced inflammation and oxidative stress in non-alcoholic fatty liver disease.
IRF4 Participates in Pulmonary Fibrosis Induced by Silica Particles through Regulating Macrophage Polarization and Fibroblast Activation.
hPMSCs Regulate the Level of TNF-α and IL-10 in Th1 Cells and Improve Hepatic Injury in a GVHD Mouse Model via CD73/ADO/Fyn/Nrf2 Axis.
Microplastics cause hepatotoxicity in diabetic mice by disrupting glucolipid metabolism via PP2A/AMPK/HNF4A and promoting fibrosis via the Wnt/β-catenin pathway.
An Injectable Composite Hydrogel of Verteporfin-Bonded Carboxymethyl Chitosan and Oxidized Sodium Alginate Facilitates Scarless Full-Thickness Skin Regeneration.
Transcription factor c-Maf drives macrophages to promote hypertrophic scar formation.
BRG1 enhances porcine iPSC pluripotency through WNT/β-catenin and autophagy pathways.
Alleviative Effect of Lactoferrin Interventions Against the Hepatotoxicity Induced by Titanium Dioxide Nanoparticles.
Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition.
Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents.
Discovery of PRDM16-Mediated TRPA1 Induction as the Mechanism for Low Tubulo-Interstitial Fibrosis in Diabetic Kidney Disease.
Wearable bioadhesive ultrasound shear wave elastography.
The Upregulation of Leucine-Rich Repeat Containing 1 Expression Activates Hepatic Stellate Cells and Promotes Liver Fibrosis by Stabilizing Phosphorylated Smad2/3.
Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway.
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial-mesenchymal transition.
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
The mechanism of α2-macroglobulin against oxidative stress and promoting cell proliferation in intervertebral disc degeneration.
TGFβ2 mediates oxidative stress-induced epithelial-to-mesenchymal transition of bladder smooth muscle.
Lycorine relieves the CCl(4)-induced liver fibrosis mainly via the JAK2/STAT3 and PI3K/AKT signaling pathways.
Macroscopic and histological examination of human bridging veins.
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Cryptotanshinone alleviates liver fibrosis via inhibiting STAT3/CPT1A-dependent fatty acid oxidation in hepatic stellate cells.
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Generation of human induced pluripotent stem cell line from a patient with restrictive cardiomyopathy.
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Exosomes derived from bone marrow mesenchymal stem cells alleviate biliary ischemia reperfusion injury in fatty liver transplantation by inhibiting ferroptosis.
DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasis.
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
M2 macrophage-derived paracrine factor TNFSF13 affects the fibrogenic alterations in endothelial cells and cardiac fibroblasts by mediating the NF-κB and Akt pathway.
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Antler thymosin β10 reduces liver fibrosis via inhibiting TGF-β1/SMAD pathway.
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Antibiotic bone cement accelerates diabetic foot wound healing: Elucidating the role of ROCK1 protein expression.
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Icariin alleviates diabetic renal interstitial fibrosis aggravation by inhibiting miR-320a-3p targeting BMP6.
CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF-β1/Smad2/3 signaling in mouse viral myocarditis.
Low-Frequency Ultrasound Sensitive Piezo1 Channels Regulate Keloid-Related Characteristics of Fibroblasts.
PI3Kδ Mediates Fibrosis by Patient-Derived Vitreous.
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin.
Global proteomic analysis reveals lysine succinylation is involved in the pathogenesis of hypertrophic scar.
DEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis.
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
SirT7-mediated transcription of fascin in hyperglycemic glomerular endothelial cells contributes to EndMT in diabetic nephropathy.
Jin-Gui-Shen-Qi Wan alleviates fibrosis in mouse diabetic nephropathy via MHC class II.
Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway.
Baicalein alleviates intrahepatic cholestasis by regulating bile acid metabolism via an FXR-dependent manner.
NLRP3 inflammasome-mediated premature immunosenescence drives diabetic vascular aging dependent on the induction of perivascular adipose tissue dysfunction.
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Alleviate Hypoxia-Induced Pulmonary Arterial Hypertension in Mice Via Macrophages.
Improving impact of heparan sulfate on the endothelial glycocalyx abnormalities in atherosclerosis as revealed by glycan-protein interactome.
Incorporating machine learning and PPI networks to identify mitochondrial fission-related immune markers in abdominal aortic aneurysms.
FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation.
Patient-Derived Exosomes as siRNA Carriers in Ovarian Cancer Treatment.
Liquiritigenin Attenuated Collagen-Induced Arthritis and Cardiac Complication via Inflammation and Fibrosis Inhibition in Mice.
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
Indirubin alleviates CCl(4)-induced liver fibrosis by regulation of TGF-β-mediated signaling pathways.
Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages.
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts.
FAT10 Silencing Prevents Liver Fibrosis through Regulating SIRT1 Expression in Hepatic Stellate Cells.
Sarcoma protein kinase inhibition alleviates liver fibrosis by promoting hepatic stellate cells ferroptosis.
Adiponectin inhibits TGF-β1-induced skin fibroblast proliferation and phenotype transformation via the p38 MAPK signaling pathway.
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.
Identification and Characterization of a Novel Nanobody Against Human CTGF to Reveal Its Antifibrotic Effect in an in vitro Model of Liver Fibrosis.
Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis.
Co-Delivery Nanomicelles for Potentiating TNBC Immunotherapy by Synergetically Reshaping CAFs-Mediated Tumor Stroma and Reprogramming Immunosuppressive Microenvironment.
Irisin Ameliorates Renal Tubulointerstitial Fibrosis by Regulating the Smad4/β-Catenin Pathway in Diabetic Mice.
GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation.
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery.
A comprehensive cuproptosis score and associated gene signatures reveal prognostic and immunological features of idiopathic pulmonary fibrosis.
Four novel mutations identification in 17 beta-hydroxysteroid dehydrogenase-3 deficiency and our clinical experience: possible benefits of early treatment.
Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway.
The influence of angiopoietin-like protein 3 on macrophages polarization and its effect on the podocyte EMT in diabetic nephropathy.
APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN.
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation.
IL-12α deficiency attenuates pressure overload-induced cardiac inflammation, hypertrophy, dysfunction, and heart failure progression.
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.
Primary extra-gastrointestinal stromal tumor of retroperitoneum: Clinicopathologic characteristics and prognosis of six cases.
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ketogenic diet alleviates renal fibrosis in mice by enhancing fatty acid oxidation through the free fatty acid receptor 3 pathway.
Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model.
Integrative analysis of cancer-associated fibroblast signature in gastric cancer.
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
A novel onco-cardiological mouse model of lung cancer-induced cardiac dysfunction and its application in identifying potential roles of tRNA-derived small RNAs.
miR-32-5p induces hepatic steatosis and hyperlipidemia by triggering de novo lipogenesis.
SGLT2 inhibitor empagliflozin downregulates miRNA-34a-5p and targets GREM2 to inactivate hepatic stellate cells and ameliorate non-alcoholic fatty liver disease-associated fibrosis.
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Celastrol attenuates diabetic nephropathy by upregulating SIRT1-mediated inhibition of EZH2related wnt/β-catenin signaling.
Axitinib attenuates the progression of liver fibrosis by restoring mitochondrial function.
Geniposide alleviated bile acid-associated NLRP3 inflammasome activation by regulating SIRT1/FXR signaling in bile duct ligation-induced liver fibrosis.
Mammalian cleavage factor 25 targets KLF14 to inhibit hepatic stellate cell activation and liver fibrosis.
HMGA2 knockdown alleviates the progression of nonalcoholic fatty liver disease (NAFLD) by downregulating SNAI2 expression.
TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1.
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
Exosomal miR-17-5p from human embryonic stem cells prevents pulmonary fibrosis by targeting thrombospondin-2.
The effects of Shikonin on the hypertrophic scar of rabbit ears via the TLR4/NF-κB signaling pathway.
Curcumin ameliorates focal segmental glomerulosclerosis by inhibiting apoptosis and oxidative stress in podocytes.
Dendrobium officinale Kimura & Migo polysaccharide inhibits hyperglycaemia-induced kidney fibrosis via the miRNA-34a-5p/SIRT1 signalling pathway.
The alcohol extracts of Sceptridium ternatum (Thunb.) Lyon exert anti-pulmonary fibrosis effect through targeting SETDB1/STAT3/p-STAT3 signaling.
The effect of GelDex-S58 hydrogel on anti-conjunctival scarring after glaucoma filtration surgery.
Selective inhibition of glycolysis in hepatic stellate cells and suppression of liver fibrogenesis with vitamin A-derivative decorated camptothecin micelles.
PRDX1 Cys52Ser variant alleviates nonalcoholic steatohepatitis by reducing inflammation in mice.
Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis.
PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression.
Human-Induced Hepatocytes-Derived Extracellular Vesicles Ameliorated Liver Fibrosis in Mice Via Suppression of TGF-β1/Smad Signaling and Activation of Nrf2/HO-1 Signaling.
Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway.
Myeloid-specific deletion of Capns1 attenuates myocardial infarction injury via restoring mitochondrial function and inhibiting inflammasome activation.
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats.
Nintedanib inhibits normal human vitreous-induced epithelial-mesenchymal transition in human retinal pigment epithelial cells.
Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder.
Farnesoid X receptor activation is required for the anti-inflammatory and anti-oxidative stress effects of Alisol B 23-acetate in carbon tetrachloride-induced liver fibrosis in mice.
Hierarchically Released Liquid Metal Nanoparticles for Mild Photothermal Therapy/Chemotherapy of Breast Cancer Bone Metastases via Remodeling Tumor Stromal Microenvironment.
Sox7-positive endothelial progenitors establish coronary arteries and govern ventricular compaction.
Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling.
Fu-Zheng-Tong-Luo formula promotes autophagy and alleviates idiopathic pulmonary fibrosis by controlling the Janus kinase 2/signal transducer and activator of transcription 3 pathway.
NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis.
CRTC2 activates the epithelial-mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway.
Sodium-glucose cotransporter 2 inhibitor canagliflozin alleviates vascular calcification through suppression of nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 inflammasome.
Activation of acetyl-CoA synthetase 2 mediates kidney injury in diabetic nephropathy.
The Dual-Mode Transition of Myofibroblasts Derived from Hepatic Stellate Cells in Liver Fibrosis.
Targeting ferroptosis attenuates podocytes injury and delays tubulointerstitial fibrosis in focal segmental glomerulosclerosis.
Single-cell transcriptome profiling reveals immune and stromal cell heterogeneity in primary Sjögren's syndrome.
Minichromosome maintenance 6 protects against renal fibrogenesis by regulating DUSP6-mediated ERK/GSK-3β/Snail1 signaling.
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
High glucose promotes benign prostatic hyperplasia by downregulating PDK4 expression.
Vitamin D(3) analogue calcipotriol inhibits the profibrotic effects of transforming growth factor- β1 on pancreatic stellate cells.
Colchicine protects against the development of experimental abdominal aortic aneurysm.
20(R)-ginsenoside Rg3-loaded polyurethane/marine polysaccharide based nanofiber dressings improved burn wound healing potentials.
Structural analysis and attenuates hyperuricemic nephropathy of dextran from the Imperata cylindrica Beauv. var. major (Nees) C. E. Hubb.
Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition.
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Single-cell analysis reveals immune cellular components in odontogenic keratocysts.
Macrophage-derived inflammation promotes pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension mice.
Unleashing the healing potential: Exploring next-generation regenerative protein nanoscaffolds for burn wound recovery.
Butyrate alleviates renal fibrosis in CKD by regulating NLRP3-mediated pyroptosis via the STING/NF-κB/p65 pathway.
3D Prestress Bioprinting of Directed Tissues.
Silk Acid as an Implantable Biomaterial for Tissue Regeneration.
Caveolin-1 is critical for hepatic iron storage capacity in the development of nonalcoholic fatty liver disease.
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.
Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling.
Precisely Regulating M2 Subtype Macrophages for Renal Fibrosis Resolution.
Four-dimensional hydrogel dressing adaptable to the urethral microenvironment for scarless urethral reconstruction.
RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment.
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Exosomes derived from cardiac fibroblasts with angiotensin II stimulation provoke hypertrophy and autophagy inhibition in cardiomyocytes.
Agathis dammara Extract and its Monomer Araucarone Attenuate Abdominal Aortic Aneurysm in Mice.
MircroRNA-92b as a negative regulator of the TGF-β signaling by targeting the type I receptor.
A role of TRIM59 in pulmonary hypertension: modulating the protein ubiquitylation modification.
Gracillin relieves pulmonary fibrosis by suppressing the STAT3 axis.
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression.
Electroacupuncture alleviates intrauterine adhesion through regulating autophagy in rats.
cGAS-STING signaling pathway promotes hypoxia-induced renal fibrosis by regulating PFKFB3-mediated glycolysis.
Folic acid supplementation rescues bladder injury in fetal rats with myelomeningocele.
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction.
Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR‑29b‑3p.
Prolonged exposure to the herbicide atrazine promotes kidney fibrosis by activating Wnt/β-catenin signaling in rats.
Liver sinusoidal endothelial S1pr2 regulates experimental liver fibrosis through YAP/TGF-β signaling pathway.
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization.
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
A multifunctional neuromodulation platform utilizing Schwann cell-derived exosomes orchestrates bone microenvironment via immunomodulation, angiogenesis and osteogenesis.
Inhibitory effect of miR-138-5p on choroidal fibrosis in lens-induced myopia guinea pigs via suppressing the HIF-1α signaling pathway.
Nintedanib prevents TGF-β2-induced epithelial-mesenchymal transition in retinal pigment epithelial cells.
Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation.
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.
EPAS1 prevents telomeric damage-induced senescence by enhancing transcription of TRF1, TRF2, and RAD50.
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure.
Aristolocholic acid I promotes renal tubular epithelial fibrosis by upregulating matrix metalloproteinase-9 expression via activating the C3a/C3aR axis of macrophages.
Development and validation of a radiomics model of magnetic resonance for predicting liver metastasis in resectable pancreatic ductal adenocarcinoma patients.
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Noncanonical atherosclerosis as the driving force in tricuspid aortic valve associated aneurysms - A trace collection.
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II.
ZD6474 Attenuates Fibrosis and Inhibits Neovascularization in Human Pterygium by Suppressing AKT-mTOR Signaling Pathway.
m(6)A methylation-induced NR1D1 ablation disrupts the HSC circadian clock and promotes hepatic fibrosis.
CCN2/CTGF promotes liver fibrosis through crosstalk with the Slit2/Robo signaling.
Deletion of LCMR1 in alveolar type II cells induces lethal impairment of lung structure and function in adult mice.
Curcumol suppresses endothelial-to-mesenchymal transition via inhibiting the AKT/GSK3β signaling pathway and alleviates pulmonary arterial hypertension in rats.
Benzylisoquinoline alkaloids inhibit lung fibroblast activation mainly via inhibiting TGF-β1/Smads and ERK1/2 pathway proteins.
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.
Collagen Triple Helix Repeat Containing 1 Deficiency Protects Against Airway Remodeling and Inflammation in Asthma Models In Vivo and In Vitro.
Efficacy of Danggui Buxue decoction on diabetic nephropathy-induced renal fibrosis in rats and possible mechanism.
A novel tetra-PEG based hydrogel for prevention of esophageal stricture after ESD in a porcine model.
Protective effects of methylprednisolone-cyclophosphamide treatment on bleomycin-induced pulmonary fibrosis.
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Differences in p38-STAT3-S100A11 signaling after the administration of aristolochic acid I and IVa may account for the disparity in their nephrotoxicity.
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
Silencing of NOTCH3 Signaling in Meniscus Smooth Muscle Cells Inhibits Fibrosis and Exacerbates Degeneration in a HEYL-Dependent Manner.
Time-dependent effect of REV-ERBα agonist SR9009 on nonalcoholic steatohepatitis and gut microbiota in mice.
MgIG Attenuates Oxaliplatin-induced Hepatotoxicity through Suppression of Connexin 43 in Hepatic Stellate Cells.
Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration.
Identification of potential biomarkers for idiopathic pulmonary fibrosis and validation of TDO2 as a potential therapeutic target.
Autophagy-Interfering Nanoboat Drifting along CD44-Golgi-ER Flow as RNAi Therapeutics for Hepatic Fibrosis.
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion.
HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo.
Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis.
Scarless wound healing programmed by core-shell microneedles.
Ferroptosis in the Lacrimal Gland Is Involved in Dry Eye Syndrome Induced by Corneal Nerve Severing.
Venoarterial extracorporeal membrane oxygenation improves survival in a rat model of acute myocardial infarction.
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.
Total flavonoid extract from Dracocephalum moldavica L. improves pulmonary fibrosis by reducing inflammation and inhibiting the hedgehog signaling pathway.
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Step-wise CAG@PLys@PDA-Cu(2+) modification on micropatterned nanofibers for programmed endothelial healing.
Inhibiting Heat Shock Protein 90 Attenuates Nucleus Pulposus Fibrosis and Pathologic Angiogenesis Induced by Macrophages via Down-Regulating Cell Migration-Inducing Protein.
Inhaled Lipid Nanoparticles Alleviate Established Pulmonary Fibrosis.
Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.
Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL-6 pathway in renal tubular epithelial cells.
CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
Anticoagulants Enhance Molecular and Cellular Immunotherapy of Cancer by Improving Tumor Microcirculation Structure and Function and Redistributing Tumor Infiltrates.
Metformin attenuates chronic lung allograft dysfunction: evidence in rat models.
Disruption of RCAN1.4 expression mediated by YY1/HDAC2 modulates chronic renal allograft interstitial fibrosis.
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design.
CXCL17 Attenuates Diesel Exhaust Emissions Exposure-Induced Lung Damage by Regulating Macrophage Function.
Metformin suppressed tendon injury-induced adhesion via hydrogel-nanoparticle sustained-release system.
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
Nanoengineered mesenchymal stem cell therapy for pulmonary fibrosis in young and aged mice.
Atractylenolide III Ameliorates Bile Duct Ligation-Induced Liver Fibrosis by Inhibiting the PI3K/AKT Pathway and Regulating Glutamine Metabolism.
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Elevated retinal fibrosis in experimental myopia is involved in the activation of the PI3K/AKT/ERK signaling pathway.
Single-cell RNA sequencing reveals that HSD17B2 in cancer-associated fibroblasts promotes the development and progression of castration-resistant prostate cancer.
Ginsenoside Rg3 liposomes regulate tumor microenvironment for the treatment of triple negative breast cancer.
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Quercetin inhibits the amphiregulin/EGFR signaling-mediated renal tubular epithelial-mesenchymal transition and renal fibrosis in obstructive nephropathy.
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
Spinal Cord Stimulation Attenuates Neural Remodeling, Inflammation, and Fibrosis After Myocardial Infarction.
Qing Fei Hua Xian Decoction ameliorates bleomycin-induced pulmonary fibrosis by suppressing oxidative stress through balancing ACE-AngII-AT1R/ACE2-Ang-(1-7)-Mas axis.
PD-L1 upregulation promotes drug-induced pulmonary fibrosis by inhibiting vimentin degradation.
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
The effects of taraxasterol on liver fibrosis revealed by RNA sequencing.
Effective-compounds of Jinshui Huanxian formula ameliorates fibroblast activation in pulmonary fibrosis by inhibiting the activation of mTOR signaling.
Yishen-Qingli-Huoxue formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling.
Elevated Angiotensin-II Levels Contribute to the Pathogenesis of Open-Angle Glaucoma Via Inducing the Expression of Fibrosis-Related Genes in Trabecular Meshwork Cells Through a ROS/NOX4/SMAD3 Axis.
N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells.
Neuron-Glial Antigen 2 Participates in Liver Fibrosis via Regulating the Differentiation of Bone Marrow Mesenchymal Stem Cell to Myofibroblast.
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Baicalin prevents fibrosis of human trabecular meshwork cells via inhibiting the MyD88/NF-κB pathway.
Facile preparation of a novel nanoemulsion based hyaluronic acid hydrogel loading with Poria cocos triterpenoids extract for wound dressing.
Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca2+ mishandling and atrial fibrosis in active immunization rabbit models.
Biejiajian pill inhibits progression of hepatocellular carcinoma by downregulating PDGFRβ signaling in cancer-associated fibroblasts.
Exosomes derived from human adipose mesenchymal stem cells ameliorate hepatic fibrosis by inhibiting PI3K/Akt/mTOR pathway and remodeling choline metabolism.
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory/anti-fibrotic therapy of inflammatory bowel disease.
HDAC7/c-Myc signaling pathway promotes the proliferation and metastasis of choroidal melanoma cells.
Endosulfan induced kidney cell injury by modulating ACE2 through up-regulating miR-429 in HK-2 cells.
20-Hydroxytetraenoic acid induces hepatic fibrosis via the TGF-β1/Smad3 signaling pathway.
The m6A demethylase FTO promotes keloid formation by up-regulating COL1A1.
Cell-Permeable PROTAC Degraders against KEAP1 Efficiently Suppress Hepatic Stellate Cell Activation through the Antioxidant and Anti-Inflammatory Pathway.
Endoscopy Deliverable and Mushroom-Cap-Inspired Hyperboloid-Shaped Drug-Laden Bioadhesive Hydrogel for Stomach Perforation Repair.
Macrophage-derived exosomal lncRNA MSTRG.91634.7 inhibits fibroblasts activation by targeting PINK1 in silica-induced lung fibrosis.
VX-765 attenuates silica-induced lung inflammatory injury and fibrosis by modulating alveolar macrophages pyroptosis in mice.
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling.
Generation of an induced pluripotent stem cell line (IPCASi001-A) from an autism spectrum disorder individual without intellectual disability.
Deposition of platelet-derived microparticles in podocytes contributes to diabetic nephropathy.
Glycyrrhizic acid improves tacrolimus-induced renal injury by regulating autophagy.
In Situ Endothelialization of Free-Form 3D Network of Interconnected Tubular Channels via Interfacial Coacervation by Aqueous-in-Aqueous Embedded Bioprinting.
miRNA‑92a inhibits vascular smooth muscle cell phenotypic modulation and may help prevent in‑stent restenosis.
Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.
Fc Fragment of IgE Receptor Ig (FCER1G) acts as a key gene involved in cancer immune infiltration and tumour microenvironment.
A small-molecule JNK inhibitor JM-2 attenuates high-fat diet-induced non-alcoholic fatty liver disease in mice.
Hepatic stellate cell-released CXCL1 aggravates HCC malignant behaviors through the MIR4435-2HG/miR-506-3p/TGFB1 axis.
LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition in Human Kidney 2 Cells.
Prognostic Value of CXCL12 in Non-Small Cell Lung Cancer Patients Undergoing Tumor Resection.
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Macrophage-derived GPNMB trapped by fibrotic extracellular matrix promotes pulmonary fibrosis.
Aerobic exercise inhibits renal EMT by promoting irisin expression in SHR.
Nanodrug rescues liver fibrosis via synergistic therapy with H(2)O(2) depletion and Saikosaponin b1 sustained release.
Intermedin 1-53 Ameliorates Atrial Fibrosis and Reduces Inducibility of Atrial Fibrillation via TGF-β1/pSmad3 and Nox4 Pathway in a Rat Model of Heart Failure.
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
RGS1 mediates renal interstitial fibrosis through activation of the inflammatory response.
STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.
Evaluation of topical methylene blue nanoemulsion for wound healing in diabetic mice.
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway.
Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy.
Increased m6A-RNA methylation and demethylase FTO suppression is associated with silica-induced pulmonary inflammation and fibrosis.
KPNA2 Silencing, Regulated by E3 Ubiquitin Ligase FBXW7, Alleviates Endothelial Dysfunction and Inflammation Through Inhibiting the Nuclear Translocation of p65 and IRF3: A Possible Therapeutic Approach for Atherosclerosis.
Human umbilical cord mesenchymal stem cell exosomes alleviate acute kidney injury by inhibiting pyroptosis in rats and NRK-52E cells.
Exoskeleton Partial-Coated Stem Cells for Infarcted Myocardium Restoring.
Vitamin D3 alleviates lung fibrosis of type 2 diabetic rats via SIRT3 mediated suppression of pyroptosis.
Polydatin alleviates bleomycin-induced pulmonary fibrosis and alters the gut microbiota in a mouse model.
Engineered muscle from micro-channeled PEG scaffold with magnetic Fe(3)O(4) fixation towards accelerating esophageal muscle repair.
Polyethylene glycol crosslinked decellularized single liver lobe scaffolds with vascular endothelial growth factor promotes angiogenesis in vivo.
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
Triptolide attenuates CCL(4)-induced liver fibrosis by regulating the differentiation of CD(4)(+) T cells in mice.
BMAL1 inhibits renal fibrosis and renal interstitial inflammation by targeting the ERK1/2/ELK-1/Egr-1 axis.
Sodium alginate combined with oxymatrine ameliorates CCl(4)-induced chemical hepatic fibrosis in mice.
Tamoxifen induced cardiac damage via the IL-6/p-STAT3/PGC-1α pathway.
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Oleanolic acid derivative alleviates cardiac fibrosis through inhibiting PTP1B activity and regulating AMPK/TGF-β/Smads pathway.
Suppressive effect of nitric oxide synthase (NOS) inhibitor L-NMMA acetate on choroidal fibrosis in experimental myopic guinea pigs through the nitric oxide signaling pathway.
The Long non-coding RNA MALAT1 functions as a competing endogenous RNA to regulate vascular remodeling by sponging miR-145-5p/HK2 in hypertension.
Canagliflozin ameliorates hypobaric hypoxia-induced pulmonary arterial hypertension by inhibiting pulmonary arterial smooth muscle cell proliferation.
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Muscone inhibits angiotensin II-induced cardiac hypertrophy through the STAT3, MAPK and TGF-β/SMAD signaling pathways.
Exosomal ITGB6 from dormant lung adenocarcinoma cells activates cancer-associated fibroblasts by KLF10 positive feedback loop and the TGF-β pathway.
Biodegradable nano black phosphorus based SDF1-α delivery system ameliorates Erectile Dysfunction in a cavernous nerve injury rat model by recruiting endogenous stem/progenitor cells.
A multi-functional double cross-linked chitosan hydrogel with tunable mechanical and antibacterial properties for skin wound dressing.
Anti-VEGFR2 F(ab')(2) drug conjugate promotes renal accumulation and glomerular repair in diabetic nephropathy.
Hepatic Stellate Cell- and Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis.
The application of a novel platform of multiparametric magnetic resonance imaging in a bioenvironmental toxic carbon tetrachloride-induced mouse model of liver fibrosis.
Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein.
Ginsenoside Rg1 Alleviates Lipopolysaccharide-Induced Fibrosis of Endometrial Epithelial Cells in Dairy Cows by Inhibiting Reactive Oxygen Species-Activated NLRP3.
＜Editors' Choice＞ Supernatant from activated omentum accelerates wound healing in diabetic mice wound model.
Dipeptidase‑2 is a prognostic marker in lung adenocarcinoma that is correlated with its sensitivity to cisplatin.
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
Salvianolic Acid B Attenuates Hypertrophic Scar Formation In Vivo and In Vitro.
sST2: A Bridge Between Sirt1/p53/p21 Signal-Induced Senescence and TGF-β1/Smad2/3 Regulation of Cardiac Fibrosis in Mouse Viral Myocarditis.
Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs.
Kangfuxin Accelerates Extraction Socket Healing by Promoting Angiogenesis Via Upregulation of CCL2 in Stem Cells.
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Sustained release of magnesium and zinc ions synergistically accelerates wound healing.
Crosstalk between Interleukin-1 Receptor-Like 1 and Transforming Growth Factor-β Receptor Signaling Promotes Renal Fibrosis.
p53 deacetylation alleviates calcium oxalate deposition-induced renal fibrosis by inhibiting ferroptosis.
Ginsenoside Rg1 ameliorates hypoxia-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition and inflammation by regulating CCN1.
Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2-dependent mechanism.
Amelioratory effects of astragaloside IV on hepatocarcinogenesis via Nrf2-mediated pSmad3C/3L transformation.
Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer.
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
N-acetyltransferase 10 promotes cutaneous wound repair via the NF-κB-IL-6 axis.
Baricitinib improves pulmonary fibrosis in mice with rheumatoid arthritis-associated interstitial lung disease by inhibiting the Jak2/Stat3 signaling pathway.
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis.
Exosomal miR-103a-3p from Crohn's Creeping Fat-Derived Adipose-Derived Stem Cells Contributes to Intestinal Fibrosis by Targeting TGFBR3 and Activating Fibroblasts.
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling.
Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing.
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m6A-YTHDF2-dependent mechanism.
Effect of roflumilast on airway remodeling in asthmatic mice exposed to or not exposed to cigarette smoke: Comparison with the effect of dexamethasone.
MicroRNA-146a Promotes Embryonic Stem Cell Differentiation towards Vascular Smooth Muscle Cells through Regulation of Kruppel-like Factor 4.
Myocardin Reverses Hypoxia-Inducible Factor-1α Mediated Phenotypic Modulation of Corpus Cavernosum Smooth Muscle Cells in Hypoxia Induced by Cobalt Chloride.
Restoration of Sinusoid Fenestrae Followed by Targeted Nanoassembly Delivery of an Anti-Fibrotic Agent Improves Treatment Efficacy in Liver Fibrosis.
Biomimetic nanoparticles drive the mechanism understanding of shear-wave elasticity stiffness in triple negative breast cancers to predict clinical treatment.
Breach of tolerance versus burden of bile acids: Resolving the conundrum in the immunopathogenesis and natural history of primary biliary cholangitis.
A novel co-culture assay to evaluate the effects of sympathetic innervation on vascular smooth muscle differentiation.
Fate mapping RNA-sequencing reveal Malat1 regulates Sca1(+) progenitor cells to vascular smooth muscle cells transition in vascular remodeling.
Active ingredients screening and pharmacological mechanism research of curcumae rhizoma-sparganii rhizoma herb pair ameliorates liver fibrosis based on network pharmacology.
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
Continuous Monochromatic Blue Light Exacerbates High-Fat Diet-Induced Kidney Injury via Corticosterone-Mediated Oxidative Stress.
Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress.
Establishment of a Rat Model of Liver Venous Deprivation: Simultaneous Portal and Hepatic Vein Ligation.
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Jia-Wei-Si-Miao-Yong-An Fang stimulates the healing of acute radiation-induced cutaneous wounds through MAPK/ERK pathway.
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson-Gilford Progeria Syndrome.
Histone lactylation driven by mROS-mediated glycolytic shift promotes hypoxic pulmonary hypertension.
Brevilin A is a potent anti-metastatic CRC agent that targets the VEGF-IL6-STAT3 axis in the HSCs-CRC interplay.
GL-V9 ameliorates liver fibrosis by inhibiting TGF-β/smad pathway.
Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury.
Deciphering Key Foreign Body Reaction-Related Transcription Factors and Genes Through Transcriptome Analysis.
Establishment of a New Abdominal Aortic Aneurysm Model in Rats by a Retroperitoneal Approach.
Anti-fibrotic effect of extracellular vesicles derived from tea leaves in hepatic stellate cells and liver fibrosis mice.
Hepatoblastoma: Derived Exosomal LncRNA NEAT1 Induces BMSCs Differentiation into Tumor-Supporting Myofibroblasts via Modulating the miR-132/MMP9 Axis.
C/EBPα-Mediated Transcriptional Activation of PIK3C2A Regulates Autophagy, Matrix Metalloproteinase Expression, and Phenotypic of Vascular Smooth Muscle Cells in Aortic Dissection.
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress.
The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis.
Qufeng Xuanbi Formula Ameliorates Airway Remodeling in Asthmatic Mice by Suppressing Airway Smooth Muscle Cell Proliferation through MEK/ERK Signaling Pathway.
Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.
Blockade of SK4 channels suppresses atrial fibrillation by attenuating atrial fibrosis in canines with prolonged atrial pacing.
Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling.
Knockdown of CD146 promotes endothelial-to-mesenchymal transition via Wnt/β-catenin pathway.
The conditioned medium from mesenchymal stromal cells pretreated with proinflammatory cytokines promote fibroblasts migration and activation.
Exosome Derived from Mesenchymal Stem Cells Alleviates Pathological Scars by Inhibiting the Proliferation, Migration and Protein Expression of Fibroblasts via Delivering miR-138-5p to Target SIRT1.
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Regenerative Peripheral Nerve Interfaces Effectively Prevent Neuroma Formation After Sciatic Nerve Transection in Rats.
Metformin Ameliorates Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells in Diabetes by Increasing Vitamin D Receptor Expression.
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Heidihuangwan alleviates renal fibrosis in rats with 5/6 nephrectomy by inhibiting autophagy.
Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling.
Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis.
TIM-4 in macrophages contributes to nasal polyp formation through the TGF-β1-mediated epithelial to mesenchymal transition in nasal epithelial cells.
Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome.
Ganfule capsule alleviates bile duct ligation-induced liver fibrosis in mice by inhibiting glutamine metabolism.
Akkermansia muciniphila Alters Gut Microbiota and Immune System to Improve Cardiovascular Diseases in Murine Model.
Beneficial Effect of Edoxaban on Preventing Atrial Fibrillation and Coagulation by Reducing Inflammation via HBG1/HBD Biomarkers.
Mechanism of Endoplasmic Reticulum Stress Pathway in the Osteogenic Phenotypic Transformation of Aortic Valve Interstitial Cells.
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps.
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Long Noncoding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 in Extracellular Vesicles Promotes Hepatic Stellate Cell Activation, Liver Fibrosis and β-Catenin Signaling Pathway.
Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis.
Yao medicine Amydrium hainanense suppresses hepatic fibrosis by repressing hepatic stellate cell activation via STAT3 signaling.
Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway.
Norepinephrine acting on adventitial fibroblasts stimulates vascular smooth muscle cell proliferation via promoting small extracellular vesicle release.
Irradiation enhances the malignancy-promoting behaviors of cancer-associated fibroblasts.
Fibroblasts mediate the angiogenesis of pheochromocytoma by increasing COX4I2 expression.
Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis.
Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway.
From hair to liver: emerging application of hair follicle mesenchymal stem cell transplantation reverses liver cirrhosis by blocking the TGF-β/Smad signaling pathway to inhibit pathological HSC activation.
Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.
Asiaticoside Combined With Carbon Ion Implantation to Improve the Biocompatibility of Silicone Rubber and to Reduce the Risk of Capsule Contracture.
Macrophage derived miR-7219-3p-containing exosomes mediate fibroblast trans-differentiation by targeting SPRY1 in silicosis.
Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
Anti-angiogenic nano-delivery system promotes tumor vascular normalizing and micro-environment reprogramming in solid tumor.
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.
N-Acetyl-l-tryptophan inhibits CCl(4)-induced hepatic fibrogenesis via regulating TGF-β1/SMAD and Hippo/YAP1 signal.
Immunohistochemical analysis of PD-L1 and tumor-infiltrating immune cells expression in the tumor microenvironment of primary signet ring cell carcinoma of the prostate.
Metabonomics profile analysis in inflammation-induced preterm birth and the potential role of metabolites in regulating premature cervical ripening.
Alamandine alleviated heart failure and fibrosis in myocardial infarction mice.
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
Leucine Supplementation in Middle-Aged Male Mice Improved Aging-Induced Vascular Remodeling and Dysfunction via Activating the Sirt1-Foxo1 Axis.
Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis.
Studies of ultrastructure, gene expression, and marker analysis reveal that mouse bladder PDGFRA(+) interstitial cells are fibroblasts.
Sphingosine 1-phosphate receptor 2 promotes erythrocyte clearance by vascular smooth muscle cells in intraplaque hemorrhage through MFG-E8 production.
Salt-inducible kinase 1 deficiency promotes vascular remodeling in pulmonary arterial hypertension via enhancement of yes-associated protein-mediated proliferation.
Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
Activating α7nAChR ameliorates abdominal aortic aneurysm through inhibiting pyroptosis mediated by NLRP3 inflammasome.
UFMylation Is Activated in Atherosclerosis of ApoE Knockout Mice.
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
Induction of GLI1 by miR-27b-3p/FBXW7/KLF5 pathway contributes to pulmonary arterial hypertension.
Established new compound IMB16-4 self-emulsifying drug delivery systems for increasing oral bioavailability and enhancing anti-hepatic fibrosis effect.
CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment.
A network pharmacology-based study on the mechanism of astragaloside IV alleviating renal fibrosis through the AKT1/GSK-3β pathway.
Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization.
Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis.
Single-cell RNA-seq analysis of testicular somatic cell development in pigs.
Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
Biomimetic cell membrane-coated glucose/oxygen-exhausting nanoreactor for remodeling tumor microenvironment in targeted hypoxic tumor therapy.
Apigenin inhibits fibrous scar formation after acute spinal cord injury through TGFβ/SMADs signaling pathway.
Apatinib Through Activating the RhoA/ROCK Signaling Pathway to Cause Dysfunction of Vascular Smooth Muscle Cells.
Extracellular vesicles from human urine-derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration.
Aligned nanofibrous collagen membranes from fish swim bladder as a tough and acid-resistant suture for pH-regulated stomach perforation and tendon rupture.
Pirfenidone-loaded exosomes derived from pancreatic ductal adenocarcinoma cells alleviate fibrosis of premetastatic niches to inhibit liver metastasis.
The Impact of Sleep Disturbance on Gut Microbiota, Atrial Substrate, and Atrial Fibrillation Inducibility in Mice: A Multi-Omics Analysis.
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.
A Shape-Adaptive Gallic Acid Driven Multifunctional Adhesive Hydrogel Loaded with Scolopin2 for Wound Repair.
Ultrastructural Characterization of Human Gingival Fibroblasts in 3D Culture.
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis.
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Disulfiram ameliorates nonalcoholic steatohepatitis by modulating the gut microbiota and bile acid metabolism.
NLRC3 deficiency promotes cutaneous wound healing due to the inhibition of p53 signaling.
PEDF reduces malignant cells proliferation and inhibits the progression of myelofibrosis in myeloproliferative neoplasms.
Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells.
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Development and identification of a induced pluripotent stem cells line (SMBCi013-A) derived from urine cells of a patient with Wilson's disease.
Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway.
MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1.
P16ink4a overexpression ameliorates cardiac remodeling of mouse following myocardial infarction via CDK4/pRb pathway.
The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy.
Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model.
Exosomal let-7i-5p from three-dimensional cultured human umbilical cord mesenchymal stem cells inhibits fibroblast activation in silicosis through targeting TGFBR1.
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Citri Reticulatae Pericarpium alleviates postmyocardial infarction heart failure by upregulating PPARγ expression.
Modification of lysine deacetylation regulates curcumol-induced necroptosis through autophagy in hepatic stellate cells.
CHIR99021 balance TGFβ1 induced human corneal endothelial-to-mesenchymal transition to favor corneal endothelial cell proliferation.
Gli(ko) BMSC: A potential strategy of treatment for renal fibrosis.
Myelin-associated glycoprotein combined with chitin conduit inhibits painful neuroma formation after sciatic nerve transection.
Tracking the response to Pseudomonas aeruginosa infection in ozone-induced chronic obstructive pulmonary disease mouse models.
Molecular feature of arterial remodeling in the brain arteriovenous malformation revealed by arteriovenous shunt rat model and RNA sequencing.
Targeted inhibition of the immunoproteasome blocks endothelial MHC class II antigen presentation to CD4(+) T cells in chronic liver injury.
Capsaicin ameliorates renal fibrosis by inhibiting TGF-β1-Smad2/3 signaling.
Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway.
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
CUX1 promotes epithelial-mesenchymal transition (EMT) in renal fibrosis of UUO model by targeting MMP7.
Spermidine Ameliorates Nonalcoholic Steatohepatitis through Thyroid Hormone-Responsive Protein Signaling and the Gut Microbiota-Mediated Metabolism of Bile Acids.
Generation of a non-integrated induced pluripotent stem cell line from urine cells of a Chinese osteogenesis imperfecta type I patient.
Generation of induced pluripotent stem cells named SMBCi019-A from a methylmalonic acidemia patient carrying the MMACHC mutations.
Establishment of a control induced pluripotent stem cell line SMBCi018-A from a patient with congenital talipes equinovarus.
LncRNA LINC00961 regulates endothelial‑mesenchymal transition via the PTEN‑PI3K‑AKT pathway.
Asperuloside inhibited epithelial-mesenchymal transition in colitis associated cancer via activation of vitamin D receptor.
Peptidome analysis of human intrauterine adhesion tissues and the identification of antifibrotic peptide.
Albumin-induced premature senescence in human renal proximal tubular cells and its relationship with intercellular fibrosis.
Nintedanib Inhibits Endothelial Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis via Focal Adhesion Kinase Activity Reduction.
Interplay of Helicobacter pylori, fibroblasts, and cancer cells induces fibroblast activation and serpin E1 expression by cancer cells to promote gastric tumorigenesis.
Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology.
Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney.
BMSC-derived exosomes protect against kidney injury through regulating klotho in 5/6 nephrectomy rats.
Monochromatic blue light not green light exposure is associated with continuous light-induced hepatic steatosis in high fat diet fed-mice via oxidative stress.
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Histone methyltransferase DOT1L mediates the TGF-β1/Smad3 signaling pathway through epigenetic modification of SYK in myocardial infarction.
Jolkinolide B alleviates renal fibrosis via anti-inflammation and inhibition of epithelial-mesenchymal transition in unilateral ureteral obstruction mice.
Isolation and characterization of secondary metabolites from the leaves of Sauropus spatulifolius Beille and their potential biological assays.
Endothelial cell metabolic memory causes cardiovascular dysfunction in diabetes.
N6-Methyladenosine Modification of CDH1 mRNA Promotes PM2.5-Induced Pulmonary Fibrosis via Mediating Epithelial Mesenchymal Transition.
New IMB16-4 Nanoparticles Improved Oral Bioavailability and Enhanced Anti-Hepatic Fibrosis on Rats.
Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
TiO(2) nanosheets promote the transformation of vascular smooth muscle cells into foam cells in vitro and in vivo through the up-regulation of nuclear factor kappa B subunit 2.
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
IL13 and periostin in active fibrogenic areas of the extrahepatic bile ducts in biliary atresia patients.
A comprehensive analysis on the relationship between BDE-209 exposure and erectile dysfunction.
Branched-chain amino acid transaminase 1 inhibition attenuates childhood asthma in mice by effecting airway remodeling and autophagy.
Poly I:C Exacerbates Airway Inflammation and Remodeling in Cigarette Smoke-Exposed Mice.
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
Deletion of SIRT6 in vascular smooth muscle cells facilitates vascular calcification via suppression of DNA damage repair.
IL-8 exacerbates CCl(4)-induced liver fibrosis in human IL-8-expressing mice via the PI3K/Akt/HIF-1α pathway.
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
Bempedoic acid, an ATP citrate lyase inhibitor, reduces intimal hyperplasia via activation of AMPKα signaling pathway.
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
The Influence of Novel, Biocompatible, and Bioresorbable Poly(3-hydroxyoctanoate) Dressings on Wound Healing in Mice.
Overexpressed DDX3x promotes abdominal aortic aneurysm formation and activates AKT in ApoE knockout mice.
Insights into the mechanism underlying crystalline silica-induced pulmonary fibrosis via transcriptome-wide m(6)A methylation profile.
Development of a human iPSC line (SMBCi017-A) from a healthy donor.
Use of wogonin as a cooperative drug with praziquantel to better combat schistosomiasis.
Long noncoding RNA GAS5 inhibits LX-2 cells activation by suppressing NF-κB signalling through regulation of the miR-433-3p/TLR10 axis.
Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis.
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Construction and identification of an immortalized rat intestinal smooth muscle cell line.
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis.
FXR deficiency in hepatocytes disrupts the bile acid homeostasis and inhibits autophagy to promote liver injury in Schistosoma japonicum-infected mice.
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Morroniside, a novel GATA3 binding molecule, inhibits hepatic stellate cells activation by enhancing lysosomal acid lipase expression.
Circ_0047339 promotes the activation of fibroblasts and affects the development of urethral stricture by targeting the miR-4691-5p/TSP-1 axis.
Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy.
Krill Oil Turns Off TGF-β1 Profibrotic Signaling in the Prevention of Diabetic Nephropathy.
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10.
Antifibrotic and anthelminthic effect of casticin on Schistosoma mansoni-infected BALB/c mice.
Resolution of systemic complications in Schistosoma mansoni-infected mice by concomitant treatment with praziquantel and Schisandrin B.
Botox-A improve the thyroid-associated ophthalmopathy (TAO) orbital fibroblast activation through inhibiting the TGF-β/Smad signaling.
Pharmacological targeting macrophage phenotype via gut-kidney axis ameliorates renal fibrosis in mice.
Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways.
HPV(+) HNSCC-derived exosomal miR-9-5p inhibits TGF-β signaling-mediated fibroblast phenotypic transformation through NOX4.
Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice.
Mechanosensitive Piezo1 channels mediate renal fibrosis.
PEDF is an antifibrosis factor that inhibits the activation of fibroblasts in a bleomycin-induced pulmonary fibrosis rat model.
TRPM2 Promotes Atherosclerotic Progression in a Mouse Model of Atherosclerosis.
MED12 Regulates Smooth Muscle Cell Functions and Participates in the Development of Aortic Dissection.
BRCC36 prevents vascular calcification in chronic kidney disease through the β-catenin signalling pathway.
Effect of Microgroove Structure in PDMS-Based Silicone Implants on Biocompatibility.
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
Aberrantly Expressed Galectin-9 Is Involved in the Immunopathogenesis of Anti-MDA5-Positive Dermatomyositis-Associated Interstitial Lung Disease.
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
STAT3 and IL-6 Contribute to Corticosteroid Resistance in an OVA and Ozone-induced Asthma Model with Neutrophil Infiltration.
Circulating Soluble Suppression of Tumorigenicity 2 Predicts Recurrence After Radiofrequency Ablation of Persistent Atrial Fibrillation.
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.
Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARγ and PGC1α.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Network Pharmacology-Based Mechanistic Investigation of Jinshui Huanxian Formula Acting on Idiopathic Pulmonary Fibrosis.
PP2 Ameliorates Renal Fibrosis by Regulating the NF-κB/COX-2 and PPARγ/UCP2 Pathway in Diabetic Mice.
Ginkgo Biloba Extract EGB761 Ameliorates the Extracellular Matrix Accumulation and Mesenchymal Transformation of Renal Tubules in Diabetic Kidney Disease by Inhibiting Endoplasmic Reticulum Stress.
Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice.
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Wogonin Alleviates Kidney Tubular Epithelial Injury in Diabetic Nephropathy by Inhibiting PI3K/Akt/NF-κB Signaling Pathways.
Fasudil Dichloroacetate Alleviates SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension by Ameliorating Dysfunction of Pulmonary Arterial Smooth Muscle Cells.
Tongluo Yishen Decoction Ameliorates Renal Fibrosis via Regulating Mitochondrial Dysfunction Induced by Oxidative Stress in Unilateral Ureteral Obstruction Rats.
β2-Adrenergic Receptor Enhances the Alternatively Activated Macrophages and Promotes Biliary Injuries Caused by Helminth Infection.
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway.
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
Exploration of the Modulatory Property Mechanism of ELeng Capsule in the Treatment of Endometriosis Using Transcriptomics Combined With Systems Network Pharmacology.
ShenLian Extract Enhances TGF-β Functions in the Macrophage-SMC Unit and Stabilizes Atherosclerotic Plaques.
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.
iTRAQ-Based Proteomics Reveals Gu-Ben-Fang-Xiao Decoction Alleviates Airway Remodeling via Reducing Extracellular Matrix Deposition in a Murine Model of Chronic Remission Asthma.
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Interferon-induced protein 16 expression in colorectal cancer and its correlation with proliferation and immune signature markers.
Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway.
Metformin attenuates vascular pathology by increasing expression of insulin-degrading enzyme in a mixed model of cerebral amyloid angiopathy and type 2 diabetes mellitus.
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.
Effect of different exercise training intensities on age-related cardiac damage in male mice.
The promoting role of Cx43 on the proliferation and migration of arterial smooth muscle cells for angiotensin II-dependent hypertension.
Heat-killed Propionibacterium acnes augment the protective effect of 28-kDa glutathione S-transferases antigen against Schistosoma mansoni infection.
Potential Vasculoprotective Effects of Blackcurrant (Ribes nigrum) Extract in Diabetic KK-A(y) Mice.
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.
Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.
Low-intensity pulsed ultrasound prevents prolonged hypoxia-induced cardiac fibrosis through HIF-1α/DNMT3a pathway via a TRAAK-dependent manner.
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes.
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs.
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
ZC3H4 mediates silica-induced EndoMT via ER stress and autophagy.
Establishment of an iPSC line (CSUXHi004-A) from a patient with Waardenburg syndrome type I caused by a PAX3 splice mutation.
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
MiR-155 promotes colitis-associated intestinal fibrosis by targeting HBP1/Wnt/β-catenin signalling pathway.
Splicing factor SRSF6 mediates pleural fibrosis.
Controlled release of KGF-2 for regulation of wound healing by KGF-2 complexed with "lotus seedpod surface-like" porous microspheres.
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress.
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model.
Amyloid pathology arrangements in Alzheimer's disease brains modulate in vivo seeding capability.
Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway.
Study on the effect of Mongolian medicine Qiwei Qinggan Powder on hepatic fibrosis through JAK2/STAT3 pathway.
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling.
The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.
Apigenin protects mice against 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestasis.
Circular RNA UVRAG Mediated by Alternative Splicing Factor NOVA1 Regulates Adhesion and Migration of Vascular Smooth Muscle Cells.
Photobiomodulation therapy promotes the ATP-binding cassette transporter A1-dependent cholesterol efflux in macrophage to ameliorate atherosclerosis.
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo.
Polysaccharide MCP extracted from Morchella esculenta reduces atherosclerosis in LDLR-deficient mice.
Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway.
Interleukin-6 participates in human pancreatic stellate cell activation and collagen I production via TGF-β1/Smad pathway.
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.
Dopamine D1 receptor alleviates doxorubicin-induced cardiac injury by inhibiting NLRP3 inflammasome.
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.
Type 2 Alveolar Epithelial Cells Differentiated from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Mouse Pulmonary Fibrosis Through β-Catenin-Regulated Cell Apoptosis.
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl(4)-induced hepatic fibrosis in rats in vivo.
Effect of human umbilical cord-derived mesenchymal stem cells on murine model of bronchiolitis obliterans like injury.
Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.
Selective eradication of pluripotent stem cells by inhibiting DHODH activity.
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Comparative cytotoxicity studies of halophenolic disinfection byproducts using human extended pluripotent stem cells.
Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis.
Identification of key pathways and hub genes in the myogenic differentiation of pluripotent stem cell: a bioinformatics and experimental study.
MiR-30c-5p regulates adventitial progenitor cells differentiation to vascular smooth muscle cells through targeting OPG.
The zonula occludens protein family regulates the hepatic barrier system in the murine liver.
Up-regulation of FUT8 inhibits TGF-β1-induced activation of hepatic stellate cells during liver fibrogenesis.
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.
Keratin 1 attenuates hypoxic pulmonary artery hypertension by suppressing pulmonary artery media smooth muscle expansion.
BML-111, the lipoxin A4 agonist, modulates VEGF or CoCl2-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
Fe(3)O(4) magnetic nanoparticles ameliorate albumin-induced tubulointerstitial fibrosis by autophagy related to Rab7.
Osteogenic differentiation and calcification of human aortic smooth muscle cells is induced by the RCN2/STAT3/miR-155-5p feedback loop.
Preparation of a recombinant collagen-peptide (RHC)-conjugated chitosan thermosensitive hydrogel for wound healing.
Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1-WNT2/HGF signaling pathway.
miR-184 targets TP63 to block idiopathic pulmonary fibrosis by inhibiting proliferation and epithelial-mesenchymal transition of airway epithelial cells.
Blackcurrant (Ribes nigrum L.) Extract Exerts Potential Vasculoprotective Effects in Ovariectomized Rats, Including Prevention of Elastin Degradation and Pathological Vascular Remodeling.
Homocysteine promotes cardiac fibrosis by regulating the Akt/FoxO3 pathway.
NAMPT-mediated NAD(+) biosynthesis suppresses activation of hepatic stellate cells and protects against CCl(4)-induced liver fibrosis in mice.
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Vasoactive intestinal peptide attenuates bleomycin-induced murine pulmonary fibrosis by inhibiting epithelial-mesenchymal transition: Restoring autophagy in alveolar epithelial cells.
MicroRNA-210-5p alleviates cardiac fibrosis via targeting transforming growth factor-beta type I receptor in rats on high sodium chloride (NaCl)-based diet.
Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis.
Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension.
Pterostilbene Ameliorates Renal Damage in Diabetic Rats by Suppressing Hyperglycemia with Inhibition of Inflammatory and Fibrotic Responses.
Effects of L-leucine on the properties of spray-dried swellable microparticles with wrinkled surfaces for inhalation therapy of pulmonary fibrosis.
A suitable silicosis mouse model was constructed by repeated inhalation of silica dust via nose.
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
RNO3 QTL regulates vascular structure and arterial stiffness in the spontaneously hypertensive rat.
Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization.
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
PDGF-BB/SA/Dex injectable hydrogels accelerate BMSC-mediated functional full thickness skin wound repair by promoting angiogenesis.
Dysregulations of miR-503-5p and Wnt/β-catenin pathway coordinate in mediating cadmium-induced kidney fibrosis.
Generation of an EFNB2-2A-mCherry reporter human embryonic stem cell line using CRISPR/Cas9-mediated site-specific homologous recombination.
mRNA Transcriptome Analysis of Bone in a Mouse Model of Implant-Associated Staphylococcus aureus Osteomyelitis.
Inhibiting SLC26A4 reverses cardiac hypertrophy in H9C2 cells and in rats.
The Effect of Resveratrol and Quercetin on Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem Cell.
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Sodium Tanshinone IIA Sulfonate Attenuates Erectile Dysfunction in Rats with Hyperlipidemia.
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner.
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
The role of Stim1 in the progression of lupus nephritis in mice.
Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells.
High-Intensity Interval Training Attenuates Ketogenic Diet-Induced Liver Fibrosis in Type 2 Diabetic Mice by Ameliorating TGF-β1/Smad Signaling.
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis.
Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis.
Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence.
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
Fibroblast Growth Factor 1 Ameliorates Diabetes-Induced Liver Injury by Reducing Cellular Stress and Restoring Autophagy.
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
GADD45B Promotes Glucose-Induced Renal Tubular Epithelial-Mesenchymal Transition and Apoptosis via the p38 MAPK and JNK Signaling Pathways.
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis.
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
Abnormal expression of homeobox c6 in the atherosclerotic aorta and its effect on proliferation and migration of rat vascular smooth muscle cells.
Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.
Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner.
Salvianolic acid B and sodium tanshinone II A sulfonate prevent pulmonary fibrosis through anti-inflammatory and anti-fibrotic process.
LncRNA Mical2/miR-203a-3p sponge participates in epithelial-mesenchymal transition by targeting p66Shc in liver fibrosis.
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
CTRP15 derived from cardiac myocytes attenuates TGFβ1-induced fibrotic response in cardiac fibroblasts.
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
Polydeoxyribonucleotide-delivering therapeutic hydrogel for diabetic wound healing.
Spred2-deficiency enhances the proliferation of lung epithelial cells and alleviates pulmonary fibrosis induced by bleomycin.
IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells.
P38 Inhibition Prevents Herpes Simplex Virus Type 1 (HSV-1) Infection in Cultured Corneal Keratocytes.
Inhibition of microRNA-150-5p alleviates cardiac inflammation and fibrosis via targeting Smad7 in high glucose-treated cardiac fibroblasts.
Cancer-associated fibroblasts induce epithelial-mesenchymal transition and cisplatin resistance in ovarian cancer via CXCL12/CXCR4 axis.
OXPHOS-dependent metabolic reprogramming prompts metastatic potential of breast cancer cells under osteogenic differentiation.
Depleting RhoA/Stress Fiber-Organized Fibronectin Matrices on Tumor Cells Non-Autonomously Aggravates Fibroblast-Driven Tumor Cell Growth.
Downregulation of lysyl oxidase in venous malformations: Association with vascular destabilization and sclerotherapy.
Generation and characterization of a human iPSC line derived from congenital clubfoot amniotic fluid cells.
Upregulation of KSRP by miR-27b attenuates schistosomiasis-induced hepatic fibrosis by targeting TGF-β1.
TSP-1 as a novel biological marker of tumor vasculature normalization in colon carcinoma induced by Endostar.
Sirtuin 6 attenuates epithelial-mesenchymal transition by suppressing the TGF-β1/Smad3 pathway and c-Jun in asthma models.
The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation.
LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation.
Ophiocordyceps lanpingensis polysaccharides attenuate pulmonary fibrosis in mice.
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Exploring the potential of engineered exosomes as delivery systems for tumor-suppressor microRNA replacement therapy in ovarian cancer.
LncRNA NNT-AS1 promote glioma cell proliferation and metastases through miR-494-3p/PRMT1 axis.
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
Elk-1 transcriptionally regulates ZC3H4 expression to promote silica-induced epithelial-mesenchymal transition.
Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement.
Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes.
Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis.
TIM-4 interference in Kupffer cells against CCL4-induced liver fibrosis by mediating Akt1/Mitophagy signalling pathway.
Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.
Celastrol exerts anti-inflammatory effect in liver fibrosis via activation of AMPK-SIRT3 signalling.
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
Connexin32 ameliorates renal fibrosis in diabetic mice by promoting K48-linked NADPH oxidase 4 polyubiquitination and degradation.
Long non-coding RNA RNF7 promotes the cardiac fibrosis in rat model via miR-543/THBS1 axis and TGFβ1 activation.
Bleomycin induces epithelial-to-mesenchymal transition via bFGF/PI3K/ESRP1 signaling in pulmonary fibrosis.
Telmisartan inhibits oxalate and calcium oxalate crystal-induced epithelial-mesenchymal transformation via PPAR-γ-AKT/STAT3/p38 MAPK-Snail pathway.
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1α.
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Jiawei Yanghe decoction ameliorates cartilage degradation in vitro and vivo via Wnt/β-catenin signaling pathway.
Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension.
Establishment of a control induced pluripotent stem cell line SMBCi006-A from a healthy male donor.
miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation.
HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications.
Extracellular histones stimulate collagen expression in vitro and promote liver fibrogenesis in a mouse model via the TLR4-MyD88 signaling pathway.
β2-microglobulin as a biomarker of pulmonary fibrosis development in COPD patients.
Apremilast interferes with the TGFβ1-induced transition of human skin fibroblasts into profibrotic myofibroblasts: in vitro study.
Silencing of the lncRNA TUG1 attenuates the epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin.
LncRNA Gm16410 regulates PM(2.5)-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Ammonia exposure causes lung injuries and disturbs pulmonary circadian clock gene network in a pig study.
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
Maladjustment of β-CGRP/α-CGRP Regulation of AQP5 Promotes Transition of Alveolar Epithelial Cell Apoptosis to Pulmonary Fibrosis.
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Trichostatin A Alleviates Renal Interstitial Fibrosis Through Modulation of the M2 Macrophage Subpopulation.
Regulation of NLRP3 inflammasome by CD38 through cADPR-mediated Ca(2+) release in vascular smooth muscle cells in diabetic mice.
Melatonin alleviates cardiac fibrosis via inhibiting lncRNA MALAT1/miR-141-mediated NLRP3 inflammasome and TGF-β1/Smads signaling in diabetic cardiomyopathy.
Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model.
Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke.
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
The metastatic phenotype shift toward myofibroblast of adipose-derived mesenchymal stem cells promotes ovarian cancer progression.
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress.
Bufei Qingyu Granules Inhibit the Development of Systemic Sclerosis via Notch-1/Jagged-2 Signaling Pathway.
Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway.
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Effects of Ethyl Pyruvate on Bile Duct Ligation-Induced Liver Fibrosis by Regulating Nrf2 Pathway and Proinflammatory Cytokines in Rats.
Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF.
Exosomal miRNA-139 in cancer-associated fibroblasts inhibits gastric cancer progression by repressing MMP11 expression.
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia.
Liraglutide Improves Non-Alcoholic Fatty Liver Disease In Diabetic Mice By Modulating Inflammatory Signaling Pathways.
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
Liraglutide ameliorates nonalcoholic fatty liver disease in diabetic mice via the IRS2/PI3K/Akt signaling pathway.
Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway.
Differential regulation of vacuolar H(+) -ATPase subunits by transforming growth factor-β1 in salivary ducts.
The Akt/FoxO/p27(Kip1) axis contributes to the anti-proliferation of pentoxifylline in hypertrophic scars.
Adenovirus‑mediated overexpression of bone morphogenetic protein‑9 promotes methionine choline deficiency‑induced non‑alcoholic steatohepatitis in non‑obese mice.
Downregulating SynCAM and MPP6 expression is associated with ovarian cancer progression.
Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells.
A novel technique to prepare a single cell suspension of isolated quiescent human hepatic stellate cells.
Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis.
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
Chrysophanol attenuates airway inflammation and remodeling through nuclear factor-kappa B signaling pathway in asthma.
Inhibition of vascular neointima hyperplasia by FGF21 associated with FGFR1/Syk/NLRP3 inflammasome pathway in diabetic mice.
Effects of ubiquitin-proteasome inhibitor on the expression levels of TNF-α and TGF-β1 in mice with viral myocarditis.
SPIO nanoparticle-labeled bone marrow mesenchymal stem cells inhibit pulmonary EndoMT induced by SiO(2).
Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression.
Long non-coding RNA TUG1 promotes airway remodelling by suppressing the miR-145-5p/DUSP6 axis in cigarette smoke-induced COPD.
[Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury].
Artemisinin attenuates the development of atherosclerotic lesions by the regulation of vascular smooth muscle cell phenotype switching.
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations.
Inhibition of mitochondrial complex I activity attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration.
Histone deacetylase-1 as a prognostic factor and mediator of gastric cancer progression by enhancing glycolysis.
NAB 2-Expressing Cancer-Associated Fibroblast Promotes HNSCC Progression.
Ribes diacanthum Pall (RDP) ameliorates UUO-induced renal fibrosis via both canonical and non-canonical TGF-β signaling pathways in mice.
AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model.
Isolation and culture of vascular smooth muscle cells from rat placenta.
Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress.
Epidural adipose tissue-derived mesenchymal stem cell activation induced by lung cancer cells promotes malignancy and EMT of lung cancer.
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
c‑Jun N‑terminal kinase/transforming growth factor‑β/Smad3 pathway: Is it associated with endoplasmic reticulum stress‑mediated renal interstitial fibrosis?
miR-205-5p suppresses pulmonary vascular smooth muscle cell proliferation by targeting MICAL2-mediated Erk1/2 signaling.
Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline.
HBOA ameliorates CCl(4)-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Rhynchophylline attenuates allergic bronchial asthma by inhibiting transforming growth factor-β1-mediated Smad and mitogen-activated protein kinase signaling transductions in vivo and in vitro.
CDH11 promotes liver fibrosis via activation of hepatic stellate cells.
The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration.
Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro.
Native nanodiscs from blood inhibit pulmonary fibrosis.
Autophagic flux blockage in alveolar epithelial cells is essential in silica nanoparticle-induced pulmonary fibrosis.
Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway.
miR-194 suppresses epithelial-mesenchymal transition of retinal pigment epithelial cells by directly targeting ZEB1.
Label- and modification-free-based in situ selection of bovine serum albumin specific aptamer.
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
circPUM1 Promotes Tumorigenesis and Progression of Ovarian Cancer by Sponging miR-615-5p and miR-6753-5p.
Salusin-β Promotes Vascular Calcification via Nicotinamide Adenine Dinucleotide Phosphate/Reactive Oxygen Species-Mediated Klotho Downregulation.
Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension.
Calhex(231) Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.
Expression and distribution of PIEZO1 in the mouse urinary tract.
Exploring the Mechanism of Dangguiliuhuang Decoction Against Hepatic Fibrosis by Network Pharmacology and Experimental Validation.
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
Monitoring the Process of Endostar-Induced Tumor Vascular Normalization by Non-contrast Intravoxel Incoherent Motion Diffusion-Weighted MRI.
Inhibition of SIRT2 Alleviates Fibroblast Activation and Renal Tubulointerstitial Fibrosis via MDM2.
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Zoledronate inhibits fibroblasts' proliferation and activation via targeting TGF-β signaling pathway.
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
Thymosin β4 suppresses CCl(4) -induced murine hepatic fibrosis by down-regulating transforming growth factor β receptor-II.
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Anterior gradient 2 as a supervisory marker for tumor vessel normalization induced by anti-angiogenic treatment.
Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury.
NMDA receptor activation inhibits the antifibrotic effect of BM-MSCs on bleomycin-induced pulmonary fibrosis.
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Octreotide attenuates hepatic fibrosis and hepatic stellate cells proliferation and activation by inhibiting Wnt/β-catenin signaling pathway, c-Myc and cyclin D1.
LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.
Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells.
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
circHECTD1 promotes the silica-induced pulmonary endothelial-mesenchymal transition via HECTD1.
Propranolol prevents liver cirrhosis by inhibiting hepatic stellate cell activation mediated by the PDGFR/Akt pathway.
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.
Carnosic acid prevents COL1A2 transcription through the reduction of Smad3 acetylation via the AMPKα1/SIRT1 pathway.
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Epigallocatechin-3-gallate inhibits inflammation and epithelial‑mesenchymal transition through the PI3K/AKT pathway via upregulation of PTEN in asthma.
Toxoplasma gondii GRA15(II) effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Nanoplatform Assembled from a CD44-Targeted Prodrug and Smart Liposomes for Dual Targeting of Tumor Microenvironment and Cancer Cells.
Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase.
Sirt1 activation prevents anti-Thy 1.1 mesangial proliferative glomerulonephritis in the rat through the Nrf2/ARE pathway.
Chemokine (C-X-C motif) ligand 1 is associated with tumor progression and poor prognosis in patients with colorectal cancer.
Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis.
Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.
Upregulation of phosphatase and tensin homolog is essential for the effect of 4-aminopyridine on A549/CDDP cells.
Inhibition of tumor-promoting stroma to enforce subsequently targeting AT(1)R on tumor cells by pathological inspired micelles.
Protective effects of yangonin from an edible botanical Kava against lithocholic acid-induced cholestasis and hepatotoxicity.
5-aminoisoquinoline improves renal function and fibrosis during recovery phase of cisplatin-induced acute kidney injury in rats.
Thymoquinone protects against cardiac damage from doxorubicin-induced heart failure in Sprague-Dawley rats.
Serum levels of WNT1-inducible signaling pathway protein-1 (WISP-1): a noninvasive biomarker of renal fibrosis in subjects with chronic kidney disease.
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
Double Knockdown of PHD1 and Keap1 Attenuated Hypoxia-Induced Injuries in Hepatocytes.
Gypenosides Ameliorate Carbon Tetrachloride-Induced Liver Fibrosis by Inhibiting the Differentiation of Hepatic Progenitor Cells into Myofibroblasts.
Effects of Total Flavone from Rhododendron simsii Planch. Flower on Postischemic Cardiac Dysfunction and Cardiac Remodeling in Rats.
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.
The Hemoglobin Homolog Cytoglobin in Smooth Muscle Inhibits Apoptosis and Regulates Vascular Remodeling.
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.
Inhibition of airway remodeling and inflammation by isoforskolin in PDGF-induced rat ASMCs and OVA-induced rat asthma model.
Codelivery for Paclitaxel and Bcl-2 Conversion Gene by PHB-PDMAEMA Amphiphilic Cationic Copolymer for Effective Drug Resistant Cancer Therapy.
Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β‑catenin signaling pathway.
Crocetin inhibits the proliferation, migration and TGF-β(2)-induced epithelial-mesenchymal transition of retinal pigment epithelial cells.
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.
Production of human mutant biologically active hepatocyte growth factor in Chinese hamster ovary cells.
FAM3B mediates high glucose-induced vascular smooth muscle cell proliferation and migration via inhibition of miR-322-5p.
Role of heparin in pulmonary cell populations in an in-vitro model of acute lung injury.
Highly Selective Targeting of Hepatic Stellate Cells for Liver Fibrosis Treatment Using a d-Enantiomeric Peptide Ligand of Fn14 Identified by Mirror-Image mRNA Display.
Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells.
Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase.
Dual Function for Mature Vascular Smooth Muscle Cells During Arteriovenous Fistula Remodeling.
Secreted phospholipase A2 of Clonorchis sinensis activates hepatic stellate cells through a pathway involving JNK signalling.
Losartan Attenuates Scar Formation in Filtering Bleb After Trabeculectomy.
miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions.
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
LncRNA-ATB/microRNA-200a/β-catenin regulatory axis involved in the progression of HCV-related hepatic fibrosis.
Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis.
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
CYP2J2 metabolites, epoxyeicosatrienoic acids, attenuate Ang II-induced cardiac fibrotic response by targeting Gα(12/13).
Conjugation of gold nanoparticles and recombinant human endostatin modulates vascular normalization via interruption of anterior gradient 2-mediated angiogenesis.
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.
Interaction network of coexpressed mRNA, miRNA, and lncRNA activated by TGF‑β1 regulates EMT in human pulmonary epithelial cell.
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Atrial natriuretic peptide: A novel mediator for TGF-β1-induced epithelial-mesenchymal transition in 16HBE-14o and A549 cells.
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.
MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
A comparison of incidences of bladder neck contracture of 80- versus 180-W GreenLight laser photoselective vaporization of benign prostatic hyperplasia.
Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE-/- mice.
IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells.
Lymph node metastasis of primary endometrial cancers: Associated proteins revealed by MALDI imaging.
MicroRNA-548a-5p promotes proliferation and inhibits apoptosis in hepatocellular carcinoma cells by targeting Tg737.
Carboxy-terminal modulator protein attenuated extracellular matrix deposit by inhibiting phospho-Akt, TGF-β1 and α-SMA in kidneys of diabetic mice.
In vitro differentiation of endometrial regenerative cells into smooth muscle cells: Α potential approach for the management of pelvic organ prolapse.
Gold Nanoparticle-Mediated Targeted Delivery of Recombinant Human Endostatin Normalizes Tumour Vasculature and Improves Cancer Therapy.
Effect of astragalus injection on renal tubular epithelial transdifferentiation in type 2 diabetic mice.
Clonorchis sinensis lysophospholipase inhibits TGF-β1-induced expression of pro-fibrogenic genes through attenuating the activations of Smad3, JNK2, and ERK1/2 in hepatic stellate cell line LX-2.
Mesenchymal stem cell-conditioned media suppresses inflammation-associated overproliferation of pulmonary artery smooth muscle cells in a rat model of pulmonary hypertension.
Apobec-1 Complementation Factor (A1CF) Inhibits Epithelial-Mesenchymal Transition and Migration of Normal Rat Kidney Proximal Tubular Epithelial Cells.
PTP1B confers liver fibrosis by regulating the activation of hepatic stellate cells.
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
Quantitative Proteomic Analysis of Escherichia coli Heat-Labile Toxin B Subunit (LTB) with Enterovirus 71 (EV71) Subunit VP1.
The germline-enriched Ppp1r36 promotes autophagy.
C1q/tumor necrosis factor-related protein-6 attenuates post-infarct cardiac fibrosis by targeting RhoA/MRTF-A pathway and inhibiting myofibroblast differentiation.
Valsartan Promoting Atherosclerotic Plaque Stabilization by Upregulating Renalase: A Potential-Related Gene of Atherosclerosis.
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Stroma derived COL6A3 is a potential prognosis marker of colorectal carcinoma revealed by quantitative proteomics.
CD73 regulates vascular smooth muscle cell functions and facilitates atherosclerotic plaque formation.
Transarterial chemoembolization aggravated peritumoral fibrosis via hypoxia-inducible factor-1α dependent pathway in hepatocellular carcinoma.
Irradiated fibroblasts promote epithelial-mesenchymal transition and HDGF expression of esophageal squamous cell carcinoma.
miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/β-catenin signaling pathway.
CTRP3 attenuates post-infarct cardiac fibrosis by targeting Smad3 activation and inhibiting myofibroblast differentiation.
Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction.
Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties.
Human Parechovirus 3 Meningitis and Fatal Leukoencephalopathy.
Beta-casomorphin-7 prevents epithelial-mesenchymal transdifferentiation of NRK-52E cells at high glucose level: Involvement of AngII-TGF-β1 pathway.
Involvement of cAMP-PKA pathway in adenosine A1 and A2A receptor-mediated regulation of acetaldehyde-induced activation of HSCs.
Hesperetin derivative-7 inhibits PDGF-BB-induced hepatic stellate cell activation and proliferation by targeting Wnt/β-catenin pathway.
Potent effects of dioscin against liver fibrosis.
Rosiglitazone inhibits TGF-β 1 induced activation of human Tenon fibroblasts via p38 signal pathway.
Regulating inflammation using acid-responsive electrospun fibrous scaffolds for skin scarless healing.
Endoplasmic reticulum stress-induced hepatic stellate cell apoptosis through calcium-mediated JNK/P38 MAPK and Calpain/Caspase-12 pathways.
Association between the hypomethylation of osteopontin and integrin β3 promoters and vascular smooth muscle cell phenotype switching in great saphenous varicose veins.
Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation.
Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats.
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Participation of miR-200a in TGF-β1-mediated hepatic stellate cell activation.
Effects and mechanism of dehydroepiandrosterone on epithelial-mesenchymal transition in bronchial epithelial cells.
Hyperthermia-conditioned OECs serum-free-conditioned medium induce NSC differentiation into neuron more efficiently by the upregulation of HIF-1 alpha and binding activity.
Repression of Smad7 mediated by DNMT1 determines hepatic stellate cell activation and liver fibrosis in rats.
Antifibrotic effect of curcumin in TGF-β 1-induced myofibroblasts from human oral mucosa.
MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4.
β-Casomorphin-7 attenuates the development of nephropathy in type I diabetes via inhibition of epithelial-mesenchymal transition of renal tubular epithelial cells.
Fusion between cancer cells and myofibroblasts is involved in osteosarcoma.
BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2.
Li H, Li J, Wang T, Sun K, Huang G, Cao Y, Wu F, Xu A
International journal of biological sciences 2024;20(4):1160-1179
International journal of biological sciences 2024;20(4):1160-1179
Combined Placental Mesenchymal Stem Cells with Guided Nanoparticles Effective Against Diabetic Nephropathy in Mouse Model.
Wang K, Liu T, Zhang Y, Lv H, Yao H, Zhao Y, Li J, Li X
International journal of nanomedicine 2024;19:901-915
International journal of nanomedicine 2024;19:901-915
Nanofabrications of Erythrocyte Membrane-Coated Telmisartan Delivery System Effective for Radiosensitivity of Tumor Cells in Mice Model.
Chen S, Wang C, Meng Y, Li P, Pan Y, He M, Ni X
International journal of nanomedicine 2024;19:1487-1508
International journal of nanomedicine 2024;19:1487-1508
RASSF4 Attenuates Metabolic Dysfunction-Associated Steatotic Liver Disease Progression via Hippo Signaling and Suppresses Hepatocarcinogenesis.
Xu C, Fang T, Qu J, Miao Y, Tian L, Zhang M, Zhuang H, Sun B, Chen L
Cellular and molecular gastroenterology and hepatology 2024;18(2):101348
Cellular and molecular gastroenterology and hepatology 2024;18(2):101348
The Mechanism of Catalpol to Improve Oxidative Damage of Dermal Fibroblasts Based on Nrf2/HO-1 Signaling Pathway.
Lang X, Xu L, Li L, Feng X
Drug design, development and therapy 2024;18:2287-2297
Drug design, development and therapy 2024;18:2287-2297
Claudin-2 Mediates the Proximal Tubular Epithelial Cell-Fibroblast Crosstalk via Paracrine CTGF.
Guo C, Jiao M, Cui Y, Li P, Yao J, Dong J, Liao L
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:55-73
Diabetes, metabolic syndrome and obesity : targets and therapy 2024;17:55-73
Seed and Soil: Consensus Molecular Subgroups (CMS) and Tumor Microenvironment Features Between Primary Lesions and Metastases of Different Organ Sites in Colorectal Cancer.
Luo Q, Quan Y, Liu W, Wu Z, Qiu W, Liang W, Yang P, Huang Q, Li G, Wei J, Wang Q, Shen F, Li W, He F, Cao J
Cancer management and research 2024;16:225-243
Cancer management and research 2024;16:225-243
Inhibition of ACOX1 enhances the therapeutic efficacy of obeticholic acid in treating non-alcoholic fatty liver disease and mitigates its lipotoxicity.
Yang Y, Yuan W, He K, Lin C, Du S, Kou Y, Nie B
Frontiers in pharmacology 2024;15:1366479
Frontiers in pharmacology 2024;15:1366479
HIF2A mediates lineage transition to aggressive phenotype of cancer-associated fibroblasts in lung cancer brain metastasis.
You M, Fu M, Shen Z, Feng Y, Zhang L, Zhu X, Zhuang Z, Mao Y, Hua W
Oncoimmunology 2024;13(1):2356942
Oncoimmunology 2024;13(1):2356942
Hypoxia macrophage-derived exosomal miR-26b-5p targeting PTEN promotes the development of keloids.
Dai S, Xu M, Pang Q, Sun J, Lin X, Chu X, Guo C, Xu J
Burns & trauma 2024;12:tkad036
Burns & trauma 2024;12:tkad036
The clinical impact of macrophage polarity after Kasai portoenterostomy in biliary atresia.
Nagayabu K, Fumino S, Shimamura A, Sengoku Y, Higashi M, Iguchi M, Aoi S, Saya S, Hirai M, Ogi H, Miyagawa-Hayashino A, Konishi E, Itoh K, Tajiri T, Ono S
Frontiers in pediatrics 2024;12:1338131
Frontiers in pediatrics 2024;12:1338131
Enhancing Fat Transplantation Efficiency in a Mouse Model through Pretreatment of Adipose-Derived Stem Cells with RIP3 Inhibitors.
Yang Z, Lu H, Gao Q, Yuan X, Hu Y, Qi Z
Aesthetic plastic surgery 2024 Sep;48(17):3488-3499
Aesthetic plastic surgery 2024 Sep;48(17):3488-3499
Morroniside improves AngII-induced cardiac fibroblast proliferation, migration, and extracellular matrix deposition by blocking p38/JNK signaling pathway through the downregulation of KLF5.
Zheng H, Yang L, Huang H, Lin Y, Chen L
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6611-6621
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):6611-6621
Early growth response protein 2 promotes partial epithelial-mesenchymal transition by phosphorylating Smad3 during renal fibrosis.
Song A, Yan R, Xiong W, Xiang H, Huang J, Jiang A, Zhang C
Translational research : the journal of laboratory and clinical medicine 2024 Sep;271:13-25
Translational research : the journal of laboratory and clinical medicine 2024 Sep;271:13-25
Knockdown of programmed cell death factor 4 restores erectile function by attenuating apoptosis in rats with bilateral cavernous nerve crush injury.
Ge Y, Xia T, Feng Z, Xi Y, Hu D, Hong Y, Tang B, Wu J, Chen J, Xiao H
Andrology 2024 Sep;12(6):1439-1448
Andrology 2024 Sep;12(6):1439-1448
Obstructive Sleep Apnea Syndrome Exacerbates NASH Progression via Selective Autophagy-Mediated Eepd1 Degradation.
Xiong J, Xu Y, Wang N, Wang S, Zhang Y, Lu S, Zhang X, Liang X, Liu C, Jiang Q, Xu J, Qian Q, Zhou P, Yin L, Liu F, Chen S, Yin S, Liu J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2405955
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(35):e2405955
Uremic Toxin Receptor AhR Facilitates Renal Senescence and Fibrosis via Suppressing Mitochondrial Biogenesis.
Xie H, Yang N, Lu L, Sun X, Li J, Wang X, Guo H, Zhou L, Liu J, Wu H, Yu C, Zhang W, Lu L
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402066
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Sep;11(33):e2402066
Insulin-transferrin-selenium promote formation of tissue-engineered vascular grafts in early stage of culture.
Sun X, Wang N, Jiang H, Liu Q, Xiao C, Xu J, Wu Y, Mei J, Wu S, Lin Z
Preparative biochemistry & biotechnology 2024 Oct;54(9):1186-1195
Preparative biochemistry & biotechnology 2024 Oct;54(9):1186-1195
Toll-Like Receptor 9 Aggravates Pulmonary Fibrosis by Promoting NLRP3-Mediated Pyroptosis of Alveolar Epithelial Cells.
Ren C, Wang Q, Fan S, Mi T, Zhang Z, He D
Inflammation 2024 Oct;47(5):1744-1761
Inflammation 2024 Oct;47(5):1744-1761
Target NF-κB p65 for preventing posttraumatic joint contracture in rats.
Kong L, Liang Y, Hou J, Zhang W, Jiang S
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 Oct;42(10):2172-2180
Journal of orthopaedic research : official publication of the Orthopaedic Research Society 2024 Oct;42(10):2172-2180
Neutrophil-Mediated Nanozyme Delivery System for Acute Kidney Injury Therapy.
Yang Y, Du J, Gan J, Song X, Shu J, An C, Lu L, Wei H, Che J, Zhao X
Advanced healthcare materials 2024 Oct;13(26):e2401198
Advanced healthcare materials 2024 Oct;13(26):e2401198
Transcriptomic analysis reveals the critical role of chemokine signaling in the anti-atherosclerosis effect of Xuefu Zhuyu decoction.
Jia D, Zhao M, Zhang X, Cheng X, Wei Q, Lou L, Zhao Y, Jin Q, Chen M, Zhang D
Journal of ethnopharmacology 2024 Oct 5;332:118245
Journal of ethnopharmacology 2024 Oct 5;332:118245
Mangiferin alleviates diabetic pulmonary fibrosis in mice via inhibiting endothelial-mesenchymal transition through AMPK/FoxO3/SIRT3 axis.
Fu TL, Li GR, Li DH, He RY, Liu BH, Xiong R, Xu CZ, Lu ZL, Song CK, Qiu HL, Wang WJ, Zou SS, Yi K, Li N, Geng Q
Acta pharmacologica Sinica 2024 May;45(5):1002-1018
Acta pharmacologica Sinica 2024 May;45(5):1002-1018
Colorectal cancer cells secreting DKK4 transform fibroblasts to promote tumour metastasis.
Li X, Chen Y, Lu R, Hu M, Gu L, Huang Q, Meng W, Zhu H, Fan C, Zhou Z, Mo X
Oncogene 2024 May;43(20):1506-1521
Oncogene 2024 May;43(20):1506-1521
Dihydrocapsaicin suppresses the STING-mediated accumulation of ROS and NLRP3 inflammasome and alleviates apoptosis after ischemia-reperfusion injury of perforator skin flap.
Lai Y, Yang N, Chen X, Ma X, Chen Z, Dong C, Yu G, Huang Y, Shi D, Fang P, Fu K, Jiang R, Mao C, Ding J, Gao W
Phytotherapy research : PTR 2024 May;38(5):2539-2559
Phytotherapy research : PTR 2024 May;38(5):2539-2559
Lacosamide alleviates bilateral cavernous nerve injury-induced erectile dysfunction in the rat model by ameliorating pathological changes in the corpus cavernosum.
Yao L, Cong R, Zhou X, Zhou X, Ji C, Wei X, Meng X, Song N
International journal of impotence research 2024 May;36(3):283-290
International journal of impotence research 2024 May;36(3):283-290
Sirt7/HIC1 complex participates in hyperglycaemia-mediated EndMT via modulation of SDC1 expression in diabetic kidney disease and metabolic memory.
Lu L, Zhu M, Wu Q, Sun Z, Chen X, Miao C
Journal of cellular and molecular medicine 2024 May;28(9):e18336
Journal of cellular and molecular medicine 2024 May;28(9):e18336
Dexamethasone promotes renal fibrosis by upregulating ILT4 expression in myeloid-derived suppressor cells.
Gu X, Zhang L, Sun M, Zhou Y, Ji J, Xu Y, You J, Deng Z
Journal of cellular and molecular medicine 2024 May;28(9):e18310
Journal of cellular and molecular medicine 2024 May;28(9):e18310
Inhibition of STAT3 by S3I-201 suppress peritoneal fibroblast phenotype conversion and alleviate peritoneal fibrosis.
Song Q, Li H, Yan H, Yu Z, Li Z, Yuan J, Jiang N, Ni Z, Gu L, Fang W
Journal of cellular and molecular medicine 2024 May;28(10):e18381
Journal of cellular and molecular medicine 2024 May;28(10):e18381
CNPY2 governs PDGF‑BB‑treated vascular smooth muscle cell proliferation, migration and phenotypic transformation via the Akt/mTOR/GSK‑3β signaling pathway.
Sun H, Wang X, Ma L, Li X, Jin W, Yang Y
Experimental and therapeutic medicine 2024 May;27(5):197
Experimental and therapeutic medicine 2024 May;27(5):197
Riboflavin protects against pancreatic cancer metastasis by targeting TGF-β receptor 1.
Zhao J, Liu X, Jin X, Dong T, Gao X, Wang J, Li Y, Ma E
Bioorganic chemistry 2024 May;146:107274
Bioorganic chemistry 2024 May;146:107274
Paris polyphylla ethanol extract and polyphyllin I ameliorate adenomyosis by inhibiting epithelial-mesenchymal transition.
Shi YX, Xu L, Wang X, Zhang KK, Zhang CY, Liu HY, Ding PP, Shi W, Liu ZY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155461
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 May;127:155461
Midkine promotes renal fibrosis by stabilizing C/EBPβ to facilitate endothelial-mesenchymal transition.
Xu C, Chen J, Liang L, Chen S, Niu X, Sang R, Yang C, Rong R
Communications biology 2024 May 7;7(1):544
Communications biology 2024 May 7;7(1):544
Effects of Nanoparticle-Mediated Dihydromyricetin to Diabetic Wounds: An In Vivo Study.
Wang ZN, Ma JC, Xi MF, Yin D, Jiang LF, Qi J
Journal of burn care & research : official publication of the American Burn Association 2024 May 6;45(3):644-654
Journal of burn care & research : official publication of the American Burn Association 2024 May 6;45(3):644-654
Naringenin reduces oxidative stress and necroptosis, apoptosis, and pyroptosis in random-pattern skin flaps by enhancing autophagy.
Jiang S, Ma F, Lou J, Li J, Shang X, Li Y, Wu J, Xu S
European journal of pharmacology 2024 May 5;970:176455
European journal of pharmacology 2024 May 5;970:176455
Senegenin Attenuates Pulmonary Fibrosis by Inhibiting Oxidative-Stress-Induced Epithelial Cell Senescence through Activation of the Sirt1/Pgc-1α Signaling Pathway.
Zeng Q, Luo Y, Sang X, Liao M, Wen B, Hu Z, Sun M, Luo Z, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 May 31;13(6)
Antioxidants (Basel, Switzerland) 2024 May 31;13(6)
CXCL4:NLRP3-mediated pyroptosis product that regulates cardiac fibrosis.
Wei J, Peng MY, Wang SN, Lu HX
International immunopharmacology 2024 May 30;133:112096
International immunopharmacology 2024 May 30;133:112096
Podocyte-Specific Deletion of MCP-1 Fails to Protect against Angiotensin II- or Adriamycin-Induced Glomerular Disease.
Bondi CD, Hartman HL, Rush BM, Tan RJ
International journal of molecular sciences 2024 May 3;25(9)
International journal of molecular sciences 2024 May 3;25(9)
Design, Synthesis, and Evaluation of Dihydropyrimidine Derivatives as Selective PDE1 Inhibitors for the Treatment of Liver Fibrosis.
Zhao ZJ, Jiang MY, Huang MX, Yang YY, Feng LL, Zhang C, Huang YY, Luo HB, Wu Y
Journal of medicinal chemistry 2024 May 23;67(10):8309-8322
Journal of medicinal chemistry 2024 May 23;67(10):8309-8322
Modeling alcohol-associated liver disease in humans using adipose stromal or stem cell-derived organoids.
Bi G, Zhang X, Li W, Lu X, He X, Li Y, Bai R, Zhang H
Cell reports methods 2024 May 20;4(5):100778
Cell reports methods 2024 May 20;4(5):100778
Enhanced Vascular-like Network Formation of Encapsulated HUVECs and ADSCs Coculture in Growth Factors Conjugated GelMA Hydrogels.
Bupphathong S, Lim J, Fang HW, Tao HY, Yeh CE, Ku TA, Huang W, Kuo TY, Lin CH
ACS biomaterials science & engineering 2024 May 13;10(5):3306-3315
ACS biomaterials science & engineering 2024 May 13;10(5):3306-3315
Withanolides from the active extract of Physalis angulate and their anti-hepatic fibrosis effects.
Wang FR, Peng ML, Zhu QF, Yu LL, Zhang LJ, Xu SY, Wang Q, Li J, He X, Liao SG, Ao JL, Xu GB
Journal of ethnopharmacology 2024 May 10;325:117830
Journal of ethnopharmacology 2024 May 10;325:117830
The SP1/SIRT1/ACLY signaling axis mediates fatty acid oxidation in renal ischemia-reperfusion-induced renal fibrosis.
Wu H, Wang L, Kang P, Zhou X, Li W, Xia Z
International immunopharmacology 2024 May 10;132:112002
International immunopharmacology 2024 May 10;132:112002
SIRT1 activation ameliorates rhesus monkey liver fibrosis by inhibiting the TGF-β/smad signaling pathway.
Xia Y, Luo Q, Gao Q, Huang C, Chen P, Zou Y, Chen X, Liu W, Chen Z
Chemico-biological interactions 2024 May 1;394:110979
Chemico-biological interactions 2024 May 1;394:110979
Echinacoside Exerts Antihepatic Fibrosis Effects in High-Fat Mice Model by Modulating the ACVR2A-Smad Pathway.
Liang J, Chen T, Xu H, Wang T, Gong Q, Li T, Liu X, Wang J, Wang Y, Xiong L
Molecular nutrition & food research 2024 Mar;68(6):e2300553
Molecular nutrition & food research 2024 Mar;68(6):e2300553
Multi-omic profiling of clear cell renal cell carcinoma identifies metabolic reprogramming associated with disease progression.
Hu J, Wang SG, Hou Y, Chen Z, Liu L, Li R, Li N, Zhou L, Yang Y, Wang L, Wang L, Yang X, Lei Y, Deng C, Li Y, Deng Z, Ding Y, Kuang Y, Yao Z, Xun Y, Li F, Li H, Hu J, Liu Z, Wang T, Hao Y, Jiao X, Guan W, Tao Z, Ren S, Chen K
Nature genetics 2024 Mar;56(3):442-457
Nature genetics 2024 Mar;56(3):442-457
MitoQ Alleviated PM(2.5) Induced Pulmonary Epithelial Cells Injury by Inhibiting Mitochondrial-Mediated Apoptosis.
Weng AB, Deng MM, Liu XD, Wang HB, Lin Q
Iranian journal of public health 2024 Mar;53(3):614-624
Iranian journal of public health 2024 Mar;53(3):614-624
Crocin Inhibits Orbital Fibroblasts Fibrosis in Thyroid-Associated Ophthalmopathy.
Xu S, Mao H
Current eye research 2024 Mar;49(3):330-337
Current eye research 2024 Mar;49(3):330-337
TRIM65 promotes vascular smooth muscle cell phenotypic transformation by activating PI3K/Akt/mTOR signaling during atherogenesis.
Zhou ZX, Ma XF, Xiong WH, Ren Z, Jiang M, Deng NH, Zhou BB, Liu HT, Zhou K, Hu HJ, Tang HF, Zheng H, Jiang ZS
Atherosclerosis 2024 Mar;390:117430
Atherosclerosis 2024 Mar;390:117430
Knockdown of ARHGAP24 reduces intimal hyperplasia through inhibiting the proliferation and phenotypic switching of smooth muscle cells possibly by inactivating both AKT and ERK1/2 signaling pathways.
Liu W, Han J, Yang Q, Xia L, Chen C, Song J, Cai Y
Biochemistry and biophysics reports 2024 Mar;37:101591
Biochemistry and biophysics reports 2024 Mar;37:101591
Integrin β8 prevents pericyte-myofibroblast transition and renal fibrosis through inhibiting the TGF-β1/TGFBR1/Smad3 pathway in diabetic kidney disease.
Cao Y, Su H, Zeng J, Xie Y, Liu Z, Liu F, Qiu Y, Yi F, Lin J, Hammes HP, Zhang C
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Translational research : the journal of laboratory and clinical medicine 2024 Mar;265:36-50
Arctium lappa L. polysaccharides enhanced the therapeutic effects of nasal ectomesenchymal stem cells against liver fibrosis by inhibiting the Wnt/β-catenin pathway.
Xiang W, Yin G, Liu H, Wei J, Yu X, Xie Y, Zhang L, XueTang, Jiang W, Lu N
International journal of biological macromolecules 2024 Mar;261(Pt 1):129670
International journal of biological macromolecules 2024 Mar;261(Pt 1):129670
Primary cilia are critical for tracheoesophageal septation.
Fitzsimons LA, Tasouri E, Willaredt MA, Stetson D, Gojak C, Kirsch J, Gardner HAR, Gorgas K, Tucker KL
Developmental dynamics : an official publication of the American Association of Anatomists 2024 Mar;253(3):312-332
Developmental dynamics : an official publication of the American Association of Anatomists 2024 Mar;253(3):312-332
Machine learning and single-cell transcriptome profiling reveal regulation of fibroblast activation through THBS2/TGFβ1/P-Smad2/3 signalling pathway in hypertrophic scar.
Song B, Zhu Y, Zhao Y, Wang K, Peng Y, Chen L, Yu Z, Song B
International wound journal 2024 Mar;21(3):e14481
International wound journal 2024 Mar;21(3):e14481
Natural intestinal metabolite xylitol reduces BRD4 levels to mitigate renal fibrosis.
Tan Z, Wang Z, Zeng Q, Liu X, Zhang Y, Li S, Huang J, Zeng Y, Huang Z, Jin C, Fu N, Zhao Q, Mu Y, Wang Z, Xiao J, Yang H, Ke G
Clinical and translational science 2024 Mar;17(3):e13770
Clinical and translational science 2024 Mar;17(3):e13770
Structure-based design and synthesis of anti-fibrotic compounds derived from para-positioned 3,4,5-trisubstituted benzene.
Hong W, Xiao T, Lin G, Liu C, Li H, Li Y, Hu H, Wu S, Wang S, Liang Z, Lin T, Liu J, Chen X
Bioorganic chemistry 2024 Mar;144:107113
Bioorganic chemistry 2024 Mar;144:107113
Bacterial Cellulose-Based Bandages with Integrated Antibacteria and Electrical Stimulation for Advanced Wound Management.
Liu X, Cai Z, Pei M, Zeng H, Yang L, Cao W, Zhou X, Chen F
Advanced healthcare materials 2024 Mar;13(7):e2302893
Advanced healthcare materials 2024 Mar;13(7):e2302893
Network pharmacology and transcriptomic profiling elucidate the therapeutic effects of Ranunculus ternatus Thunb on liver fibrosis via MK3-NF-κB inhibition.
Han L, Lin G, Li J, Zhang Q, Ran T, Huang T, Hu R, Feng S, Zou G, Chen S, Zhao X
Aging 2024 Mar 8;16(5):4759-4777
Aging 2024 Mar 8;16(5):4759-4777
Macrophage-derived exosomal HMGB3 regulates silica-induced pulmonary inflammation by promoting M1 macrophage polarization and recruitment.
Qin X, Niu Z, Chen H, Hu Y
Particle and fibre toxicology 2024 Mar 7;21(1):12
Particle and fibre toxicology 2024 Mar 7;21(1):12
Spinosin inhibits activated hepatic stellate cell to attenuate liver fibrosis by targeting Nur77/ASK1/p38 MAPK signaling pathway.
Lin G, Li W, Hong W, Zhu D, Hu H, Fu J, Gao Y, Chen S, Chai D, Zeng JZ
European journal of pharmacology 2024 Mar 5;966:176270
European journal of pharmacology 2024 Mar 5;966:176270
Augmentation of scleral glycolysis promotes myopia through histone lactylation.
Lin X, Lei Y, Pan M, Hu C, Xie B, Wu W, Su J, Li Y, Tan Y, Wei X, Xue Z, Xu R, Di M, Deng H, Liu S, Yang X, Qu J, Chen W, Zhou X, Zhao F
Cell metabolism 2024 Mar 5;36(3):511-525.e7
Cell metabolism 2024 Mar 5;36(3):511-525.e7
Early-life ruminal microbiome-derived indole-3-carboxaldehyde and prostaglandin D2 are effective promoters of rumen development.
Sun D, Bian G, Zhang K, Liu N, Yin Y, Hou Y, Xie F, Zhu W, Mao S, Liu J
Genome biology 2024 Mar 4;25(1):64
Genome biology 2024 Mar 4;25(1):64
Tryptanthrin promotes pressure ulcers healing in mice by inhibiting macrophage-mediated inflammation via cGAS/STING pathways.
He Y, Yue J, Teng Y, Fan Z, Jia M, Teng H, Zhuge L
International immunopharmacology 2024 Mar 30;130:111687
International immunopharmacology 2024 Mar 30;130:111687
Curculigoside Attenuates Endoplasmic Reticulum Stress-Induced Epithelial Cell and Fibroblast Senescence by Regulating the SIRT1-P300 Signaling Pathway.
Xie W, Deng L, Qian R, Huang X, Liu W, Tang S
Antioxidants (Basel, Switzerland) 2024 Mar 29;13(4)
Antioxidants (Basel, Switzerland) 2024 Mar 29;13(4)
Integrating Network Pharmacology and In Vitro Experimental Verification Revealing Bushenhuoxue Recipe Against Intrauterine Adhesions via PI3K-AKT Signaling Pathway.
Wang L, Zhuang L, Lu Y, Jia J, Chen C, Zhang Y, Hong Z, Wang X
Biochemical genetics 2024 Mar 19;
Biochemical genetics 2024 Mar 19;
Increased extracellular matrix stiffness regulates myofibroblast transformation through induction of autophagy-mediated Kindlin-2 cytoplasmic translocation.
Zhao Z, Han W, Huang G, He Y, Zuo X, Hong L
Experimental cell research 2024 Mar 15;436(2):113974
Experimental cell research 2024 Mar 15;436(2):113974
The mechanisms and therapeutic potential of clopidogrel in mitigating diabetic cardiomyopathy in db/db mice.
Li B, Zhang Y, Zheng Y, Cai H
iScience 2024 Mar 15;27(3):109134
iScience 2024 Mar 15;27(3):109134
Cancer-associated fibroblast-secreted FGF7 as an ovarian cancer progression promoter.
Feng S, Ding B, Dai Z, Yin H, Ding Y, Liu S, Zhang K, Lin H, Xiao Z, Shen Y
Journal of translational medicine 2024 Mar 15;22(1):280
Journal of translational medicine 2024 Mar 15;22(1):280
Nitric oxide nano-reactor DNMF/PLGA enables tumor vascular microenvironment and chemo-hyperthermia synergetic therapy.
Wang R, Cheng L, He L, Du C, Wang H, Peng B, Yu X, Liu W, Luo W, Ran H, Yang L
Journal of nanobiotechnology 2024 Mar 13;22(1):110
Journal of nanobiotechnology 2024 Mar 13;22(1):110
Bicyclol alleviates obesity-induced renal injury by inhibiting JNK and NF-κB-mediated inflammation.
Zhang L, Wang J, Xu T, Luo Y, Cai Z, Jiang Y, Jin T, Bao H, Wang Y
International immunopharmacology 2024 Mar 10;129:111609
International immunopharmacology 2024 Mar 10;129:111609
Generation of a human induced pluripotent stem cell line harboring heteroplasmic m.3243A > G mutation in MT-TL1 gene.
Song M, Chen S, Zhang M, Hu S, Lei W, Yu M
Stem cell research 2024 Jun;77:103387
Stem cell research 2024 Jun;77:103387
Bioresponsive nanocomplex integrating cancer-associated fibroblast deactivation and immunogenic chemotherapy for rebuilding immune-excluded tumors.
Liu L, Zhang B, Wu X, Cheng G, Han X, Xin X, Qin C, Yang L, Huo M, Yin L
Nanomedicine : nanotechnology, biology, and medicine 2024 Jun;58:102743
Nanomedicine : nanotechnology, biology, and medicine 2024 Jun;58:102743
A 3D spheroid model of quadruple cell co-culture with improved liver functions for hepatotoxicity prediction.
Sun B, Liang Z, Wang Y, Yu Y, Zhou X, Geng X, Li B
Toxicology 2024 Jun;505:153829
Toxicology 2024 Jun;505:153829
Stiffened tumor microenvironment enhances perineural invasion in breast cancer via integrin signaling.
Han B, Guan X, Ma M, Liang B, Ren L, Liu Y, Du Y, Jiang SH, Song D
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):867-882
Cellular oncology (Dordrecht, Netherlands) 2024 Jun;47(3):867-882
TRPC6 Knockout Alleviates Renal Fibrosis through PI3K/AKT/GSK3B Pathway.
Sun AB, Li FH, Zhu L, Zeng XX, Zhu M, Lei QH, Liao YH
Current medical science 2024 Jun;44(3):589-602
Current medical science 2024 Jun;44(3):589-602
Dihydromyricetin alleviates inflammatory bowel disease associated intestinal fibrosis by inducing autophagy through the PI3K/AKT/mTOR signaling pathway.
Wang X, Li X, Ma X, Zhang L, Han T, Zhang D
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4183-4194
Naunyn-Schmiedeberg's archives of pharmacology 2024 Jun;397(6):4183-4194
CILP2 promotes hypertrophic scar through Snail acetylation by interaction with ACLY.
Wang J, Du J, Wang Y, Song Y, Wu J, Wang T, Yu Z, Song B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167202
Bile acids induce liver fibrosis through the NLRP3 inflammasome pathway and the mechanism of FXR inhibition of NLRP3 activation.
Feng S, Xie X, Li J, Xu X, Chen C, Zou G, Lin G, Huang T, Hu R, Ran T, Han L, Zhang Q, Li Y, Zhao X
Hepatology international 2024 Jun;18(3):1040-1052
Hepatology international 2024 Jun;18(3):1040-1052
Hsa_circ_0004214 involved in the epithelial-mesenchymal transition induced by beryllium sulfate through modulating JAK-STAT signaling pathway.
Jin H, Liu Y, Lei Y, Li G, Huang L, Zhang Z
Toxicology research 2024 Jun;13(3):tfae067
Toxicology research 2024 Jun;13(3):tfae067
microRNA-125b-1-3p mediates autophagy via the RRAGD/mTOR/ULK1 signaling pathway and mitigates atherosclerosis progression.
Chen X, Cao Y, Guo Y, Liu J, Ye X, Li H, Zhang L, Feng W, Xian S, Yang Z, Wang L, Wang T
Cellular signalling 2024 Jun;118:111136
Cellular signalling 2024 Jun;118:111136
Bioactive compound schaftoside from Clinacanthus nutans attenuates acute liver injury by inhibiting ferroptosis through activation the Nrf2/GPX4 pathway.
Yu Y, Liang J, Yuan Z, Wang A, Liu X, Chen Y, Zhang M, Gao Y, Zhang H, Liu Y
Journal of ethnopharmacology 2024 Jun 28;328:118135
Journal of ethnopharmacology 2024 Jun 28;328:118135
Multiomic analysis of monocyte-derived alveolar macrophages in idiopathic pulmonary fibrosis.
Zhang M, Zhang J, Hu H, Zhou Y, Lin Z, Jing H, Sun B
Journal of translational medicine 2024 Jun 27;22(1):598
Journal of translational medicine 2024 Jun 27;22(1):598
Single-cell transcriptome profiling highlights the importance of telocyte, kallikrein genes, and alternative splicing in mouse testes aging.
Guo W, Zhang Z, Kang J, Gao Y, Qian P, Xie G
Scientific reports 2024 Jun 26;14(1):14795
Scientific reports 2024 Jun 26;14(1):14795
Improved Cell Adhesion on Self-Assembled Chiral Nematic Cellulose Nanocrystal Films.
Wang X, Xu H, Ning F, Duan S, Hu Y, Ding X, Xu FJ
Macromolecular rapid communications 2024 Jun 24;:e2400339
Macromolecular rapid communications 2024 Jun 24;:e2400339
Exosomal miR-17-5p derived from epithelial cells is involved in aberrant epithelium-fibroblast crosstalk and induces the development of oral submucosal fibrosis.
Xie C, Zhong L, Feng H, Wang R, Shi Y, Lv Y, Hu Y, Li J, Xiao D, Liu S, Chen Q, Tao Y
International journal of oral science 2024 Jun 20;16(1):48
International journal of oral science 2024 Jun 20;16(1):48
Nrf2 mediates the effects of shionone on silica-induced pulmonary fibrosis.
Wang G, Xie W, Deng L, Huang X, Sun M, Liu W, Tang S
Chinese medicine 2024 Jun 19;19(1):88
Chinese medicine 2024 Jun 19;19(1):88
Graphene Far-Infrared Irradiation Can Effectively Relieve the Blood Pressure Level of Rat Untr-HT in Primary Hypertension.
Lu G, Guo H, Zhang Y, Zhang M, Zhang T, Hu G, Zhang Q
International journal of molecular sciences 2024 Jun 18;25(12)
International journal of molecular sciences 2024 Jun 18;25(12)
Amelioration of NAFLD by sleeve gastrectomy-triggered hepatocyte regeneration in mice - experimental research.
Yu T, Ma X, Cheng Y, Wang Z, Zhang G, Ding H, Yin J, Wang Y, Hu S
International journal of surgery (London, England) 2024 Jun 1;110(6):3307-3325
International journal of surgery (London, England) 2024 Jun 1;110(6):3307-3325
Resistance exercise upregulates Irisin expression and suppresses myocardial fibrosis following myocardial infarction via activating AMPK-Sirt1 and inactivating TGFβ1-Smad2/3.
Li H, Qin S, Tang J, Wang T, Ren W, Di L, Bo W, Ma Y, Wu F, Xu Z, Song W, Cai M, Xi Y, Tian Z
Acta physiologica (Oxford, England) 2024 Jul;240(7):e14163
Acta physiologica (Oxford, England) 2024 Jul;240(7):e14163
The dual role of 20(S)-protopanaxadiol in alleviating pulmonary fibrosis through the gut-lung axis.
Ruan Y, Ren G, Wang M, Lv W, Shimizu K, Zhang C
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155699
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Jul;129:155699
Repair potential of self-assembling peptide hydrogel in a mouse model of anterior cruciate ligament reconstruction.
Fujino K, Yamamoto N, Yoshimura Y, Yokota A, Hirano Y, Neo M
Journal of experimental orthopaedics 2024 Jul;11(3):e12061
Journal of experimental orthopaedics 2024 Jul;11(3):e12061
Identification of signaling pathways that specify a subset of migrating enteric neural crest cells at the wavefront in mouse embryos.
Zhou B, Feng C, Sun S, Chen X, Zhuansun D, Wang D, Yu X, Meng X, Xiao J, Wu L, Wang J, Wang J, Chen K, Li Z, You J, Mao H, Yang S, Zhang J, Jiao C, Li Z, Yu D, Wu X, Zhu T, Yang J, Xiang L, Liu J, Chai T, Shen J, Mao CX, Hu J, Hao X, Xiong B, Zheng S, Liu Z, Feng J
Developmental cell 2024 Jul 8;59(13):1689-1706.e8
Developmental cell 2024 Jul 8;59(13):1689-1706.e8
Arctigenin induces activated HSCs quiescence via AMPK-PPARγ pathway to ameliorate liver fibrosis in mice.
Lv M, Chen S, Shan M, Si Y, Huang C, Chen J, Gong L
European journal of pharmacology 2024 Jul 5;974:176629
European journal of pharmacology 2024 Jul 5;974:176629
Puerarin enhances TFEB-mediated autophagy and attenuates ROS-induced pyroptosis after ischemic injury of random-pattern skin flaps.
Lai Y, Yang N, Shi D, Ma X, Huang Y, Lu J, Zhang X, Zhou H, Gao W, Mao C, Wang L
European journal of pharmacology 2024 Jul 5;974:176621
European journal of pharmacology 2024 Jul 5;974:176621
Loss of STARD13 contributes to aggressive phenotype transformation and poor prognosis in papillary thyroid carcinoma.
Zeng C, Li H, Liang W, Chen J, Zhang Y, Zhang H, Xiao H, Li Y, Guan H
Endocrine 2024 Jan;83(1):127-141
Endocrine 2024 Jan;83(1):127-141
Uric acid promotes interleukin-17 expression to cause kidney injury.
Yang L, He T, Yu Y
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23550
Journal of biochemical and molecular toxicology 2024 Jan;38(1):e23550
A responsive hydrogel modulates innate immune cascade fibrosis to promote ocular surface reconstruction after chemical injury.
Zhang J, Su L, Liu Z, Tang J, Zhang L, Li Z, Zhou D, Sun Z, Xi K, Lu P, Deng G
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
Journal of controlled release : official journal of the Controlled Release Society 2024 Jan;365:1124-1138
Chitosan-based oral nanoparticles as an efficient platform for kidney-targeted drug delivery in the treatment of renal fibrosis.
Zhang Q, Li Y, Wang S, Gu D, Zhang C, Xu S, Fang X, Li C, Wu H, Xiong W
International journal of biological macromolecules 2024 Jan;256(Pt 1):128315
International journal of biological macromolecules 2024 Jan;256(Pt 1):128315
A hyaluronic acid / chitosan composite functionalized hydrogel based on enzyme-catalyzed and Schiff base reaction for promoting wound healing.
Li J, Su J, Liang J, Zhang K, Xie M, Cai B, Li J
International journal of biological macromolecules 2024 Jan;255:128284
International journal of biological macromolecules 2024 Jan;255:128284
Overexpression of Corin Ameliorates Kidney Fibrosis through Inhibition of Wnt/β-Catenin Signaling in Mice.
Su X, Li S, Zhang Y, Tie X, Feng R, Guo X, Qiao X, Wang L
The American journal of pathology 2024 Jan;194(1):101-120
The American journal of pathology 2024 Jan;194(1):101-120
Melatonin inhibits fibroblast cell functions and hypertrophic scar formation by enhancing autophagy through the MT2 receptor-inhibited PI3K/Akt /mTOR signaling.
Dong Y, Cao X, Huang J, Hu Z, Chen C, Chen M, Long Q, Xu Z, Lv D, Rong Y, Luo S, Wang H, Deng W, Tang B
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Biochimica et biophysica acta. Molecular basis of disease 2024 Jan;1870(1):166887
Inhibition of TGFβ1 activation prevents radiation-induced lung fibrosis.
Yi M, Yuan Y, Ma L, Li L, Qin W, Wu B, Zheng B, Liao X, Hu G, Liu B
Clinical and translational medicine 2024 Jan;14(1):e1546
Clinical and translational medicine 2024 Jan;14(1):e1546
Quantitative Analysis of the Concentration of Trifluridine in Tumor Hypoxic Regions Using a Novel Platform Combining Functional Endoscopy and Mass Spectrometry.
Koganemaru S, Fuchigami H, Yamashita H, Morizono C, Sunakawa H, Kawazoe A, Nakamura Y, Kuboki Y, Shitara K, Yano T, Doi T, Yasunaga M
Clinical pharmacology and therapeutics 2024 Jan;115(1):62-70
Clinical pharmacology and therapeutics 2024 Jan;115(1):62-70
Metabolomics reveals that chronic restraint stress alleviates carbon tetrachloride-induced hepatic fibrosis through the INSR/PI3K/AKT/AMPK pathway.
Zhang S, Liu B, Huang L, Zhang R, An L, Liu Z
Journal of molecular medicine (Berlin, Germany) 2024 Jan;102(1):113-128
Journal of molecular medicine (Berlin, Germany) 2024 Jan;102(1):113-128
Diosmin ameliorates renal fibrosis through inhibition of inflammation by regulating SIRT3-mediated NF-κB p65 nuclear translocation.
Zhao WM, Li XL, Zhu Y, Shi R, Wang ZJ, Xiao JP, Wang DG
BMC complementary medicine and therapies 2024 Jan 9;24(1):29
BMC complementary medicine and therapies 2024 Jan 9;24(1):29
Menstrual blood-derived stem cells exosomal miR-let-7 to ameliorate pulmonary fibrosis through inhibiting ferroptosis by Sp3/HDAC2/Nrf2 signaling pathway.
Sun L, He X, Kong J, Yu H, Wang Y
International immunopharmacology 2024 Jan 5;126:111316
International immunopharmacology 2024 Jan 5;126:111316
Lactate accumulation induced by Akt2-PDK1 signaling promotes pulmonary fibrosis.
Sun Z, Ji Z, He W, Duan R, Qu J, Yu G
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23426
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Jan 31;38(2):e23426
MicroRNA miR-181d-5p regulates the MAPK signaling pathway by targeting mitogen-activated protein kinase 8 (MAPK8) to improve lupus nephritis.
Chai F, Peng H, Qin L, Liu C, Zeng Y, Wang R, Xu G, Wang R, Wei G, Huang H, Lan Y, Chen W, Wang C
Gene 2024 Jan 30;893:147961
Gene 2024 Jan 30;893:147961
The anti-liver fibrosis effect of Tibetan medicine (Qiwei Tiexie capsule) is related to the inhibition of NLRP3 inflammasome activation in vivo and in vitro.
Wang S, Ye F, Ren Q, Sun S, Xia W, Wang Z, Guo H, Li H, Zhang S, Lowe S, Chen M, Du Q, Weihong Li
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117283
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117283
Phthalides from the rhizome of Ligusticum chuanxiong Hort. attenuate diabetic nephropathy in mice.
Qi XY, Peng GC, Han QT, Yan J, Chen LZ, Wang T, Xu LT, Liu MJ, Xu ZP, Wang XN, Shen T
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117247
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117247
Quercetin inhibits mesothelial-mesenchymal transition and alleviates postoperative peritoneal adhesions by blocking the TGF-β1/PI3K/AKT pathway.
Li G, Ren Y, Li E, Deng K, Qu C, Zhang J, Zhang L, Wang X, Lian J, Zhou H, Wang Z, Shen T, Li X, Jiang Z
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117242
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117242
Self-assembled coating with a metal-polyphenolic network for intraocular lens modification to prevent posterior capsule opacification.
Wang Y, Wen C, Jing R, Yang Y, Qin Y, Qi T, Hu C, Bai X, Wu C, Pei C
Biomedical materials (Bristol, England) 2024 Jan 22;19(2)
Biomedical materials (Bristol, England) 2024 Jan 22;19(2)
The SIRT1/Nrf2 signaling pathway mediates the anti-pulmonary fibrosis effect of liquiritigenin.
Hua Q, Ren L
Chinese medicine 2024 Jan 18;19(1):12
Chinese medicine 2024 Jan 18;19(1):12
Phomopsterone B Alleviates Liver Fibrosis through mTOR-Mediated Autophagy and Apoptosis Pathway.
Peng ML, Zhang LJ, Luo Y, Xu SY, Long XM, Ao JL, Liao SG, Zhu QF, He X, Xu GB
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Molecules (Basel, Switzerland) 2024 Jan 15;29(2)
Rehmannia glutinosa Libosch and Cornus officinalis Sieb herb couple ameliorates renal interstitial fibrosis in CKD rats by inhibiting the TGF-β1/MAPK signaling pathway.
Zhu JH, Wang L, Ma ZX, Duan JA, Tao JH
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117039
Journal of ethnopharmacology 2024 Jan 10;318(Pt B):117039
Network pharmacology, molecular docking and experimental verification of the mechanism of huangqi-jixuecao herb pair in treatment of peritoneal fibrosis.
Dai H, Shan Y, Yu M, Wang F, Zhou Z, Sun J, Sheng L, Huang L, Sheng M
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116874
Journal of ethnopharmacology 2024 Jan 10;318(Pt A):116874
PRMT3 methylates HIF-1α to enhance the vascular calcification induced by chronic kidney disease.
Zhou G, Zhang C, Peng H, Su X, Huang Q, Zhao Z, Zhao G
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Molecular medicine (Cambridge, Mass.) 2024 Jan 10;30(1):8
Claudin-18.2 mediated interaction of gastric Cancer cells and Cancer-associated fibroblasts drives tumor progression.
Liu S, Zhang Z, Jiang L, Zhang M, Zhang C, Shen L
Cell communication and signaling : CCS 2024 Jan 10;22(1):27
Cell communication and signaling : CCS 2024 Jan 10;22(1):27
Hydrogen sulfide attenuates atherosclerosis induced by low shear stress by sulfhydrylating endothelium NFIL3 to restrain MEST mediated endothelial mesenchymal transformation.
Zhou K, Luo W, Gui DD, Ren Z, Wei DH, Liu LS, Li GH, Tang ZH, Xiong WH, Hu HJ, Jiang ZS
Nitric oxide : biology and chemistry 2024 Jan 1;142:47-57
Nitric oxide : biology and chemistry 2024 Jan 1;142:47-57
Oncostatin M/Oncostatin M Receptor Signal Induces Radiation-Induced Heart Fibrosis by Regulating SMAD4 in Fibroblast.
Xu P, Yi Y, Xiong L, Luo Y, Xie C, Luo D, Zeng Z, Liu A
International journal of radiation oncology, biology, physics 2024 Jan 1;118(1):203-217
International journal of radiation oncology, biology, physics 2024 Jan 1;118(1):203-217
Establishment of an immortalized cell line derived from human adenomyosis ectopic lesions.
Wang Z, Cui F, Chen Y, Liu H, Zhang Y, Shi Y, Zhang Y, Wang Y, Liang N, Xu L, Liu Y, Liu Z, Shi W
Tissue & cell 2024 Feb;86:102284
Tissue & cell 2024 Feb;86:102284
Costunolide attenuates high-fat diet-induced inflammation and oxidative stress in non-alcoholic fatty liver disease.
Wang J, Jin B, Chen Y, Chen Y, Zuo W, Huang L, Lin J, Jiang Y, Xie L, Lian X, Wang Y
Drug development research 2024 Feb;85(1):e22150
Drug development research 2024 Feb;85(1):e22150
IRF4 Participates in Pulmonary Fibrosis Induced by Silica Particles through Regulating Macrophage Polarization and Fibroblast Activation.
Jiao B, Zhang Q, Jin C, Yu H, Wu Q
Inflammation 2024 Feb;47(1):45-59
Inflammation 2024 Feb;47(1):45-59
hPMSCs Regulate the Level of TNF-α and IL-10 in Th1 Cells and Improve Hepatic Injury in a GVHD Mouse Model via CD73/ADO/Fyn/Nrf2 Axis.
Zhang H, Han K, Li H, Zhang J, Zhao Y, Wu Y, Wang B, Ma J, Luan X
Inflammation 2024 Feb;47(1):244-263
Inflammation 2024 Feb;47(1):244-263
Microplastics cause hepatotoxicity in diabetic mice by disrupting glucolipid metabolism via PP2A/AMPK/HNF4A and promoting fibrosis via the Wnt/β-catenin pathway.
Li X, Feng L, Kuang Q, Wang X, Yang J, Niu X, Gao L, Huang L, Luo P, Li L
Environmental toxicology 2024 Feb;39(2):1018-1030
Environmental toxicology 2024 Feb;39(2):1018-1030
An Injectable Composite Hydrogel of Verteporfin-Bonded Carboxymethyl Chitosan and Oxidized Sodium Alginate Facilitates Scarless Full-Thickness Skin Regeneration.
Yang JT, Wu D, Li J, Zhao C, Zhu L, Xu C, Xu N
Macromolecular bioscience 2024 Feb;24(2):e2300165
Macromolecular bioscience 2024 Feb;24(2):e2300165
Transcription factor c-Maf drives macrophages to promote hypertrophic scar formation.
Yang L, Song Y, Wang T, Cui Z, Wu J, Shi Y, Yu Z, Song B
Journal of cosmetic dermatology 2024 Feb;23(2):639-647
Journal of cosmetic dermatology 2024 Feb;23(2):639-647
BRG1 enhances porcine iPSC pluripotency through WNT/β-catenin and autophagy pathways.
Ren X, Xu J, Xue Q, Tong Y, Xu T, Wang J, Yang T, Chen Y, Shi D, Li X
Theriogenology 2024 Feb;215:10-23
Theriogenology 2024 Feb;215:10-23
Alleviative Effect of Lactoferrin Interventions Against the Hepatotoxicity Induced by Titanium Dioxide Nanoparticles.
Zhang W, Sun J, Liu F, Li S, Wang X, Su L, Liu G
Biological trace element research 2024 Feb;202(2):624-642
Biological trace element research 2024 Feb;202(2):624-642
Downregulation of TET2 Contributes to Nasal Polypogenesis Through Hypoxia-Inducible Factor 1α-Mediated Epithelial-to-Mesenchymal Transition.
Liu K, Xu Y
Clinical and experimental otorhinolaryngology 2024 Feb;17(1):64-77
Clinical and experimental otorhinolaryngology 2024 Feb;17(1):64-77
Identification of (E)-1-((1H-indol-3-yl)methylene)-4-substitute-thiosemicarbazones as potential anti-hepatic fibrosis agents.
Lin G, Zhong Y, Hu S, He F, Zhang Z, Li W, Hu H, Zeng JZ
Bioorganic chemistry 2024 Feb;143:107022
Bioorganic chemistry 2024 Feb;143:107022
Discovery of PRDM16-Mediated TRPA1 Induction as the Mechanism for Low Tubulo-Interstitial Fibrosis in Diabetic Kidney Disease.
Xu F, Jiang H, Li X, Pan J, Li H, Wang L, Zhang P, Chen J, Qiu S, Xie Y, Li Y, Zhang D, Dong Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306704
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Feb;11(7):e2306704
Wearable bioadhesive ultrasound shear wave elastography.
Liu HC, Zeng Y, Gong C, Chen X, Kijanka P, Zhang J, Genyk Y, Tchelepi H, Wang C, Zhou Q, Zhao X
Science advances 2024 Feb 9;10(6):eadk8426
Science advances 2024 Feb 9;10(6):eadk8426
The Upregulation of Leucine-Rich Repeat Containing 1 Expression Activates Hepatic Stellate Cells and Promotes Liver Fibrosis by Stabilizing Phosphorylated Smad2/3.
Wang Y, Li X, Guan X, Song Z, Liu H, Guan Z, Wang J, Zhu L, Zhang D, Zhao L, Xie P, Wei X, Shang N, Liu Y, Jin Z, Ji Z, Dai G
International journal of molecular sciences 2024 Feb 27;25(5)
International journal of molecular sciences 2024 Feb 27;25(5)
Galectin-3 is involved in inflammation and fibrosis in arteriogenic erectile dysfunction via the TLR4/MyD88/NF-κB pathway.
Wang G, Li R, Feng C, Li K, Liu S, Fu Q
Cell death discovery 2024 Feb 20;10(1):92
Cell death discovery 2024 Feb 20;10(1):92
Pro-ferroptotic signaling promotes arterial aging via vascular smooth muscle cell senescence.
Sun DY, Wu WB, Wu JJ, Shi Y, Xu JJ, Ouyang SX, Chi C, Shi Y, Ji QX, Miao JH, Fu JT, Tong J, Zhang PP, Zhang JB, Li ZY, Qu LF, Shen FM, Li DJ, Wang P
Nature communications 2024 Feb 16;15(1):1429
Nature communications 2024 Feb 16;15(1):1429
TXNIP deficiency attenuates renal fibrosis by modulating mTORC1/TFEB-mediated autophagy in diabetic kidney disease.
Du Y, Wu M, Song S, Bian Y, Shi Y
Renal failure 2024 Dec;46(1):2338933
Renal failure 2024 Dec;46(1):2338933
Krüppel-like factor 4 modulates the miR-101/COL10A1 axis to inhibit renal fibrosis after AKI by regulating epithelial-mesenchymal transition.
Zhao J, Wang X, Wu Y, Zhao C
Renal failure 2024 Dec;46(1):2316259
Renal failure 2024 Dec;46(1):2316259
Pachymic acid ameliorates bleomycin-induced pulmonary fibrosis through inhibiting endoplasmic reticulum stress in rats.
Li L, Jin RJ, Ji L
Environmental toxicology 2024 Dec;39(12):5382-5390
Environmental toxicology 2024 Dec;39(12):5382-5390
The mechanism of α2-macroglobulin against oxidative stress and promoting cell proliferation in intervertebral disc degeneration.
Liang H, Wang Y
Bioengineered 2024 Dec;15(1):2011638
Bioengineered 2024 Dec;15(1):2011638
TGFβ2 mediates oxidative stress-induced epithelial-to-mesenchymal transition of bladder smooth muscle.
Geng J, Zhang X, Zhang Y, Meng X, Sun J, Zhou B, Ma J
In vitro cellular & developmental biology. Animal 2024 Aug;60(7):793-804
In vitro cellular & developmental biology. Animal 2024 Aug;60(7):793-804
Lycorine relieves the CCl(4)-induced liver fibrosis mainly via the JAK2/STAT3 and PI3K/AKT signaling pathways.
Tang Y, Zhu Z, Li M, Gao L, Wu X, Chen J, Zhang Y, Zhao H, Xiao Z
Toxicology and applied pharmacology 2024 Aug;489:117017
Toxicology and applied pharmacology 2024 Aug;489:117017
Macroscopic and histological examination of human bridging veins.
Cheshire EC, Harris NC, Malcomson RDG, Amoroso JM, Moreton JE, Biggs MJP
Forensic science international 2024 Aug;361:112080
Forensic science international 2024 Aug;361:112080
Inhibition of Let-7b-5p maturation by LIN28A promotes thermal skin damage repair after burn injury.
Zhou S, Guo L, Cui X, Zhang X, Yang Y, Zhang M, Zhang P
Cellular signalling 2024 Aug;120:111217
Cellular signalling 2024 Aug;120:111217
Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer.
Jiang Y, Wang Y, Chen G, Sun F, Wu Q, Huang Q, Zeng D, Qiu W, Wang J, Yao Z, Liang B, Li S, Wu J, Huang N, Wang Y, Chen J, Zhai X, Huang L, Xu B, Yamamoto M, Tsukamoto T, Nomura S, Liao W, Shi M
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cell metabolism 2024 Aug 6;36(8):1806-1822.e11
Cryptotanshinone alleviates liver fibrosis via inhibiting STAT3/CPT1A-dependent fatty acid oxidation in hepatic stellate cells.
Li Z, Zheng Y, Zhang L, Xu E
Chemico-biological interactions 2024 Aug 25;399:111119
Chemico-biological interactions 2024 Aug 25;399:111119
The antihypertensive effect of Alizarin is achieved by activating VEGFR2/eNOS pathway, attenuating oxidative stress-induced mitochondrial damage and premature senescence.
Qian YW, Guo YQ, Li YL, Wang Y, Guo S, Niu QQ, Zhu ML, Li P
Life sciences 2024 Aug 15;351:122862
Life sciences 2024 Aug 15;351:122862
Generation of human induced pluripotent stem cell line from a patient with restrictive cardiomyopathy.
Li J, Jiang J, Ye L, Lian Z, Gong H, Lei W, Dai Y, Hu S
Stem cell research 2024 Apr;76:103370
Stem cell research 2024 Apr;76:103370
Endothelial H(2)S-AMPK dysfunction upregulates the angiocrine factor PAI-1 and contributes to lung fibrosis.
Chen X, Wang H, Wu C, Li X, Huang X, Ren Y, Pu Q, Cao Z, Tang X, Ding BS
Redox biology 2024 Apr;70:103038
Redox biology 2024 Apr;70:103038
Exosomes derived from bone marrow mesenchymal stem cells alleviate biliary ischemia reperfusion injury in fatty liver transplantation by inhibiting ferroptosis.
Tian X, Wu L, Li X, Zheng W, Zuo H, Song H
Molecular and cellular biochemistry 2024 Apr;479(4):881-894
Molecular and cellular biochemistry 2024 Apr;479(4):881-894
DsbA-L ameliorates renal aging and renal fibrosis by maintaining mitochondrial homeostasis.
Yang M, Liu Y, Luo SL, Liu CB, Jiang N, Li CR, Zhao H, Han YC, Chen W, Li L, Sun L
Acta pharmacologica Sinica 2024 Apr;45(4):777-789
Acta pharmacologica Sinica 2024 Apr;45(4):777-789
BMSC-derived Exosomes Ameliorate Peritoneal Dialysis-associated Peritoneal Fibrosis via the Mir-27a-3p/TP53 Pathway.
Zhao JL, Zhao L, Zhan QN, Liu M, Zhang T, Chu WW
Current medical science 2024 Apr;44(2):333-345
Current medical science 2024 Apr;44(2):333-345
Bone morphogenetic protein 6 (BMP6) antagonises experimental proliferative vitreoretinopathy established by TGF-β2 stimulation in retinal pigment epithelial cells through modulation of the p38 and JNK MAPK pathways.
Liu X, Liu M, Chen L
Cell and tissue research 2024 Apr;396(1):103-117
Cell and tissue research 2024 Apr;396(1):103-117
M2 macrophage-derived paracrine factor TNFSF13 affects the fibrogenic alterations in endothelial cells and cardiac fibroblasts by mediating the NF-κB and Akt pathway.
Tan X, Wang J, Liu X, Xie G, Ouyang F
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23707
Journal of biochemical and molecular toxicology 2024 Apr;38(4):e23707
Lipin-1 deficiency deteriorates defect of fatty acid β-oxidation and lipid-related kidney damage in diabetic kidney disease.
Lin S, Wang L, Jia Y, Sun Y, Qiao P, Quan Y, Liu J, Hu H, Yang B, Zhou H
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Translational research : the journal of laboratory and clinical medicine 2024 Apr;266:1-15
Antler thymosin β10 reduces liver fibrosis via inhibiting TGF-β1/SMAD pathway.
Zhang G, Shi L, Li J, Ren J, Wang D, Guo X, Guo Q, Li C
International journal of biological macromolecules 2024 Apr;264(Pt 1):130502
International journal of biological macromolecules 2024 Apr;264(Pt 1):130502
Polyvinyl alcohol/carboxymethyl chitosan-based hydrogels loaded with taxifolin liposomes promote diabetic wound healing by inhibiting inflammation and regulating autophagy.
Ding Q, Liu X, Liu X, Chai G, Wang N, Ma S, Zhang L, Zhang S, Yang J, Wang Y, Shen L, Ding C, Liu W
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
International journal of biological macromolecules 2024 Apr;263(Pt 1):130226
Antibiotic bone cement accelerates diabetic foot wound healing: Elucidating the role of ROCK1 protein expression.
Yang C, Wang D
International wound journal 2024 Apr;21(4):e14590
International wound journal 2024 Apr;21(4):e14590
Cellular nucleic acid binding protein facilitates cardiac repair after myocardial infarction by activating β-catenin signaling.
Du C, Zhao S, Shan T, Han X, Jiang Q, Chen J, Gu L, Wei T, Yang T, Wang S, Wang H, Guo X, Wang L
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Journal of molecular and cellular cardiology 2024 Apr;189:66-82
Icariin alleviates diabetic renal interstitial fibrosis aggravation by inhibiting miR-320a-3p targeting BMP6.
Wang K, Hou M, Qiao C, Duan Y, Tao R, Wang X, Xiao K, Liu S, Zhao H, Wang J, Jia Z, Ding X
Journal of pharmacological sciences 2024 Apr;154(4):316-325
Journal of pharmacological sciences 2024 Apr;154(4):316-325
CXCL4/CXCR3 axis regulates cardiac fibrosis by activating TGF-β1/Smad2/3 signaling in mouse viral myocarditis.
Wei J, Wang DF, Cui CC, Tan JJ, Peng MY, Lu HX
Immunity, inflammation and disease 2024 Apr;12(4):e1237
Immunity, inflammation and disease 2024 Apr;12(4):e1237
Low-Frequency Ultrasound Sensitive Piezo1 Channels Regulate Keloid-Related Characteristics of Fibroblasts.
Jiang Z, Chen Z, Xu Y, Li H, Li Y, Peng L, Shan H, Liu X, Wu H, Wu L, Jian D, Su J, Chen X, Chen Z, Zhao S
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2305489
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2024 Apr;11(14):e2305489
PI3Kδ Mediates Fibrosis by Patient-Derived Vitreous.
Liu D, Yan B, Yin Y, Chen F, Guo C, Li Q, Liu J, Pu L, Wu W, Luo J
Laboratory investigation; a journal of technical methods and pathology 2024 Apr;104(4):102026
Laboratory investigation; a journal of technical methods and pathology 2024 Apr;104(4):102026
NBR1-p62-Nrf2 mediates the anti-pulmonary fibrosis effects of protodioscin.
Zeng Q, Wen BB, Liu X, Luo YY, Hu ZG, Huang L, Zhang XH, Huang XT, Zhou TT, Sang XX, Luo YY, Xiong DY, Luo ZQ, Liu W, Tang SY
Chinese medicine 2024 Apr 8;19(1):60
Chinese medicine 2024 Apr 8;19(1):60
Global proteomic analysis reveals lysine succinylation is involved in the pathogenesis of hypertrophic scar.
Qiu K, Tian Y, Guo C, Liu O, Shi Y, Liu D, Luo T
Journal of proteomics 2024 Apr 30;298:105155
Journal of proteomics 2024 Apr 30;298:105155
DEC1 is involved in circadian rhythm disruption-exacerbated pulmonary fibrosis.
Chen SJ, Yu F, Feng X, Li Q, Jiang YH, Zhao LQ, Cheng PP, Wang M, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ye H, Ma WL
Cell communication and signaling : CCS 2024 Apr 26;22(1):245
Cell communication and signaling : CCS 2024 Apr 26;22(1):245
ACAT2 suppresses the ubiquitination of YAP1 to enhance the proliferation and metastasis ability of gastric cancer via the upregulation of SETD7.
Zhang M, Cai F, Guo J, Liu S, Ma G, Cai M, Zhang R, Deng J
Cell death & disease 2024 Apr 26;15(4):297
Cell death & disease 2024 Apr 26;15(4):297
SirT7-mediated transcription of fascin in hyperglycemic glomerular endothelial cells contributes to EndMT in diabetic nephropathy.
Wu M, Hao Y, Wu X, Zhu M, Chen X, Qi J, Yu Z, Xu H
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):586-596
Acta biochimica et biophysica Sinica 2024 Apr 25;56(4):586-596
Jin-Gui-Shen-Qi Wan alleviates fibrosis in mouse diabetic nephropathy via MHC class II.
Liang D, Liu L, Qi Y, Nan F, Huang J, Tang S, Tang J, Chen N
Journal of ethnopharmacology 2024 Apr 24;324:117745
Journal of ethnopharmacology 2024 Apr 24;324:117745
Leech extract alleviates idiopathic pulmonary fibrosis by TGF-β1/Smad3 signaling pathway.
Zhang Y, Lu YB, Zhu WJ, Gong XX, Qian R, Lu YJ, Li Y, Yao WF, Bao BH, Zhang Y, Zhang L, Cheng FF
Journal of ethnopharmacology 2024 Apr 24;324:117737
Journal of ethnopharmacology 2024 Apr 24;324:117737
Baicalein alleviates intrahepatic cholestasis by regulating bile acid metabolism via an FXR-dependent manner.
Huang W, Qian Y, Lin J, Wang F, Kong X, Tan W
Biochemical and biophysical research communications 2024 Apr 23;705:149670
Biochemical and biophysical research communications 2024 Apr 23;705:149670
NLRP3 inflammasome-mediated premature immunosenescence drives diabetic vascular aging dependent on the induction of perivascular adipose tissue dysfunction.
Tai GJ, Ma YJ, Feng JL, Li JP, Qiu S, Yu QQ, Liu RH, Wankumbu SC, Wang X, Li XX, Xu M
Cardiovascular research 2024 Apr 21;
Cardiovascular research 2024 Apr 21;
AP39 through AMPK-ULK1-FUNDC1 pathway regulates mitophagy, inhibits pyroptosis, and improves doxorubicin-induced myocardial fibrosis.
Zhao J, Yang T, Yi J, Hu H, Lai Q, Nie L, Liu M, Chu C, Yang J
iScience 2024 Apr 19;27(4):109321
iScience 2024 Apr 19;27(4):109321
Human Umbilical Cord Mesenchymal Stromal Cell-Derived Exosomes Alleviate Hypoxia-Induced Pulmonary Arterial Hypertension in Mice Via Macrophages.
Liu H, Zhang Q, Liu C, Zhang Y, Wang Y, Huang P, Ma L, Ge R
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):329-345
Stem cells (Dayton, Ohio) 2024 Apr 15;42(4):329-345
Improving impact of heparan sulfate on the endothelial glycocalyx abnormalities in atherosclerosis as revealed by glycan-protein interactome.
Chen Q, Xu X, Xie S, Sheng A, Han N, Tian Z, Wang X, Li F, Linhardt RJ, Zhang F, Jin L, Zhang Q, Chi L
Carbohydrate polymers 2024 Apr 15;330:121834
Carbohydrate polymers 2024 Apr 15;330:121834
Incorporating machine learning and PPI networks to identify mitochondrial fission-related immune markers in abdominal aortic aneurysms.
Liu YJ, Li R, Xiao D, Yang C, Li YL, Chen JL, Wang Z, Zhao XG, Shan ZG
Heliyon 2024 Apr 15;10(7):e27989
Heliyon 2024 Apr 15;10(7):e27989
FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation.
Li Y, Zuo C, Wu X, Ding Y, Wei Y, Chen S, Lu X, Xu J, Liu S, Zhou G, Cai L
Cell death & disease 2024 Apr 13;15(4):263
Cell death & disease 2024 Apr 13;15(4):263
Patient-Derived Exosomes as siRNA Carriers in Ovarian Cancer Treatment.
Shimizu A, Sawada K, Kobayashi M, Oi Y, Oride T, Kinose Y, Kodama M, Hashimoto K, Kimura T
Cancers 2024 Apr 12;16(8)
Cancers 2024 Apr 12;16(8)
Liquiritigenin Attenuated Collagen-Induced Arthritis and Cardiac Complication via Inflammation and Fibrosis Inhibition in Mice.
Ning X, Ni Y, Cao J, Zhang H
Chemical & pharmaceutical bulletin 2023;71(4):269-276
Chemical & pharmaceutical bulletin 2023;71(4):269-276
Trimethylamine N-oxide Promotes Atherosclerosis by Regulating Low-Density Lipoprotein-Induced Autophagy in Vascular Smooth Muscle Cells Through PI3K/AKT/mTOR Pathway.
Shi G, Zeng L, Shi J, Chen Y
International heart journal 2023;64(3):462-469
International heart journal 2023;64(3):462-469
Isolation and Cultivation of Vascular Smooth Muscle Cells from the Mouse Circle of Willis.
Chang W, Li Y, Liu F, Zang K, Zhang P, Qu S, Zhao J, Xue J
Journal of vascular research 2023;60(4):234-244
Journal of vascular research 2023;60(4):234-244
Propofol improves ischemia reperfusion-induced liver fibrosis by regulating lncRNA HOXA11-AS.
Luo J, Liu J, Mou Y, Luo F, Liao Q, Liao Y
The Journal of toxicological sciences 2023;48(6):345-354
The Journal of toxicological sciences 2023;48(6):345-354
Chlorogenic Acid Inhibited Epithelial-Mesenchymal Transition to Treat Pulmonary Fibrosis through Modulating Autophagy.
Mao X, Xie X, Ma J, Wei Y, Huang Z, Wang T, Zhu J, Wang Y, Zhao H, Hua J
Biological & pharmaceutical bulletin 2023;46(7):929-938
Biological & pharmaceutical bulletin 2023;46(7):929-938
Indirubin alleviates CCl(4)-induced liver fibrosis by regulation of TGF-β-mediated signaling pathways.
Li X, Yao Y, Wei L
Iranian journal of basic medical sciences 2023;26(9):1047-1052
Iranian journal of basic medical sciences 2023;26(9):1047-1052
Up-regulated SPP1 increases the risk from IPF to lung cancer via activating the pro-tumor macrophages.
Chen T, Guo J, Ai L, Wang Y, Wang Y, Chen B, Liu M, Zhuang S, Liu K, Zhao Z, Liang H, Gu Y
Computational and structural biotechnology journal 2023;21:5751-5764
Computational and structural biotechnology journal 2023;21:5751-5764
miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding.
Wen J, Tang B, Guo L, Chen W, Tang X
International journal of hypertension 2023;2023:9497716
International journal of hypertension 2023;2023:9497716
hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts.
Wang Y, Zhang Y, Lu B, Xi J, Ocansey DKW, Mao F, Hao D, Yan Y
Stem cells international 2023;2023:2828981
Stem cells international 2023;2023:2828981
FAT10 Silencing Prevents Liver Fibrosis through Regulating SIRT1 Expression in Hepatic Stellate Cells.
Zheng W, Guan F, Xu G, Yu Y, Xiao J, Huang X
International journal of medical sciences 2023;20(4):557-565
International journal of medical sciences 2023;20(4):557-565
Sarcoma protein kinase inhibition alleviates liver fibrosis by promoting hepatic stellate cells ferroptosis.
Cheng Z, Zhang X, Chen P, Wang H, Wang K, Shen Y
Open life sciences 2023;18(1):20220781
Open life sciences 2023;18(1):20220781
Adiponectin inhibits TGF-β1-induced skin fibroblast proliferation and phenotype transformation via the p38 MAPK signaling pathway.
Wang X, Yan X, Huang F, Wu L
Open life sciences 2023;18(1):20220679
Open life sciences 2023;18(1):20220679
Exosome Derived from Mesenchymal Stem Cells Alleviates Hypertrophic Scar by Inhibiting the Fibroblasts via TNFSF-13/HSPG2 Signaling Pathway.
Zhang H, Zang C, Zhao W, Zhang L, Liu R, Feng Z, Wu J, Cui R
International journal of nanomedicine 2023;18:7047-7063
International journal of nanomedicine 2023;18:7047-7063
Identification and Characterization of a Novel Nanobody Against Human CTGF to Reveal Its Antifibrotic Effect in an in vitro Model of Liver Fibrosis.
Liu R, Zhu M, Chen J, Gai J, Huang J, Zhou Y, Wan Y, Tu C
International journal of nanomedicine 2023;18:5407-5422
International journal of nanomedicine 2023;18:5407-5422
Glycosylation-Engineered Platelet Membrane-Coated Interleukin 10 Nanoparticles for Targeted Inhibition of Vascular Restenosis.
Li F, Rong Z, Chen T, Wang P, Di X, Ni L, Liu C
International journal of nanomedicine 2023;18:5011-5030
International journal of nanomedicine 2023;18:5011-5030
Co-Delivery Nanomicelles for Potentiating TNBC Immunotherapy by Synergetically Reshaping CAFs-Mediated Tumor Stroma and Reprogramming Immunosuppressive Microenvironment.
Zhang Y, Han X, Wang K, Liu D, Ding X, Hu Z, Wang J
International journal of nanomedicine 2023;18:4329-4346
International journal of nanomedicine 2023;18:4329-4346
Irisin Ameliorates Renal Tubulointerstitial Fibrosis by Regulating the Smad4/β-Catenin Pathway in Diabetic Mice.
Yang Z, Wei J, Wang Y, Du Y, Song S, Li J, Su Z, Shi Y, Wu H
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:1577-1593
Diabetes, metabolic syndrome and obesity : targets and therapy 2023;16:1577-1593
GLIS2 Prevents Hepatic Fibrosis by Competitively Binding HDAC3 to Inhibit Hepatic Stellate Cell Activation.
Zhang H, Zhou P, Xing W, Chen L, Zhou Y, Yang H, Fu K, Liu Z
Cellular and molecular gastroenterology and hepatology 2023;15(2):355-372
Cellular and molecular gastroenterology and hepatology 2023;15(2):355-372
Mannan-Binding Lectin Reduces Epithelial-Mesenchymal Transition in Pulmonary Fibrosis via Inactivating the Store-Operated Calcium Entry Machinery.
Liu Y, Xie X, Wang P, Luo J, Chen Y, Xu Q, Zhou J, Lu X, Zhao J, Chen Z, Zuo D
Journal of innate immunity 2023;15(1):37-49
Journal of innate immunity 2023;15(1):37-49
A comprehensive cuproptosis score and associated gene signatures reveal prognostic and immunological features of idiopathic pulmonary fibrosis.
Jing C, Fu R, Liu X, Zang G, Zhu X, Wang C, Zhang W
Frontiers in immunology 2023;14:1268141
Frontiers in immunology 2023;14:1268141
Four novel mutations identification in 17 beta-hydroxysteroid dehydrogenase-3 deficiency and our clinical experience: possible benefits of early treatment.
Wang Y, Xu Y, Zhang H, Yin D, Pan Y, He X, Li S, Cheng Z, Zhu G, Zhao T, Huang H, Zhu M
Frontiers in endocrinology 2023;14:1267967
Frontiers in endocrinology 2023;14:1267967
Tangeretin attenuates bleomycin-induced pulmonary fibrosis by inhibiting epithelial-mesenchymal transition via the PI3K/Akt pathway.
Li J, Wei Q, Song K, Wang Y, Yang Y, Li M, Yu J, Su G, Peng L, Fu B, Yi P
Frontiers in pharmacology 2023;14:1247800
Frontiers in pharmacology 2023;14:1247800
The influence of angiopoietin-like protein 3 on macrophages polarization and its effect on the podocyte EMT in diabetic nephropathy.
Ma Y, Chen Y, Xu H, Du N
Frontiers in immunology 2023;14:1228399
Frontiers in immunology 2023;14:1228399
APOC1 exacerbates renal fibrosis through the activation of the NF-κB signaling pathway in IgAN.
Yu K, Ding L, An X, Yang Y, Zhang X, Li L, Wang C, Bai F, Yang X
Frontiers in pharmacology 2023;14:1181435
Frontiers in pharmacology 2023;14:1181435
The role of the SGK3/TOPK signaling pathway in the transition from acute kidney injury to chronic kidney disease.
Shu H, Wang Y, Zhang H, Dong Q, Sun L, Tu Y, Liao Q, Feng L, Yao L
Frontiers in pharmacology 2023;14:1169054
Frontiers in pharmacology 2023;14:1169054
Exercise intervention improves mitochondrial quality in non-alcoholic fatty liver disease zebrafish.
Zou YY, Tang XB, Chen ZL, Liu B, Zheng L, Song MY, Xiao Q, Zhou ZQ, Peng XY, Tang CF
Frontiers in endocrinology 2023;14:1162485
Frontiers in endocrinology 2023;14:1162485
Apolipoprotein A-I attenuates peritoneal fibrosis associated with peritoneal dialysis by inhibiting oxidative stress and inflammation.
Lu J, Gao J, Sun J, Wang H, Sun H, Huang Q, Zhang Y, Zhong S
Frontiers in pharmacology 2023;14:1106339
Frontiers in pharmacology 2023;14:1106339
IL-12α deficiency attenuates pressure overload-induced cardiac inflammation, hypertrophy, dysfunction, and heart failure progression.
Bhattarai U, He X, Xu R, Liu X, Pan L, Sun Y, Chen JX, Chen Y
Frontiers in immunology 2023;14:1105664
Frontiers in immunology 2023;14:1105664
Aqueous extract of Amydrium sinense (Engl.) H. Li alleviates hepatic fibrosis by suppressing hepatic stellate cell activation through inhibiting Stat3 signaling.
Li J, Wu B, Zeng L, Lin Y, Chen Q, Wang H, An L, Zhang J, Chen S, Huang J, Zhan R, Zhang G
Frontiers in pharmacology 2023;14:1101703
Frontiers in pharmacology 2023;14:1101703
A strategy of local hydrogen capture and catalytic hydrogenation for enhanced therapy of chronic liver diseases.
Tao G, Liu F, Jin Z, Liu B, Wang H, Li D, Tang W, Chen Y, He Q, Qin S
Theranostics 2023;13(8):2455-2470
Theranostics 2023;13(8):2455-2470
Primary extra-gastrointestinal stromal tumor of retroperitoneum: Clinicopathologic characteristics and prognosis of six cases.
Lin J, Liao W, Wang J, Li W, Tang X, Li H, Yi X, Lu X, Chen Z, Zhu B, Feng X, Diao D
Frontiers in oncology 2023;13:1033598
Frontiers in oncology 2023;13:1033598
S-propargyl-cysteine promotes the stability of atherosclerotic plaque via maintaining vascular muscle contractile phenotype.
Ping L, Zhi-Ming L, Bi-Shan Z, Lei Z, Bo Y, Yi-Chun Z, Ming-Jie W
Frontiers in cell and developmental biology 2023;11:1291170
Frontiers in cell and developmental biology 2023;11:1291170
Effect of stem cell conditional medium-loading adhesive hydrogel on TGF-β1-induced endometrial stromal cell fibrosis.
Zhu Y, Wang T, Bao MJ, Qu XH, Li ZM
Frontiers in bioengineering and biotechnology 2023;11:1168136
Frontiers in bioengineering and biotechnology 2023;11:1168136
Engineered exosomes derived from miR-132-overexpresssing adipose stem cells promoted diabetic wound healing and skin reconstruction.
Ge L, Wang K, Lin H, Tao E, Xia W, Wang F, Mao C, Feng Y
Frontiers in bioengineering and biotechnology 2023;11:1129538
Frontiers in bioengineering and biotechnology 2023;11:1129538
Ketogenic diet alleviates renal fibrosis in mice by enhancing fatty acid oxidation through the free fatty acid receptor 3 pathway.
Qiu Y, Hu X, Xu C, Lu C, Cao R, Xie Y, Yang J
Frontiers in nutrition 2023;10:1127845
Frontiers in nutrition 2023;10:1127845
Preclinical evaluation of tolvaptan and salsalate combination therapy in a Pkd1-mouse model.
Song X, Leonhard WN, Kanhai AA, Steinberg GR, Pei Y, Peters DJM
Frontiers in molecular biosciences 2023;10:1058825
Frontiers in molecular biosciences 2023;10:1058825
Integrative analysis of cancer-associated fibroblast signature in gastric cancer.
Zhao Z, Mak TK, Shi Y, Li K, Huo M, Zhang C
Heliyon 2023 Sep;9(9):e19217
Heliyon 2023 Sep;9(9):e19217
Knockdown of AK142426 suppresses M2 macrophage polarization and inflammation in peritoneal fibrosis via binding to c-Jun.
Shao Q, Jiang C, Zhang Q, Liu J, Jin B, Zhao M, Xia Y
The journal of gene medicine 2023 Sep;25(9):e3524
The journal of gene medicine 2023 Sep;25(9):e3524
SIRT3 regulates mitophagy in liver fibrosis through deacetylation of PINK1/NIPSNAP1.
Li R, Wang Z, Wang Y, Sun R, Zou B, Tian X, Liu D, Zhao X, Zhou J, Zhao Y, Yao J
Journal of cellular physiology 2023 Sep;238(9):2090-2102
Journal of cellular physiology 2023 Sep;238(9):2090-2102
AP39 inhibits ferroptosis by inhibiting mitochondrial autophagy through the PINK1/parkin pathway to improve myocardial fibrosis with myocardial infarction.
Yang T, Yang Q, Lai Q, Zhao J, Nie L, Liu S, Yang J, Chu C
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115195
A novel onco-cardiological mouse model of lung cancer-induced cardiac dysfunction and its application in identifying potential roles of tRNA-derived small RNAs.
Wu Q, Zou S, Liu W, Liang M, Chen Y, Chang J, Liu Y, Yu X
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115117
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Sep;165:115117
miR-32-5p induces hepatic steatosis and hyperlipidemia by triggering de novo lipogenesis.
Wang YD, Wu LL, Mai YN, Wang K, Tang Y, Wang QY, Li JY, Jiang LY, Liao ZZ, Hu C, Wang YY, Liu JJ, Liu JH, Xiao XH
Metabolism: clinical and experimental 2023 Sep;146:155660
Metabolism: clinical and experimental 2023 Sep;146:155660
SGLT2 inhibitor empagliflozin downregulates miRNA-34a-5p and targets GREM2 to inactivate hepatic stellate cells and ameliorate non-alcoholic fatty liver disease-associated fibrosis.
Shen Y, Cheng L, Xu M, Wang W, Wan Z, Xiong H, Guo W, Cai M, Xu F
Metabolism: clinical and experimental 2023 Sep;146:155657
Metabolism: clinical and experimental 2023 Sep;146:155657
Milk-derived exosomes carrying siRNA-KEAP1 promote diabetic wound healing by improving oxidative stress.
Xiang X, Chen J, Jiang T, Yan C, Kang Y, Zhang M, Xiang K, Guo J, Jiang G, Wang C, XiangXu, Yang X, Chen Z
Drug delivery and translational research 2023 Sep;13(9):2286-2296
Drug delivery and translational research 2023 Sep;13(9):2286-2296
Celastrol attenuates diabetic nephropathy by upregulating SIRT1-mediated inhibition of EZH2related wnt/β-catenin signaling.
Tang Y, Wan F, Tang X, Lin Y, Zhang H, Cao J, Yang R
International immunopharmacology 2023 Sep;122:110584
International immunopharmacology 2023 Sep;122:110584
Axitinib attenuates the progression of liver fibrosis by restoring mitochondrial function.
Li H, Zhang R, Hu Y, Li J, Yang Y, Wu D, Gu X, Zhang F, Zhou H, Yang C
International immunopharmacology 2023 Sep;122:110555
International immunopharmacology 2023 Sep;122:110555
Geniposide alleviated bile acid-associated NLRP3 inflammasome activation by regulating SIRT1/FXR signaling in bile duct ligation-induced liver fibrosis.
Qin T, Hasnat M, Wang Z, Hassan HM, Zhou Y, Yuan Z, Zhang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154971
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154971
Mammalian cleavage factor 25 targets KLF14 to inhibit hepatic stellate cell activation and liver fibrosis.
Chen X, Shi W, Zhu L, Zhou X, Wang Y
Cellular signalling 2023 Sep;109:110752
Cellular signalling 2023 Sep;109:110752
HMGA2 knockdown alleviates the progression of nonalcoholic fatty liver disease (NAFLD) by downregulating SNAI2 expression.
Sun J, Jin X, Zhang X, Zhang B
Cellular signalling 2023 Sep;109:110741
Cellular signalling 2023 Sep;109:110741
TP53RK Drives the Progression of Chronic Kidney Disease by Phosphorylating Birc5.
Wu M, Jin Q, Xu X, Fan J, Chen W, Miao M, Gu R, Zhang S, Guo Y, Huang S, Zhang Y, Zhang A, Jia Z
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301753
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Sep;10(25):e2301753
FNDC5 inhibits autophagy of bone marrow mesenchymal stem cells and promotes their survival after transplantation by downregulating Sp1.
Wei H, Liu S, Wang T, Li Y, Liu K, Guo Q, Li L
Cell death discovery 2023 Sep 6;9(1):336
Cell death discovery 2023 Sep 6;9(1):336
NDUFC2 deficiency exacerbates endothelial mesenchymal transformation during ischemia-reperfusion via NLRP3.
Chen J, Liu X, Bi R, Liu P, Gong W
Neuroreport 2023 Sep 6;34(13):670-676
Neuroreport 2023 Sep 6;34(13):670-676
Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation.
Liu J, Chen Y, Chen H, Wang Y, Li D, Zhang Q, Chai L, Qiu Y, Zhang J, Shen N, Wang Q, Wang J, Li M
Respiratory research 2023 Sep 6;24(1):216
Respiratory research 2023 Sep 6;24(1):216
Exosomal miR-17-5p from human embryonic stem cells prevents pulmonary fibrosis by targeting thrombospondin-2.
Liu Q, Bi Y, Song S, Zhu K, Qiao X, Wang H, Ji G
Stem cell research & therapy 2023 Sep 4;14(1):234
Stem cell research & therapy 2023 Sep 4;14(1):234
The effects of Shikonin on the hypertrophic scar of rabbit ears via the TLR4/NF-κB signaling pathway.
Liu C, Zhang H, Cui X, Wang S, Zhou Q
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Sep 30;69(9):161-166
Cellular and molecular biology (Noisy-le-Grand, France) 2023 Sep 30;69(9):161-166
Curcumin ameliorates focal segmental glomerulosclerosis by inhibiting apoptosis and oxidative stress in podocytes.
Zhang H, Dong QQ, Shu HP, Tu YC, Liao QQ, Yao LJ
Archives of biochemistry and biophysics 2023 Sep 15;746:109728
Archives of biochemistry and biophysics 2023 Sep 15;746:109728
Dendrobium officinale Kimura & Migo polysaccharide inhibits hyperglycaemia-induced kidney fibrosis via the miRNA-34a-5p/SIRT1 signalling pathway.
Huang C, Yu J, Da J, Dong R, Dai L, Yang Y, Deng Y, Yuan J
Journal of ethnopharmacology 2023 Sep 15;313:116601
Journal of ethnopharmacology 2023 Sep 15;313:116601
The alcohol extracts of Sceptridium ternatum (Thunb.) Lyon exert anti-pulmonary fibrosis effect through targeting SETDB1/STAT3/p-STAT3 signaling.
Zou X, Huang Z, Zhan Z, Yuan M, Zhang Y, Liu T, Hu X, Fan W, Chen P, Qin H, Zhang S, Xia Y, Zheng S, Pan Z, Huang P
Journal of ethnopharmacology 2023 Sep 15;313:116520
Journal of ethnopharmacology 2023 Sep 15;313:116520
The effect of GelDex-S58 hydrogel on anti-conjunctival scarring after glaucoma filtration surgery.
Lin Y, Luo W, Jiang B, Lin Q, Tang M, Li X, Xie L
iScience 2023 Sep 15;26(9):107633
iScience 2023 Sep 15;26(9):107633
Selective inhibition of glycolysis in hepatic stellate cells and suppression of liver fibrogenesis with vitamin A-derivative decorated camptothecin micelles.
Xiang L, Wang X, Jiao Q, Shao Y, Luo R, Zhang J, Zheng X, Zhou S, Chen Y
Acta biomaterialia 2023 Sep 15;168:497-514
Acta biomaterialia 2023 Sep 15;168:497-514
PRDX1 Cys52Ser variant alleviates nonalcoholic steatohepatitis by reducing inflammation in mice.
Bai Z, Yin W, Liu R, Tang M, Shi X, Luo C, Xie X
Molecular metabolism 2023 Oct;76:101789
Molecular metabolism 2023 Oct;76:101789
Chronic β-adrenergic stress contributes to cardiomyopathy in rodents with collagen-induced arthritis.
Zhu ZD, Zhang M, Wang Z, Jiang CR, Huang CJ, Cheng HJ, Guan QY, Su TT, Wang MM, Gao Y, Wu HF, Wei W, Han YS, Wang QT
Acta pharmacologica Sinica 2023 Oct;44(10):1989-2003
Acta pharmacologica Sinica 2023 Oct;44(10):1989-2003
PDK4 facilitates fibroblast functions and diabetic wound healing through regulation of HIF-1α protein stability and gene expression.
Ma Z, Mo R, Yang P, Ding Y, Zhang H, Dong Z, Chen Y, Tan Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23215
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Oct;37(10):e23215
Human-Induced Hepatocytes-Derived Extracellular Vesicles Ameliorated Liver Fibrosis in Mice Via Suppression of TGF-β1/Smad Signaling and Activation of Nrf2/HO-1 Signaling.
Liu W, Wu J, Cao H, Ma C, Wu Z, Tian Y, Ma C, Qiu H, Pan G
Stem cells and development 2023 Oct;32(19-20):638-651
Stem cells and development 2023 Oct;32(19-20):638-651
Niclosamide inhibits TGF-β1-induced fibrosis of human Tenon's fibroblasts by regulating the MAPK-ERK1/2 pathway.
Zhang L, Li W, Liu X, Guo J, Wu X, Wang J
Experimental eye research 2023 Oct;235:109628
Experimental eye research 2023 Oct;235:109628
Myeloid-specific deletion of Capns1 attenuates myocardial infarction injury via restoring mitochondrial function and inhibiting inflammasome activation.
Xiao Z, Wei X, Li M, Yang K, Chen R, Su Y, Yu Z, Liang Y, Ge J
Journal of molecular and cellular cardiology 2023 Oct;183:54-66
Journal of molecular and cellular cardiology 2023 Oct;183:54-66
M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats.
Huang JG, Ren JX, Chen Y, Tian MF, Zhou L, Wen J, Song XS, Wu YL, Yang QH, Jiang PR, Wang JN, Yang Q
Neural regeneration research 2023 Oct;18(10):2208-2218
Neural regeneration research 2023 Oct;18(10):2208-2218
Nintedanib inhibits normal human vitreous-induced epithelial-mesenchymal transition in human retinal pigment epithelial cells.
Yin Y, Liu S, Liu H, Wu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115403
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115403
Molecular insights of a CBP/β-catenin-signaling inhibitor on nonalcoholic steatohepatitis-induced liver fibrosis and disorder.
Yamaji K, Iwabuchi S, Tokunaga Y, Hashimoto S, Yamane D, Toyama S, Kono R, Kitab B, Tsukiyama-Kohara K, Osawa Y, Hayashi Y, Hishima T, Tateno C, Kimura K, Okanoue T, Kohara M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115379
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Oct;166:115379
Farnesoid X receptor activation is required for the anti-inflammatory and anti-oxidative stress effects of Alisol B 23-acetate in carbon tetrachloride-induced liver fibrosis in mice.
Zhang L, Lin W, Cai Y, Huang Z, Zhao R, Yan T, Xu H, Liu Z
International immunopharmacology 2023 Oct;123:110768
International immunopharmacology 2023 Oct;123:110768
Hierarchically Released Liquid Metal Nanoparticles for Mild Photothermal Therapy/Chemotherapy of Breast Cancer Bone Metastases via Remodeling Tumor Stromal Microenvironment.
Shen Y, Zou Y, Bie B, Lv Y
Advanced healthcare materials 2023 Oct;12(27):e2301080
Advanced healthcare materials 2023 Oct;12(27):e2301080
Sox7-positive endothelial progenitors establish coronary arteries and govern ventricular compaction.
Chiang IK, Humphrey D, Mills RJ, Kaltzis P, Pachauri S, Graus M, Saha D, Wu Z, Young P, Sim CB, Davidson T, Hernandez-Garcia A, Shaw CA, Renwick A, Scott DA, Porrello ER, Wong ES, Hudson JE, Red-Horse K, Del Monte-Nieto G, Francois M
EMBO reports 2023 Oct 9;24(10):e55043
EMBO reports 2023 Oct 9;24(10):e55043
Theaflavine inhibits hepatic stellate cell activation by modulating the PKA/LKB1/AMPK/GSK3β cascade and subsequently enhancing Nrf2 signaling.
Shu G, Sun H, Zhang T, Zhu A, Lei X, Wang C, Song A, Deng X
European journal of pharmacology 2023 Oct 5;956:175964
European journal of pharmacology 2023 Oct 5;956:175964
Fu-Zheng-Tong-Luo formula promotes autophagy and alleviates idiopathic pulmonary fibrosis by controlling the Janus kinase 2/signal transducer and activator of transcription 3 pathway.
Zhang X, Su J, Lin J, Liu L, Wu J, Yuan W, Zhang Y, Chen Q, Su ZJ, Xu G, Sun M, Zhang Y, Chen X, Zhang W
Journal of ethnopharmacology 2023 Oct 5;314:116633
Journal of ethnopharmacology 2023 Oct 5;314:116633
NLRP3 Inflammasome Activates Endothelial-to-Mesenchymal Transition via Focal Adhesion Kinase Pathway in Bleomycin-Induced Pulmonary Fibrosis.
Chen WC, Yu WK, Su VY, Hsu HS, Yang KY
International journal of molecular sciences 2023 Oct 31;24(21)
International journal of molecular sciences 2023 Oct 31;24(21)
CRTC2 activates the epithelial-mesenchymal transition of diabetic kidney disease through the CREB-Smad2/3 pathway.
Li Y, Zhang Y, Shi H, Liu X, Li Z, Zhang J, Wang X, Wang W, Tong X
Molecular medicine (Cambridge, Mass.) 2023 Oct 26;29(1):146
Molecular medicine (Cambridge, Mass.) 2023 Oct 26;29(1):146
Sodium-glucose cotransporter 2 inhibitor canagliflozin alleviates vascular calcification through suppression of nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3 inflammasome.
Chen A, Lan Z, Li L, Xie L, Liu X, Yang X, Wang S, Liang Q, Dong Q, Feng L, Li Y, Ye Y, Fu M, Lu L, Yan J
Cardiovascular research 2023 Oct 24;119(13):2368-2381
Cardiovascular research 2023 Oct 24;119(13):2368-2381
Activation of acetyl-CoA synthetase 2 mediates kidney injury in diabetic nephropathy.
Lu J, Li XQ, Chen PP, Zhang JX, Liu L, Wang GH, Liu XQ, Jiang TT, Wang MY, Liu WT, Ruan XZ, Ma KL
JCI insight 2023 Oct 23;8(20)
JCI insight 2023 Oct 23;8(20)
The Dual-Mode Transition of Myofibroblasts Derived from Hepatic Stellate Cells in Liver Fibrosis.
Yan M, Xie Y, Yao J, Li X
International journal of molecular sciences 2023 Oct 23;24(20)
International journal of molecular sciences 2023 Oct 23;24(20)
Targeting ferroptosis attenuates podocytes injury and delays tubulointerstitial fibrosis in focal segmental glomerulosclerosis.
He X, Yang L, Wang M, Zhang P, Wang R, Ji D, Gao C, Xia Z
Biochemical and biophysical research communications 2023 Oct 20;678:11-16
Biochemical and biophysical research communications 2023 Oct 20;678:11-16
Single-cell transcriptome profiling reveals immune and stromal cell heterogeneity in primary Sjögren's syndrome.
Xiang N, Xu H, Zhou Z, Wang J, Cai P, Wang L, Tan Z, Zhou Y, Zhang T, Zhou J, Liu K, Luo S, Fang M, Wang G, Chen Z, Guo C, Li X
iScience 2023 Oct 20;26(10):107943
iScience 2023 Oct 20;26(10):107943
Minichromosome maintenance 6 protects against renal fibrogenesis by regulating DUSP6-mediated ERK/GSK-3β/Snail1 signaling.
Huang J, Xu ZF, Liu F, Song AN, Su H, Zhang C
iScience 2023 Oct 20;26(10):107940
iScience 2023 Oct 20;26(10):107940
WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation.
Song K, Sun H, Tu B, Zhou Y, Lin LC, Liu ZY, Li R, Yang JJ, Zhang Y, Zhao JY, Tao H
iScience 2023 Oct 20;26(10):107931
iScience 2023 Oct 20;26(10):107931
High glucose promotes benign prostatic hyperplasia by downregulating PDK4 expression.
Wei P, Lin D, Luo C, Zhang M, Deng B, Cui K, Chen Z
Scientific reports 2023 Oct 20;13(1):17910
Scientific reports 2023 Oct 20;13(1):17910
Vitamin D(3) analogue calcipotriol inhibits the profibrotic effects of transforming growth factor- β1 on pancreatic stellate cells.
Zheng M, Li H, Gao Y, Brigstock DR, Gao R
European journal of pharmacology 2023 Oct 15;957:176000
European journal of pharmacology 2023 Oct 15;957:176000
Colchicine protects against the development of experimental abdominal aortic aneurysm.
Zhao Y, Shen QR, Chen YX, Shi Y, Wu WB, Li Q, Li DJ, Shen FM, Fu H
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
Clinical science (London, England : 1979) 2023 Oct 11;137(19):1533-1545
20(R)-ginsenoside Rg3-loaded polyurethane/marine polysaccharide based nanofiber dressings improved burn wound healing potentials.
Guo X, Xiu F, Bera H, Abbasi YF, Chen Y, Si L, Liu P, Zhao C, Tang X, Feng Y, Cun D, Zhao X, Yang M
Carbohydrate polymers 2023 Oct 1;317:121085
Carbohydrate polymers 2023 Oct 1;317:121085
Structural analysis and attenuates hyperuricemic nephropathy of dextran from the Imperata cylindrica Beauv. var. major (Nees) C. E. Hubb.
Yu W, Xiong Y, Liu M, Zeng D, Zhao H, Liu J, Lu W
Carbohydrate polymers 2023 Oct 1;317:121064
Carbohydrate polymers 2023 Oct 1;317:121064
Mannan-binding lectin ameliorates renal fibrosis by suppressing macrophage-to-myofibroblast transition.
Xu L, Jiang H, Xie J, Xu Q, Zhou J, Lu X, Wang M, Dong L, Zuo D
Heliyon 2023 Nov;9(11):e21882
Heliyon 2023 Nov;9(11):e21882
Pacenta polypeptide injection alleviates the fibrosis and inflammation in cigarette smoke extracts-induced BEAS-2B cells by modulating MMP-9/TIMP-1 signaling.
Xu W, Li F, Zhu L, Cheng M, Cheng Y
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Journal of biochemical and molecular toxicology 2023 Nov;37(11):e23453
Single-cell analysis reveals immune cellular components in odontogenic keratocysts.
Man QW, Li RF, Liu JF, Zhao Y, Liu B
Oral diseases 2023 Nov;29(8):3420-3432
Oral diseases 2023 Nov;29(8):3420-3432
Macrophage-derived inflammation promotes pulmonary vascular remodeling in hypoxia-induced pulmonary arterial hypertension mice.
Liu H, Wang Y, Zhang Q, Liu C, Ma Y, Huang P, Ge R, Ma L
Immunology letters 2023 Nov;263:113-122
Immunology letters 2023 Nov;263:113-122
Unleashing the healing potential: Exploring next-generation regenerative protein nanoscaffolds for burn wound recovery.
Si L, Guo X, Bera H, Chen Y, Xiu F, Liu P, Zhao C, Abbasi YF, Tang X, Foderà V, Cun D, Yang M
Asian journal of pharmaceutical sciences 2023 Nov;18(6):100856
Asian journal of pharmaceutical sciences 2023 Nov;18(6):100856
Butyrate alleviates renal fibrosis in CKD by regulating NLRP3-mediated pyroptosis via the STING/NF-κB/p65 pathway.
Tian X, Zeng Y, Tu Q, Jiao Y, Yao S, Chen Y, Sun L, Xia Q, Luo Y, Yuan L, Jiang Q
International immunopharmacology 2023 Nov;124(Pt B):111010
International immunopharmacology 2023 Nov;124(Pt B):111010
3D Prestress Bioprinting of Directed Tissues.
Li Y, Wu J, He C, He H, Xie M, Yao K, He J, Duan Y, Zhaung L, Wang P, He Y
Advanced healthcare materials 2023 Nov;12(28):e2301487
Advanced healthcare materials 2023 Nov;12(28):e2301487
Silk Acid as an Implantable Biomaterial for Tissue Regeneration.
Sun Z, Huang R, Lyu H, Yu X, Wang W, Li J, Lu X, Guo C
Advanced healthcare materials 2023 Nov;12(28):e2301439
Advanced healthcare materials 2023 Nov;12(28):e2301439
Caveolin-1 is critical for hepatic iron storage capacity in the development of nonalcoholic fatty liver disease.
Deng GH, Wu CF, Li YJ, Shi H, Zhong WC, Hong MK, Li JJ, Zhao JM, Liu C, Qin MC, Zeng ZY, Zhang WM, Yung KKL, Lv ZP, Gao L
Military Medical Research 2023 Nov 8;10(1):53
Military Medical Research 2023 Nov 8;10(1):53
Schisandrin B Alleviates Renal Tubular Cell Epithelial-Mesenchymal Transition and Mitochondrial Dysfunction by Kielin/Chordin-like Protein Upregulation via Akt Pathway Inactivation and Adenosine 5'-Monophosphate (AMP)-Activated Protein Kinase Pathway Activation in Diabetic Kidney Disease.
Liu W, Li F, Guo D, Du C, Zhao S, Li J, Yan Z, Hao J
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
Molecules (Basel, Switzerland) 2023 Nov 29;28(23)
Extracellular vesicle-derived silk fibroin nanoparticles loaded with MFGE8 accelerate skin ulcer healing by targeting the vascular endothelial cells.
Luo L, Zhang H, Zhang S, Luo C, Kan X, Lv J, Zhao P, Tian Z, Li C
Journal of nanobiotechnology 2023 Nov 29;21(1):455
Journal of nanobiotechnology 2023 Nov 29;21(1):455
A bacteria-derived tetramerized protein ameliorates nonalcoholic steatohepatitis in mice via binding and relocating acetyl-coA carboxylase.
Lin Y, Yang M, Huang L, Yang F, Fan J, Qiang Y, Chang Y, Zhou W, Yan L, Xiong J, Ping J, Chen S, Men D, Li F
Cell reports 2023 Nov 28;42(11):113453
Cell reports 2023 Nov 28;42(11):113453
Netrin-1 feedforward mechanism promotes pancreatic cancer liver metastasis via hepatic stellate cell activation, retinoid, and ELF3 signaling.
Dudgeon C, Casabianca A, Harris C, Ogier C, Bellina M, Fiore S, Bernet A, Ducarouge B, Goldschneider D, Su X, Pitarresi J, Hezel A, De S, Narrow W, Soliman F, Shields C, Vendramini-Costa DB, Prela O, Wang L, Astsaturov I, Mehlen P, Carpizo DR
Cell reports 2023 Nov 28;42(11):113369
Cell reports 2023 Nov 28;42(11):113369
Precisely Regulating M2 Subtype Macrophages for Renal Fibrosis Resolution.
Luo L, Wang S, Hu Y, Wang L, Jiang X, Zhang J, Liu X, Guo X, Luo Z, Zhu C, Xie M, Li Y, You J, Yang F
ACS nano 2023 Nov 28;17(22):22508-22526
ACS nano 2023 Nov 28;17(22):22508-22526
Four-dimensional hydrogel dressing adaptable to the urethral microenvironment for scarless urethral reconstruction.
Hua Y, Wang K, Huo Y, Zhuang Y, Wang Y, Fang W, Sun Y, Zhou G, Fu Q, Cui W, Zhang K
Nature communications 2023 Nov 22;14(1):7632
Nature communications 2023 Nov 22;14(1):7632
RGS5 maintaining vascular homeostasis is altered by the tumor microenvironment.
Kong P, Wang X, Gao YK, Zhang DD, Huang XF, Song Y, Zhang WD, Guo RJ, Li H, Han M
Biology direct 2023 Nov 20;18(1):78
Biology direct 2023 Nov 20;18(1):78
FAM171B stabilizes vimentin and enhances CCL2-mediated TAM infiltration to promote bladder cancer progression.
Hu WM, Li M, Ning JZ, Tang YQ, Song TB, Li LZ, Zou F, Cheng F, Yu WM
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Journal of experimental & clinical cancer research : CR 2023 Nov 2;42(1):290
Exosomes derived from cardiac fibroblasts with angiotensin II stimulation provoke hypertrophy and autophagy inhibition in cardiomyocytes.
Xu ST, Zhang YX, Liu SL, Liu F, Ye JT
Biochemical and biophysical research communications 2023 Nov 19;682:199-206
Biochemical and biophysical research communications 2023 Nov 19;682:199-206
Agathis dammara Extract and its Monomer Araucarone Attenuate Abdominal Aortic Aneurysm in Mice.
Zhang Q, Cai Z, Yu Z, Di C, Qiu Y, Qi R
Cardiovascular drugs and therapy 2023 Nov 18;
Cardiovascular drugs and therapy 2023 Nov 18;
MircroRNA-92b as a negative regulator of the TGF-β signaling by targeting the type I receptor.
Yang S, Jiang K, Li L, Xiang J, Li Y, Kang L, Yang G, Liang Z
iScience 2023 Nov 17;26(11):108131
iScience 2023 Nov 17;26(11):108131
A role of TRIM59 in pulmonary hypertension: modulating the protein ubiquitylation modification.
Liu Y, Zhu L, Ming Y, Wu Z, Zhang L, Chen Q, Qi Y
Journal of translational medicine 2023 Nov 17;21(1):821
Journal of translational medicine 2023 Nov 17;21(1):821
Gracillin relieves pulmonary fibrosis by suppressing the STAT3 axis.
Xie M, Yang L, Cheng J, Qu H, Gu Y, Ding C, Xu X, Zhao C, Huang X, Wang L
Journal of ethnopharmacology 2023 Nov 15;316:116704
Journal of ethnopharmacology 2023 Nov 15;316:116704
Circ_16601 facilitates Hippo pathway signaling via the miR-5580-5p/FGB axis to promote my-CAF recruitment in the TME and LUAD progression.
Zhou J, Li P, Zhao X, Zhao Y, Luo J, Deng Y, Jiang N, Xiao Z, Zhang W, Zhou Y, Zhao J, Li P, Li Y, Tian Z
Respiratory research 2023 Nov 12;24(1):276
Respiratory research 2023 Nov 12;24(1):276
Electroacupuncture alleviates intrauterine adhesion through regulating autophagy in rats.
Liu J, Zhu Q, Pan Y, Hao S, Wang Z, Cui C, Li J, Huang Y, Xia L, Xu T, Cheng J, Shen J, Xia Y
Molecular human reproduction 2023 Nov 1;29(11)
Molecular human reproduction 2023 Nov 1;29(11)
cGAS-STING signaling pathway promotes hypoxia-induced renal fibrosis by regulating PFKFB3-mediated glycolysis.
Jiang A, Liu J, Wang Y, Zhang C
Free radical biology & medicine 2023 Nov 1;208:516-529
Free radical biology & medicine 2023 Nov 1;208:516-529
Folic acid supplementation rescues bladder injury in fetal rats with myelomeningocele.
Feng S, Yang Y, Yu Z, Bi Y
Birth defects research 2023 Nov 1;115(18):1685-1692
Birth defects research 2023 Nov 1;115(18):1685-1692
Klotho improves cardiac fibrosis, inflammatory cytokines, ferroptosis, and oxidative stress in mice with myocardial infarction.
Wang K, Li Z, Ding Y, Liu Z, Li Y, Liu X, Sun Y, Hong J, Zheng W, Qian L, Xu D
Journal of physiology and biochemistry 2023 May;79(2):341-353
Journal of physiology and biochemistry 2023 May;79(2):341-353
Dihydroartemisinin inhibits the activation and proliferation of hepatic stellate cells by regulating miR‑29b‑3p.
Huan S, Sun S, Song S, Dai J, Zhu G, Zhong Y, Ji Y, Zheng S, Yin G
International journal of molecular medicine 2023 May;51(5)
International journal of molecular medicine 2023 May;51(5)
Prolonged exposure to the herbicide atrazine promotes kidney fibrosis by activating Wnt/β-catenin signaling in rats.
Wang T, Huang X, Liu J, Liu W, Yang Z, He K, Chen J, Zhao L
Environmental toxicology 2023 May;38(5):1143-1152
Environmental toxicology 2023 May;38(5):1143-1152
Liver sinusoidal endothelial S1pr2 regulates experimental liver fibrosis through YAP/TGF-β signaling pathway.
Liao Y, Zhou C, Duan Y, Liu X, Yue J, Li X, Wu J, Wan C, Zhang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22905
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 May;37(5):e22905
CircRNA_0017076 acts as a sponge for miR-185-5p in the control of epithelial-to-mesenchymal transition of tubular epithelial cells during renal interstitial fibrosis.
Zhang F, Zou H, Li X, Liu J, Xie Y, Chen M, Yu J, Wu X, Guo B
Human cell 2023 May;36(3):1024-1040
Human cell 2023 May;36(3):1024-1040
Lycopene inhibits endothelial-to-mesenchymal transition of choroidal vascular endothelial cells in laser-induced mouse choroidal neovascularization.
Li L, Cao X, Huang L, Huang X, Gu J, Yu X, Zhu Y, Zhou Y, Song Y, Zhu M
Journal of cellular and molecular medicine 2023 May;27(10):1327-1340
Journal of cellular and molecular medicine 2023 May;27(10):1327-1340
Ambient particulate matter exposure plus chronic ethanol ingestion exacerbates hepatic fibrosis by triggering the mitochondrial ROS-ferroptosis signaling pathway in mice.
Ding S, Jiang J, Zhang G, Yu M, Zheng Y
Ecotoxicology and environmental safety 2023 May;256:114897
Ecotoxicology and environmental safety 2023 May;256:114897
A multifunctional neuromodulation platform utilizing Schwann cell-derived exosomes orchestrates bone microenvironment via immunomodulation, angiogenesis and osteogenesis.
Hao Z, Ren L, Zhang Z, Yang Z, Wu S, Liu G, Cheng B, Wu J, Xia J
Bioactive materials 2023 May;23:206-222
Bioactive materials 2023 May;23:206-222
Inhibitory effect of miR-138-5p on choroidal fibrosis in lens-induced myopia guinea pigs via suppressing the HIF-1α signaling pathway.
Li T, Li X, Hao Y, Liu J, Bao B, Yang Z, Zhou M, Wei H, Zhang R, Hao J, Jiang W, Bi H, Guo D
Biochemical pharmacology 2023 May;211:115517
Biochemical pharmacology 2023 May;211:115517
Nintedanib prevents TGF-β2-induced epithelial-mesenchymal transition in retinal pigment epithelial cells.
Yin Y, Liu S, Pu L, Luo J, Liu H, Wu W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114543
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 May;161:114543
Nr4a1 promotes renal interstitial fibrosis by regulating the p38 MAPK phosphorylation.
Tao Y, Tang C, Wei J, Shan Y, Fang X, Li Y
Molecular medicine (Cambridge, Mass.) 2023 May 9;29(1):63
Molecular medicine (Cambridge, Mass.) 2023 May 9;29(1):63
Cryptotanshinone induces apoptosis of activated hepatic stellate cells via modulating endoplasmic reticulum stress.
Hou XX, Li YW, Song JL, Zhang W, Liu R, Yuan H, Feng TT, Jiang ZY, Li WT, Zhu CL
World journal of gastroenterology 2023 May 7;29(17):2616-2627
World journal of gastroenterology 2023 May 7;29(17):2616-2627
EPAS1 prevents telomeric damage-induced senescence by enhancing transcription of TRF1, TRF2, and RAD50.
Li KQ, Liu GJ, Liu XY, Chen QF, Huang XY, Tu Q, Zhang J, Chang Q, Xie YH, Hua R, Xu DM, Liu Z, Zhao B
Zoological research 2023 May 18;44(3):636-649
Zoological research 2023 May 18;44(3):636-649
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure.
Li C, Zhang X, Li J, Liang L, Zeng J, Wen M, Pan L, Lv D, Liu M, Cheng Y, Huang H
European journal of pharmacology 2023 May 15;947:175676
European journal of pharmacology 2023 May 15;947:175676
Aristolocholic acid I promotes renal tubular epithelial fibrosis by upregulating matrix metalloproteinase-9 expression via activating the C3a/C3aR axis of macrophages.
Zhang Q, Ye J, Zhang Z, Hu Y, Wang X, Jiang W, Guo X, Chen L, Cheng S, Li J, Zhang L
Toxicology letters 2023 May 15;381:27-35
Toxicology letters 2023 May 15;381:27-35
Development and validation of a radiomics model of magnetic resonance for predicting liver metastasis in resectable pancreatic ductal adenocarcinoma patients.
Huang Y, Zhou S, Luo Y, Zou J, Li Y, Chen S, Gao M, Huang K, Lian G
Radiation oncology (London, England) 2023 May 10;18(1):79
Radiation oncology (London, England) 2023 May 10;18(1):79
The p53/miR-29a-3p axis mediates the antifibrotic effect of leonurine on angiotensin II-stimulated rat cardiac fibroblasts.
Xi T, Wang R, Pi D, Ouyang J, Yang J
Experimental cell research 2023 May 1;426(1):113556
Experimental cell research 2023 May 1;426(1):113556
Noncanonical atherosclerosis as the driving force in tricuspid aortic valve associated aneurysms - A trace collection.
Doppler C, Messner B, Mimler T, Schachner B, Rezk M, Ganhör C, Wechselberger C, Müller M, Puh S, Pröll J, Arbeithuber B, Müller T, Zierer A, Bernhard D
Journal of lipid research 2023 Mar;64(3):100338
Journal of lipid research 2023 Mar;64(3):100338
Deubiquitinating enzyme USP11 promotes renal tubular cell senescence and fibrosis via inhibiting the ubiquitin degradation of TGF-β receptor II.
Ni JY, Wang X, Xie HY, Yang NH, Li JY, Sun XA, Guo HJ, Zhou L, Zhang W, Liu J, Lu LM
Acta pharmacologica Sinica 2023 Mar;44(3):584-595
Acta pharmacologica Sinica 2023 Mar;44(3):584-595
ZD6474 Attenuates Fibrosis and Inhibits Neovascularization in Human Pterygium by Suppressing AKT-mTOR Signaling Pathway.
Liu W, Lin T, Gong L
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2023 Mar;39(2):128-138
Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 2023 Mar;39(2):128-138
m(6)A methylation-induced NR1D1 ablation disrupts the HSC circadian clock and promotes hepatic fibrosis.
Chen L, Xia S, Wang F, Zhou Y, Wang S, Yang T, Li Y, Xu M, Zhou Y, Kong D, Zhang Z, Shao J, Xu X, Zhang F, Zheng S
Pharmacological research 2023 Mar;189:106704
Pharmacological research 2023 Mar;189:106704
CCN2/CTGF promotes liver fibrosis through crosstalk with the Slit2/Robo signaling.
Pi L, Sun C, Jn-Simon N, Basha S, Thomas H, Figueroa V, Zarrinpar A, Cao Q, Petersen B
Journal of cell communication and signaling 2023 Mar;17(1):137-150
Journal of cell communication and signaling 2023 Mar;17(1):137-150
Deletion of LCMR1 in alveolar type II cells induces lethal impairment of lung structure and function in adult mice.
Wang Y, Li C, Wu Z, Dai Y, Liu L, Chen L
Journal of thoracic disease 2023 Mar 31;15(3):1445-1459
Journal of thoracic disease 2023 Mar 31;15(3):1445-1459
Curcumol suppresses endothelial-to-mesenchymal transition via inhibiting the AKT/GSK3β signaling pathway and alleviates pulmonary arterial hypertension in rats.
Nie X, Wu Z, Shang J, Zhu L, Liu Y, Qi Y
European journal of pharmacology 2023 Mar 15;943:175546
European journal of pharmacology 2023 Mar 15;943:175546
Benzylisoquinoline alkaloids inhibit lung fibroblast activation mainly via inhibiting TGF-β1/Smads and ERK1/2 pathway proteins.
Ren HL, Zhang JH, Xiao JH
Heliyon 2023 Jun;9(6):e16849
Heliyon 2023 Jun;9(6):e16849
FAM3A mediates the phenotypic switch of human aortic smooth muscle cells stimulated with oxidised low-density lipoprotein by influencing the PI3K-AKT pathway.
Yang L, Du B, Zhang S, Wang M
In vitro cellular & developmental biology. Animal 2023 Jun;59(6):431-442
In vitro cellular & developmental biology. Animal 2023 Jun;59(6):431-442
Collagen Triple Helix Repeat Containing 1 Deficiency Protects Against Airway Remodeling and Inflammation in Asthma Models In Vivo and In Vitro.
Feng Y, Hu J, Liu F, Shang Y
Inflammation 2023 Jun;46(3):925-940
Inflammation 2023 Jun;46(3):925-940
Efficacy of Danggui Buxue decoction on diabetic nephropathy-induced renal fibrosis in rats and possible mechanism.
Ye Z, Xian W, Ling GU, Zihang LI, Jingtian Z, Wenkai W, Liang Z, Mei X
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Jun;43(3):507-513
Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan 2023 Jun;43(3):507-513
A novel tetra-PEG based hydrogel for prevention of esophageal stricture after ESD in a porcine model.
Wei Y, Tang J, Li J, Hou X, Li L, Zhang D, Chai D, Zhao M, Liu F
Colloids and surfaces. B, Biointerfaces 2023 Jun;226:113321
Colloids and surfaces. B, Biointerfaces 2023 Jun;226:113321
Protective effects of methylprednisolone-cyclophosphamide treatment on bleomycin-induced pulmonary fibrosis.
Xu Q, Zhu W, Tang M, Zhang M, Liu Y, Li Z, Rao Z, He X, Ma R, Xue X
Cytokine 2023 Jun;166:156188
Cytokine 2023 Jun;166:156188
Oroxylin A activates ferritinophagy to induce hepatic stellate cell senescence against hepatic fibrosis by regulating cGAS-STING pathway.
Sun Y, Weng J, Chen X, Ma S, Zhang Y, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Jun;162:114653
Inflachromene inhibits intimal hyperplasia through the HMGB1/2- regulated TLR4-NF-κB pathway.
Teng S, Zhu Z, Wu C, He Y, Zhou S
International immunopharmacology 2023 Jun;119:110198
International immunopharmacology 2023 Jun;119:110198
Differences in p38-STAT3-S100A11 signaling after the administration of aristolochic acid I and IVa may account for the disparity in their nephrotoxicity.
Xian Z, Tian J, Zhao Y, Yi Y, Li C, Han J, Zhang Y, Wang Y, Wang L, Liu S, Pan C, Liu C, Wang D, Meng J, Tang X, Wang F, Liang A
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154815
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154815
Aloe-emodin ameliorated MI-induced cardiac remodeling in mice via inhibiting TGF-β/SMAD signaling via up-regulating SMAD7.
Yu J, Zhao X, Yan X, Li W, Liu Y, Wang J, Wang J, Yang Y, Hao Y, Liang Z, Tao Y, Yuan Y, Du Z
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154793
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jun;114:154793
Silencing of NOTCH3 Signaling in Meniscus Smooth Muscle Cells Inhibits Fibrosis and Exacerbates Degeneration in a HEYL-Dependent Manner.
Sun H, Liu F, Lin Z, Jiang Z, Wen X, Xu J, Zhang Z, Ma R
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(16):e2207020
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Jun;10(16):e2207020
Time-dependent effect of REV-ERBα agonist SR9009 on nonalcoholic steatohepatitis and gut microbiota in mice.
Ni Y, Nan S, Zheng L, Zhang L, Zhao Y, Fu Z
Chronobiology international 2023 Jun 3;40(6):769-782
Chronobiology international 2023 Jun 3;40(6):769-782
MgIG Attenuates Oxaliplatin-induced Hepatotoxicity through Suppression of Connexin 43 in Hepatic Stellate Cells.
Cao Y, Xia Y, Wang Y, Shi H, Wu Y, Lu Y
Journal of clinical and translational hepatology 2023 Jun 28;11(3):584-594
Journal of clinical and translational hepatology 2023 Jun 28;11(3):584-594
Dynamic interplay between IL-1 and WNT pathways in regulating dermal adipocyte lineage cells during skin development and wound regeneration.
Sun L, Zhang X, Wu S, Liu Y, Guerrero-Juarez CF, Liu W, Huang J, Yao Q, Yin M, Li J, Ramos R, Liao Y, Wu R, Xia T, Zhang X, Yang Y, Li F, Heng S, Zhang W, Yang M, Tzeng CM, Ji C, Plikus MV, Gallo RL, Zhang LJ
Cell reports 2023 Jun 27;42(6):112647
Cell reports 2023 Jun 27;42(6):112647
Identification of potential biomarkers for idiopathic pulmonary fibrosis and validation of TDO2 as a potential therapeutic target.
Wang R, Yang YM
World journal of cardiology 2023 Jun 26;15(6):293-308
World journal of cardiology 2023 Jun 26;15(6):293-308
Autophagy-Interfering Nanoboat Drifting along CD44-Golgi-ER Flow as RNAi Therapeutics for Hepatic Fibrosis.
Wang Y, Xiong L, Dong Z, Ran K, Bai W, Mo Z, Huang K, Ye Y, Tao Y, Yin S, Li M, He Q
ACS applied materials & interfaces 2023 Jun 21;15(24):28941-28953
ACS applied materials & interfaces 2023 Jun 21;15(24):28941-28953
Macrophage Dectin-1 mediates Ang II renal injury through neutrophil migration and TGF-β1 secretion.
Ye S, Huang H, Xiao Y, Han X, Shi F, Luo W, Chen J, Ye Y, Zhao X, Huang W, Wang Y, Lai D, Liang G, Fu G
Cellular and molecular life sciences : CMLS 2023 Jun 20;80(7):184
Cellular and molecular life sciences : CMLS 2023 Jun 20;80(7):184
HMGB1-induced activation of ER stress contributes to pulmonary artery hypertension in vitro and in vivo.
Zhang Q, Chen Y, Wang Q, Wang Y, Feng W, Chai L, Liu J, Li D, Chen H, Qiu Y, Shen N, Shi X, Xie X, Li M
Respiratory research 2023 Jun 2;24(1):149
Respiratory research 2023 Jun 2;24(1):149
Genetic lineage tracing reveals stellate cells as contributors to myofibroblasts in pancreas and islet fibrosis.
Wang J, Li T, Zhou Y, Wang X, Carvalho V, Ni C, Li W, Wang Q, Chen Y, Shang Z, Qiu S, Sun Z
iScience 2023 Jun 16;26(6):106988
iScience 2023 Jun 16;26(6):106988
Scarless wound healing programmed by core-shell microneedles.
Zhang Y, Wang S, Yang Y, Zhao S, You J, Wang J, Cai J, Wang H, Wang J, Zhang W, Yu J, Han C, Zhang Y, Gu Z
Nature communications 2023 Jun 10;14(1):3431
Nature communications 2023 Jun 10;14(1):3431
Ferroptosis in the Lacrimal Gland Is Involved in Dry Eye Syndrome Induced by Corneal Nerve Severing.
Liu X, Cui Z, Chen X, Li Y, Qiu J, Huang Y, Wang X, Chen S, Luo Q, Chen P, Zhuang J, Yu K
Investigative ophthalmology & visual science 2023 Jun 1;64(7):27
Investigative ophthalmology & visual science 2023 Jun 1;64(7):27
Venoarterial extracorporeal membrane oxygenation improves survival in a rat model of acute myocardial infarction.
Wei S, Cheng X, Li J, Zhai K, Huang J, Wang S, Li Y, Liu D
Artificial organs 2023 Jul;47(7):1163-1173
Artificial organs 2023 Jul;47(7):1163-1173
Ginseng saponin metabolite 20(S)-protopanaxadiol relieves pulmonary fibrosis by multiple-targets signaling pathways.
Ren G, Lv W, Ding Y, Wang L, Cui Z, Li R, Tian J, Zhang C
Journal of ginseng research 2023 Jul;47(4):543-551
Journal of ginseng research 2023 Jul;47(4):543-551
Total flavonoid extract from Dracocephalum moldavica L. improves pulmonary fibrosis by reducing inflammation and inhibiting the hedgehog signaling pathway.
He CH, Lv JM, Khan GJ, Duan H, Wang W, Zhai KF, Zou GA, Aisa HA
Phytotherapy research : PTR 2023 Jul;37(7):2745-2758
Phytotherapy research : PTR 2023 Jul;37(7):2745-2758
Dach1 deficiency drives alveolar epithelium apoptosis in pulmonary fibrosis via modulating C-Jun/Bim activity.
Lu Y, Tang K, Wang S, Tian Z, Fan Y, Li B, Wang M, Zhao J, Xie J
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Translational research : the journal of laboratory and clinical medicine 2023 Jul;257:54-65
Step-wise CAG@PLys@PDA-Cu(2+) modification on micropatterned nanofibers for programmed endothelial healing.
Yi B, Zhou B, Song Z, Yu L, Wang W, Liu W
Bioactive materials 2023 Jul;25:657-676
Bioactive materials 2023 Jul;25:657-676
Inhibiting Heat Shock Protein 90 Attenuates Nucleus Pulposus Fibrosis and Pathologic Angiogenesis Induced by Macrophages via Down-Regulating Cell Migration-Inducing Protein.
Zhang S, Wang P, Hu B, Lv X, Liu W, Chen S, Shao Z
The American journal of pathology 2023 Jul;193(7):960-976
The American journal of pathology 2023 Jul;193(7):960-976
Inhaled Lipid Nanoparticles Alleviate Established Pulmonary Fibrosis.
Li D, Zhao A, Zhu J, Wang C, Shen J, Zheng Z, Pan F, Liu Z, Chen Q, Yang Y
Small (Weinheim an der Bergstrasse, Germany) 2023 Jul;19(30):e2300545
Small (Weinheim an der Bergstrasse, Germany) 2023 Jul;19(30):e2300545
Fibroblast growth factor 10 delays the progression of osteoarthritis by attenuating synovial fibrosis via inhibition of IL-6/JAK2/STAT3 signaling in vivo and in vitro.
Su W, Zheng X, Zhou H, Yang S, Zhu X
Molecular immunology 2023 Jul;159:46-57
Molecular immunology 2023 Jul;159:46-57
Ginkgo biloba extract attenuates cisplatin-induced renal interstitial fibrosis by inhibiting the activation of renal fibroblasts through down-regulating the HIF-1α/STAT3/IL-6 pathway in renal tubular epithelial cells.
Zhang Y, Qin X, Yang Y, Li J, Li X, Zou X, Huang Z, Huang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul;115:154809
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul;115:154809
CAFs targeted ultrasound-responsive nanodroplets loaded V9302 and GLULsiRNA to inhibit melanoma growth via glutamine metabolic reprogramming and tumor microenvironment remodeling.
Ai C, Sun X, Xiao S, Guo L, Shang M, Shi D, Meng D, Zhao Y, Wang X, Li J
Journal of nanobiotechnology 2023 Jul 8;21(1):214
Journal of nanobiotechnology 2023 Jul 8;21(1):214
Anticoagulants Enhance Molecular and Cellular Immunotherapy of Cancer by Improving Tumor Microcirculation Structure and Function and Redistributing Tumor Infiltrates.
Wei F, Su Y, Quan Y, Li X, Zou Q, Zhang L, Li S, Jiang M, Lin G, Liang P, He J, Xie K
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Jul 5;29(13):2525-2539
Clinical cancer research : an official journal of the American Association for Cancer Research 2023 Jul 5;29(13):2525-2539
Metformin attenuates chronic lung allograft dysfunction: evidence in rat models.
Tian D, Zheng X, Tang H, Huang H, Wang J, Xu L, Li C, Yan H, Yu R, Nan J, Liu M, Guo X, Jian S, Wang T, Deng S, Pu Q, Liu L
Respiratory research 2023 Jul 29;24(1):192
Respiratory research 2023 Jul 29;24(1):192
Disruption of RCAN1.4 expression mediated by YY1/HDAC2 modulates chronic renal allograft interstitial fibrosis.
Zhang J, Zhang Y, Feng D, Zhou H, Gui Z, Zheng M, Hang Z, Gu M, Tan R
Cell death discovery 2023 Jul 28;9(1):271
Cell death discovery 2023 Jul 28;9(1):271
Identification of TGF-β-related genes in cardiac hypertrophy and heart failure based on single cell RNA sequencing.
Huang K, Wu H, Xu X, Wu L, Li Q, Han L
Aging 2023 Jul 26;15(14):7187-7218
Aging 2023 Jul 26;15(14):7187-7218
Achieving tissue-level softness on stretchable electronics through a generalizable soft interlayer design.
Li Y, Li N, Liu W, Prominski A, Kang S, Dai Y, Liu Y, Hu H, Wai S, Dai S, Cheng Z, Su Q, Cheng P, Wei C, Jin L, Hubbell JA, Tian B, Wang S
Nature communications 2023 Jul 26;14(1):4488
Nature communications 2023 Jul 26;14(1):4488
CXCL17 Attenuates Diesel Exhaust Emissions Exposure-Induced Lung Damage by Regulating Macrophage Function.
Yin Y, Mu C, Wang J, Wang Y, Hu W, Zhu W, Yu X, Hao W, Zheng Y, Li Q, Han W
Toxics 2023 Jul 26;11(8)
Toxics 2023 Jul 26;11(8)
Metformin suppressed tendon injury-induced adhesion via hydrogel-nanoparticle sustained-release system.
Jie Li Z, Bing Luo C, Liang Wang H, Sun J, Qian Yang Q, Lang Zhou Y
International journal of pharmaceutics 2023 Jul 25;642:123190
International journal of pharmaceutics 2023 Jul 25;642:123190
Wen-Shen-Jian-Pi-Hua-Tan decoction protects against early obesity-related glomerulopathy by improving renal bile acid composition and suppressing lipogenesis, inflammation, and fibrosis.
Song D, Zhang A, Hu X, Zeng M, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154861
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154861
Nanoengineered mesenchymal stem cell therapy for pulmonary fibrosis in young and aged mice.
Han MM, He XY, Tang L, Qi L, Yang MY, Wang Y, Xing L, Jeong JH, Jiang HL
Science advances 2023 Jul 21;9(29):eadg5358
Science advances 2023 Jul 21;9(29):eadg5358
Atractylenolide III Ameliorates Bile Duct Ligation-Induced Liver Fibrosis by Inhibiting the PI3K/AKT Pathway and Regulating Glutamine Metabolism.
Wang Y, Shi K, Tu J, Ke C, Chen N, Wang B, Liu Y, Zhou Z
Molecules (Basel, Switzerland) 2023 Jul 19;28(14)
Molecules (Basel, Switzerland) 2023 Jul 19;28(14)
Single-cell transcriptome sequencing-based analysis: probing the mechanisms of glycoprotein NMB regulation of epithelial cells involved in silicosis.
Yang S, Sun Y, Long M, Zhou X, Yuan M, Yang L, Luo W, Cheng Y, Zhang X, Jiang W, Chao J
Particle and fibre toxicology 2023 Jul 19;20(1):29
Particle and fibre toxicology 2023 Jul 19;20(1):29
Elevated retinal fibrosis in experimental myopia is involved in the activation of the PI3K/AKT/ERK signaling pathway.
Bao B, Liu J, Li T, Yang Z, Wang G, Xin J, Bi H, Guo D
Archives of biochemistry and biophysics 2023 Jul 15;743:109663
Archives of biochemistry and biophysics 2023 Jul 15;743:109663
Single-cell RNA sequencing reveals that HSD17B2 in cancer-associated fibroblasts promotes the development and progression of castration-resistant prostate cancer.
Zhang Y, Fan A, Li Y, Liu Z, Yu L, Guo J, Hou J, Li X, Chen W
Cancer letters 2023 Jul 10;566:216244
Cancer letters 2023 Jul 10;566:216244
Ginsenoside Rg3 liposomes regulate tumor microenvironment for the treatment of triple negative breast cancer.
Miao L, Ma H, Dong T, Zhao C, Gao T, Wu T, Xu H, Zhang J
Drug development and industrial pharmacy 2023 Jan;49(1):139-148
Drug development and industrial pharmacy 2023 Jan;49(1):139-148
Imbalance in ALR ubiquitination accelerates the progression of nonalcoholic steatohepatitis to hepatocellular carcinoma.
Zheng M, Ai Z, Guo Y, Chen Y, Xie P, An W
Oncogene 2023 Jan;42(4):308-321
Oncogene 2023 Jan;42(4):308-321
Quercetin inhibits the amphiregulin/EGFR signaling-mediated renal tubular epithelial-mesenchymal transition and renal fibrosis in obstructive nephropathy.
Wang Q, Wang F, Li X, Ma Z, Jiang D
Phytotherapy research : PTR 2023 Jan;37(1):111-123
Phytotherapy research : PTR 2023 Jan;37(1):111-123
Single-cell RNA sequencing analysis revealed cellular and molecular immune profiles in lung squamous cell carcinoma.
Hao B, Zhang Z, Lu Z, Xiong J, Fan T, Song C, He R, Zhang L, Pan S, Li D, Meng H, Lin W, Luo B, Yang J, Li N, Geng Q
Translational oncology 2023 Jan;27:101568
Translational oncology 2023 Jan;27:101568
Spinal Cord Stimulation Attenuates Neural Remodeling, Inflammation, and Fibrosis After Myocardial Infarction.
He Y, Sun Z, Jiang J, Yin X, Han J, Zhang Y, Zheng L
Neuromodulation : journal of the International Neuromodulation Society 2023 Jan;26(1):57-67
Neuromodulation : journal of the International Neuromodulation Society 2023 Jan;26(1):57-67
Qing Fei Hua Xian Decoction ameliorates bleomycin-induced pulmonary fibrosis by suppressing oxidative stress through balancing ACE-AngII-AT1R/ACE2-Ang-(1-7)-Mas axis.
Li RJ, Wu CY, Ke HL, Wang XP, Zhang YW
Iranian journal of basic medical sciences 2023 Jan;26(1):107-113
Iranian journal of basic medical sciences 2023 Jan;26(1):107-113
PD-L1 upregulation promotes drug-induced pulmonary fibrosis by inhibiting vimentin degradation.
Li Q, Deng MS, Wang RT, Luo H, Luo YY, Zhang DD, Chen KJ, Cao XF, Yang GM, Zhao TM, Xu B, Xu CX, Wang JM
Pharmacological research 2023 Jan;187:106636
Pharmacological research 2023 Jan;187:106636
Oroxylin A regulates cGAS DNA hypermethylation induced by methionine metabolism to promote HSC senescence.
Zhao D, Gao Y, Su Y, Zhou Y, Yang T, Li Y, Wang Y, Sun Y, Chen L, Zhang F, Zhang Z, Wang F, Shao J, Zheng S
Pharmacological research 2023 Jan;187:106590
Pharmacological research 2023 Jan;187:106590
The effects of taraxasterol on liver fibrosis revealed by RNA sequencing.
He H, Xu B, Ge P, Gao Y, Wei M, Li T, Zhang R, Li B, Cao H, Zhang K
International immunopharmacology 2023 Jan;114:109481
International immunopharmacology 2023 Jan;114:109481
Effective-compounds of Jinshui Huanxian formula ameliorates fibroblast activation in pulmonary fibrosis by inhibiting the activation of mTOR signaling.
Li J, Li K, Tian Y, Zhao P, Liu X, Li M, Bai Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154604
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;109:154604
Yishen-Qingli-Huoxue formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling.
Chen C, Sun S, Zhao J, Wu Q, He W, Sun W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154546
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154546
Elevated Angiotensin-II Levels Contribute to the Pathogenesis of Open-Angle Glaucoma Via Inducing the Expression of Fibrosis-Related Genes in Trabecular Meshwork Cells Through a ROS/NOX4/SMAD3 Axis.
Li H, Cui H, Ren J, Wang D, Zhao R, Zhu S, Liu S, Liu X, Tian S, Zhang Y, Zhao P, Li P, Thorne RF, Duan S
Cell transplantation 2023 Jan-Dec;32:9636897231162526
Cell transplantation 2023 Jan-Dec;32:9636897231162526
N-acetylglucosamine-bearing polymers mimicking O-GlcNAc-modified proteins elicit anti-fibrotic activities in myofibroblasts and activated stellate cells.
Ise H, Araki Y, Song I, Akatsuka G
Glycobiology 2023 Jan 8;33(1):17-37
Glycobiology 2023 Jan 8;33(1):17-37
Neuron-Glial Antigen 2 Participates in Liver Fibrosis via Regulating the Differentiation of Bone Marrow Mesenchymal Stem Cell to Myofibroblast.
Yang L, Zhang H, Dong C, Yue W, Xue R, Liu F, Yang L, Li L
International journal of molecular sciences 2023 Jan 7;24(2)
International journal of molecular sciences 2023 Jan 7;24(2)
Cryptotanshinone modulates proliferation, apoptosis, and fibrosis through inhibiting AR and EGFR/STAT3 axis to ameliorate benign prostatic hyperplasia progression.
Wei P, Lin D, Zhang M, Luo C, Wu X, Deng B, Cui K, Chen Z
European journal of pharmacology 2023 Jan 5;938:175434
European journal of pharmacology 2023 Jan 5;938:175434
Baicalin prevents fibrosis of human trabecular meshwork cells via inhibiting the MyD88/NF-κB pathway.
Li L, Liu Q, Shi L, Zhou X, Wu W, Wang X, Wang L, Wu Z
European journal of pharmacology 2023 Jan 5;938:175425
European journal of pharmacology 2023 Jan 5;938:175425
Facile preparation of a novel nanoemulsion based hyaluronic acid hydrogel loading with Poria cocos triterpenoids extract for wound dressing.
Ding X, Li S, Tian M, Yang P, Ding Y, Wang Y, Duan G, Zhang D, Chen B, Tan Q
International journal of biological macromolecules 2023 Jan 31;226:1490-1499
International journal of biological macromolecules 2023 Jan 31;226:1490-1499
Increased β1-adrenergic receptor antibody confers a vulnerable substrate for atrial fibrillation via mediating Ca2+ mishandling and atrial fibrosis in active immunization rabbit models.
Sun H, Song J, Li K, Li Y, Shang L, Zhou Q, Lu Y, Zong Y, He X, Kari M, Yang H, Zhou X, Zhang L, Tang B
Clinical science (London, England : 1979) 2023 Jan 31;137(2):195-217
Clinical science (London, England : 1979) 2023 Jan 31;137(2):195-217
Biejiajian pill inhibits progression of hepatocellular carcinoma by downregulating PDGFRβ signaling in cancer-associated fibroblasts.
Chen W, Yang X, Sun J, Chen Y, Zhao W, He C, An H, Pang J, Xu W, Wen B, Sun H, He S
Journal of ethnopharmacology 2023 Jan 30;301:115825
Journal of ethnopharmacology 2023 Jan 30;301:115825
Exosomes derived from human adipose mesenchymal stem cells ameliorate hepatic fibrosis by inhibiting PI3K/Akt/mTOR pathway and remodeling choline metabolism.
Zhang Z, Shang J, Yang Q, Dai Z, Liang Y, Lai C, Feng T, Zhong D, Zou H, Sun L, Su Y, Yan S, Chen J, Yao Y, Shi Y, Huang X
Journal of nanobiotechnology 2023 Jan 25;21(1):29
Journal of nanobiotechnology 2023 Jan 25;21(1):29
PKR deficiency delays vascular aging via inhibiting GSDMD-mediated endothelial cell hyperactivation.
Peng Z, Tan X, Xie L, Li Z, Zhou S, Li Y
iScience 2023 Jan 20;26(1):105909
iScience 2023 Jan 20;26(1):105909
Orally administration of cerium oxide nanozyme for computed tomography imaging and anti-inflammatory/anti-fibrotic therapy of inflammatory bowel disease.
Cao Y, Cheng K, Yang M, Deng Z, Ma Y, Yan X, Zhang Y, Jia Z, Wang J, Tu K, Liang J, Zhang M
Journal of nanobiotechnology 2023 Jan 19;21(1):21
Journal of nanobiotechnology 2023 Jan 19;21(1):21
HDAC7/c-Myc signaling pathway promotes the proliferation and metastasis of choroidal melanoma cells.
Zhang Y, Ding P, Wang Y, Shao C, Guo K, Yang H, Feng Y, Ning J, Pan M, Wang P, Yan X, Ma Z, Han J
Cell death & disease 2023 Jan 18;14(1):38
Cell death & disease 2023 Jan 18;14(1):38
Endosulfan induced kidney cell injury by modulating ACE2 through up-regulating miR-429 in HK-2 cells.
Zhang B, Liu S, Sun Y, Xu D
Toxicology 2023 Jan 15;484:153392
Toxicology 2023 Jan 15;484:153392
20-Hydroxytetraenoic acid induces hepatic fibrosis via the TGF-β1/Smad3 signaling pathway.
Li B, Ma Y, Tan L, Ren H, Wu L, Su Q, Song J, Chen W, Gong P, Jin Y
Toxicology letters 2023 Jan 15;373:1-12
Toxicology letters 2023 Jan 15;373:1-12
The m6A demethylase FTO promotes keloid formation by up-regulating COL1A1.
Ren S, Ji Y, Wang M, Ye M, Huang L, Cai X
Annals of translational medicine 2023 Jan 15;11(1):15
Annals of translational medicine 2023 Jan 15;11(1):15
Cell-Permeable PROTAC Degraders against KEAP1 Efficiently Suppress Hepatic Stellate Cell Activation through the Antioxidant and Anti-Inflammatory Pathway.
Wang F, Zhan Y, Li M, Wang L, Zheng A, Liu C, Wang H, Wang T
ACS pharmacology & translational science 2023 Jan 13;6(1):76-87
ACS pharmacology & translational science 2023 Jan 13;6(1):76-87
Endoscopy Deliverable and Mushroom-Cap-Inspired Hyperboloid-Shaped Drug-Laden Bioadhesive Hydrogel for Stomach Perforation Repair.
Liu S, Luan Z, Wang T, Xu K, Luo Q, Ye S, Wang W, Dan R, Shu Z, Huang Y, Mequanint K, Fan C, Xing M, Yang S
ACS nano 2023 Jan 10;17(1):111-126
ACS nano 2023 Jan 10;17(1):111-126
Macrophage-derived exosomal lncRNA MSTRG.91634.7 inhibits fibroblasts activation by targeting PINK1 in silica-induced lung fibrosis.
Ban J, Liu F, Zhang Q, Chang S, Zeng X, Chen J
Toxicology letters 2023 Jan 1;372:36-44
Toxicology letters 2023 Jan 1;372:36-44
VX-765 attenuates silica-induced lung inflammatory injury and fibrosis by modulating alveolar macrophages pyroptosis in mice.
Tao H, Zhao H, Mo A, Shao L, Ge D, Liu J, Hu W, Xu K, Ma Q, Wang W, Wang W, Cao H, Mu M, Tao X, Wang J
Ecotoxicology and environmental safety 2023 Jan 1;249:114359
Ecotoxicology and environmental safety 2023 Jan 1;249:114359
Type 1 diabetes mellitus leads to gingivitis and an early compensatory increase in bone remodeling.
Yuan X, Amin V, Zhu T, Kittaka M, Ueki Y, Bellido TM, Turkkahraman H
Journal of periodontology 2023 Feb;94(2):277-289
Journal of periodontology 2023 Feb;94(2):277-289
Generation of an induced pluripotent stem cell line (IPCASi001-A) from an autism spectrum disorder individual without intellectual disability.
Yang L, Lu S, Yang Z, Yao J, Zhou P, Zhao M
Stem cell research 2023 Feb;66:102994
Stem cell research 2023 Feb;66:102994
Deposition of platelet-derived microparticles in podocytes contributes to diabetic nephropathy.
Huang SJ, Zhang Y, Wang GH, Lu J, Chen PP, Zhang JX, Li XQ, Yuan BY, Liu XQ, Jiang TT, Wang MY, Liu WT, Ruan XZ, Liu BC, Ma KL
International urology and nephrology 2023 Feb;55(2):355-366
International urology and nephrology 2023 Feb;55(2):355-366
Glycyrrhizic acid improves tacrolimus-induced renal injury by regulating autophagy.
Cao R, Li Y, Hu X, Qiu Y, Li S, Xie Y, Xu C, Lu C, Chen G, Yang J
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22749
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Feb;37(2):e22749
In Situ Endothelialization of Free-Form 3D Network of Interconnected Tubular Channels via Interfacial Coacervation by Aqueous-in-Aqueous Embedded Bioprinting.
Zhang S, Qi C, Zhang W, Zhou H, Wu N, Yang M, Meng S, Liu Z, Kong T
Advanced materials (Deerfield Beach, Fla.) 2023 Feb;35(7):e2209263
Advanced materials (Deerfield Beach, Fla.) 2023 Feb;35(7):e2209263
miRNA‑92a inhibits vascular smooth muscle cell phenotypic modulation and may help prevent in‑stent restenosis.
Jiang F, Zhang B, Zhang X, Zhang R, Lu Q, Shi F, Xu J, Deng L
Molecular medicine reports 2023 Feb;27(2)
Molecular medicine reports 2023 Feb;27(2)
Effects of substrate topography on the regulation of human fibroblasts and capsule formation via modulating macrophage polarization.
Chen C, Chen Y, Lan YJ, Tian MN, Zhang YM, Lei ZY, Fan DL
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113086
Colloids and surfaces. B, Biointerfaces 2023 Feb;222:113086
Fc Fragment of IgE Receptor Ig (FCER1G) acts as a key gene involved in cancer immune infiltration and tumour microenvironment.
Yang R, Chen Z, Liang L, Ao S, Zhang J, Chang Z, Wang Z, Zhou Y, Duan X, Deng T
Immunology 2023 Feb;168(2):302-319
Immunology 2023 Feb;168(2):302-319
A small-molecule JNK inhibitor JM-2 attenuates high-fat diet-induced non-alcoholic fatty liver disease in mice.
Jin L, Wang M, Yang B, Ye L, Zhu W, Zhang Q, Lou S, Zhang Y, Luo W, Liang G
International immunopharmacology 2023 Feb;115:109587
International immunopharmacology 2023 Feb;115:109587
Hepatic stellate cell-released CXCL1 aggravates HCC malignant behaviors through the MIR4435-2HG/miR-506-3p/TGFB1 axis.
Li S, Hu X, Yu S, Yi P, Chen R, Huang Z, Huang Y, Huang Y, Zhou R, Fan X
Cancer science 2023 Feb;114(2):504-520
Cancer science 2023 Feb;114(2):504-520
LIM and Cysteine-Rich Domains 1 Promotes Transforming Growth Factor β1-Induced Epithelial-Mesenchymal Transition in Human Kidney 2 Cells.
Yu R, Wu Y, He P, Bai Y, Zhang Y, Bian X, Sun G, Zhang B
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100016
Laboratory investigation; a journal of technical methods and pathology 2023 Feb;103(2):100016
Prognostic Value of CXCL12 in Non-Small Cell Lung Cancer Patients Undergoing Tumor Resection.
Kogue Y, Kobayashi H, Nakamura Y, Takano T, Furuta C, Kawano O, Yasuma T, Nishimura T, D'Alessandro-Gabazza CN, Fujimoto H, Gabazza EC, Kobayashi T, Fukai I
Pharmaceuticals (Basel, Switzerland) 2023 Feb 7;16(2)
Pharmaceuticals (Basel, Switzerland) 2023 Feb 7;16(2)
Secretome of hESC-Derived MSC-like Immune and Matrix Regulatory Cells Mitigate Pulmonary Fibrosis through Antioxidant and Anti-Inflammatory Effects.
Hu W, Yang J, Xue J, Ma J, Wu S, Wang J, Xu R, Wei J, Wang Y, Wang S, Liu X
Biomedicines 2023 Feb 5;11(2)
Biomedicines 2023 Feb 5;11(2)
BMAL1/p53 mediating bronchial epithelial cell autophagy contributes to PM2.5-aggravated asthma.
Chen SJ, Huang Y, Yu F, Feng X, Zheng YY, Li Q, Niu Q, Jiang YH, Zhao LQ, Wang M, Cheng PP, Song LJ, Liang LM, He XL, Xiong L, Xiang F, Wang X, Ma WL, Ye H
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Cell communication and signaling : CCS 2023 Feb 20;21(1):39
Macrophage-derived GPNMB trapped by fibrotic extracellular matrix promotes pulmonary fibrosis.
Wang J, Zhang X, Long M, Yuan M, Yin J, Luo W, Wang S, Cai Y, Jiang W, Chao J
Communications biology 2023 Feb 2;6(1):136
Communications biology 2023 Feb 2;6(1):136
Aerobic exercise inhibits renal EMT by promoting irisin expression in SHR.
Luo M, Luo S, Xue Y, Chang Q, Yang H, Dong W, Zhang T, Cao S
iScience 2023 Feb 17;26(2):105990
iScience 2023 Feb 17;26(2):105990
Nanodrug rescues liver fibrosis via synergistic therapy with H(2)O(2) depletion and Saikosaponin b1 sustained release.
Dong H, Han X, Hao M, Yang Q, Lyu Q, Tang D, Shen Z, Wang K, Kuang H, Cao G, Peng M, Shao M
Communications biology 2023 Feb 16;6(1):184
Communications biology 2023 Feb 16;6(1):184
Intermedin 1-53 Ameliorates Atrial Fibrosis and Reduces Inducibility of Atrial Fibrillation via TGF-β1/pSmad3 and Nox4 Pathway in a Rat Model of Heart Failure.
Ma S, Yan F, Hou Y
Journal of clinical medicine 2023 Feb 15;12(4)
Journal of clinical medicine 2023 Feb 15;12(4)
Gut microbiota and bile acids partially mediate the improvement of fibroblast growth factor 21 on methionine-choline-deficient diet-induced non-alcoholic fatty liver disease mice.
Lin D, Sun Q, Liu Z, Pan J, Zhu J, Wang S, Jia S, Zheng M, Li X, Gong F
Free radical biology & medicine 2023 Feb 1;195:199-218
Free radical biology & medicine 2023 Feb 1;195:199-218
Estrogen inhibits the differentiation of fibroblasts induced by high stiffness matrix by enhancing DNMT1 expression.
Zhao Z, Huang G, He Y, Zuo X, Han W, Li H
Tissue & cell 2023 Dec;85:102207
Tissue & cell 2023 Dec;85:102207
RGS1 mediates renal interstitial fibrosis through activation of the inflammatory response.
Lu T, Chen S, Xu J
Archives of biochemistry and biophysics 2023 Dec;750:109744
Archives of biochemistry and biophysics 2023 Dec;750:109744
STAT6 promoting oxalate crystal deposition-induced renal fibrosis by mediating macrophage-to-myofibroblast transition via inhibiting fatty acid oxidation.
Yuan T, Xia Y, Pan S, Li B, Ye Z, Yan X, Hu W, Li L, Song B, Yu W, Li H, Rao T, Lin F, Zhou X, Cheng F
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Dec;72(12):2111-2126
Inflammation research : official journal of the European Histamine Research Society ... [et al.] 2023 Dec;72(12):2111-2126
Evaluation of topical methylene blue nanoemulsion for wound healing in diabetic mice.
Gao Y, Jiang Z, Xu B, Mo R, Li S, Jiang Y, Zhao D, Cao W, Chen B, Tian M, Tan Q
Pharmaceutical biology 2023 Dec;61(1):1462-1473
Pharmaceutical biology 2023 Dec;61(1):1462-1473
Loke zupa decoction attenuates bronchial EMT-mediated airway remodelling in chronic asthma through the PI3K-Akt/HIF-1α signaling pathway.
Liu J, Li L, Han X, Chen Y, Diao J
Pharmaceutical biology 2023 Dec;61(1):1332-1342
Pharmaceutical biology 2023 Dec;61(1):1332-1342
Integrating network pharmacology and experimental validation to decipher the mechanism of the Chinese herbal prescription modified Shen-Yan-Fang-Shuai formula in treating diabetic nephropathy.
Yu B, Zhou M, Dong Z, Zheng H, Zhao Y, Zhou J, Zhang C, Wei F, Yu G, Liu WJ, Liu H, Wang Y
Pharmaceutical biology 2023 Dec;61(1):1222-1233
Pharmaceutical biology 2023 Dec;61(1):1222-1233
Increased m6A-RNA methylation and demethylase FTO suppression is associated with silica-induced pulmonary inflammation and fibrosis.
Xu Y, Wang L, Qian R, Zhao M, Chen X, Sun D, Wang Y, Cheng W, Chen Y, He Q, Dai Y, Yao Y
Toxicology 2023 Dec;500:153673
Toxicology 2023 Dec;500:153673
KPNA2 Silencing, Regulated by E3 Ubiquitin Ligase FBXW7, Alleviates Endothelial Dysfunction and Inflammation Through Inhibiting the Nuclear Translocation of p65 and IRF3: A Possible Therapeutic Approach for Atherosclerosis.
Xing Z, Zhen Y, Chen J, Du M, Li D, Liu R, Zheng J
Inflammation 2023 Dec;46(6):2071-2088
Inflammation 2023 Dec;46(6):2071-2088
Human umbilical cord mesenchymal stem cell exosomes alleviate acute kidney injury by inhibiting pyroptosis in rats and NRK-52E cells.
Wan Y, Yu Y, Yu C, Luo J, Wen S, Shen L, Wei G, Hua Y
Renal failure 2023 Dec;45(1):2221138
Renal failure 2023 Dec;45(1):2221138
Exoskeleton Partial-Coated Stem Cells for Infarcted Myocardium Restoring.
He H, Yuan Y, Wu Y, Lu J, Yang X, Lu K, Liu A, Cao Z, Sun M, Yu M, Wang H
Advanced materials (Deerfield Beach, Fla.) 2023 Dec;35(52):e2307169
Advanced materials (Deerfield Beach, Fla.) 2023 Dec;35(52):e2307169
Vitamin D3 alleviates lung fibrosis of type 2 diabetic rats via SIRT3 mediated suppression of pyroptosis.
Tang L, Zhang D, Zhang Y, Peng Y, Li M, Song H, Chen H, Li W, Li X
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1618-1627
Apoptosis : an international journal on programmed cell death 2023 Dec;28(11-12):1618-1627
Polydatin alleviates bleomycin-induced pulmonary fibrosis and alters the gut microbiota in a mouse model.
Yang J, Shi X, Gao R, Fan L, Chen R, Cao Y, Xu T, Yang J
Journal of cellular and molecular medicine 2023 Dec;27(23):3717-3728
Journal of cellular and molecular medicine 2023 Dec;27(23):3717-3728
Engineered muscle from micro-channeled PEG scaffold with magnetic Fe(3)O(4) fixation towards accelerating esophageal muscle repair.
Luo Y, Chen Y, Gu Z, Ni R, Feng P, Hu Z, Song L, Shen X, Gu C, Li J, Du T, Yang L, Zhang H, Zhu Y
Materials today. Bio 2023 Dec;23:100853
Materials today. Bio 2023 Dec;23:100853
Polyethylene glycol crosslinked decellularized single liver lobe scaffolds with vascular endothelial growth factor promotes angiogenesis in vivo.
Zhang JS, Wang ZB, Lai ZZ, Yang JW, Song WJ, Wei YB, Mei J, Wang JG
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Dec;22(6):622-631
Hepatobiliary & pancreatic diseases international : HBPD INT 2023 Dec;22(6):622-631
Overexpression of LOX-1 in hepatocytes protects vascular smooth muscle cells from phenotype transformation and wire injury induced carotid neoatherosclerosis through ALOX15.
Zhang Q, Du G, Tong L, Guo X, Wei Y
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166805
Triptolide attenuates CCL(4)-induced liver fibrosis by regulating the differentiation of CD(4)(+) T cells in mice.
Jiang S, Feng J, Jiang Y, Lu Z, Kong J, Li X, Lian H, Zhang F, Li Y, Li J
International immunopharmacology 2023 Dec;125(Pt B):111206
International immunopharmacology 2023 Dec;125(Pt B):111206
BMAL1 inhibits renal fibrosis and renal interstitial inflammation by targeting the ERK1/2/ELK-1/Egr-1 axis.
Chen W, Zhao S, Xing J, Yu W, Rao T, Zhou X, Ruan Y, Li S, Xia Y, Song T, Zou F, Li W, Cheng F
International immunopharmacology 2023 Dec;125(Pt B):111140
International immunopharmacology 2023 Dec;125(Pt B):111140
Sodium alginate combined with oxymatrine ameliorates CCl(4)-induced chemical hepatic fibrosis in mice.
He C, Wang W, Wei G, Wang Y, Wei Y, Wang J, Zhang Z
International immunopharmacology 2023 Dec;125(Pt A):111144
International immunopharmacology 2023 Dec;125(Pt A):111144
Tamoxifen induced cardiac damage via the IL-6/p-STAT3/PGC-1α pathway.
Meng T, Zhang D, Zhang Y, Tian P, Chen J, Liu A, Li Y, Song C, Zheng Y, Su G
International immunopharmacology 2023 Dec;125(Pt A):110978
International immunopharmacology 2023 Dec;125(Pt A):110978
Isovitexin alleviates hepatic fibrosis by regulating miR-21-mediated PI3K/Akt signaling and glutathione metabolic pathway: based on transcriptomics and metabolomics.
Huang Y, Luo W, Chen S, Su H, Zhu W, Wei Y, Qiu Y, Long Y, Shi Y, Wei J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Dec;121:155117
Oleanolic acid derivative alleviates cardiac fibrosis through inhibiting PTP1B activity and regulating AMPK/TGF-β/Smads pathway.
Wang AH, Ma HY, Yi YL, Zhu SJ, Yu ZW, Zhu J, Mei S, Bahetibike S, Lu YQ, Huang LT, Yang RY, Rui-Wang, Xiao SL, Qi R
European journal of pharmacology 2023 Dec 5;960:176116
European journal of pharmacology 2023 Dec 5;960:176116
Suppressive effect of nitric oxide synthase (NOS) inhibitor L-NMMA acetate on choroidal fibrosis in experimental myopic guinea pigs through the nitric oxide signaling pathway.
Li T, Bao B, Hao Y, Liu J, Bi H, Guo D
European journal of pharmacology 2023 Dec 5;960:176111
European journal of pharmacology 2023 Dec 5;960:176111
The Long non-coding RNA MALAT1 functions as a competing endogenous RNA to regulate vascular remodeling by sponging miR-145-5p/HK2 in hypertension.
Yang J, Jiang G, Huang L, Liu Z, Jiang R, Cao G, Cao J, Zhu H, Chen L, Chen X, Pei F
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2284658
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2284658
Canagliflozin ameliorates hypobaric hypoxia-induced pulmonary arterial hypertension by inhibiting pulmonary arterial smooth muscle cell proliferation.
Tang L, Cai Q, Wang X, Li X, Li X, Chen L, Yang Y
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2278205
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2278205
CDN1163 alleviates SERCA2 dysfunction-induced pulmonary vascular remodeling by inhibiting the phenotypic transition of pulmonary artery smooth muscle cells.
Yu W, Zhang Q, Qiu Y, Chen H, Huang X, Xiao L, Xu G, Li S, Hu P, Tong X
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Clinical and experimental hypertension (New York, N.Y. : 1993) 2023 Dec 31;45(1):2272062
Muscone inhibits angiotensin II-induced cardiac hypertrophy through the STAT3, MAPK and TGF-β/SMAD signaling pathways.
Liu YJ, Xu JJ, Yang C, Li YL, Chen MW, Liu SX, Zheng XH, Luo P, Li R, Xiao D, Shan ZG
Molecular biology reports 2023 Dec 29;51(1):39
Molecular biology reports 2023 Dec 29;51(1):39
Exosomal ITGB6 from dormant lung adenocarcinoma cells activates cancer-associated fibroblasts by KLF10 positive feedback loop and the TGF-β pathway.
Feng X, Liu X, Xiang J, Xu J, Yin N, Wang L, Liu C, Liu Y, Zhao T, Zhao Z, Gao Y
Translational lung cancer research 2023 Dec 26;12(12):2520-2537
Translational lung cancer research 2023 Dec 26;12(12):2520-2537
Biodegradable nano black phosphorus based SDF1-α delivery system ameliorates Erectile Dysfunction in a cavernous nerve injury rat model by recruiting endogenous stem/progenitor cells.
Fu Q, Song L, Li J, Yi B, Huang Y, Zhang Z, Xin Z, Zhu J
Journal of nanobiotechnology 2023 Dec 18;21(1):487
Journal of nanobiotechnology 2023 Dec 18;21(1):487
A multi-functional double cross-linked chitosan hydrogel with tunable mechanical and antibacterial properties for skin wound dressing.
Liu F, Wang L, Zhai X, Ji S, Ye J, Zhu Z, Teng C, Dong W, Wei W
Carbohydrate polymers 2023 Dec 15;322:121344
Carbohydrate polymers 2023 Dec 15;322:121344
Anti-VEGFR2 F(ab')(2) drug conjugate promotes renal accumulation and glomerular repair in diabetic nephropathy.
Liu D, Song Y, Chen H, You Y, Zhu L, Zhang J, Xu X, Hu J, Huang X, Wu X, Xu X, Jiang S, Du Y
Nature communications 2023 Dec 13;14(1):8268
Nature communications 2023 Dec 13;14(1):8268
Hepatic Stellate Cell- and Liver Microbiome-Specific Delivery System for Dihydrotanshinone I to Ameliorate Liver Fibrosis.
Niu X, Meng Y, Cui J, Li R, Ding X, Niu B, Chang G, Xu N, Li G, Wang Y, Wang L
ACS nano 2023 Dec 12;17(23):23608-23625
ACS nano 2023 Dec 12;17(23):23608-23625
The application of a novel platform of multiparametric magnetic resonance imaging in a bioenvironmental toxic carbon tetrachloride-induced mouse model of liver fibrosis.
Qiuling L, Qilin Y, Cheng Y, Minping Z, Kangning W, Enhua X
Environmental research 2023 Dec 1;238(Pt 1):117130
Environmental research 2023 Dec 1;238(Pt 1):117130
Cell and rat serum, urine and tissue metabolomics analysis elucidates the key pathway changes associated with chronic nephropathy and reveals the mechanism of action of rhein.
Wang L, Yu X, Li H, He D, Zeng S, Xiang Z
Chinese medicine 2023 Dec 1;18(1):158
Chinese medicine 2023 Dec 1;18(1):158
Ginsenoside Rg1 Alleviates Lipopolysaccharide-Induced Fibrosis of Endometrial Epithelial Cells in Dairy Cows by Inhibiting Reactive Oxygen Species-Activated NLRP3.
Song L, Wang L, Li X, Xiao L
Animals : an open access journal from MDPI 2023 Dec 1;13(23)
Animals : an open access journal from MDPI 2023 Dec 1;13(23)
＜Editors' Choice＞ Supernatant from activated omentum accelerates wound healing in diabetic mice wound model.
Li Y, Hashikawa K, Ebisawa K, Kambe M, Higuchi S, Kamei Y
Nagoya journal of medical science 2023 Aug;85(3):528-541
Nagoya journal of medical science 2023 Aug;85(3):528-541
Dipeptidase‑2 is a prognostic marker in lung adenocarcinoma that is correlated with its sensitivity to cisplatin.
Wang Y, Zhang T, Du H, Yang M, Xie G, Liu T, Deng S, Yuan W, He S, Wu D, Xu Y
Oncology reports 2023 Aug;50(2)
Oncology reports 2023 Aug;50(2)
Testosterone attenuates senile cavernous fibrosis by regulating TGFβR1 and galectin-1 signaling pathways through miR-22-3p.
Hu Z, Zhang Y, Chen J, Luo M, Wang N, Xiao Y, He Q
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
Molecular and cellular biochemistry 2023 Aug;478(8):1791-1802
Salvianolic Acid B Attenuates Hypertrophic Scar Formation In Vivo and In Vitro.
Chong CH, Sun JM, Liu YX, Tsai YT, Zheng DN, Zhang YF, Yu L
Aesthetic plastic surgery 2023 Aug;47(4):1587-1597
Aesthetic plastic surgery 2023 Aug;47(4):1587-1597
sST2: A Bridge Between Sirt1/p53/p21 Signal-Induced Senescence and TGF-β1/Smad2/3 Regulation of Cardiac Fibrosis in Mouse Viral Myocarditis.
Tan J, Wei J, Lu H
Inflammation 2023 Aug;46(4):1305-1317
Inflammation 2023 Aug;46(4):1305-1317
Transcription factor 21 accelerates vascular calcification in mice by activating the IL-6/STAT3 signaling pathway and the interplay between VSMCs and ECs.
Zhao XK, Zhu MM, Wang SN, Zhang TT, Wei XN, Wang CY, Zheng J, Zhu WY, Jiang MX, Xu SW, Yang XX, Duan YJ, Zhang BC, Han JH, Miao QR, Hu H, Chen YL
Acta pharmacologica Sinica 2023 Aug;44(8):1625-1636
Acta pharmacologica Sinica 2023 Aug;44(8):1625-1636
Kangfuxin Accelerates Extraction Socket Healing by Promoting Angiogenesis Via Upregulation of CCL2 in Stem Cells.
Gao ZR, Zhou YH, Zhao YQ, Zhao J, Ye Q, Zhang SH, Feng Y, Tan L, Liu Q, Chen Y, Ouyang ZY, Hu J, Dusenge MA, Feng YZ, Guo Y
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2023 Aug;38(8):1208-1221
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2023 Aug;38(8):1208-1221
Thymosin β4 Exerts a Cytoprotective Function and Attenuates Liver Injury in Murine Hepatic Sinusoidal Obstruction Syndrome after Hematopoietic Stem Cell Transplantation.
Wang X, Zhou Y, Sun Q, Zhang Q, Zhou H, Zhang J, Du Y, Wang Y, Yuan K, Xu L, Zhang M, Yan D, Zeng L, Xu K, Sang W
Transplantation and cellular therapy 2023 Aug;29(8):492.e1-492.e10
Transplantation and cellular therapy 2023 Aug;29(8):492.e1-492.e10
Sustained release of magnesium and zinc ions synergistically accelerates wound healing.
Yang F, Xue Y, Wang F, Guo D, He Y, Zhao X, Yan F, Xu Y, Xia D, Liu Y
Bioactive materials 2023 Aug;26:88-101
Bioactive materials 2023 Aug;26:88-101
Crosstalk between Interleukin-1 Receptor-Like 1 and Transforming Growth Factor-β Receptor Signaling Promotes Renal Fibrosis.
Zhu X, Lu J, Rao J, Ru D, Gao M, Shi D, Cao K, Wen S, Dai C, Wang X, Mi W, Liu L, Zhou H
The American journal of pathology 2023 Aug;193(8):1029-1045
The American journal of pathology 2023 Aug;193(8):1029-1045
p53 deacetylation alleviates calcium oxalate deposition-induced renal fibrosis by inhibiting ferroptosis.
Ye Z, Xia Y, Li L, Li B, Chen L, Yu W, Ruan Y, Rao T, Zhou X, Cheng F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114925
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114925
Ginsenoside Rg1 ameliorates hypoxia-induced pulmonary arterial hypertension by inhibiting endothelial-to-mesenchymal transition and inflammation by regulating CCN1.
Tang BL, Liu Y, Zhang JL, Lu ML, Wang HX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114920
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114920
Genetic and pharmacological inhibition of METTL3 alleviates renal fibrosis by reducing EVL m6A modification through an IGF2BP2-dependent mechanism.
Ni WJ, Zhou H, Lu H, Ma NN, Hou BB, Li W, Kong FX, Yu JT, Hou R, Jin J, Wen JG, Zhang T, Meng XM
Clinical and translational medicine 2023 Aug;13(8):e1359
Clinical and translational medicine 2023 Aug;13(8):e1359
Amelioratory effects of astragaloside IV on hepatocarcinogenesis via Nrf2-mediated pSmad3C/3L transformation.
Fang Gong Y, Hou S, Xu JC, Chen Y, Zhu LL, Xu YY, Chen YQ, Li MM, Li LL, Yang JJ, Yang Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Aug;117:154903
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Aug;117:154903
Low molecular weight heparin synergistically enhances the efficacy of adoptive and anti-PD-1-based immunotherapy by increasing lymphocyte infiltration in colorectal cancer.
Quan Y, He J, Zou Q, Zhang L, Sun Q, Huang H, Li W, Xie K, Wei F
Journal for immunotherapy of cancer 2023 Aug;11(8)
Journal for immunotherapy of cancer 2023 Aug;11(8)
NQO1 alleviates renal fibrosis by inhibiting the TLR4/NF-κB and TGF-β/Smad signaling pathways in diabetic nephropathy.
Qiu D, Song S, Chen N, Bian Y, Yuan C, Zhang W, Duan H, Shi Y
Cellular signalling 2023 Aug;108:110712
Cellular signalling 2023 Aug;108:110712
N-acetyltransferase 10 promotes cutaneous wound repair via the NF-κB-IL-6 axis.
Wang B, Zhang J, Li G, Xu C, Yang L, Zhang J, Wu Y, Liu Y, Liu Z, Wang M, Li J, Tang X, Liu B
Cell death discovery 2023 Aug 29;9(1):324
Cell death discovery 2023 Aug 29;9(1):324
Baricitinib improves pulmonary fibrosis in mice with rheumatoid arthritis-associated interstitial lung disease by inhibiting the Jak2/Stat3 signaling pathway.
Liu H, Yang Y, Zhang J, Li X
Advances in rheumatology (London, England) 2023 Aug 28;63(1):45
Advances in rheumatology (London, England) 2023 Aug 28;63(1):45
CXCL8 Promotes Endothelial-to-Mesenchymal Transition of Endothelial Cells and Protects Cells from Erastin-Induced Ferroptosis via CXCR2-Mediated Activation of the NF-κB Signaling Pathway.
Ji HZ, Chen L, Ren M, Li S, Liu TY, Chen HJ, Yu HH, Sun Y
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Pharmaceuticals (Basel, Switzerland) 2023 Aug 25;16(9)
Single cell transcriptomic analyses implicate an immunosuppressive tumor microenvironment in pancreatic cancer liver metastasis.
Zhang S, Fang W, Zhou S, Zhu D, Chen R, Gao X, Li Z, Fu Y, Zhang Y, Yang F, Zhao J, Wu H, Wang P, Shen Y, Shen S, Xu G, Wang L, Yan C, Zou X, Chen D, Lv Y
Nature communications 2023 Aug 23;14(1):5123
Nature communications 2023 Aug 23;14(1):5123
Exosomal miR-103a-3p from Crohn's Creeping Fat-Derived Adipose-Derived Stem Cells Contributes to Intestinal Fibrosis by Targeting TGFBR3 and Activating Fibroblasts.
Qian W, Xu Y, Wen W, Huang L, Guo Z, Zhu W, Li Y
Journal of Crohn's & colitis 2023 Aug 21;17(8):1291-1308
Journal of Crohn's & colitis 2023 Aug 21;17(8):1291-1308
UCP1 alleviates renal interstitial fibrosis progression through oxidative stress pathway mediated by SIRT3 protein stability.
Xiong W, Xiong Z, Song A, Lei C, Ye C, Su H, Zhang C
Journal of translational medicine 2023 Aug 2;21(1):521
Journal of translational medicine 2023 Aug 2;21(1):521
Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling.
Liu X, Li J, Yang X, Li X, Kong J, Qi D, Zhang F, Sun B, Liu Y, Liu T
International journal of oral science 2023 Aug 2;15(1):32
International journal of oral science 2023 Aug 2;15(1):32
Targeting phenylpyruvate restrains excessive NLRP3 inflammasome activation and pathological inflammation in diabetic wound healing.
Lv D, Cao X, Zhong L, Dong Y, Xu Z, Rong Y, Xu H, Wang Z, Yang H, Yin R, Chen M, Ke C, Hu Z, Deng W, Tang B
Cell reports. Medicine 2023 Aug 15;4(8):101129
Cell reports. Medicine 2023 Aug 15;4(8):101129
TNFSF14/LIGHT promotes cardiac fibrosis and atrial fibrillation vulnerability via PI3Kγ/SGK1 pathway-dependent M2 macrophage polarisation.
Wu Y, Zhan S, Chen L, Sun M, Li M, Mou X, Zhang Z, Xu L, Xu Y
Journal of translational medicine 2023 Aug 14;21(1):544
Journal of translational medicine 2023 Aug 14;21(1):544
METTL14 reverses liver fibrosis by inhibiting NOVA2 through an m6A-YTHDF2-dependent mechanism.
Hou X, Li Y, Song J, Peng L, Zhang W, Liu R, Yuan H, Feng T, Li J, Li W, Zhu C
Hepatology communications 2023 Aug 1;7(8)
Hepatology communications 2023 Aug 1;7(8)
Effect of roflumilast on airway remodeling in asthmatic mice exposed to or not exposed to cigarette smoke: Comparison with the effect of dexamethasone.
Takeda Y, Takahashi M, Fuchikami JI, Nakamura H, Aoshiba K
Pulmonary pharmacology & therapeutics 2023 Apr;79:102198
Pulmonary pharmacology & therapeutics 2023 Apr;79:102198
MicroRNA-146a Promotes Embryonic Stem Cell Differentiation towards Vascular Smooth Muscle Cells through Regulation of Kruppel-like Factor 4.
Zhang Q, Pan RR, Wu YT, Wei YM
Current medical science 2023 Apr;43(2):223-231
Current medical science 2023 Apr;43(2):223-231
Myocardin Reverses Hypoxia-Inducible Factor-1α Mediated Phenotypic Modulation of Corpus Cavernosum Smooth Muscle Cells in Hypoxia Induced by Cobalt Chloride.
Zhou X, Luo C, Fan J, Gao G, Wang T, Zhang H, Wei A
The world journal of men's health 2023 Apr;41(2):363-372
The world journal of men's health 2023 Apr;41(2):363-372
Restoration of Sinusoid Fenestrae Followed by Targeted Nanoassembly Delivery of an Anti-Fibrotic Agent Improves Treatment Efficacy in Liver Fibrosis.
Li F, Zhao Y, Cheng Z, Wang Y, Yue Y, Cheng X, Sun J, Atabakhshi-Kashi M, Yao J, Dou J, Yu J, Zhang X, Qi Y, Li X, Qi X, Nie G
Advanced materials (Deerfield Beach, Fla.) 2023 Apr;35(17):e2212206
Advanced materials (Deerfield Beach, Fla.) 2023 Apr;35(17):e2212206
Biomimetic nanoparticles drive the mechanism understanding of shear-wave elasticity stiffness in triple negative breast cancers to predict clinical treatment.
Zheng D, Zhou J, Qian L, Liu X, Chang C, Tang S, Zhang H, Zhou S
Bioactive materials 2023 Apr;22:567-587
Bioactive materials 2023 Apr;22:567-587
Breach of tolerance versus burden of bile acids: Resolving the conundrum in the immunopathogenesis and natural history of primary biliary cholangitis.
Yamashita M, Honda A, Shimoyama S, Umemura M, Ohta K, Chida T, Noritake H, Kurono N, Ichimura-Shimizu M, Tsuneyama K, Miyazaki T, Tanaka A, Leung PSC, Gershwin ME, Suda T, Kawata K
Journal of autoimmunity 2023 Apr;136:103027
Journal of autoimmunity 2023 Apr;136:103027
A novel co-culture assay to evaluate the effects of sympathetic innervation on vascular smooth muscle differentiation.
Jafarkhani S, Khakbiz M, Amoabediny G, Mohammadi J, Tahmasebipour M, Rabbani H, Salimi A, Lee KB
Bioorganic chemistry 2023 Apr;133:106233
Bioorganic chemistry 2023 Apr;133:106233
Fate mapping RNA-sequencing reveal Malat1 regulates Sca1(+) progenitor cells to vascular smooth muscle cells transition in vascular remodeling.
Lyu L, Li Z, Wen Z, He Y, Wang X, Jiang L, Zhou X, Huang C, Wu Y, Chen T, Guo X
Cellular and molecular life sciences : CMLS 2023 Apr 6;80(5):118
Cellular and molecular life sciences : CMLS 2023 Apr 6;80(5):118
Active ingredients screening and pharmacological mechanism research of curcumae rhizoma-sparganii rhizoma herb pair ameliorates liver fibrosis based on network pharmacology.
Hao M, Yao Z, Zhao M, Chen Z, Wang P, Sang X, Yang Q, Wang K, Han X, Cao G
Journal of ethnopharmacology 2023 Apr 6;305:116111
Journal of ethnopharmacology 2023 Apr 6;305:116111
SCAP contributes to embryonic angiogenesis by negatively regulating KISS-1 expression in mice.
Zheng G, Su Y, Wei L, Yao Y, Wang Y, Luo X, Wang X, Ruan XZ, Li D, Chen Y
Cell death & disease 2023 Apr 6;14(4):249
Cell death & disease 2023 Apr 6;14(4):249
Continuous Monochromatic Blue Light Exacerbates High-Fat Diet-Induced Kidney Injury via Corticosterone-Mediated Oxidative Stress.
Ren W, Wang Z, Cao J, Dong Y, Wang T, Chen Y
Antioxidants (Basel, Switzerland) 2023 Apr 28;12(5)
Antioxidants (Basel, Switzerland) 2023 Apr 28;12(5)
Activation of NRF2 Signaling Pathway Delays the Progression of Hyperuricemic Nephropathy by Reducing Oxidative Stress.
Qiao P, Sun Y, Wang Y, Lin S, An Y, Wang L, Liu J, Huang Y, Yang B, Zhou H
Antioxidants (Basel, Switzerland) 2023 Apr 28;12(5)
Antioxidants (Basel, Switzerland) 2023 Apr 28;12(5)
Establishment of a Rat Model of Liver Venous Deprivation: Simultaneous Portal and Hepatic Vein Ligation.
Zhang Y, He X, Ma P, Xiong L, Bai W, Zhang G, Xu Y, Song W, Yu K
Journal of clinical and translational hepatology 2023 Apr 28;11(2):393-404
Journal of clinical and translational hepatology 2023 Apr 28;11(2):393-404
Two-Pore-Domain Potassium Channel TREK-1 Mediates Pulmonary Fibrosis through Macrophage M2 Polarization and by Direct Promotion of Fibroblast Differentiation.
Zhang Y, Fu J, Han Y, Feng D, Yue S, Zhou Y, Luo Z
Biomedicines 2023 Apr 26;11(5)
Biomedicines 2023 Apr 26;11(5)
Jia-Wei-Si-Miao-Yong-An Fang stimulates the healing of acute radiation-induced cutaneous wounds through MAPK/ERK pathway.
Wang Y, Gao J, Sun L, Li Q, Kang N, Gao C, Li T
Journal of ethnopharmacology 2023 Apr 24;306:116180
Journal of ethnopharmacology 2023 Apr 24;306:116180
Synergistic effect of constituent drugs of Baibutang on improving Yin-deficiency pulmonary fibrosis in rats.
Fu S, Song X, Tang X, Qian X, Du Z, Hu Y, Xu X, Zhang M
Journal of ethnopharmacology 2023 Apr 24;306:116050
Journal of ethnopharmacology 2023 Apr 24;306:116050
Progerinin, an Inhibitor of Progerin, Alleviates Cardiac Abnormalities in a Model Mouse of Hutchinson-Gilford Progeria Syndrome.
Kang SM, Seo S, Song EJ, Kweon O, Jo AH, Park S, Woo TG, Kim BH, Oh GT, Park BJ
Cells 2023 Apr 24;12(9)
Cells 2023 Apr 24;12(9)
Histone lactylation driven by mROS-mediated glycolytic shift promotes hypoxic pulmonary hypertension.
Chen J, Zhang M, Liu Y, Zhao S, Wang Y, Wang M, Niu W, Jin F, Li Z
Journal of molecular cell biology 2023 Apr 20;14(12)
Journal of molecular cell biology 2023 Apr 20;14(12)
Brevilin A is a potent anti-metastatic CRC agent that targets the VEGF-IL6-STAT3 axis in the HSCs-CRC interplay.
Fan X, Meng M, Li B, Chen H, Tan J, Xu K, Xiao S, Kwan HY, Liu Z, Su T
Journal of translational medicine 2023 Apr 16;21(1):260
Journal of translational medicine 2023 Apr 16;21(1):260
GL-V9 ameliorates liver fibrosis by inhibiting TGF-β/smad pathway.
Guo Y, Tian G, Chen X, Hou Y, Zhang X, Xue X, Zhao L, Wu Y
Experimental cell research 2023 Apr 1;425(1):113521
Experimental cell research 2023 Apr 1;425(1):113521
Selective Inhibition of Histone Deacetylase Class IIa With MC1568 Ameliorates Podocyte Injury.
He X, Sun T, Zhang P, Xia Z, Gao C, Ren H, Ji D
Frontiers in medicine 2022;9:848938
Frontiers in medicine 2022;9:848938
Deciphering Key Foreign Body Reaction-Related Transcription Factors and Genes Through Transcriptome Analysis.
Liu W, Xiong S, Du J, Song Y, Wang T, Zhang Y, Dong C, Huang Z, He Q, Yu Z, Ma X
Frontiers in molecular biosciences 2022;9:843391
Frontiers in molecular biosciences 2022;9:843391
Establishment of a New Abdominal Aortic Aneurysm Model in Rats by a Retroperitoneal Approach.
Zhu JX, Tang QQ, Zhou C, Shi XC, Yi SY, Yang Y
Frontiers in cardiovascular medicine 2022;9:808732
Frontiers in cardiovascular medicine 2022;9:808732
Anti-fibrotic effect of extracellular vesicles derived from tea leaves in hepatic stellate cells and liver fibrosis mice.
Gong Q, Zeng Z, Jiang T, Bai X, Pu C, Hao Y, Guo Y
Frontiers in nutrition 2022;9:1009139
Frontiers in nutrition 2022;9:1009139
Hepatoblastoma: Derived Exosomal LncRNA NEAT1 Induces BMSCs Differentiation into Tumor-Supporting Myofibroblasts via Modulating the miR-132/MMP9 Axis.
Hu Y, Zai H, Jiang W, Ou Z, Yao Y, Zhu Q
Journal of oncology 2022;2022:7630698
Journal of oncology 2022;2022:7630698
C/EBPα-Mediated Transcriptional Activation of PIK3C2A Regulates Autophagy, Matrix Metalloproteinase Expression, and Phenotypic of Vascular Smooth Muscle Cells in Aortic Dissection.
Lu H, Chen Y, Chen Y, Huang L, Chen L
Journal of immunology research 2022;2022:7465353
Journal of immunology research 2022;2022:7465353
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
Lin D, Zhang M, Luo C, Wei P, Cui K, Chen Z
Journal of immunology research 2022;2022:6833867
Journal of immunology research 2022;2022:6833867
Blocking REDD1/TXNIP Complex Ameliorates HG-Induced Renal Tubular Epithelial Cell Apoptosis and EMT through Repressing Oxidative Stress.
Mu L, Chen N, Chen Y, Yang Z, Zhou H, Song S, Shi Y
International journal of endocrinology 2022;2022:6073911
International journal of endocrinology 2022;2022:6073911
The Traditional Chinese Medicine Formula FTZ Protects against Cardiac Fibrosis by Suppressing the TGFβ1-Smad2/3 Pathway.
Zhang Y, Wang D, Wu K, Shao X, Diao H, Wang Z, Sun M, Huang X, Li Y, Tang X, Yan M, Guo J
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5642307
Evidence-based complementary and alternative medicine : eCAM 2022;2022:5642307
Hsa_circRNA_0008028 Deficiency Ameliorates High Glucose-Induced Proliferation, Calcification, and Autophagy of Vascular Smooth Muscle Cells via miR-182-5p/TRIB3 Axis.
Shi L, Li Y, Shi M, Li X, Li G, Cen J, Liu D, Wei C, Lin Y
Oxidative medicine and cellular longevity 2022;2022:5142381
Oxidative medicine and cellular longevity 2022;2022:5142381
p16(INK4a) Plays Critical Role in Exacerbating Inflammaging in High Fat Diet Induced Skin.
Liang Y, Gu T, Peng S, Lin Y, Liu J, Wang X, Huang X, Zhang X, Zhu J, Zhao L, Fan C, Wang G, Gu X, Lin J
Oxidative medicine and cellular longevity 2022;2022:3415528
Oxidative medicine and cellular longevity 2022;2022:3415528
HBO1 as an Important Target for the Treatment of CCL4-Induced Liver Fibrosis and Aged-Related Liver Aging and Fibrosis.
Xing B, Lan H, Li H
Oxidative medicine and cellular longevity 2022;2022:1881519
Oxidative medicine and cellular longevity 2022;2022:1881519
Qufeng Xuanbi Formula Ameliorates Airway Remodeling in Asthmatic Mice by Suppressing Airway Smooth Muscle Cell Proliferation through MEK/ERK Signaling Pathway.
Wang B, Tang L, Shi S, Yang Y, Sun X, Zhang X, Liu C, Liu L
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1525110
Evidence-based complementary and alternative medicine : eCAM 2022;2022:1525110
Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.
Zhang M, Lin D, Luo C, Wei P, Cui K, Chen Z
Oxidative medicine and cellular longevity 2022;2022:1247806
Oxidative medicine and cellular longevity 2022;2022:1247806
Blockade of SK4 channels suppresses atrial fibrillation by attenuating atrial fibrosis in canines with prolonged atrial pacing.
Wang Y, Yao Y, Ma Y, He S, Yang M, Cao Z, Liudi S, Fu Y, Chen H, Wang X, Huang C, Zhao Q
International journal of medical sciences 2022;19(14):1995-2007
International journal of medical sciences 2022;19(14):1995-2007
Commensal microbe-derived SCFA alleviates atrial fibrillation via GPR43/NLRP3 signaling.
Zuo K, Fang C, Liu Z, Fu Y, Liu Y, Liu L, Wang Y, Yin X, Liu X, Li J, Zhong J, Chen M, Xu L, Yang X
International journal of biological sciences 2022;18(10):4219-4232
International journal of biological sciences 2022;18(10):4219-4232
Knockdown of CD146 promotes endothelial-to-mesenchymal transition via Wnt/β-catenin pathway.
Zhang ZY, Zhai C, Yang XY, Li HB, Wu LL, Li L
PloS one 2022;17(8):e0273542
PloS one 2022;17(8):e0273542
The conditioned medium from mesenchymal stromal cells pretreated with proinflammatory cytokines promote fibroblasts migration and activation.
Liu C, Wang C, Yang F, Lu Y, Du P, Hu K, Yin X, Zhao P, Lu G
PloS one 2022;17(4):e0265049
PloS one 2022;17(4):e0265049
Exosome Derived from Mesenchymal Stem Cells Alleviates Pathological Scars by Inhibiting the Proliferation, Migration and Protein Expression of Fibroblasts via Delivering miR-138-5p to Target SIRT1.
Zhao W, Zhang R, Zang C, Zhang L, Zhao R, Li Q, Yang Z, Feng Z, Zhang W, Cui R
International journal of nanomedicine 2022;17:4023-4038
International journal of nanomedicine 2022;17:4023-4038
Didymin Ameliorates Liver Fibrosis by Alleviating Endoplasmic Reticulum Stress and Glycerophospholipid Metabolism: Based on Transcriptomics and Metabolomics.
Li Y, Li C, Xiong Y, Fang B, Lin X, Huang Q
Drug design, development and therapy 2022;16:1713-1729
Drug design, development and therapy 2022;16:1713-1729
Regenerative Peripheral Nerve Interfaces Effectively Prevent Neuroma Formation After Sciatic Nerve Transection in Rats.
Wu J, Zhang Y, Zhang X, Lin Z, Li G
Frontiers in molecular neuroscience 2022;15:938930
Frontiers in molecular neuroscience 2022;15:938930
Metformin Ameliorates Epithelial-Mesenchymal Transition of Renal Tubular Epithelial Cells in Diabetes by Increasing Vitamin D Receptor Expression.
Wen W, Huang B, Ye S
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:4001-4010
Diabetes, metabolic syndrome and obesity : targets and therapy 2022;15:4001-4010
Macrophage SCAP Contributes to Metaflammation and Lean NAFLD by Activating STING-NF-κB Signaling Pathway.
Huang X, Yao Y, Hou X, Wei L, Rao Y, Su Y, Zheng G, Ruan XZ, Li D, Chen Y
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
Cellular and molecular gastroenterology and hepatology 2022;14(1):1-26
Heidihuangwan alleviates renal fibrosis in rats with 5/6 nephrectomy by inhibiting autophagy.
Li YY, Tian ZH, Pan GH, Zhao P, Pan DJ, Zhang JQ, Ye LY, Zhang FR, Xu XD
Frontiers in pharmacology 2022;13:977284
Frontiers in pharmacology 2022;13:977284
Endoglin aggravates peritoneal fibrosis by regulating the activation of TGF-β/ALK/Smads signaling.
Huang Q, Xiao R, Lu J, Zhang Y, Xu L, Gao J, Sun J, Wang H
Frontiers in pharmacology 2022;13:973182
Frontiers in pharmacology 2022;13:973182
Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis.
Li F, Wang Y, Tian J, Zhou Z, Yin W, Qin X, Wang H, Zeng T, Li A, Jiang J
Frontiers in pharmacology 2022;13:962770
Frontiers in pharmacology 2022;13:962770
TIM-4 in macrophages contributes to nasal polyp formation through the TGF-β1-mediated epithelial to mesenchymal transition in nasal epithelial cells.
Qin D, Liu P, Zhou H, Jin J, Gong W, Liu K, Chen S, Huang J, Fan W, Tao Z, Xu Y
Frontiers in immunology 2022;13:941608
Frontiers in immunology 2022;13:941608
Inhibition of HDAC6 With CAY10603 Ameliorates Diabetic Kidney Disease by Suppressing NLRP3 Inflammasome.
Hou Q, Kan S, Wang Z, Shi J, Zeng C, Yang D, Jiang S, Liu Z
Frontiers in pharmacology 2022;13:938391
Frontiers in pharmacology 2022;13:938391
Ganfule capsule alleviates bile duct ligation-induced liver fibrosis in mice by inhibiting glutamine metabolism.
Ke C, Gao J, Tu J, Wang Y, Xiao Y, Wu Y, Liu Y, Zhou Z
Frontiers in pharmacology 2022;13:930785
Frontiers in pharmacology 2022;13:930785
Akkermansia muciniphila Alters Gut Microbiota and Immune System to Improve Cardiovascular Diseases in Murine Model.
He X, Bai Y, Zhou H, Wu K
Frontiers in microbiology 2022;13:906920
Frontiers in microbiology 2022;13:906920
Beneficial Effect of Edoxaban on Preventing Atrial Fibrillation and Coagulation by Reducing Inflammation via HBG1/HBD Biomarkers.
Yang C, Wang X, Guo Y, Meng X, Li Y, Xia C, Meng L, Dong M, Wang F
Frontiers in pharmacology 2022;13:904317
Frontiers in pharmacology 2022;13:904317
Mechanism of Endoplasmic Reticulum Stress Pathway in the Osteogenic Phenotypic Transformation of Aortic Valve Interstitial Cells.
Tao Y, Geng Y, Dang W, Xu X, Zhao H, Zou L, Li Y
Frontiers in endocrinology 2022;13:856331
Frontiers in endocrinology 2022;13:856331
Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway.
Li Z, Geng J, Xie B, He J, Wang J, Peng L, Hu Y, Dai H, Wang C
Frontiers in pharmacology 2022;13:834604
Frontiers in pharmacology 2022;13:834604
Atorvastatin Restores PPARα Inhibition of Lipid Metabolism Disorders by Downregulating miR-21 Expression to Improve Mitochondrial Function and Alleviate Diabetic Nephropathy Progression.
Xiang J, Zhang H, Zhou X, Wang D, Chen R, Tan W, Liang L, Shi M, Zhang F, Xiao Y, Zhou Y, Wang Y, Guo B
Frontiers in pharmacology 2022;13:819787
Frontiers in pharmacology 2022;13:819787
Diallyl Trisulfide Enhances the Survival of Multiterritory Perforator Skin Flaps.
Dong C, Chen Z, Zhu L, Bsoul N, Wu H, Jiang J, Chen X, Lai Y, Yu G, Gu Y, Guo X, Gao W
Frontiers in pharmacology 2022;13:809034
Frontiers in pharmacology 2022;13:809034
Tormentic Acid Ameliorates Hepatic Fibrosis in vivo by Inhibiting Glycerophospholipids Metabolism and PI3K/Akt/mTOR and NF-κB Pathways: Based on Transcriptomics and Metabolomics.
Lin X, Wei Y, Li Y, Xiong Y, Fang B, Li C, Huang Q, Huang R, Wei J
Frontiers in pharmacology 2022;13:801982
Frontiers in pharmacology 2022;13:801982
Long Noncoding RNA Metastasis-Associated Lung Adenocarcinoma Transcript 1 in Extracellular Vesicles Promotes Hepatic Stellate Cell Activation, Liver Fibrosis and β-Catenin Signaling Pathway.
Wang T, Zhang C, Meng X, Zhu B, Wang S, Yuan W, Zhang S, Xu J, Zhang C
Frontiers in physiology 2022;13:792182
Frontiers in physiology 2022;13:792182
Loss of DRO1/CCDC80 in the tumor microenvironment promotes carcinogenesis.
Christian JI, Pastula A, Herbst A, Neumann J, Marschall MK, Ofner A, Zierahn H, Schneider MR, Wolf E, Quante M, Kolligs FT
Oncotarget 2022;13:615-627
Oncotarget 2022;13:615-627
Yao medicine Amydrium hainanense suppresses hepatic fibrosis by repressing hepatic stellate cell activation via STAT3 signaling.
Wu B, Huang L, Wang Y, Zeng L, Lin Y, Li J, Wang S, Zhang G, An L
Frontiers in pharmacology 2022;13:1043022
Frontiers in pharmacology 2022;13:1043022
Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway.
Zhou C, Kuang Y, Li Q, Duan Y, Liu X, Yue J, Chen X, Liu J, Zhang Y, Zhang L
Theranostics 2022;12(11):5172-5188
Theranostics 2022;12(11):5172-5188
Norepinephrine acting on adventitial fibroblasts stimulates vascular smooth muscle cell proliferation via promoting small extracellular vesicle release.
Ye C, Zheng F, Xu T, Wu N, Tong Y, Xiong XQ, Zhou YB, Wang JJ, Chen Q, Li YH, Zhu GQ, Han Y
Theranostics 2022;12(10):4718-4733
Theranostics 2022;12(10):4718-4733
Irradiation enhances the malignancy-promoting behaviors of cancer-associated fibroblasts.
Zhang Z, Dong Y, Wu B, Li Y, Liu Z, Liu Z, Gao Y, Gao L, Song Q, Zheng Z, Yao Y
Frontiers in oncology 2022;12:965660
Frontiers in oncology 2022;12:965660
Fibroblasts mediate the angiogenesis of pheochromocytoma by increasing COX4I2 expression.
Mao Y, Zhuo R, Ma W, Dai J, Alimu P, Fang C, Xu D, Ye L, Wang W, Sun F
Frontiers in oncology 2022;12:938123
Frontiers in oncology 2022;12:938123
Resveratrol ameliorates iron overload induced liver fibrosis in mice by regulating iron homeostasis.
Wang H, Jiang C, Yang Y, Li J, Wang Y, Wang C, Gao Y
PeerJ 2022;10:e13592
PeerJ 2022;10:e13592
Curcumol alleviates liver fibrosis by inducing endoplasmic reticulum stress-mediated necroptosis of hepatic stellate cells through Sirt1/NICD pathway.
Sun S, Huan S, Li Z, Yao Y, Su Y, Xia S, Wang S, Xu X, Shao J, Zhang Z, Zhang F, Fu J, Zheng S
PeerJ 2022;10:e13376
PeerJ 2022;10:e13376
From hair to liver: emerging application of hair follicle mesenchymal stem cell transplantation reverses liver cirrhosis by blocking the TGF-β/Smad signaling pathway to inhibit pathological HSC activation.
Liu Q, Lv C, Jiang Y, Luo K, Gao Y, Liu J, Zhang X, Mohammad Omar J, Jin S
PeerJ 2022;10:e12872
PeerJ 2022;10:e12872
Lycorine Inhibits Hypertrophic Scar Formation by Inducing ROS-Mediated Apoptosis.
Dong Y, Lv D, Zhao Z, Xu Z, Hu Z, Tang B
Frontiers in bioengineering and biotechnology 2022;10:892015
Frontiers in bioengineering and biotechnology 2022;10:892015
Asiaticoside Combined With Carbon Ion Implantation to Improve the Biocompatibility of Silicone Rubber and to Reduce the Risk of Capsule Contracture.
Liu X, Song YJ, Chen X, Huang MY, Zhao CX, Zhou X, Zhou X
Frontiers in bioengineering and biotechnology 2022;10:810244
Frontiers in bioengineering and biotechnology 2022;10:810244
Macrophage derived miR-7219-3p-containing exosomes mediate fibroblast trans-differentiation by targeting SPRY1 in silicosis.
Niu Z, Wang L, Qin X, Ye Z, Xie B, Hu Y
Toxicology 2022 Sep;479:153310
Toxicology 2022 Sep;479:153310
Fatty acid-binding protein 5 aggravates pulmonary artery fibrosis in pulmonary hypertension secondary to left heart disease via activating wnt/β-catenin pathway.
Lei Q, Yu Z, Li H, Cheng J, Wang Y
Journal of advanced research 2022 Sep;40:197-206
Journal of advanced research 2022 Sep;40:197-206
Anti-angiogenic nano-delivery system promotes tumor vascular normalizing and micro-environment reprogramming in solid tumor.
Shen R, Peng L, Zhou W, Wang D, Jiang Q, Ji J, Hu F, Yuan H
Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:550-564
Journal of controlled release : official journal of the Controlled Release Society 2022 Sep;349:550-564
Substitution of SERCA2 Cys(674) accelerates aortic aneurysm by inducing endoplasmic reticulum stress and promoting cell apoptosis.
Wang L, Yang Z, Wang S, Que Y, Shu X, Wu F, Liu G, Li S, Hu P, Chen H, Shi J, Tong X
British journal of pharmacology 2022 Sep;179(17):4423-4439
British journal of pharmacology 2022 Sep;179(17):4423-4439
Hydroxyurea protects against diabetic cardiomyopathy by inhibiting inflammation and apoptosis.
Zhou Y, Lu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113291
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Sep;153:113291
N-Acetyl-l-tryptophan inhibits CCl(4)-induced hepatic fibrogenesis via regulating TGF-β1/SMAD and Hippo/YAP1 signal.
Ma T, Cheng H, Li T, Chen Y, Cai T, Bai J, Wu Z, Xia X, Liang T, Du Y, Fu W
Bioorganic chemistry 2022 Sep;126:105899
Bioorganic chemistry 2022 Sep;126:105899
Immunohistochemical analysis of PD-L1 and tumor-infiltrating immune cells expression in the tumor microenvironment of primary signet ring cell carcinoma of the prostate.
Teng QL, Yang XR, Wen S, Dai ZH, Wang HL, Liu TQ, Wang L, Fan B, Liu ZY
Asian journal of andrology 2022 Sep-Oct;24(5):525-532
Asian journal of andrology 2022 Sep-Oct;24(5):525-532
Metabonomics profile analysis in inflammation-induced preterm birth and the potential role of metabolites in regulating premature cervical ripening.
Yan Y, Gu Z, Li B, Guo X, Zhang Z, Zhang R, Bian Z, Qiu J
Reproductive biology and endocrinology : RB&E 2022 Sep 6;20(1):135
Reproductive biology and endocrinology : RB&E 2022 Sep 6;20(1):135
Alamandine alleviated heart failure and fibrosis in myocardial infarction mice.
Zhao K, Xu T, Mao Y, Wu X, Hua D, Sheng Y, Li P
Biology direct 2022 Sep 27;17(1):25
Biology direct 2022 Sep 27;17(1):25
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Wang ZC, Niu KM, Wu YJ, Du KR, Qi LW, Zhou YB, Sun HJ
Cell death & disease 2022 Sep 26;13(9):824
Cell death & disease 2022 Sep 26;13(9):824
miR-182-5p attenuates Schistosoma japonicum-induced hepatic fibrosis by targeting tristetraprolin.
Zhao X, Xia Z, Wang Z, Zhou M, Qiu X, Wang C, Xu T, Fang Q, Ming Z, Dong H
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
Acta biochimica et biophysica Sinica 2022 Sep 25;54(10):1421-1430
Leucine Supplementation in Middle-Aged Male Mice Improved Aging-Induced Vascular Remodeling and Dysfunction via Activating the Sirt1-Foxo1 Axis.
Hao Z, Xu G, Yuan M, Tan R, Xia Y, Liu Y, Yin X
Nutrients 2022 Sep 17;14(18)
Nutrients 2022 Sep 17;14(18)
Cyclodextrin boostered-high density lipoprotein for antiatherosclerosis by regulating cholesterol efflux and efferocytosis.
Wang Y, Gao H, Huang X, Chen Z, Kang P, Zhou Y, Qin D, Zhang W, Liu J
Carbohydrate polymers 2022 Sep 15;292:119632
Carbohydrate polymers 2022 Sep 15;292:119632
Studies of ultrastructure, gene expression, and marker analysis reveal that mouse bladder PDGFRA(+) interstitial cells are fibroblasts.
Clayton DR, Ruiz WG, Dalghi MG, Montalbetti N, Carattino MD, Apodaca G
American journal of physiology. Renal physiology 2022 Sep 1;323(3):F299-F321
American journal of physiology. Renal physiology 2022 Sep 1;323(3):F299-F321
Sphingosine 1-phosphate receptor 2 promotes erythrocyte clearance by vascular smooth muscle cells in intraplaque hemorrhage through MFG-E8 production.
Pan D, Wu W, Zuo G, Xie X, Li H, Ren X, Kong C, Zhou W, Zhang Z, Waterfall M, Chen S
Cellular signalling 2022 Oct;98:110419
Cellular signalling 2022 Oct;98:110419
Salt-inducible kinase 1 deficiency promotes vascular remodeling in pulmonary arterial hypertension via enhancement of yes-associated protein-mediated proliferation.
Pu J, Wang F, Ye P, Jiang X, Zhou W, Gu Y, Chen S
Heliyon 2022 Oct;8(10):e11016
Heliyon 2022 Oct;8(10):e11016
Anti-inflammatory potential of stevia residue extract against uric acid-associated renal injury in mice.
Mehmood A, Althobaiti F, Zhao L, Usman M, Chen X, Alharthi F, Soliman MM, Shah AA, Murtaza MA, Nadeem M, Ranjha MMAN, Wang C
Journal of food biochemistry 2022 Oct;46(10):e14286
Journal of food biochemistry 2022 Oct;46(10):e14286
Activating α7nAChR ameliorates abdominal aortic aneurysm through inhibiting pyroptosis mediated by NLRP3 inflammasome.
Fu H, Shen QR, Zhao Y, Ni M, Zhou CC, Chen JK, Chi C, Li DJ, Liang G, Shen FM
Acta pharmacologica Sinica 2022 Oct;43(10):2585-2595
Acta pharmacologica Sinica 2022 Oct;43(10):2585-2595
UFMylation Is Activated in Atherosclerosis of ApoE Knockout Mice.
Sun Y, Li W, Cao Z, Hu J, Jia M, Su M
DNA and cell biology 2022 Oct;41(10):871-878
DNA and cell biology 2022 Oct;41(10):871-878
Substitution of the SERCA2 Cys(674) reactive thiol accelerates atherosclerosis by inducing endoplasmic reticulum stress and inflammation.
Su H, Mei Y, Luo S, Wu H, He Y, Shiraishi Y, Hu P, Cohen RA, Tong X
British journal of pharmacology 2022 Oct;179(20):4778-4791
British journal of pharmacology 2022 Oct;179(20):4778-4791
Induction of GLI1 by miR-27b-3p/FBXW7/KLF5 pathway contributes to pulmonary arterial hypertension.
Wang Q, Chai L, Zhang Q, Wang J, Liu J, Chen H, Wang Y, Chen Y, Shen N, Xie X, Li M
Journal of molecular and cellular cardiology 2022 Oct;171:16-29
Journal of molecular and cellular cardiology 2022 Oct;171:16-29
Established new compound IMB16-4 self-emulsifying drug delivery systems for increasing oral bioavailability and enhancing anti-hepatic fibrosis effect.
Niu X, Meng Y, Wang Y, Li G
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113657
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113657
CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment.
Pan Z, Xu T, Bao L, Hu X, Jin T, Chen J, Chen J, Qian Y, Lu X, Li L, Zheng G, Zhang Y, Zou X, Song F, Zheng C, Jiang L, Wang J, Tan Z, Huang P, Ge M
Molecular cancer 2022 Oct 3;21(1):190
Molecular cancer 2022 Oct 3;21(1):190
A network pharmacology-based study on the mechanism of astragaloside IV alleviating renal fibrosis through the AKT1/GSK-3β pathway.
Yu X, Xiao Q, Yu X, Cheng Y, Lin H, Xiang Z
Journal of ethnopharmacology 2022 Oct 28;297:115535
Journal of ethnopharmacology 2022 Oct 28;297:115535
Vascular restenosis reduction with platelet membrane coated nanoparticle directed M2 macrophage polarization.
Li F, Rong Z, Zhang R, Niu S, Di X, Ni L, Liu C
iScience 2022 Oct 21;25(10):105147
iScience 2022 Oct 21;25(10):105147
Pharmacological targeting of cGAS/STING-YAP axis suppresses pathological angiogenesis and ameliorates organ fibrosis.
Wang L, Zhang Y, Ren Y, Yang X, Ben H, Zhao F, Yang S, Wang L, Qing J
European journal of pharmacology 2022 Oct 15;932:175241
European journal of pharmacology 2022 Oct 15;932:175241
Single-cell RNA-seq analysis of testicular somatic cell development in pigs.
Zhang L, Guo M, Liu Z, Liu R, Zheng Y, Yu T, Lv Y, Lu H, Zeng W, Zhang T, Pan C
Journal of genetics and genomics = Yi chuan xue bao 2022 Nov;49(11):1016-1028
Journal of genetics and genomics = Yi chuan xue bao 2022 Nov;49(11):1016-1028
Cancer-associated fibroblast-secreted miR-421 promotes pancreatic cancer by regulating the SIRT3/H3K9Ac/HIF-1α axis.
Zhou B, Lei JH, Wang Q, Qu TF, Cha LC, Zhan HX, Liu SL, Hu X, Sun CD, Guo WD, Qiu FB, Cao JY
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092
The Kaohsiung journal of medical sciences 2022 Nov;38(11):1080-1092
Biomimetic cell membrane-coated glucose/oxygen-exhausting nanoreactor for remodeling tumor microenvironment in targeted hypoxic tumor therapy.
Guo H, Zhang W, Wang L, Shao Z, Huang X
Biomaterials 2022 Nov;290:121821
Biomaterials 2022 Nov;290:121821
Apigenin inhibits fibrous scar formation after acute spinal cord injury through TGFβ/SMADs signaling pathway.
Jin Z, Tian L, Zhang Y, Zhang X, Kang J, Dong H, Huang N, Pan L, Ning B
CNS neuroscience & therapeutics 2022 Nov;28(11):1883-1894
CNS neuroscience & therapeutics 2022 Nov;28(11):1883-1894
Apatinib Through Activating the RhoA/ROCK Signaling Pathway to Cause Dysfunction of Vascular Smooth Muscle Cells.
Wang W, He Q, Zhuang C, Zhang H, Fan X, Wang Q, Qi M, Sun R, Li C, Yu J
Applied biochemistry and biotechnology 2022 Nov;194(11):5367-5385
Applied biochemistry and biotechnology 2022 Nov;194(11):5367-5385
Extracellular vesicles from human urine-derived stem cells merged in hyaluronic acid ameliorate erectile dysfunction in type 2 diabetic rats by glans administration.
Zhuang J, Gao P, Chen H, Fang Z, Zheng J, Zhu D, Hou J
Andrology 2022 Nov;10(8):1673-1686
Andrology 2022 Nov;10(8):1673-1686
Aligned nanofibrous collagen membranes from fish swim bladder as a tough and acid-resistant suture for pH-regulated stomach perforation and tendon rupture.
Luan Z, Liu S, Wang W, Xu K, Ye S, Dan R, Zhang H, Shu Z, Wang T, Fan C, Xing M, Yang S
Biomaterials research 2022 Nov 8;26(1):60
Biomaterials research 2022 Nov 8;26(1):60
Pirfenidone-loaded exosomes derived from pancreatic ductal adenocarcinoma cells alleviate fibrosis of premetastatic niches to inhibit liver metastasis.
Zhao J, Zhu Y, Li Z, Liang J, Zhang Y, Zhou S, Zhang Y, Fan Z, Shen Y, Liu Y, Zhang F, Shen S, Xu G, Wang L, Lv Y, Zhang S, Zou X
Biomaterials science 2022 Nov 8;10(22):6614-6626
Biomaterials science 2022 Nov 8;10(22):6614-6626
The Impact of Sleep Disturbance on Gut Microbiota, Atrial Substrate, and Atrial Fibrillation Inducibility in Mice: A Multi-Omics Analysis.
Zuo K, Fang C, Fu Y, Liu Z, Liu Y, Liu L, Wang Y, Wang H, Yin X, Liu X, Li J, Zhong J, Chen M, Yang X, Xu L
Metabolites 2022 Nov 20;12(11)
Metabolites 2022 Nov 20;12(11)
Ovarian tumorB1-mediated heat shock transcription factor 1 deubiquitination is critical for glycolysis and development of endometriosis.
Ling X, Lu J, Wang X, Liu L, Liu L, Wang Y, Sun Y, Ren C, Lu C, Yu Z
iScience 2022 Nov 18;25(11):105363
iScience 2022 Nov 18;25(11):105363
A Shape-Adaptive Gallic Acid Driven Multifunctional Adhesive Hydrogel Loaded with Scolopin2 for Wound Repair.
Chen H, Zheng T, Wu C, Wang J, Ye F, Cui M, Sun S, Zhang Y, Li Y, Dong Z
Pharmaceuticals (Basel, Switzerland) 2022 Nov 17;15(11)
Pharmaceuticals (Basel, Switzerland) 2022 Nov 17;15(11)
Ultrastructural Characterization of Human Gingival Fibroblasts in 3D Culture.
Alfonso García SL, Mira Uribe LM, Castaño López S, Parada-Sanchez MT, Arboleda-Toro D
Cells 2022 Nov 17;11(22)
Cells 2022 Nov 17;11(22)
LncRNA Airn alleviates diabetic cardiac fibrosis by inhibiting activation of cardiac fibroblasts via a m6A-IMP2-p53 axis.
Peng T, Liu M, Hu L, Guo D, Wang D, Qi B, Ren G, Hu C, Zhang F, Chun HJ, Song L, Hu J, Li Y
Biology direct 2022 Nov 16;17(1):32
Biology direct 2022 Nov 16;17(1):32
Targeting glutamine metabolism in hepatic stellate cells alleviates liver fibrosis.
Yin X, Peng J, Gu L, Liu Y, Li X, Wu J, Xu B, Zhuge Y, Zhang F
Cell death & disease 2022 Nov 14;13(11):955
Cell death & disease 2022 Nov 14;13(11):955
S100A8-Mediated NLRP3 Inflammasome-Dependent Pyroptosis in Macrophages Facilitates Liver Fibrosis Progression.
Liu Y, Kong X, You Y, Xiang L, Zhang Y, Wu R, Zhou L, Duan L
Cells 2022 Nov 12;11(22)
Cells 2022 Nov 12;11(22)
Disulfiram ameliorates nonalcoholic steatohepatitis by modulating the gut microbiota and bile acid metabolism.
Lei Y, Tang L, Chen Q, Wu L, He W, Tu D, Wang S, Chen Y, Liu S, Xie Z, Wei H, Yang S, Tang B
Nature communications 2022 Nov 11;13(1):6862
Nature communications 2022 Nov 11;13(1):6862
NLRC3 deficiency promotes cutaneous wound healing due to the inhibition of p53 signaling.
Qin Y, Wu K, Zhang Z, Pan R, Lin Z, Zhang W, Huang S, Dai J, Huang R, Gong S, Lin H, Chong S, Lu L, Lu X
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166518
Biochimica et biophysica acta. Molecular basis of disease 2022 Nov 1;1868(11):166518
PEDF reduces malignant cells proliferation and inhibits the progression of myelofibrosis in myeloproliferative neoplasms.
Li Y, Gao H, Dong H, Wang W, Xu Z, Wang G, Liu Y, Wang H, Ju W, Qiao J, Xu K, Fu C, Zeng L
Biochemical pharmacology 2022 May;199:115013
Biochemical pharmacology 2022 May;199:115013
Sphk1 and Sphk2 Differentially Regulate Erythropoietin Synthesis in Mouse Renal Interstitial Fibroblast-like Cells.
Hafizi R, Imeri F, Stepanovska Tanturovska B, Manaila R, Schwalm S, Trautmann S, Wenger RH, Pfeilschifter J, Huwiler A
International journal of molecular sciences 2022 May 24;23(11)
International journal of molecular sciences 2022 May 24;23(11)
Cancer associated fibroblast-derived CCL5 promotes hepatocellular carcinoma metastasis through activating HIF1α/ZEB1 axis.
Xu H, Zhao J, Li J, Zhu Z, Cui Z, Liu R, Lu R, Yao Z, Xu Q
Cell death & disease 2022 May 20;13(5):478
Cell death & disease 2022 May 20;13(5):478
Accumulation of polystyrene microplastics induces liver fibrosis by activating cGAS/STING pathway.
Shen R, Yang K, Cheng X, Guo C, Xing X, Sun H, Liu D, Liu X, Wang D
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Environmental pollution (Barking, Essex : 1987) 2022 May 1;300:118986
Development and identification of a induced pluripotent stem cells line (SMBCi013-A) derived from urine cells of a patient with Wilson's disease.
Zhao Y, Cui Y, Luan J, Wang J, Shi L, Han Z, Han J
Stem cell research 2022 Mar;59:102650
Stem cell research 2022 Mar;59:102650
Kinsenoside attenuates liver fibro-inflammation by suppressing dendritic cells via the PI3K-AKT-FoxO1 pathway.
Xiang M, Liu T, Tian C, Ma K, Gou J, Huang R, Li S, Li Q, Xu C, Li L, Lee CH, Zhang Y
Pharmacological research 2022 Mar;177:106092
Pharmacological research 2022 Mar;177:106092
MicroRNA-130a attenuates cardiac fibrosis after myocardial infarction through TGF-β/Smad signaling by directly targeting TGF-β receptor 1.
Feng Y, Bao Y, Ding J, Li H, Liu W, Wang X, Guan H, Chen Z
Bioengineered 2022 Mar;13(3):5779-5791
Bioengineered 2022 Mar;13(3):5779-5791
P16ink4a overexpression ameliorates cardiac remodeling of mouse following myocardial infarction via CDK4/pRb pathway.
Shi J, Sun J, Liu L, Shan T, Meng H, Yang T, Wang S, Wei T, Chen B, Ma Y, Wang Q, Wang H, Liu J, Wang L
Biochemical and biophysical research communications 2022 Mar 5;595:62-68
Biochemical and biophysical research communications 2022 Mar 5;595:62-68
The SETD8/ELK1/bach1 complex regulates hyperglycaemia-mediated EndMT in diabetic nephropathy.
Li X, Lu L, Hou W, Wang F, Huang T, Meng Z, Zhu M
Journal of translational medicine 2022 Mar 29;20(1):147
Journal of translational medicine 2022 Mar 29;20(1):147
Ferroptosis, a new target for treatment of renal injury and fibrosis in a 5/6 nephrectomy-induced CKD rat model.
Wang J, Wang Y, Liu Y, Cai X, Huang X, Fu W, Wang L, Qiu L, Li J, Sun L
Cell death discovery 2022 Mar 22;8(1):127
Cell death discovery 2022 Mar 22;8(1):127
Exosomal let-7i-5p from three-dimensional cultured human umbilical cord mesenchymal stem cells inhibits fibroblast activation in silicosis through targeting TGFBR1.
Xu C, Hou L, Zhao J, Wang Y, Jiang F, Jiang Q, Zhu Z, Tian L
Ecotoxicology and environmental safety 2022 Mar 15;233:113302
Ecotoxicology and environmental safety 2022 Mar 15;233:113302
Knockdown of long noncoding RNA MIAT attenuates cigarette smoke-induced airway remodeling by downregulating miR-29c-3p-HIF3A axis.
Gu W, Wang L, Deng G, Gu X, Tang Z, Li S, Jin W, Yang J, Guo X, Li Q
Toxicology letters 2022 Mar 1;357:11-19
Toxicology letters 2022 Mar 1;357:11-19
Citri Reticulatae Pericarpium alleviates postmyocardial infarction heart failure by upregulating PPARγ expression.
Chen M, Zhu H, Zhu Q, Wu X, Zhou Y, Gao R, Shi M, Zhang T, Yin T, Zhang H, Shang H, Li X
Clinical and experimental pharmacology & physiology 2022 Jun;49(6):661-673
Clinical and experimental pharmacology & physiology 2022 Jun;49(6):661-673
Modification of lysine deacetylation regulates curcumol-induced necroptosis through autophagy in hepatic stellate cells.
Sun S, Li Z, Huan S, Kai J, Xia S, Su Y, Ji S, Chen A, Wang S, Xu X, Shao J, Zhang F, Zhang B, Zhang Z, Zheng S
Phytotherapy research : PTR 2022 Jun;36(6):2660-2676
Phytotherapy research : PTR 2022 Jun;36(6):2660-2676
CHIR99021 balance TGFβ1 induced human corneal endothelial-to-mesenchymal transition to favor corneal endothelial cell proliferation.
Wang Y, Jin C, Tian H, Xu J, Chen J, Hu S, Li Q, Lu L, Ou Q, Xu GT, Cui H
Experimental eye research 2022 Jun;219:108939
Experimental eye research 2022 Jun;219:108939
Gli(ko) BMSC: A potential strategy of treatment for renal fibrosis.
Shi L, Gao X, Bi Y, Li M, Sun H, Tian X, Bi W
Regenerative therapy 2022 Jun;20:157-164
Regenerative therapy 2022 Jun;20:157-164
Myelin-associated glycoprotein combined with chitin conduit inhibits painful neuroma formation after sciatic nerve transection.
Pi W, Li C, Zhang M, Zhang W, Zhang PX
Neural regeneration research 2022 Jun;17(6):1343-1347
Neural regeneration research 2022 Jun;17(6):1343-1347
Tracking the response to Pseudomonas aeruginosa infection in ozone-induced chronic obstructive pulmonary disease mouse models.
Han L, Huang Y, Fu Q, Xue Y, Ding F, Zhang M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112980
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Jun;150:112980
Molecular feature of arterial remodeling in the brain arteriovenous malformation revealed by arteriovenous shunt rat model and RNA sequencing.
Chen B, Tao W, Yan L, Zeng M, Song L, Huang Z, Chen F
International immunopharmacology 2022 Jun;107:108653
International immunopharmacology 2022 Jun;107:108653
Targeted inhibition of the immunoproteasome blocks endothelial MHC class II antigen presentation to CD4(+) T cells in chronic liver injury.
Zhang Y, Yang X, Bi T, Wu X, Wang L, Ren Y, Ou Y, Xie C, Li K, Ran H, Wang J, Zhao F, Shui P, Qing J
International immunopharmacology 2022 Jun;107:108639
International immunopharmacology 2022 Jun;107:108639
Capsaicin ameliorates renal fibrosis by inhibiting TGF-β1-Smad2/3 signaling.
Liu Z, Wang W, Li X, Tang S, Meng D, Xia W, Wang H, Wu Y, Zhou X, Zhang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154067
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154067
Hydroxychloroquine alleviates renal interstitial fibrosis by inhibiting the PI3K/Akt signaling pathway.
Li D, Yu K, Feng F, Zhang Y, Bai F, Zhang Y, Sun N, Fan J, Liu L, Yang H, Yang X
Biochemical and biophysical research communications 2022 Jun 25;610:154-161
Biochemical and biophysical research communications 2022 Jun 25;610:154-161
Erectile dysfunction in hypospadiac male adult rats induced by maternal exposure to di-n-butyl phthalate.
Zhou X, Wang S, Zhou R, Zhang T, Wang Y, Zhang Q, Cong R, Ji C, Luan J, Yao L, Zhou X, Song N
Toxicology 2022 Jun 15;475:153227
Toxicology 2022 Jun 15;475:153227
CUX1 promotes epithelial-mesenchymal transition (EMT) in renal fibrosis of UUO model by targeting MMP7.
Teng S, Liu G, Li L, Ou J, Yu Y
Biochemical and biophysical research communications 2022 Jun 11;608:128-134
Biochemical and biophysical research communications 2022 Jun 11;608:128-134
Spermidine Ameliorates Nonalcoholic Steatohepatitis through Thyroid Hormone-Responsive Protein Signaling and the Gut Microbiota-Mediated Metabolism of Bile Acids.
Ni Y, Hu Y, Lou X, Rong N, Liu F, Yang C, Zheng A, Yang S, Bao J, Fu Z
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6478-6492
Journal of agricultural and food chemistry 2022 Jun 1;70(21):6478-6492
Generation of a non-integrated induced pluripotent stem cell line from urine cells of a Chinese osteogenesis imperfecta type I patient.
Luan J, Cui Y, Wang J, Liang Y, Zhao Y, Zhang G, Han J
Stem cell research 2022 Jul;62:102827
Stem cell research 2022 Jul;62:102827
Generation of induced pluripotent stem cells named SMBCi019-A from a methylmalonic acidemia patient carrying the MMACHC mutations.
Luan J, Zou H, Cui Y, Wang J, Han Z, Zhang G, Han J
Stem cell research 2022 Jul;62:102821
Stem cell research 2022 Jul;62:102821
Establishment of a control induced pluripotent stem cell line SMBCi018-A from a patient with congenital talipes equinovarus.
Han Z, Wang J, Luan J, Cui Y, Han J
Stem cell research 2022 Jul;62:102814
Stem cell research 2022 Jul;62:102814
LncRNA LINC00961 regulates endothelial‑mesenchymal transition via the PTEN‑PI3K‑AKT pathway.
Hu JX, Zheng ZQ, Kang T, Qian W, Huang SH, Li BG
Molecular medicine reports 2022 Jul;26(1)
Molecular medicine reports 2022 Jul;26(1)
Asperuloside inhibited epithelial-mesenchymal transition in colitis associated cancer via activation of vitamin D receptor.
Lu Y, Guan T, Xu S, Chen YE, Shen Q, Zhu S, Liu Y, Liang J, Hou S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154070
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul;101:154070
Peptidome analysis of human intrauterine adhesion tissues and the identification of antifibrotic peptide.
Hua X, Zhang Y, Xu J, Xu L, Shi Y, Yang D, Gu X, Wang S, Jia X, Xu F, Chen J, Ying X
Journal of biomedical research 2022 Jul 28;36(4):280-296
Journal of biomedical research 2022 Jul 28;36(4):280-296
Albumin-induced premature senescence in human renal proximal tubular cells and its relationship with intercellular fibrosis.
Lu W, Ren S, Dong W, Li X, Zheng Z, Jia Y, Xue Y
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):893-903
Acta biochimica et biophysica Sinica 2022 Jul 25;54(7):893-903
Nintedanib Inhibits Endothelial Mesenchymal Transition in Bleomycin-Induced Pulmonary Fibrosis via Focal Adhesion Kinase Activity Reduction.
Yu WK, Chen WC, Su VY, Shen HC, Wu HH, Chen H, Yang KY
International journal of molecular sciences 2022 Jul 25;23(15)
International journal of molecular sciences 2022 Jul 25;23(15)
Interplay of Helicobacter pylori, fibroblasts, and cancer cells induces fibroblast activation and serpin E1 expression by cancer cells to promote gastric tumorigenesis.
Chen X, Chen W, Zhao Y, Wang Q, Wang W, Xiang Y, Yuan H, Xie Y, Zhou J
Journal of translational medicine 2022 Jul 21;20(1):322
Journal of translational medicine 2022 Jul 21;20(1):322
Identification of the active compounds and functional mechanisms of Jinshui Huanxian formula in pulmonary fibrosis by integrating serum pharmacochemistry with network pharmacology.
Shao D, Liu X, Wu J, Zhang A, Bai Y, Zhao P, Li J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154177
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jul 20;102:154177
Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney.
Taglienti M, Graf D, Schumacher V, Kreidberg JA
Development (Cambridge, England) 2022 Jul 15;149(14)
Development (Cambridge, England) 2022 Jul 15;149(14)
BMSC-derived exosomes protect against kidney injury through regulating klotho in 5/6 nephrectomy rats.
Wan F, Yang RC, Tang YW, Tang XL, Ye T, Zheng J, Zhang HQ, Lin Y
European journal of medical research 2022 Jul 11;27(1):118
European journal of medical research 2022 Jul 11;27(1):118
Monochromatic blue light not green light exposure is associated with continuous light-induced hepatic steatosis in high fat diet fed-mice via oxidative stress.
Guan Q, Wang Z, Cao J, Dong Y, Chen Y
Ecotoxicology and environmental safety 2022 Jul 1;239:113625
Ecotoxicology and environmental safety 2022 Jul 1;239:113625
The DR1‑CSE/H(2)S system inhibits renal fibrosis by downregulating the ERK1/2 signaling pathway in diabetic mice.
Li H, Sun F, Bai S, Chang G, Wu R, Wei Y, Wen X, Xi Y, Hao J, Zaid A
International journal of molecular medicine 2022 Jan;49(1)
International journal of molecular medicine 2022 Jan;49(1)
Histone methyltransferase DOT1L mediates the TGF-β1/Smad3 signaling pathway through epigenetic modification of SYK in myocardial infarction.
Li F, Li L, Zhang J, Yang X, Liu Y
Human cell 2022 Jan;35(1):98-110
Human cell 2022 Jan;35(1):98-110
Jolkinolide B alleviates renal fibrosis via anti-inflammation and inhibition of epithelial-mesenchymal transition in unilateral ureteral obstruction mice.
Li M, Yan Y, He J, Wang YM, Guo YX, Wang ZX, Zhang WK, Zhang HJ, Xu JK
Journal of Asian natural products research 2022 Jan;24(1):76-87
Journal of Asian natural products research 2022 Jan;24(1):76-87
Isolation and characterization of secondary metabolites from the leaves of Sauropus spatulifolius Beille and their potential biological assays.
Li M, Cui Y, Zhu M, Huang X, Rehman FU, Wang J, Zhang L, Liu T, Liu J, Lu J, Jiang X, Zhang J
Fitoterapia 2022 Jan;156:105100
Fitoterapia 2022 Jan;156:105100
Endothelial cell metabolic memory causes cardiovascular dysfunction in diabetes.
Yao Y, Song Q, Hu C, Da X, Yu Y, He Z, Xu C, Chen Q, Wang QK
Cardiovascular research 2022 Jan 7;118(1):196-211
Cardiovascular research 2022 Jan 7;118(1):196-211
N6-Methyladenosine Modification of CDH1 mRNA Promotes PM2.5-Induced Pulmonary Fibrosis via Mediating Epithelial Mesenchymal Transition.
Ning J, Du H, Zhang Y, Liu Q, Jiang T, Pang Y, Tian X, Yan L, Niu Y, Zhang R
Toxicological sciences : an official journal of the Society of Toxicology 2022 Jan 24;185(2):143-157
Toxicological sciences : an official journal of the Society of Toxicology 2022 Jan 24;185(2):143-157
New IMB16-4 Nanoparticles Improved Oral Bioavailability and Enhanced Anti-Hepatic Fibrosis on Rats.
Niu X, Wang X, Niu B, Wang Y, He H, Li G
Pharmaceuticals (Basel, Switzerland) 2022 Jan 11;15(1)
Pharmaceuticals (Basel, Switzerland) 2022 Jan 11;15(1)
Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.
Xie L, Wang T, Lin S, Lu Z, Wang Y, Shen Z, Cheng Y, Shen A, Peng J, Chu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112607
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112607
One-Step Synthesis of Multifunctional Chitosan Hydrogel for Full-Thickness Wound Closure and Healing.
Guo S, Yao M, Zhang D, He Y, Chang R, Ren Y, Guan F
Advanced healthcare materials 2022 Feb;11(4):e2101808
Advanced healthcare materials 2022 Feb;11(4):e2101808
Remodeling Chondroitin-6-Sulfate-Mediated Immune Exclusion Enhances Anti-PD-1 Response in Colorectal Cancer with Microsatellite Stability.
Wu Q, Huang Q, Jiang Y, Sun F, Liang B, Wang J, Hu X, Sun M, Ma Z, Shi Y, Liang Y, Tan Y, Zeng D, Yao F, Xu X, Yao Z, Li S, Rong X, Huang N, Sun L, Liao W, Shi M
Cancer immunology research 2022 Feb;10(2):182-199
Cancer immunology research 2022 Feb;10(2):182-199
TiO(2) nanosheets promote the transformation of vascular smooth muscle cells into foam cells in vitro and in vivo through the up-regulation of nuclear factor kappa B subunit 2.
Li S, Yan D, Huang C, Yang F, Cao Y
Journal of hazardous materials 2022 Feb 15;424(Pt D):127704
Journal of hazardous materials 2022 Feb 15;424(Pt D):127704
Necroptosis in pulmonary macrophages promotes silica-induced inflammation and interstitial fibrosis in mice.
Tao H, Zhao H, Ge D, Liao J, Shao L, Mo A, Hu L, Xu K, Wu J, Mu M, Li B, Tao X, Wang J
Toxicology letters 2022 Feb 1;355:150-159
Toxicology letters 2022 Feb 1;355:150-159
IL13 and periostin in active fibrogenic areas of the extrahepatic bile ducts in biliary atresia patients.
Sengoku Y, Higashi M, Nagayabu K, Takayama S, Fumino S, Aoi S, Furukawa T, Tajiri T
Pediatric surgery international 2022 Dec;38(12):1847-1853
Pediatric surgery international 2022 Dec;38(12):1847-1853
A comprehensive analysis on the relationship between BDE-209 exposure and erectile dysfunction.
Zhou X, Song L, Cong R, Luan J, Zhou X, Wang Y, Yao L, Zhang X, Ren X, Zhang T, Yu M, Song N
Chemosphere 2022 Dec;308(Pt 3):136486
Chemosphere 2022 Dec;308(Pt 3):136486
Branched-chain amino acid transaminase 1 inhibition attenuates childhood asthma in mice by effecting airway remodeling and autophagy.
Li J, Chen M, Lu L, Wang J, Tan L
Respiratory physiology & neurobiology 2022 Dec;306:103961
Respiratory physiology & neurobiology 2022 Dec;306:103961
Poly I:C Exacerbates Airway Inflammation and Remodeling in Cigarette Smoke-Exposed Mice.
Mei X, Lu R, Cui L, Tian Y, Zhao P, Li J
Lung 2022 Dec;200(6):677-686
Lung 2022 Dec;200(6):677-686
Multifunctional Silk Fibroin Methacryloyl Microneedle for Diabetic Wound Healing.
Guan G, Zhang Q, Jiang Z, Liu J, Wan J, Jin P, Lv Q
Small (Weinheim an der Bergstrasse, Germany) 2022 Dec;18(51):e2203064
Small (Weinheim an der Bergstrasse, Germany) 2022 Dec;18(51):e2203064
Deletion of SIRT6 in vascular smooth muscle cells facilitates vascular calcification via suppression of DNA damage repair.
Wang S, Li L, Liang Q, Ye Y, Lan Z, Dong Q, Chen A, Fu M, Li Y, Liu X, Ou JS, Lu L, Yan J
Journal of molecular and cellular cardiology 2022 Dec;173:154-168
Journal of molecular and cellular cardiology 2022 Dec;173:154-168
IL-8 exacerbates CCl(4)-induced liver fibrosis in human IL-8-expressing mice via the PI3K/Akt/HIF-1α pathway.
Ma Y, Bao Y, Wu L, Ke Y, Tan L, Ren H, Song J, Zhang Q, Jin Y
Molecular immunology 2022 Dec;152:111-122
Molecular immunology 2022 Dec;152:111-122
PVT1/miR-145-5p/HK2 modulates vascular smooth muscle cells phenotype switch via glycolysis: The new perspective on the spiral artery remodeling.
Wu M, Liu W, Huang H, Chen Z, Chen Y, Zhong Y, Jin Z, Liu X, Zou L
Placenta 2022 Dec;130:25-33
Placenta 2022 Dec;130:25-33
Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice.
Lian N, Jin H, Zhu W, Zhang C, Qi Y, Jiang M, Mao J, Lu X, Zhao F, Xi B, Qi X, Li Y
Acta histochemica 2022 Dec;124(8):151961
Acta histochemica 2022 Dec;124(8):151961
Bempedoic acid, an ATP citrate lyase inhibitor, reduces intimal hyperplasia via activation of AMPKα signaling pathway.
Liu W, Liu M, Xiong H, Xia L, Yang Q, Chen M, Cai Y, Li S
International immunopharmacology 2022 Dec;113(Pt A):109392
International immunopharmacology 2022 Dec;113(Pt A):109392
A multifunctional black phosphorus-based adhesive patch intrinsically induces partial EMT for effective burn wound healing.
Wang X, Tang X, Li N, Sun Y, Yu R, Zhang J, Li D, Yang B, Sun H
Biomaterials science 2022 Dec 20;11(1):235-247
Biomaterials science 2022 Dec 20;11(1):235-247
The Influence of Novel, Biocompatible, and Bioresorbable Poly(3-hydroxyoctanoate) Dressings on Wound Healing in Mice.
Seta M, Haraźna K, Kasarełło K, Solarz-Keller D, Cudnoch-Jędrzejewska A, Witko T, Rajfur Z, Guzik M
International journal of molecular sciences 2022 Dec 18;23(24)
International journal of molecular sciences 2022 Dec 18;23(24)
Overexpressed DDX3x promotes abdominal aortic aneurysm formation and activates AKT in ApoE knockout mice.
Zhou Y, Chai H, Hu Y, Liu R, Jiang H, Fan R, Chen W, Chen X, Huang F
Biochemical and biophysical research communications 2022 Dec 17;634:138-144
Biochemical and biophysical research communications 2022 Dec 17;634:138-144
Insights into the mechanism underlying crystalline silica-induced pulmonary fibrosis via transcriptome-wide m(6)A methylation profile.
Zhang Y, Gu P, Xie Y, Fan L, You X, Yang S, Yao Y, Chen W, Ma J
Ecotoxicology and environmental safety 2022 Dec 1;247:114215
Ecotoxicology and environmental safety 2022 Dec 1;247:114215
Development of a human iPSC line (SMBCi017-A) from a healthy donor.
Han Z, Wang J, Luan J, Cui Y, Han J
Stem cell research 2022 Aug;63:102852
Stem cell research 2022 Aug;63:102852
Use of wogonin as a cooperative drug with praziquantel to better combat schistosomiasis.
Pekkle Lam HY, Hung MY, Cheng PC, Peng SY
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2022 Aug;55(4):757-765
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2022 Aug;55(4):757-765
Long noncoding RNA GAS5 inhibits LX-2 cells activation by suppressing NF-κB signalling through regulation of the miR-433-3p/TLR10 axis.
Su SB, Tao L, Liang XL, Chen W
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Aug;54(8):1066-1075
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2022 Aug;54(8):1066-1075
Riboflavin deficiency leads to irreversible cellular changes in the RPE and disrupts retinal function through alterations in cellular metabolic homeostasis.
Sinha T, Ikelle L, Makia MS, Crane R, Zhao X, Kakakhel M, Al-Ubaidi MR, Naash MI
Redox biology 2022 Aug;54:102375
Redox biology 2022 Aug;54:102375
Corn oligopeptides inhibit Akt/NF-κB signaling pathway and inflammatory factors to ameliorate CCl(4) -induced hepatic fibrosis in mice.
Feng XW, Cheng QL, Fang L, Liu WY, Liu LW, Sun CQ, Lu ZH, Li GM, Gu RZ
Journal of food biochemistry 2022 Aug;46(8):e14162
Journal of food biochemistry 2022 Aug;46(8):e14162
Construction and identification of an immortalized rat intestinal smooth muscle cell line.
Chen H, Li X, Gao L, Zhang D, Han T
Neurogastroenterology and motility 2022 Aug;34(8):e14359
Neurogastroenterology and motility 2022 Aug;34(8):e14359
Curcumin attenuates vascular calcification via the exosomal miR-92b-3p/KLF4 axis.
Chen C, Li Y, Lu H, Liu K, Jiang W, Zhang Z, Qin X
Experimental biology and medicine (Maywood, N.J.) 2022 Aug;247(16):1420-1432
Experimental biology and medicine (Maywood, N.J.) 2022 Aug;247(16):1420-1432
FXR deficiency in hepatocytes disrupts the bile acid homeostasis and inhibits autophagy to promote liver injury in Schistosoma japonicum-infected mice.
Zhang B, Li J, Zong X, Wang J, Xin L, Song H, Zhang W, Koda S, Hua H, Zhang B, Yu Q, Zheng KY, Yan C
PLoS neglected tropical diseases 2022 Aug;16(8):e0010651
PLoS neglected tropical diseases 2022 Aug;16(8):e0010651
LncRNA SNHG11 promotes the malignant transformation of human bronchial epithelial cells induced by beryllium sulfate.
Deng W, Sun Z, Chen S, Li G, Liu X, Huang L, Zhang Z
Toxicology research 2022 Aug;11(4):605-615
Toxicology research 2022 Aug;11(4):605-615
Morroniside, a novel GATA3 binding molecule, inhibits hepatic stellate cells activation by enhancing lysosomal acid lipase expression.
An L, Zhang M, Lin Y, Jiang T, Xu K, Xiao S, Cai L, Kwan HY, Liu Z, Su T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154199
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154199
Circ_0047339 promotes the activation of fibroblasts and affects the development of urethral stricture by targeting the miR-4691-5p/TSP-1 axis.
Ding K, Li D, Zhang R, Zuo M
Scientific reports 2022 Aug 30;12(1):14746
Scientific reports 2022 Aug 30;12(1):14746
Integrated single-cell transcriptomics and proteomics reveal cellular-specific responses and microenvironment remodeling in aristolochic acid nephropathy.
Chen J, Luo P, Wang C, Yang C, Bai Y, He X, Zhang Q, Zhang J, Yang J, Wang S, Wang J
JCI insight 2022 Aug 22;7(16)
JCI insight 2022 Aug 22;7(16)
Krill Oil Turns Off TGF-β1 Profibrotic Signaling in the Prevention of Diabetic Nephropathy.
Sun X, Yang Y, Sun X, Meng H, Hao W, Yin J, Ma F, Guo X, Du L, Sun L, Wu H
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9865-9876
Journal of agricultural and food chemistry 2022 Aug 17;70(32):9865-9876
ZC3H4 regulates infiltrating monocytes, attenuating pulmonary fibrosis through IL-10.
Liu Y, Zhang X, Wang J, Yang F, Luo W, Huang J, Chen M, Wang S, Li C, Zhang W, Chao J
Respiratory research 2022 Aug 12;23(1):204
Respiratory research 2022 Aug 12;23(1):204
Antifibrotic and anthelminthic effect of casticin on Schistosoma mansoni-infected BALB/c mice.
Lam HYP, Liang TR, Lan YC, Chang KC, Cheng PC, Peng SY
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2022 Apr;55(2):314-322
Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi 2022 Apr;55(2):314-322
Resolution of systemic complications in Schistosoma mansoni-infected mice by concomitant treatment with praziquantel and Schisandrin B.
Lam HYP, Cheng PC, Peng SY
International journal for parasitology 2022 Apr;52(5):275-284
International journal for parasitology 2022 Apr;52(5):275-284
Botox-A improve the thyroid-associated ophthalmopathy (TAO) orbital fibroblast activation through inhibiting the TGF-β/Smad signaling.
Qi X, Luo B, Deng M, Cao J, Hou S, Xie Z, Tong B, Xiong W
Experimental eye research 2022 Apr;217:108971
Experimental eye research 2022 Apr;217:108971
Pharmacological targeting macrophage phenotype via gut-kidney axis ameliorates renal fibrosis in mice.
Xie Y, Hu X, Li S, Qiu Y, Cao R, Xu C, Lu C, Wang Z, Yang J
Pharmacological research 2022 Apr;178:106161
Pharmacological research 2022 Apr;178:106161
Guizhi Fuling pill attenuates liver fibrosis in vitro and in vivo via inhibiting TGF-β1/Smad2/3 and activating IFN-γ/Smad7 signaling pathways.
Liu Z, Xu B, Ding Y, Ding X, Yang Z
Bioengineered 2022 Apr;13(4):9357-9368
Bioengineered 2022 Apr;13(4):9357-9368
HPV(+) HNSCC-derived exosomal miR-9-5p inhibits TGF-β signaling-mediated fibroblast phenotypic transformation through NOX4.
Wang B, Zhang S, Tong F, Wang Y, Wei L
Cancer science 2022 Apr;113(4):1475-1487
Cancer science 2022 Apr;113(4):1475-1487
Isoandrographolide inhibits NLRP3 inflammasome activation and attenuates silicosis in mice.
Song Z, Wang L, Cao Y, Liu Z, Zhang M, Zhang Z, Jiang S, Fan R, Hao T, Yang R, Wang B, Guan Z, Zhu L, Liu Z, Zhang S, Zhao L, Xu Z, Xu H, Dai G
International immunopharmacology 2022 Apr;105:108539
International immunopharmacology 2022 Apr;105:108539
Mechanosensitive Piezo1 channels mediate renal fibrosis.
Zhao X, Kong Y, Liang B, Xu J, Lin Y, Zhou N, Li J, Jiang B, Cheng J, Li C, Wang W
JCI insight 2022 Apr 8;7(7)
JCI insight 2022 Apr 8;7(7)
PEDF is an antifibrosis factor that inhibits the activation of fibroblasts in a bleomycin-induced pulmonary fibrosis rat model.
Qin X, Jia C, Liang J, Chen J, Liu X, Chao Z, Qin H, Yuan Y, Liu Z, Zhang Z, Dong H, Zhang H
Respiratory research 2022 Apr 22;23(1):100
Respiratory research 2022 Apr 22;23(1):100
TRPM2 Promotes Atherosclerotic Progression in a Mouse Model of Atherosclerosis.
Zhang Y, Ying F, Tian X, Lei Z, Li X, Lo CY, Li J, Jiang L, Yao X
Cells 2022 Apr 22;11(9)
Cells 2022 Apr 22;11(9)
MED12 Regulates Smooth Muscle Cell Functions and Participates in the Development of Aortic Dissection.
Zhou Y, Zha L, Wu J, Wang M, Zhou M, Wu G, Cheng X, Huang Z, Xie Q, Tu X
Genes 2022 Apr 14;13(4)
Genes 2022 Apr 14;13(4)
BRCC36 prevents vascular calcification in chronic kidney disease through the β-catenin signalling pathway.
Xie C, Chen C, Wu L, Xiong Y, Xing C, Mao H
Experimental cell research 2022 Apr 1;413(1):113051
Experimental cell research 2022 Apr 1;413(1):113051
Effect of Microgroove Structure in PDMS-Based Silicone Implants on Biocompatibility.
Chen Y, Zhou X, Huang S, Lan Y, Yan R, Shi X, Li X, Zhang Y, Lei Z, Fan D
Frontiers in bioengineering and biotechnology 2021;9:793778
Frontiers in bioengineering and biotechnology 2021;9:793778
Osteopontin N-Terminal Function in an Abdominal Aortic Aneurysm From Apolipoprotein E-Deficient Mice.
Liu H, Zhang Y, Song W, Sun Y, Jiang Y
Frontiers in cell and developmental biology 2021;9:681790
Frontiers in cell and developmental biology 2021;9:681790
Aberrantly Expressed Galectin-9 Is Involved in the Immunopathogenesis of Anti-MDA5-Positive Dermatomyositis-Associated Interstitial Lung Disease.
Liang L, Zhang YM, Shen YW, Song AP, Li WL, Ye LF, Lu X, Wang GC, Peng QL
Frontiers in cell and developmental biology 2021;9:628128
Frontiers in cell and developmental biology 2021;9:628128
JMJD1A/NR4A1 Signaling Regulates the Procession of Renal Tubular Epithelial Interstitial Fibrosis Induced by AGEs in HK-2.
Wang S, Zuo A, Jiang W, Xie J, Lin H, Sun W, Zhao M, Xia J, Shao J, Zhao X, Liang D, Yang A, Sun J, Wang M
Frontiers in medicine 2021;8:807694
Frontiers in medicine 2021;8:807694
STAT3 and IL-6 Contribute to Corticosteroid Resistance in an OVA and Ozone-induced Asthma Model with Neutrophil Infiltration.
Xue Y, Zhou Y, Bao W, Fu Q, Hao H, Han L, Zhang X, Tian X, Zhang M
Frontiers in molecular biosciences 2021;8:717962
Frontiers in molecular biosciences 2021;8:717962
Circulating Soluble Suppression of Tumorigenicity 2 Predicts Recurrence After Radiofrequency Ablation of Persistent Atrial Fibrillation.
Tan R, Yu H, Han X, Liu Y, Yang X, Xia YL, Yin X
Frontiers in cardiovascular medicine 2021;8:653312
Frontiers in cardiovascular medicine 2021;8:653312
Exosomes Containing LINC00636 Inhibit MAPK1 through the miR-450a-2-3p Overexpression in Human Pericardial Fluid and Improve Cardiac Fibrosis in Patients with Atrial Fibrillation.
Liu L, Luo F, Lei K
Mediators of inflammation 2021;2021:9960241
Mediators of inflammation 2021;2021:9960241
Nobiletin Attenuates Pathological Cardiac Remodeling after Myocardial Infarction via Activating PPARγ and PGC1α.
Zhou Y, Yin T, Shi M, Chen M, Wu X, Wang K, Cheang I, Li Y, Shang H, Zhang H, Li X
PPAR research 2021;2021:9947656
PPAR research 2021;2021:9947656
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
Network Pharmacology-Based Mechanistic Investigation of Jinshui Huanxian Formula Acting on Idiopathic Pulmonary Fibrosis.
Liu T, Xu P, Qi S, Ke S, Hu Q, Zhao P, Li J
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8634705
Evidence-based complementary and alternative medicine : eCAM 2021;2021:8634705
PP2 Ameliorates Renal Fibrosis by Regulating the NF-κB/COX-2 and PPARγ/UCP2 Pathway in Diabetic Mice.
Wei J, Deng X, Li Y, Li R, Yang Z, Li X, Song S, Shi Y, Duan H, Wu H
Oxidative medicine and cellular longevity 2021;2021:7394344
Oxidative medicine and cellular longevity 2021;2021:7394344
Ginkgo Biloba Extract EGB761 Ameliorates the Extracellular Matrix Accumulation and Mesenchymal Transformation of Renal Tubules in Diabetic Kidney Disease by Inhibiting Endoplasmic Reticulum Stress.
Han J, Pang X, Shi X, Zhang Y, Peng Z, Xing Y
BioMed research international 2021;2021:6657206
BioMed research international 2021;2021:6657206
Osthole Attenuates Bleomycin-Induced Pulmonary Fibrosis by Modulating NADPH Oxidase 4-Derived Oxidative Stress in Mice.
Fang L, Wang W, Chen J, Zuo A, Gao H, Yan T, Wang P, Lu Y, Lv R, Xu F, Chen Y, Lyu L
Oxidative medicine and cellular longevity 2021;2021:3309944
Oxidative medicine and cellular longevity 2021;2021:3309944
Puerarin Alleviates UUO-Induced Inflammation and Fibrosis by Regulating the NF-κB P65/STAT3 and TGFβ1/Smads Signaling Pathways.
Wang J, Ge S, Wang Y, Liu Y, Qiu L, Li J, Huang X, Sun L
Drug design, development and therapy 2021;15:3697-3708
Drug design, development and therapy 2021;15:3697-3708
Wogonin Alleviates Kidney Tubular Epithelial Injury in Diabetic Nephropathy by Inhibiting PI3K/Akt/NF-κB Signaling Pathways.
Lei L, Zhao J, Liu XQ, Chen J, Qi XM, Xia LL, Wu YG
Drug design, development and therapy 2021;15:3131-3150
Drug design, development and therapy 2021;15:3131-3150
Fasudil Dichloroacetate Alleviates SU5416/Hypoxia-Induced Pulmonary Arterial Hypertension by Ameliorating Dysfunction of Pulmonary Arterial Smooth Muscle Cells.
Liu P, Huang W, Ding Y, Wu J, Liang Z, Huang Z, Xie W, Kong H
Drug design, development and therapy 2021;15:1653-1666
Drug design, development and therapy 2021;15:1653-1666
Tongluo Yishen Decoction Ameliorates Renal Fibrosis via Regulating Mitochondrial Dysfunction Induced by Oxidative Stress in Unilateral Ureteral Obstruction Rats.
Jia Q, Han L, Zhang X, Yang W, Gao Y, Shen Y, Li B, Wang S, Qin M, Lowe S, Qin J, Hao G
Frontiers in pharmacology 2021;12:762756
Frontiers in pharmacology 2021;12:762756
β2-Adrenergic Receptor Enhances the Alternatively Activated Macrophages and Promotes Biliary Injuries Caused by Helminth Infection.
Koda S, Zhang B, Zhou QY, Xu N, Li J, Liu JX, Liu M, Lv ZY, Wang JL, Shi Y, Gao S, Yu Q, Li XY, Xu YH, Chen JX, Tekengne BOT, Adzika GK, Tang RX, Sun H, Zheng KY, Yan C
Frontiers in immunology 2021;12:754208
Frontiers in immunology 2021;12:754208
Identification of a Novel Gene Correlated With Vascular Smooth Muscle Cells Proliferation and Migration in Chronic Thromboembolic Pulmonary Hypertension.
Wang F, Sun C, Lv X, Sun M, Si C, Zhen Y, Guo J, Sun W, Ye Z, Wen J, Liu P
Frontiers in physiology 2021;12:744219
Frontiers in physiology 2021;12:744219
Transcriptome-Based Network Analysis Reveals Hirudin Potentiates Anti-Renal Fibrosis Efficacy in UUO Rats.
Yu HX, Lin W, Yang K, Wei LJ, Chen JL, Liu XY, Zhong K, Chen X, Pei M, Yang HT
Frontiers in pharmacology 2021;12:741801
Frontiers in pharmacology 2021;12:741801
Icariin Ameliorates Diabetic Renal Tubulointerstitial Fibrosis by Restoring Autophagy via Regulation of the miR-192-5p/GLP-1R Pathway.
Jia Z, Wang K, Zhang Y, Duan Y, Xiao K, Liu S, Ding X
Frontiers in pharmacology 2021;12:720387
Frontiers in pharmacology 2021;12:720387
Azithromycin Attenuates Bleomycin-Induced Pulmonary Fibrosis Partly by Inhibiting the Expression of LOX and LOXL-2.
Tong X, Zhang S, Wang D, Zhang L, Huang J, Zhang T, Fan H
Frontiers in pharmacology 2021;12:709819
Frontiers in pharmacology 2021;12:709819
Comprehensive Bioinformatics Analysis Identifies POLR2I as a Key Gene in the Pathogenesis of Hypertensive Nephropathy.
You S, Xu J, Wu B, Wu S, Zhang Y, Sun Y, Zhang N
Frontiers in genetics 2021;12:698570
Frontiers in genetics 2021;12:698570
Exploration of the Modulatory Property Mechanism of ELeng Capsule in the Treatment of Endometriosis Using Transcriptomics Combined With Systems Network Pharmacology.
Zheng W, Wang J, Wu J, Wang T, Huang Y, Liang X, Cao L
Frontiers in pharmacology 2021;12:674874
Frontiers in pharmacology 2021;12:674874
ShenLian Extract Enhances TGF-β Functions in the Macrophage-SMC Unit and Stabilizes Atherosclerotic Plaques.
Liu L, Li Q, Yin J, Zhao Z, Sun L, Ran Q, Du X, Wang Y, Li Y, Yang Q, Chen Y, Weng X, Cai W, Zhu X
Frontiers in pharmacology 2021;12:669730
Frontiers in pharmacology 2021;12:669730
Pseudoginsenoside F11 Enhances the Viability of Random-Pattern Skin Flaps by Promoting TFEB Nuclear Translocation Through AMPK-mTOR Signal Pathway.
Zhou F, Zhang X, Jiang L, Li S, Chen Y, Wu J
Frontiers in pharmacology 2021;12:667524
Frontiers in pharmacology 2021;12:667524
iTRAQ-Based Proteomics Reveals Gu-Ben-Fang-Xiao Decoction Alleviates Airway Remodeling via Reducing Extracellular Matrix Deposition in a Murine Model of Chronic Remission Asthma.
Xing Q, You Y, Zhao X, Ji J, Yan H, Dong Y, Ren L, Ding Y, Hou S
Frontiers in pharmacology 2021;12:588588
Frontiers in pharmacology 2021;12:588588
Exogenous H(2) S prevents the nuclear translocation of PDC-E1 and inhibits vascular smooth muscle cell proliferation in the diabetic state.
Zhang L, Jiang X, Liu N, Li M, Kang J, Chen L, Tang J, Dong S, Lu F, Zhang W
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Journal of cellular and molecular medicine 2021 Sep;25(17):8201-8214
Interferon-induced protein 16 expression in colorectal cancer and its correlation with proliferation and immune signature markers.
Zou Y, Zhang J, Zhang L, Yan X
Oncology letters 2021 Sep;22(3):687
Oncology letters 2021 Sep;22(3):687
Presegetane diterpenoids from Euphorbia sieboldiana as a new type of anti-liver fibrosis agents that inhibit TGF-β/Smad signaling pathway.
Li S, Gan L, Tian YJ, Tian Y, Fan RZ, Huang D, Yuan FY, Zhang X, Lin Y, Zhu QF, Tang GH, Yan XL, Yin S
Bioorganic chemistry 2021 Sep;114:105222
Bioorganic chemistry 2021 Sep;114:105222
Metformin attenuates vascular pathology by increasing expression of insulin-degrading enzyme in a mixed model of cerebral amyloid angiopathy and type 2 diabetes mellitus.
Inoue Y, Masuda T, Misumi Y, Ando Y, Ueda M
Neuroscience letters 2021 Sep 25;762:136136
Neuroscience letters 2021 Sep 25;762:136136
MiR-200c-3p promotes ox-LDL-induced endothelial to mesenchymal transition in human umbilical vein endothelial cells through SMAD7/YAP pathway.
Mao Y, Jiang L
The journal of physiological sciences : JPS 2021 Sep 15;71(1):30
The journal of physiological sciences : JPS 2021 Sep 15;71(1):30
Effect of different exercise training intensities on age-related cardiac damage in male mice.
Pei Z, Yang C, Guo Y, Dong M, Wang F
Aging 2021 Sep 14;13(17):21700-21711
Aging 2021 Sep 14;13(17):21700-21711
The promoting role of Cx43 on the proliferation and migration of arterial smooth muscle cells for angiotensin II-dependent hypertension.
Gao RJ, Zhang AM, Jia QH, Dang ZT, Tian T, Zhang JR, Cao N, Tang XC, Ma KT, Li L, Si JQ
Pulmonary pharmacology & therapeutics 2021 Oct;70:102072
Pulmonary pharmacology & therapeutics 2021 Oct;70:102072
Heat-killed Propionibacterium acnes augment the protective effect of 28-kDa glutathione S-transferases antigen against Schistosoma mansoni infection.
Lam HYP, Yang TH, Liang TR, Cheng PC, Chang KC, Peng SY
Acta tropica 2021 Oct;222:106033
Acta tropica 2021 Oct;222:106033
Potential Vasculoprotective Effects of Blackcurrant (Ribes nigrum) Extract in Diabetic KK-A(y) Mice.
Horie K, Maeda H, Nanashima N, Oey I
Molecules (Basel, Switzerland) 2021 Oct 26;26(21)
Molecules (Basel, Switzerland) 2021 Oct 26;26(21)
Structure-Guided Design of a Small-Molecule Activator of Sirtuin-3 that Modulates Autophagy in Triple Negative Breast Cancer.
Zhang J, Zou L, Shi D, Liu J, Zhang J, Zhao R, Wang G, Zhang L, Ouyang L, Liu B
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
Journal of medicinal chemistry 2021 Oct 14;64(19):14192-14216
METTL3 improves cardiomyocyte proliferation upon myocardial infarction via upregulating miR-17-3p in a DGCR8-dependent manner.
Zhao K, Yang C, Zhang J, Sun W, Zhou B, Kong X, Shi J
Cell death discovery 2021 Oct 13;7(1):291
Cell death discovery 2021 Oct 13;7(1):291
Methamphetamine mediates apoptosis of vascular smooth muscle cells via the chop-related endoplasmic reticulum stress pathway.
Tan X, Cai D, Chen N, Du S, Qiao D, Yue X, Wang T, Li J, Xie W, Wang H
Toxicology letters 2021 Oct 10;350:98-110
Toxicology letters 2021 Oct 10;350:98-110
Exercise Intervention Mitigates Pathological Liver Changes in NAFLD Zebrafish by Activating SIRT1/AMPK/NRF2 Signaling.
Zou Y, Chen Z, Sun C, Yang D, Zhou Z, Peng X, Zheng L, Tang C
International journal of molecular sciences 2021 Oct 10;22(20)
International journal of molecular sciences 2021 Oct 10;22(20)
Low-intensity pulsed ultrasound prevents prolonged hypoxia-induced cardiac fibrosis through HIF-1α/DNMT3a pathway via a TRAAK-dependent manner.
Zhao K, Weng L, Xu T, Yang C, Zhang J, Ni G, Guo X, Tu J, Zhang D, Sun W, Kong X
Clinical and experimental pharmacology & physiology 2021 Nov;48(11):1500-1514
Clinical and experimental pharmacology & physiology 2021 Nov;48(11):1500-1514
Inhibition of MAD2B alleviates venous neointimal formation by suppressing VSMCs proliferation and migration.
Song AN, Yin XJ, Gao P, Tang H, Meng XF, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2021 Nov;35(11):e21959
Blood glucose control contributes to protein stability of Ski-related novel protein N in a rat model of diabetes.
Liang L, Li S, Liu H, Mao Y, Liu L, Zhang X, Peng W, Xiao Y, Zhang F, Shi M, Wang Y, Guo B
Experimental and therapeutic medicine 2021 Nov;22(5):1341
Experimental and therapeutic medicine 2021 Nov;22(5):1341
Maiwei Yangfei decoction prevents bleomycin-induced pulmonary fibrosis in mice.
Xu Y, Peng W, Han D, Feng F, Wang Z, Gu C, Zhou X, Wu Q
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Experimental and therapeutic medicine 2021 Nov;22(5):1306
Betaine alleviates right ventricular failure via regulation of Rho A/ROCK signaling pathway in rats with pulmonary arterial hypertension.
Lv Y, Ma P, Wang J, Xu Q, Fan J, Yan L, Ma P, Zhou R
European journal of pharmacology 2021 Nov 5;910:174311
European journal of pharmacology 2021 Nov 5;910:174311
MyD88 in Macrophages Enhances Liver Fibrosis by Activation of NLRP3 Inflammasome in HSCs.
Ge S, Yang W, Chen H, Yuan Q, Liu S, Zhao Y, Zhang J
International journal of molecular sciences 2021 Nov 17;22(22)
International journal of molecular sciences 2021 Nov 17;22(22)
SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.
Zhang F, Zhou X, Zou H, Liu L, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Wu Y, Guo B
Experimental cell research 2021 Nov 1;408(1):112856
Experimental cell research 2021 Nov 1;408(1):112856
ZC3H4 mediates silica-induced EndoMT via ER stress and autophagy.
Jiang R, Han L, Gao Q, Chao J
Environmental toxicology and pharmacology 2021 May;84:103605
Environmental toxicology and pharmacology 2021 May;84:103605
Establishment of an iPSC line (CSUXHi004-A) from a patient with Waardenburg syndrome type I caused by a PAX3 splice mutation.
Wen J, He C, Feng Y, Song J, Liu J, Liu X, Mei L, Ling J, Chen H, Liu Y
Stem cell research 2021 May;53:102300
Stem cell research 2021 May;53:102300
Macrophage-derived exosomes mediate silica-induced pulmonary fibrosis by activating fibroblast in an endoplasmic reticulum stress-dependent manner.
Qin X, Lin X, Liu L, Li Y, Li X, Deng Z, Chen H, Chen H, Niu Z, Li Z, Hu Y
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
Journal of cellular and molecular medicine 2021 May;25(9):4466-4477
MiR-155 promotes colitis-associated intestinal fibrosis by targeting HBP1/Wnt/β-catenin signalling pathway.
Li N, Ouyang Y, Xu X, Yuan Z, Liu C, Zhu Z
Journal of cellular and molecular medicine 2021 May;25(10):4765-4775
Journal of cellular and molecular medicine 2021 May;25(10):4765-4775
Splicing factor SRSF6 mediates pleural fibrosis.
Liang LM, Xiong L, Cheng PP, Chen SJ, Feng X, Zhou YY, Niu Q, Wang M, Chen Q, Song LJ, Yu F, He XL, Xiang F, Wang X, Ye H, Ma WL
JCI insight 2021 May 24;6(10)
JCI insight 2021 May 24;6(10)
Controlled release of KGF-2 for regulation of wound healing by KGF-2 complexed with "lotus seedpod surface-like" porous microspheres.
Pan H, Shi C, Yang R, Xi G, Lu C, Yang X, Chen J, Wang X, Chen L, Pan J
Journal of materials chemistry. B 2021 May 19;9(19):4039-4049
Journal of materials chemistry. B 2021 May 19;9(19):4039-4049
Glucagon-like peptide-1 (GLP-1) improved diabetic lung fibrosis via AMPK and microRNA-27a (miR-27a).
Liu J, Li X, Lu S, Zheng X, Zhang X, Zhao W
Annals of translational medicine 2021 Mar;9(6):492
Annals of translational medicine 2021 Mar;9(6):492
KLF4 initiates sustained YAP activation to promote renal fibrosis in mice after ischemia-reperfusion kidney injury.
Xu D, Chen PP, Zheng PQ, Yin F, Cheng Q, Zhou ZL, Xie HY, Li JY, Ni JY, Wang YZ, Chen SJ, Zhou L, Wang XX, Liu J, Zhang W, Lu LM
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
Acta pharmacologica Sinica 2021 Mar;42(3):436-450
Scoparone alleviates Ang II-induced pathological myocardial hypertrophy in mice by inhibiting oxidative stress.
Lyu L, Chen J, Wang W, Yan T, Lin J, Gao H, Li H, Lv R, Xu F, Fang L, Chen Y
Journal of cellular and molecular medicine 2021 Mar;25(6):3136-3148
Journal of cellular and molecular medicine 2021 Mar;25(6):3136-3148
A selective small-molecule inhibitor of c-Met suppresses keloid fibroblast growth in vitro and in a mouse model.
Choi MH, Kim J, Ha JH, Park JU
Scientific reports 2021 Mar 9;11(1):5468
Scientific reports 2021 Mar 9;11(1):5468
Amyloid pathology arrangements in Alzheimer's disease brains modulate in vivo seeding capability.
Duran-Aniotz C, Moreno-Gonzalez I, Gamez N, Perez-Urrutia N, Vegas-Gomez L, Soto C, Morales R
Acta neuropathologica communications 2021 Mar 30;9(1):56
Acta neuropathologica communications 2021 Mar 30;9(1):56
Inhibition of SENP2-mediated Akt deSUMOylation promotes cardiac regeneration via activating Akt pathway.
Chen Y, Xu T, Li M, Li C, Ma Y, Chen G, Sun Y, Zheng H, Wu G, Liao W, Liao Y, Chen Y, Bin J
Clinical science (London, England : 1979) 2021 Mar 26;135(6):811-828
Clinical science (London, England : 1979) 2021 Mar 26;135(6):811-828
Study on the effect of Mongolian medicine Qiwei Qinggan Powder on hepatic fibrosis through JAK2/STAT3 pathway.
Liang J, Yuan H, Xu L, Wang F, Bao X, Yan Y, Wang H, Zhang C, Jin R, Ma L, Zhang J, Huri L, Su X, Xiao R, Ma Y
Bioscience, biotechnology, and biochemistry 2021 Mar 24;85(4):775-785
Bioscience, biotechnology, and biochemistry 2021 Mar 24;85(4):775-785
Anti-Fibrosis Effects of Magnesium Lithospermate B in Experimental Pulmonary Fibrosis: By Inhibiting TGF-βRI/Smad Signaling.
Luo X, Deng Q, Xue Y, Zhang T, Wu Z, Peng H, Xuan L, Pan G
Molecules (Basel, Switzerland) 2021 Mar 19;26(6)
Molecules (Basel, Switzerland) 2021 Mar 19;26(6)
The MIR155 host gene/microRNA-627/HMGB1/NF-κB loop modulates fibroblast proliferation and extracellular matrix deposition.
Li J, Zhang X, Wang T, Li J, Su Q, Zhong C, Chen Z, Liang Y
Life sciences 2021 Mar 15;269:119085
Life sciences 2021 Mar 15;269:119085
Apigenin protects mice against 3,5-diethoxycarbonyl-1,4-dihydrocollidine-induced cholestasis.
Zheng S, Cao P, Yin Z, Wang X, Chen Y, Yu M, Xu B, Liao C, Duan Y, Zhang S, Han J, Yang X
Food & function 2021 Mar 15;12(5):2323-2334
Food & function 2021 Mar 15;12(5):2323-2334
Circular RNA UVRAG Mediated by Alternative Splicing Factor NOVA1 Regulates Adhesion and Migration of Vascular Smooth Muscle Cells.
Liu Z, Lou Y, Cui JC, Chen Y, Liu JT, Yuan Y, Han Y, Huo YL, Qi YX, Jiang ZL, Yao QP
Genes 2021 Mar 14;12(3)
Genes 2021 Mar 14;12(3)
Photobiomodulation therapy promotes the ATP-binding cassette transporter A1-dependent cholesterol efflux in macrophage to ameliorate atherosclerosis.
Yin Q, Chang H, Shen Q, Xing D
Journal of cellular and molecular medicine 2021 Jun;25(11):5238-5249
Journal of cellular and molecular medicine 2021 Jun;25(11):5238-5249
Fructose-1,6-bisphosphatase aggravates oxidative stress-induced apoptosis in asthma by suppressing the Nrf2 pathway.
Hu J, Wang J, Li C, Shang Y
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Journal of cellular and molecular medicine 2021 Jun;25(11):5001-5014
Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo.
Lam HYP, Liang TR, Peng SY
PLoS neglected tropical diseases 2021 Jun;15(6):e0009554
PLoS neglected tropical diseases 2021 Jun;15(6):e0009554
Polysaccharide MCP extracted from Morchella esculenta reduces atherosclerosis in LDLR-deficient mice.
Wang D, Yin Z, Ma L, Han L, Chen Y, Pan W, Gong K, Gao Y, Yang X, Chen Y, Han J, Duan Y
Food & function 2021 Jun 7;12(11):4842-4854
Food & function 2021 Jun 7;12(11):4842-4854
Procyanidin B2 Reduces Vascular Calcification through Inactivation of ERK1/2-RUNX2 Pathway.
Liang Y, Chen G, Zhang F, Yang X, Chen Y, Duan Y, Yu M, Zhang S, Han J
Antioxidants (Basel, Switzerland) 2021 Jun 5;10(6)
Antioxidants (Basel, Switzerland) 2021 Jun 5;10(6)
Interleukin-6 participates in human pancreatic stellate cell activation and collagen I production via TGF-β1/Smad pathway.
Zheng M, Li H, Sun L, Brigstock DR, Gao R
Cytokine 2021 Jul;143:155536
Cytokine 2021 Jul;143:155536
C188-9 reduces TGF-β1-induced fibroblast activation and alleviates ISO-induced cardiac fibrosis in mice.
Liu J, Jin Y, Wang B, Zhang J, Zuo S
FEBS open bio 2021 Jul;11(7):2033-2040
FEBS open bio 2021 Jul;11(7):2033-2040
ets1 associates with KMT5A to participate in high glucose-mediated EndMT via upregulation of PFN2 expression in diabetic nephropathy.
Lu L, Zhong Z, Gu J, Nan K, Zhu M, Miao C
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74
Molecular medicine (Cambridge, Mass.) 2021 Jul 8;27(1):74
Dopamine D1 receptor alleviates doxorubicin-induced cardiac injury by inhibiting NLRP3 inflammasome.
Liu J, Jin Y, Wang B, Wang Y, Zuo S, Zhang J
Biochemical and biophysical research communications 2021 Jul 5;561:7-13
Biochemical and biophysical research communications 2021 Jul 5;561:7-13
Anti-anemia drug FG4592 retards the AKI-to-CKD transition by improving vascular regeneration and antioxidative capability.
Wu M, Chen W, Miao M, Jin Q, Zhang S, Bai M, Fan J, Zhang Y, Zhang A, Jia Z, Huang S
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Clinical science (London, England : 1979) 2021 Jul 30;135(14):1707-1726
Mesenchymal stem cells ameliorate renal fibrosis by galectin-3/Akt/GSK3β/Snail signaling pathway in adenine-induced nephropathy rat.
Tang H, Zhang P, Zeng L, Zhao Y, Xie L, Chen B
Stem cell research & therapy 2021 Jul 16;12(1):409
Stem cell research & therapy 2021 Jul 16;12(1):409
Type 2 Alveolar Epithelial Cells Differentiated from Human Umbilical Cord Mesenchymal Stem Cells Alleviate Mouse Pulmonary Fibrosis Through β-Catenin-Regulated Cell Apoptosis.
Liu J, Peng D, You J, Zhou O, Qiu H, Hao C, Chen H, Fu Z, Zou L
Stem cells and development 2021 Jul 1;30(13):660-670
Stem cells and development 2021 Jul 1;30(13):660-670
Physcion 8-O-β-glucopyranoside ameliorates liver fibrosis through inflammation inhibition by regulating SIRT3-mediated NF-κB P65 nuclear expression.
Chen C, Gu J, Wang J, Wu Y, Yang A, Chen T, Zhou T, Liu Z
International immunopharmacology 2021 Jan;90:107206
International immunopharmacology 2021 Jan;90:107206
Amygdalin inhibits TGFβ1-induced activation of hepatic stellate cells (HSCs) in vitro and CCl(4)-induced hepatic fibrosis in rats in vivo.
Wang R, Zhang D, Tang D, Sun K, Peng J, Zhu W, Yin S, Wu Y
International immunopharmacology 2021 Jan;90:107151
International immunopharmacology 2021 Jan;90:107151
Effect of human umbilical cord-derived mesenchymal stem cells on murine model of bronchiolitis obliterans like injury.
Lin J, Deng H, Zhang Y, Zou L, Fu Z, Dai J
Pediatric pulmonology 2021 Jan;56(1):129-137
Pediatric pulmonology 2021 Jan;56(1):129-137
Tormentic acid inhibits hepatic stellate cells activation via blocking PI3K/Akt/mTOR and NF-κB signalling pathways.
Lin X, Li Y, Zhang X, Wei Y, Wen S, Lu Z, Huang Q, Wei J
Cell biochemistry and function 2021 Jan;39(1):77-87
Cell biochemistry and function 2021 Jan;39(1):77-87
Selective eradication of pluripotent stem cells by inhibiting DHODH activity.
Kondo T
Stem cells (Dayton, Ohio) 2021 Jan;39(1):33-42
Stem cells (Dayton, Ohio) 2021 Jan;39(1):33-42
Endogenous hydrogen sulfide improves vascular remodeling through PPARδ/SOCS3 signaling.
Tian D, Teng X, Jin S, Chen Y, Xue H, Xiao L, Wu Y
Journal of advanced research 2021 Jan;27:115-125
Journal of advanced research 2021 Jan;27:115-125
Comparative cytotoxicity studies of halophenolic disinfection byproducts using human extended pluripotent stem cells.
Liu Y, Zhu D, Zhao Z, Zhou Q, Pan Y, Shi W, Qiu J, Yang Y
Chemosphere 2021 Jan;263:127899
Chemosphere 2021 Jan;263:127899
Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis.
Mo C, Xie S, Liu B, Zhong W, Zeng T, Huang S, Lai Y, Deng G, Zhou C, Yan W, Chen Y, Huang S, Gao L, Lv Z
Cell death & disease 2021 Jan 7;12(1):16
Cell death & disease 2021 Jan 7;12(1):16
Identification of key pathways and hub genes in the myogenic differentiation of pluripotent stem cell: a bioinformatics and experimental study.
Fei W, Liu M, Zhang Y, Cao S, Wang X, Xie B, Wang J
Journal of orthopaedic surgery and research 2021 Jan 4;16(1):4
Journal of orthopaedic surgery and research 2021 Jan 4;16(1):4
MiR-30c-5p regulates adventitial progenitor cells differentiation to vascular smooth muscle cells through targeting OPG.
Zhang Q, Chen T, Zhang Y, Lyu L, Zhang B, Huang C, Zhou X, Wu Y, Li Z
Stem cell research & therapy 2021 Jan 19;12(1):67
Stem cell research & therapy 2021 Jan 19;12(1):67
The zonula occludens protein family regulates the hepatic barrier system in the murine liver.
Itoh M, Terada M, Sugimoto H
Biochimica et biophysica acta. Molecular basis of disease 2021 Jan 1;1867(1):165994
Biochimica et biophysica acta. Molecular basis of disease 2021 Jan 1;1867(1):165994
Up-regulation of FUT8 inhibits TGF-β1-induced activation of hepatic stellate cells during liver fibrogenesis.
Kuang M, Wu H, Hu L, Guo X, He D, Liu B, Chen M, Gu J, Gu J, Zeng X, Ruan Y
Glycoconjugate journal 2021 Feb;38(1):77-87
Glycoconjugate journal 2021 Feb;38(1):77-87
FoxM1 promotes Wnt/β-catenin pathway activation and renal fibrosis via transcriptionally regulating multi-Wnts expressions.
Xie H, Miao N, Xu D, Zhou Z, Ni J, Yin F, Wang Y, Cheng Q, Chen P, Li J, Zheng P, Zhou L, Liu J, Zhang W, Wang X, Lu L
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
Journal of cellular and molecular medicine 2021 Feb;25(4):1958-1971
Involvement of miR-27a-3p in diabetic nephropathy via affecting renal fibrosis, mitochondrial dysfunction, and endoplasmic reticulum stress.
Wu L, Wang Q, Guo F, Ma X, Wang J, Zhao Y, Yan Y, Qin G
Journal of cellular physiology 2021 Feb;236(2):1454-1468
Journal of cellular physiology 2021 Feb;236(2):1454-1468
Keratin 1 attenuates hypoxic pulmonary artery hypertension by suppressing pulmonary artery media smooth muscle expansion.
Zhang L, Zeng XX, Li YM, Chen SK, Tang LY, Wang N, Yang X, Lin MJ
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13558
Acta physiologica (Oxford, England) 2021 Feb;231(2):e13558
BML-111, the lipoxin A4 agonist, modulates VEGF or CoCl2-induced migration, angiogenesis and permeability in tumor-derived endothelial cells.
Lin L, Wang Q, Xu F, Luo X, Xu J, Yan L, Li Q, Hao H
Immunology letters 2021 Feb;230:27-35
Immunology letters 2021 Feb;230:27-35
Fe(3)O(4) magnetic nanoparticles ameliorate albumin-induced tubulointerstitial fibrosis by autophagy related to Rab7.
Liu L, Xu Q, Zhang L, Sun H, Ding F, Li Y, Chen P
Colloids and surfaces. B, Biointerfaces 2021 Feb;198:111470
Colloids and surfaces. B, Biointerfaces 2021 Feb;198:111470
Osteogenic differentiation and calcification of human aortic smooth muscle cells is induced by the RCN2/STAT3/miR-155-5p feedback loop.
Zhao J, Liu Z, Chang Z
Vascular pharmacology 2021 Feb;136:106821
Vascular pharmacology 2021 Feb;136:106821
Preparation of a recombinant collagen-peptide (RHC)-conjugated chitosan thermosensitive hydrogel for wound healing.
Deng A, Yang Y, Du S, Yang X, Pang S, Wang X, Yang S
Materials science & engineering. C, Materials for biological applications 2021 Feb;119:111555
Materials science & engineering. C, Materials for biological applications 2021 Feb;119:111555
Ursodesoxycholic acid alleviates liver fibrosis via proregeneration by activation of the ID1-WNT2/HGF signaling pathway.
Dong X, Luo Y, Lu S, Ma H, Zhang W, Zhu Y, Sun G, Sun X
Clinical and translational medicine 2021 Feb;11(2):e296
Clinical and translational medicine 2021 Feb;11(2):e296
miR-184 targets TP63 to block idiopathic pulmonary fibrosis by inhibiting proliferation and epithelial-mesenchymal transition of airway epithelial cells.
Li J, Pan C, Tang C, Tan W, Zhang W, Guan J
Laboratory investigation; a journal of technical methods and pathology 2021 Feb;101(2):142-154
Laboratory investigation; a journal of technical methods and pathology 2021 Feb;101(2):142-154
Blackcurrant (Ribes nigrum L.) Extract Exerts Potential Vasculoprotective Effects in Ovariectomized Rats, Including Prevention of Elastin Degradation and Pathological Vascular Remodeling.
Horie K, Nanashima N, Maeda H, Tomisawa T, Oey I
Nutrients 2021 Feb 8;13(2)
Nutrients 2021 Feb 8;13(2)
Homocysteine promotes cardiac fibrosis by regulating the Akt/FoxO3 pathway.
Shi Y, Zhao L, Zhang Y, Qin Q, Cong H, Guo Z
Annals of translational medicine 2021 Dec;9(23):1732
Annals of translational medicine 2021 Dec;9(23):1732
NAMPT-mediated NAD(+) biosynthesis suppresses activation of hepatic stellate cells and protects against CCl(4)-induced liver fibrosis in mice.
Xu L, Yang C, Ma J, Zhang X, Wang Q, Xiong X
Human & experimental toxicology 2021 Dec;40(12_suppl):S666-S675
Human & experimental toxicology 2021 Dec;40(12_suppl):S666-S675
Exosomal ANXA2 derived from ovarian cancer cells regulates epithelial-mesenchymal plasticity of human peritoneal mesothelial cells.
Gao L, Nie X, Gou R, Hu Y, Dong H, Li X, Lin B
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Journal of cellular and molecular medicine 2021 Dec;25(23):10916-10929
Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.
Zhao X, Wang J, Tang L, Li P, Ru J, Bai Y
Bioengineered 2021 Dec;12(1):589-600
Bioengineered 2021 Dec;12(1):589-600
Vasoactive intestinal peptide attenuates bleomycin-induced murine pulmonary fibrosis by inhibiting epithelial-mesenchymal transition: Restoring autophagy in alveolar epithelial cells.
Duan JX, Guan XX, Yang HH, Mei WX, Chen P, Tao JH, Li Q, Zhou Y
International immunopharmacology 2021 Dec;101(Pt B):108211
International immunopharmacology 2021 Dec;101(Pt B):108211
MicroRNA-210-5p alleviates cardiac fibrosis via targeting transforming growth factor-beta type I receptor in rats on high sodium chloride (NaCl)-based diet.
Zhao K, Mao Y, Ye X, Ma J, Sun L, Li P, Li Y
European journal of pharmacology 2021 Dec 5;912:174587
European journal of pharmacology 2021 Dec 5;912:174587
Berberine alleviates liver fibrosis through inducing ferrous redox to activate ROS-mediated hepatic stellate cells ferroptosis.
Yi J, Wu S, Tan S, Qin Y, Wang X, Jiang J, Liu H, Wu B
Cell death discovery 2021 Dec 4;7(1):374
Cell death discovery 2021 Dec 4;7(1):374
Inhibition of microRNA-30a alleviates vascular remodeling in pulmonary arterial hypertension.
Ma W, Qiu Z, Bai Z, Dai Y, Li C, Chen X, Song X, Shi D, Zhou Y, Pan Y, Liao Y, Liao M, Zhou Z
Molecular therapy. Nucleic acids 2021 Dec 3;26:678-693
Molecular therapy. Nucleic acids 2021 Dec 3;26:678-693
Pterostilbene Ameliorates Renal Damage in Diabetic Rats by Suppressing Hyperglycemia with Inhibition of Inflammatory and Fibrotic Responses.
Ding RR, Huang GY, Zhang YJ, Sun HL, Liu YM, Xu Z, Li WJ, Li X
Biomedical and environmental sciences : BES 2021 Dec 20;34(12):1015-1019
Biomedical and environmental sciences : BES 2021 Dec 20;34(12):1015-1019
Effects of L-leucine on the properties of spray-dried swellable microparticles with wrinkled surfaces for inhalation therapy of pulmonary fibrosis.
Wang X, Wan W, Lu J, Quan G, Pan X, Liu P
International journal of pharmaceutics 2021 Dec 15;610:121223
International journal of pharmaceutics 2021 Dec 15;610:121223
A suitable silicosis mouse model was constructed by repeated inhalation of silica dust via nose.
Li B, Mu M, Sun Q, Cao H, Liu Q, Liu J, Zhang J, Xu K, Hu D, Tao X, Wang J
Toxicology letters 2021 Dec 15;353:1-12
Toxicology letters 2021 Dec 15;353:1-12
Circular RNA circEsyt2 regulates vascular smooth muscle cell remodeling via splicing regulation.
Gong X, Tian M, Cao N, Yang P, Xu Z, Zheng S, Liao Q, Chen C, Zeng C, Jose PA, Wang DZ, Jian Z, Xiao Y, Jiang DS, Wei X, Zhang B, Wang Y, Chen K, Wu G, Zeng C
The Journal of clinical investigation 2021 Dec 15;131(24)
The Journal of clinical investigation 2021 Dec 15;131(24)
RNO3 QTL regulates vascular structure and arterial stiffness in the spontaneously hypertensive rat.
Morgan EE, Morran MP, Horen NG, Weaver DA, Nestor-Kalinoski AL
Physiological genomics 2021 Dec 1;53(12):534-545
Physiological genomics 2021 Dec 1;53(12):534-545
Histone citrullination by PADI4 is required for HIF-dependent transcriptional responses to hypoxia and tumor vascularization.
Wang Y, Lyu Y, Tu K, Xu Q, Yang Y, Salman S, Le N, Lu H, Chen C, Zhu Y, Wang R, Liu Q, Semenza GL
Science advances 2021 Aug;7(35)
Science advances 2021 Aug;7(35)
BGP-15 Inhibits Hyperglycemia-Aggravated VSMC Calcification Induced by High Phosphate.
Nagy A, Pethő D, Gesztelyi R, Juhász B, Balla G, Szilvássy Z, Balla J, Gáll T
International journal of molecular sciences 2021 Aug 26;22(17)
International journal of molecular sciences 2021 Aug 26;22(17)
PDGF-BB/SA/Dex injectable hydrogels accelerate BMSC-mediated functional full thickness skin wound repair by promoting angiogenesis.
Zhang Z, Li Z, Wang Y, Wang Q, Yao M, Zhao L, Shi J, Guan F, Ma S
Journal of materials chemistry. B 2021 Aug 21;9(31):6176-6189
Journal of materials chemistry. B 2021 Aug 21;9(31):6176-6189
Dysregulations of miR-503-5p and Wnt/β-catenin pathway coordinate in mediating cadmium-induced kidney fibrosis.
Liang L, Huang K, Yuan W, Liu L, Zou F, Wang G
Ecotoxicology and environmental safety 2021 Aug 20;224:112667
Ecotoxicology and environmental safety 2021 Aug 20;224:112667
Generation of an EFNB2-2A-mCherry reporter human embryonic stem cell line using CRISPR/Cas9-mediated site-specific homologous recombination.
Huang Y, Wu H, Han X, Wu J, Yu M, Zhao ZA, Shen Z, Hu S, Lei W
Stem cell research 2021 Apr;52:102241
Stem cell research 2021 Apr;52:102241
mRNA Transcriptome Analysis of Bone in a Mouse Model of Implant-Associated Staphylococcus aureus Osteomyelitis.
Lin Y, Su J, Wang Y, Xu D, Zhang X, Yu B
Infection and immunity 2021 Apr 16;89(5)
Infection and immunity 2021 Apr 16;89(5)
Inhibiting SLC26A4 reverses cardiac hypertrophy in H9C2 cells and in rats.
Tang L, Yu X, Zheng Y, Zhou N
PeerJ 2020;8:e8253
PeerJ 2020;8:e8253
The Effect of Resveratrol and Quercetin on Epithelial-Mesenchymal Transition in Pancreatic Cancer Stem Cell.
Hoca M, Becer E, Kabadayı H, Yücecan S, Vatansever HS
Nutrition and cancer 2020;72(7):1231-1242
Nutrition and cancer 2020;72(7):1231-1242
Glutamate-Cysteine Ligase Catalytic Subunit Attenuated Hepatitis C Virus-Related Liver Fibrosis and Suppressed Endoplasmic Reticulum Stress.
Fu N, Li D, Li W, Zhao W, Zhang S, Liu L, Zhao S, Du J, Kong L, Wang R, Zhang Y, Nan Y
Frontiers in molecular biosciences 2020;7:199
Frontiers in molecular biosciences 2020;7:199
Sodium Tanshinone IIA Sulfonate Attenuates Erectile Dysfunction in Rats with Hyperlipidemia.
Zhong L, Ding W, Zeng Q, He B, Zhang H, Wang L, Fan J, He S, Zhang Y, Wei A
Oxidative medicine and cellular longevity 2020;2020:7286958
Oxidative medicine and cellular longevity 2020;2020:7286958
Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway.
Xia Y, Li J, Chen K, Feng J, Guo C
PPAR research 2020;2020:6694214
PPAR research 2020;2020:6694214
Withaferin A Exerts Preventive Effect on Liver Fibrosis through Oxidative Stress Inhibition in a Sirtuin 3-Dependent Manner.
Gu J, Chen C, Wang J, Chen T, Yao W, Yan T, Liu Z
Oxidative medicine and cellular longevity 2020;2020:2452848
Oxidative medicine and cellular longevity 2020;2020:2452848
Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line.
Sun L, Qu L, Brigstock DR, Li H, Li Y, Gao R
International journal of medical sciences 2020;17(1):137-144
International journal of medical sciences 2020;17(1):137-144
Septin4 Prevents PDGF-BB-induced HAVSMC Phenotypic Transformation, Proliferation and Migration by Promoting SIRT1-STAT3 Deacetylation and Dephosphorylation.
Zhang N, Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y
International journal of biological sciences 2020;16(4):708-718
International journal of biological sciences 2020;16(4):708-718
The role of Stim1 in the progression of lupus nephritis in mice.
Zhang F, Zhou X, Cui D, Zhang W, Lai J, Li X, Ruan Y, Xie Y, Shi M, Xiao Y, Wang Y, Zhou Y, Guo B
International journal of clinical and experimental pathology 2020;13(12):3021-3032
International journal of clinical and experimental pathology 2020;13(12):3021-3032
Inactivation of Pancreatic Stellate Cells by Exendin-4 Inhibits the Migration and Invasion of Pancreatic Cancer Cells.
Yan M, Shen M, Xu L, Huang J, He G, An M, Li X, Gao Z, Meng X
OncoTargets and therapy 2020;13:9455-9463
OncoTargets and therapy 2020;13:9455-9463
High-Intensity Interval Training Attenuates Ketogenic Diet-Induced Liver Fibrosis in Type 2 Diabetic Mice by Ameliorating TGF-β1/Smad Signaling.
Zhang Q, Shen F, Shen W, Xia J, Wang J, Zhao Y, Zhang Z, Sun Y, Qian M, Ding S
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:4209-4219
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:4209-4219
Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha.
Ndibalema AR, Kabuye D, Wen S, Li L, Li X, Fan Q
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Diabetes, metabolic syndrome and obesity : targets and therapy 2020;13:1953-1967
Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis.
Shi J, Xiao P, Liu X, Chen Y, Xu Y, Fan J, Yin Y
Frontiers in physiology 2020;11:669
Frontiers in physiology 2020;11:669
Integrating Network Pharmacology and Experimental Validation to Investigate the Effects and Mechanism of Astragalus Flavonoids Against Hepatic Fibrosis.
An L, Lin Y, Li L, Kong M, Lou Y, Wu J, Liu Z
Frontiers in pharmacology 2020;11:618262
Frontiers in pharmacology 2020;11:618262
Fisetin Alleviated Bleomycin-Induced Pulmonary Fibrosis Partly by Rescuing Alveolar Epithelial Cells From Senescence.
Zhang L, Tong X, Huang J, Wu M, Zhang S, Wang D, Liu S, Fan H
Frontiers in pharmacology 2020;11:553690
Frontiers in pharmacology 2020;11:553690
Hyperoside Attenuates Bleomycin-Induced Pulmonary Fibrosis Development in Mice.
Huang J, Tong X, Zhang L, Zhang Y, Wang L, Wang D, Zhang S, Fan H
Frontiers in pharmacology 2020;11:550955
Frontiers in pharmacology 2020;11:550955
Fibroblast Growth Factor 1 Ameliorates Diabetes-Induced Liver Injury by Reducing Cellular Stress and Restoring Autophagy.
Xu Z, Wu Y, Wang F, Li X, Wang P, Li Y, Wu J, Li Y, Jiang T, Pan X, Zhang X, Xie L, Xiao J, Liu Y
Frontiers in pharmacology 2020;11:52
Frontiers in pharmacology 2020;11:52
Scutellarein inhibits BLM-mediated pulmonary fibrosis by affecting fibroblast differentiation, proliferation, and apoptosis.
Miao K, Pan T, Mou Y, Zhang L, Xiong W, Xu Y, Yu J, Wang Y
Therapeutic advances in chronic disease 2020;11:2040622320940185
Therapeutic advances in chronic disease 2020;11:2040622320940185
GADD45B Promotes Glucose-Induced Renal Tubular Epithelial-Mesenchymal Transition and Apoptosis via the p38 MAPK and JNK Signaling Pathways.
Xue M, Sun H, Xu R, Wang Y, Guo J, Li X, Cheng Y, Xu C, Tang C, Sun B, Chen L
Frontiers in physiology 2020;11:1074
Frontiers in physiology 2020;11:1074
Salvia miltiorrhiza-derived miRNAs suppress vascular remodeling through regulating OTUD7B/KLF4/NMHC IIA axis.
Yang GS, Zheng B, Qin Y, Zhou J, Yang Z, Zhang XH, Zhao HY, Yang HJ, Wen JK
Theranostics 2020;10(17):7787-7811
Theranostics 2020;10(17):7787-7811
Aerosolized Thyroid Hormone Prevents Radiation Induced Lung Fibrosis.
Li L, Nie X, Yi M, Qin W, Li F, Wu B, Yuan X
Frontiers in oncology 2020;10:528686
Frontiers in oncology 2020;10:528686
The F-box protein FBXO11 restrains hepatocellular carcinoma stemness via promotion of ubiquitin-mediated degradation of Snail.
Shao L, Zhang X, Yao Q
FEBS open bio 2020 Sep;10(9):1810-1820
FEBS open bio 2020 Sep;10(9):1810-1820
Abnormal expression of homeobox c6 in the atherosclerotic aorta and its effect on proliferation and migration of rat vascular smooth muscle cells.
Long X, You G, Wu Q, Zhou Y, Yu F, Xiao Y, Deng S, Song F, Huang J, Tian M
Acta biochimica et biophysica Sinica 2020 Sep 8;52(9):935-943
Acta biochimica et biophysica Sinica 2020 Sep 8;52(9):935-943
Inhibition of p66Shc Oxidative Signaling via CA-Induced Upregulation of miR-203a-3p Alleviates Liver Fibrosis Progression.
Wang Z, Zhao Y, Zhao H, Zhou J, Feng D, Tang F, Li Y, Lv L, Chen Z, Ma X, Tian X, Yao J
Molecular therapy. Nucleic acids 2020 Sep 4;21:751-763
Molecular therapy. Nucleic acids 2020 Sep 4;21:751-763
Porphyromonas gingivalis disrupts vascular endothelial homeostasis in a TLR-NF-κB axis dependent manner.
Xie M, Tang Q, Yu S, Sun J, Mei F, Zhao J, Chen L
International journal of oral science 2020 Sep 30;12(1):28
International journal of oral science 2020 Sep 30;12(1):28
Salvianolic acid B and sodium tanshinone II A sulfonate prevent pulmonary fibrosis through anti-inflammatory and anti-fibrotic process.
Jiang L, Wang J, Ju J, Dai J
European journal of pharmacology 2020 Sep 15;883:173352
European journal of pharmacology 2020 Sep 15;883:173352
LncRNA Mical2/miR-203a-3p sponge participates in epithelial-mesenchymal transition by targeting p66Shc in liver fibrosis.
Zhao Y, Wang Z, Zhou J, Feng D, Li Y, Hu Y, Zhang F, Chen Z, Wang G, Ma X, Tian X, Yao J
Toxicology and applied pharmacology 2020 Sep 15;403:115125
Toxicology and applied pharmacology 2020 Sep 15;403:115125
Paired box 9 regulates VSMC phenotypic transformation, proliferation, and migration via sonic hedgehog.
Xu J, Zhang Y, You S, Guo Y, Chen S, Chang Y, Zhang N, Sun Y
Life sciences 2020 Sep 15;257:118053
Life sciences 2020 Sep 15;257:118053
CTRP15 derived from cardiac myocytes attenuates TGFβ1-induced fibrotic response in cardiac fibroblasts.
Zhao Q, Zhang CL, Xiang RL, Wu LL, Li L
Cardiovascular drugs and therapy 2020 Oct;34(5):591-604
Cardiovascular drugs and therapy 2020 Oct;34(5):591-604
Emodin inhibiting neutrophil elastase-induced epithelial-mesenchymal transition through Notch1 signalling in alveolar epithelial cells.
Zhou L, Gao R, Hong H, Li X, Yang J, Shen W, Wang Z, Yang J
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
Journal of cellular and molecular medicine 2020 Oct;24(20):11998-12007
Polydeoxyribonucleotide-delivering therapeutic hydrogel for diabetic wound healing.
Shin DY, Park JU, Choi MH, Kim S, Kim HE, Jeong SH
Scientific reports 2020 Oct 8;10(1):16811
Scientific reports 2020 Oct 8;10(1):16811
Spred2-deficiency enhances the proliferation of lung epithelial cells and alleviates pulmonary fibrosis induced by bleomycin.
Kawara A, Mizuta R, Fujisawa M, Ito T, Li C, Nakamura K, Sun C, Kuwabara M, Kitabatake M, Yoshimura T, Matsukawa A
Scientific reports 2020 Oct 5;10(1):16490
Scientific reports 2020 Oct 5;10(1):16490
IL-32 induces epithelial-mesenchymal transition by triggering endoplasmic reticulum stress in A549 cells.
Gong L, Liu G, Zhu H, Li C, Li P, Liu C, Tang H, Wu K, Wu J, Liu D, Tang X
BMC pulmonary medicine 2020 Oct 23;20(1):278
BMC pulmonary medicine 2020 Oct 23;20(1):278
P38 Inhibition Prevents Herpes Simplex Virus Type 1 (HSV-1) Infection in Cultured Corneal Keratocytes.
Xian-Kui H, Hui-Fang W, Jing-Ran S, Yu-Rong H, Bo-Yu C, Xiu-Jun S
Current eye research 2020 Nov;45(11):1342-1351
Current eye research 2020 Nov;45(11):1342-1351
Inhibition of microRNA-150-5p alleviates cardiac inflammation and fibrosis via targeting Smad7 in high glucose-treated cardiac fibroblasts.
Che H, Wang Y, Li Y, Lv J, Li H, Liu Y, Dong R, Sun Y, Xu X, Zhao J, Wang L
Journal of cellular physiology 2020 Nov;235(11):7769-7779
Journal of cellular physiology 2020 Nov;235(11):7769-7779
Cancer-associated fibroblasts induce epithelial-mesenchymal transition and cisplatin resistance in ovarian cancer via CXCL12/CXCR4 axis.
Zhang F, Cui JY, Gao HF, Yu H, Gao FF, Chen JL, Chen L
Future oncology (London, England) 2020 Nov;16(32):2619-2633
Future oncology (London, England) 2020 Nov;16(32):2619-2633
OXPHOS-dependent metabolic reprogramming prompts metastatic potential of breast cancer cells under osteogenic differentiation.
Hu Y, Xu W, Zeng H, He Z, Lu X, Zuo D, Qin G, Chen W
British journal of cancer 2020 Nov;123(11):1644-1655
British journal of cancer 2020 Nov;123(11):1644-1655
Depleting RhoA/Stress Fiber-Organized Fibronectin Matrices on Tumor Cells Non-Autonomously Aggravates Fibroblast-Driven Tumor Cell Growth.
Huang LT, Tsai CL, Huang SH, Chang MM, Chang WT, Cheng LH, Cheng HC
International journal of molecular sciences 2020 Nov 4;21(21)
International journal of molecular sciences 2020 Nov 4;21(21)
Downregulation of lysyl oxidase in venous malformations: Association with vascular destabilization and sclerotherapy.
Zhu J, Shao M, Guo F, Ren J, Tang Z, Geng J, Xu Z, Jia J, Chen L, Jia Y
The Journal of dermatology 2020 May;47(5):518-526
The Journal of dermatology 2020 May;47(5):518-526
Generation and characterization of a human iPSC line derived from congenital clubfoot amniotic fluid cells.
Wang J, Cui Y, Xing K, Luan J, Han J
Stem cell research 2020 Mar;43:101712
Stem cell research 2020 Mar;43:101712
Upregulation of KSRP by miR-27b attenuates schistosomiasis-induced hepatic fibrosis by targeting TGF-β1.
Wang S, Li M, Zhao X, Wang H, Zhu J, Wang C, Zhou M, Dong H, Zhou R
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4120-4133
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Mar;34(3):4120-4133
TSP-1 as a novel biological marker of tumor vasculature normalization in colon carcinoma induced by Endostar.
Yang W, Li W, Pan F, Yang XY, Zhao X, Qin L, Pan Y
Oncology letters 2020 Mar;19(3):2107-2114
Oncology letters 2020 Mar;19(3):2107-2114
Sirtuin 6 attenuates epithelial-mesenchymal transition by suppressing the TGF-β1/Smad3 pathway and c-Jun in asthma models.
Liu F, Shang YX
International immunopharmacology 2020 Mar 3;82:106333
International immunopharmacology 2020 Mar 3;82:106333
The mechanism and role of intracellular α-ketoglutarate reduction in hepatic stellate cell activation.
Zhao J, Jiang Y, Sun X, Liu X, Liu F, Song M, Zhang L
Bioscience reports 2020 Mar 27;40(3)
Bioscience reports 2020 Mar 27;40(3)
LTBP1 promotes esophageal squamous cell carcinoma progression through epithelial-mesenchymal transition and cancer-associated fibroblasts transformation.
Cai R, Wang P, Zhao X, Lu X, Deng R, Wang X, Su Z, Hong C, Lin J
Journal of translational medicine 2020 Mar 26;18(1):139
Journal of translational medicine 2020 Mar 26;18(1):139
Ophiocordyceps lanpingensis polysaccharides attenuate pulmonary fibrosis in mice.
Zhou S, Zhou Y, Yu J, Du Y, Tan Y, Ke Y, Wang J, Han B, Ge F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110058
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Jun;126:110058
Ubiquitin C-terminal hydrolase L1 (UCHL1) regulates post-myocardial infarction cardiac fibrosis through glucose-regulated protein of 78 kDa (GRP78).
Lei Q, Yi T, Li H, Yan Z, Lv Z, Li G, Wang Y
Scientific reports 2020 Jun 30;10(1):10604
Scientific reports 2020 Jun 30;10(1):10604
MiR-377-3p inhibits atherosclerosis-associated vascular smooth muscle cell proliferation and migration via targeting neuropilin2.
Wang H, Wei Z, Li H, Guan Y, Han Z, Wang H, Liu B
Bioscience reports 2020 Jun 26;40(6)
Bioscience reports 2020 Jun 26;40(6)
Exploring the potential of engineered exosomes as delivery systems for tumor-suppressor microRNA replacement therapy in ovarian cancer.
Kobayashi M, Sawada K, Miyamoto M, Shimizu A, Yamamoto M, Kinose Y, Nakamura K, Kawano M, Kodama M, Hashimoto K, Kimura T
Biochemical and biophysical research communications 2020 Jun 18;527(1):153-161
Biochemical and biophysical research communications 2020 Jun 18;527(1):153-161
LncRNA NNT-AS1 promote glioma cell proliferation and metastases through miR-494-3p/PRMT1 axis.
Zheng D, Chen D, Lin F, Wang X, Lu L, Luo S, Chen J, Xu X
Cell cycle (Georgetown, Tex.) 2020 Jul;19(13):1621-1631
Cell cycle (Georgetown, Tex.) 2020 Jul;19(13):1621-1631
Administration of a mixture of triterpenoids from yeyachun and phenolic acids from danshen ameliorates carbon tetrachloride-induced liver fibrosis in mice by the regulation of intestinal flora.
Tan Y, Li Y, Zhou F, Guo J, Wang T, Shi Y, Yang Y, Lu J, Pei G
Journal of pharmacological sciences 2020 Jul;143(3):165-175
Journal of pharmacological sciences 2020 Jul;143(3):165-175
Elk-1 transcriptionally regulates ZC3H4 expression to promote silica-induced epithelial-mesenchymal transition.
Jiang R, Gao Q, Chen M, Yu T
Laboratory investigation; a journal of technical methods and pathology 2020 Jul;100(7):959-973
Laboratory investigation; a journal of technical methods and pathology 2020 Jul;100(7):959-973
Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement.
Jin Y, Ding L, Ding Z, Fu Y, Song Y, Jing Y, Li Q, Zhang J, Ni Y, Hu Q
Scientific reports 2020 Jul 9;10(1):11269
Scientific reports 2020 Jul 9;10(1):11269
Single-Cell Transcriptome Analysis Reveals Intratumoral Heterogeneity in ccRCC, which Results in Different Clinical Outcomes.
Hu J, Chen Z, Bao L, Zhou L, Hou Y, Liu L, Xiong M, Zhang Y, Wang B, Tao Z, Chen K
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jul 8;28(7):1658-1672
Molecular therapy : the journal of the American Society of Gene Therapy 2020 Jul 8;28(7):1658-1672
Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis.
Chen WC, Chen NJ, Chen HP, Yu WK, Su VY, Chen H, Wu HH, Yang KY
International journal of molecular sciences 2020 Jul 2;21(13)
International journal of molecular sciences 2020 Jul 2;21(13)
TIM-4 interference in Kupffer cells against CCL4-induced liver fibrosis by mediating Akt1/Mitophagy signalling pathway.
Wu H, Chen G, Wang J, Deng M, Yuan F, Gong J
Cell proliferation 2020 Jan;53(1):e12731
Cell proliferation 2020 Jan;53(1):e12731
Subcellular trafficking of tubular MDM2 implicates in acute kidney injury to chronic kidney disease transition during multiple low-dose cisplatin exposure.
Su H, Ye C, Lei CT, Tang H, Zeng JY, Yi F, Zhang C
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1620-1636
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Jan;34(1):1620-1636
Celastrol exerts anti-inflammatory effect in liver fibrosis via activation of AMPK-SIRT3 signalling.
Wang Y, Li C, Gu J, Chen C, Duanmu J, Miao J, Yao W, Tao J, Tu M, Xiong B, Zhao L, Liu Z
Journal of cellular and molecular medicine 2020 Jan;24(1):941-953
Journal of cellular and molecular medicine 2020 Jan;24(1):941-953
Single-cell reconstruction of the adult human heart during heart failure and recovery reveals the cellular landscape underlying cardiac function.
Wang L, Yu P, Zhou B, Song J, Li Z, Zhang M, Guo G, Wang Y, Chen X, Han L, Hu S
Nature cell biology 2020 Jan;22(1):108-119
Nature cell biology 2020 Jan;22(1):108-119
Connexin32 ameliorates renal fibrosis in diabetic mice by promoting K48-linked NADPH oxidase 4 polyubiquitination and degradation.
Chen Z, Sun X, Chen Q, Lan T, Huang K, Xiao H, Lin Z, Yang Y, Liu P, Huang H
British journal of pharmacology 2020 Jan;177(1):145-160
British journal of pharmacology 2020 Jan;177(1):145-160
Long non-coding RNA RNF7 promotes the cardiac fibrosis in rat model via miR-543/THBS1 axis and TGFβ1 activation.
Ouyang F, Liu X, Liu G, Qiu H, He Y, Hu H, Jiang P
Aging 2020 Jan 8;12(1):996-1010
Aging 2020 Jan 8;12(1):996-1010
Bleomycin induces epithelial-to-mesenchymal transition via bFGF/PI3K/ESRP1 signaling in pulmonary fibrosis.
Weng CM, Li Q, Chen KJ, Xu CX, Deng MS, Li T, Zhang DD, Duan ZX, Chen ZQ, Li GH, Chen J, Wang JM
Bioscience reports 2020 Jan 31;40(1)
Bioscience reports 2020 Jan 31;40(1)
Telmisartan inhibits oxalate and calcium oxalate crystal-induced epithelial-mesenchymal transformation via PPAR-γ-AKT/STAT3/p38 MAPK-Snail pathway.
Liu Y, Chen S, Liu J, Jin Y, Yu S, An R
Life sciences 2020 Jan 15;241:117108
Life sciences 2020 Jan 15;241:117108
Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis.
Fu S, Li Y, Wu Y, Yue Y, Yang D
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
The Journal of pharmacy and pharmacology 2020 Feb;72(2):227-235
SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1α.
Zhang W, Dong Z, Xu M, Zhang S, Liu C, Chen S
Molecular metabolism 2020 Feb;32:85-96
Molecular metabolism 2020 Feb;32:85-96
Role of WW domain E3 ubiquitin protein ligase 2 in modulating ubiquitination and Degradation of Septin4 in oxidative stress endothelial injury.
Zhang N, Zhang Y, Wu B, You S, Sun Y
Redox biology 2020 Feb;30:101419
Redox biology 2020 Feb;30:101419
Jiawei Yanghe decoction ameliorates cartilage degradation in vitro and vivo via Wnt/β-catenin signaling pathway.
Xia H, Cao D, Yang F, Yang W, Li W, Liu P, Wang S, Yang F
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109708
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Feb;122:109708
Pluripotent hematopoietic stem cells augment α-adrenergic receptor-mediated contraction of pulmonary artery and contribute to the pathogenesis of pulmonary hypertension.
Hashimoto R, Lanier GM, Dhagia V, Joshi SR, Jordan A, Waddell I, Tuder R, Stenmark KR, Wolin MS, McMurtry IF, Gupte SA
American journal of physiology. Lung cellular and molecular physiology 2020 Feb 1;318(2):L386-L401
American journal of physiology. Lung cellular and molecular physiology 2020 Feb 1;318(2):L386-L401
Establishment of a control induced pluripotent stem cell line SMBCi006-A from a healthy male donor.
Shi L, Cui Y, Zhang G, Zhou X, Luan J, Han J
Stem cell research 2020 Dec;49:102025
Stem cell research 2020 Dec;49:102025
miR-448-3p alleviates diabetic vascular dysfunction by inhibiting endothelial-mesenchymal transition through DPP-4 dysregulation.
Guan GY, Wei N, Song T, Zhao C, Sun Y, Pan RX, Zhang LL, Xu YY, Dai YM, Han H
Journal of cellular physiology 2020 Dec;235(12):10024-10036
Journal of cellular physiology 2020 Dec;235(12):10024-10036
HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications.
Zhao Y, Li M, Yao X, Fei Y, Lin Z, Li Z, Cai K, Zhao Y, Luo Z
Cell reports 2020 Dec 8;33(10):108487
Cell reports 2020 Dec 8;33(10):108487
Extracellular histones stimulate collagen expression in vitro and promote liver fibrogenesis in a mouse model via the TLR4-MyD88 signaling pathway.
Wang Z, Cheng ZX, Abrams ST, Lin ZQ, Yates ED, Yu Q, Yu WP, Chen PS, Toh CH, Wang GZ
World journal of gastroenterology 2020 Dec 21;26(47):7513-7527
World journal of gastroenterology 2020 Dec 21;26(47):7513-7527
β2-microglobulin as a biomarker of pulmonary fibrosis development in COPD patients.
Wu Z, Yan M, Zhang M, Wu N, Ma G, Wang B, Fan Y, Du X, Ding C, Liu Y
Aging 2020 Dec 21;13(1):1251-1263
Aging 2020 Dec 21;13(1):1251-1263
Apremilast interferes with the TGFβ1-induced transition of human skin fibroblasts into profibrotic myofibroblasts: in vitro study.
Cutolo M, Soldano S, Montagna P, Martinelli G, Tardito S, Corallo C, Giordano N, Tavilla P, Cozzani E, Parodi A, Sulli A, Pizzorni C, Patane M, Smith V, Paolino S
Rheumatology (Oxford, England) 2020 Dec 1;59(12):3927-3938
Rheumatology (Oxford, England) 2020 Dec 1;59(12):3927-3938
Silencing of the lncRNA TUG1 attenuates the epithelial-mesenchymal transition of renal tubular epithelial cells by sponging miR-141-3p via regulating β-catenin.
Zhang B, Zhao C, Hou L, Wu Y
American journal of physiology. Renal physiology 2020 Dec 1;319(6):F1125-F1134
American journal of physiology. Renal physiology 2020 Dec 1;319(6):F1125-F1134
LncRNA Gm16410 regulates PM(2.5)-induced lung Endothelial-Mesenchymal Transition via the TGF-β1/Smad3/p-Smad3 pathway.
Ma K, Li C, Xu J, Ren F, Xu X, Liu C, Niu B, Li F
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Ecotoxicology and environmental safety 2020 Dec 1;205:111327
Ammonia exposure causes lung injuries and disturbs pulmonary circadian clock gene network in a pig study.
Wang X, Wang M, Chen S, Wei B, Gao Y, Huang L, Liu C, Huang T, Yu M, Zhao SH, Li X
Ecotoxicology and environmental safety 2020 Dec 1;205:111050
Ecotoxicology and environmental safety 2020 Dec 1;205:111050
Atorvastatin attenuates TGF‑β1‑induced fibrogenesis by inhibiting Smad3 and MAPK signaling in human ventricular fibroblasts.
Du Y, Xiao H, Wan J, Wang X, Li T, Zheng S, Feng J, Ye Q, Li J, Li G, Fan Z
International journal of molecular medicine 2020 Aug;46(2):633-640
International journal of molecular medicine 2020 Aug;46(2):633-640
Maladjustment of β-CGRP/α-CGRP Regulation of AQP5 Promotes Transition of Alveolar Epithelial Cell Apoptosis to Pulmonary Fibrosis.
Lv X, Gao F, Zhang S, Zhang S, Zhou X, Ding F, Wang J, Chen Q, Chen M, Liu Q
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 Aug;40(8):377-388
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2020 Aug;40(8):377-388
WWP2 regulates SIRT1-STAT3 acetylation and phosphorylation involved in hypertensive angiopathy.
Zhang Y, You S, Tian Y, Lu S, Cao L, Sun Y, Zhang N
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Journal of cellular and molecular medicine 2020 Aug;24(16):9041-9054
Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.
Wu L, Mo W, Feng J, Li J, Yu Q, Li S, Zhang J, Chen K, Ji J, Dai W, Wu J, Xu X, Mao Y, Guo C
British journal of pharmacology 2020 Aug;177(16):3760-3777
British journal of pharmacology 2020 Aug;177(16):3760-3777
Icotinib Attenuates Monocrotaline-Induced Pulmonary Hypertension by Preventing Pulmonary Arterial Smooth Muscle Cell Dysfunction.
Peng LY, Yu M, Yang MX, Liu P, Zhou H, Huang W, Kong H, Xie WP
American journal of hypertension 2020 Aug 4;33(8):775-783
American journal of hypertension 2020 Aug 4;33(8):775-783
Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease.
Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, Leng X
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Antioxidants (Basel, Switzerland) 2020 Aug 25;9(9)
Trichostatin A Alleviates Renal Interstitial Fibrosis Through Modulation of the M2 Macrophage Subpopulation.
Tseng WC, Tsai MT, Chen NJ, Tarng DC
International journal of molecular sciences 2020 Aug 19;21(17)
International journal of molecular sciences 2020 Aug 19;21(17)
Regulation of NLRP3 inflammasome by CD38 through cADPR-mediated Ca(2+) release in vascular smooth muscle cells in diabetic mice.
Li JP, Wei W, Li XX, Xu M
Life sciences 2020 Aug 15;255:117758
Life sciences 2020 Aug 15;255:117758
Melatonin alleviates cardiac fibrosis via inhibiting lncRNA MALAT1/miR-141-mediated NLRP3 inflammasome and TGF-β1/Smads signaling in diabetic cardiomyopathy.
Che H, Wang Y, Li H, Li Y, Sahil A, Lv J, Liu Y, Yang Z, Dong R, Xue H, Wang L
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):5282-5298
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 Apr;34(4):5282-5298
Icariside II attenuates eosinophils-induced airway inflammation and remodeling via inactivation of NF-κB and STAT3 in an asthma mouse model.
Tian C, Gao F, Li X, Li Z
Experimental and molecular pathology 2020 Apr;113:104373
Experimental and molecular pathology 2020 Apr;113:104373
Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke.
Zhang Y, Zhang X, Wei Q, Leng S, Li C, Han B, Bai Y, Zhang H, Yao H
Translational stroke research 2020 Apr;11(2):267-287
Translational stroke research 2020 Apr;11(2):267-287
Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro.
He J, Jiang YL, Wang Y, Tian XJ, Sun SR
Chinese medical journal 2020 Apr 5;133(7):800-807
Chinese medical journal 2020 Apr 5;133(7):800-807
The metastatic phenotype shift toward myofibroblast of adipose-derived mesenchymal stem cells promotes ovarian cancer progression.
Tang H, Chu Y, Huang Z, Cai J, Wang Z
Carcinogenesis 2020 Apr 22;41(2):182-193
Carcinogenesis 2020 Apr 22;41(2):182-193
Exosomal miR-125a-5p derived from silica-exposed macrophages induces fibroblast transdifferentiation.
Wang D, Hao C, Zhang L, Zhang J, Liu S, Li Y, Qu Y, Zhao Y, Huang R, Wei J, Yao W
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Ecotoxicology and environmental safety 2020 Apr 1;192:110253
Abnormal Ribosome Biogenesis Partly Induced p53-Dependent Aortic Medial Smooth Muscle Cell Apoptosis and Oxidative Stress.
Wu Q, Hong J, Wang Z, Hu J, Chen R, Hu Z, Li B, Hu X, Zhang Z, Ruan Y
Oxidative medicine and cellular longevity 2019;2019:7064319
Oxidative medicine and cellular longevity 2019;2019:7064319
Bufei Qingyu Granules Inhibit the Development of Systemic Sclerosis via Notch-1/Jagged-2 Signaling Pathway.
Su M, Tian F, Ouyang B, Wu X, Guo F, Chen H, Zhu X, Chen J, Qian X
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6709278
Evidence-based complementary and alternative medicine : eCAM 2019;2019:6709278
Methane-Rich Saline Counteracts Cholestasis-Induced Liver Damage via Regulating the TLR4/NF-κB/NLRP3 Inflammasome Pathway.
Li Z, Chen D, Jia Y, Feng Y, Wang C, Tong Y, Cui R, Qu K, Liu C, Zhang J
Oxidative medicine and cellular longevity 2019;2019:6565283
Oxidative medicine and cellular longevity 2019;2019:6565283
Isorhamnetin Inhibits Liver Fibrosis by Reducing Autophagy and Inhibiting Extracellular Matrix Formation via the TGF-β1/Smad3 and TGF-β1/p38 MAPK Pathways.
Liu N, Feng J, Lu X, Yao Z, Liu Q, Lv Y, Han Y, Deng J, Zhou Y
Mediators of inflammation 2019;2019:6175091
Mediators of inflammation 2019;2019:6175091
Effects of Ethyl Pyruvate on Bile Duct Ligation-Induced Liver Fibrosis by Regulating Nrf2 Pathway and Proinflammatory Cytokines in Rats.
Zong Y, Zhang M, Li S, Qi W, Li J, Liu T, Yang H, Lu C, Hu X
Gastroenterology research and practice 2019;2019:2969802
Gastroenterology research and practice 2019;2019:2969802
Human colorectal cancer-derived carcinoma associated fibroblasts promote CD44-mediated adhesion of colorectal cancer cells to endothelial cells by secretion of HGF.
Zhang R, Qi F, Shao S, Li G, Feng Y
Cancer cell international 2019;19:192
Cancer cell international 2019;19:192
Exosomal miRNA-139 in cancer-associated fibroblasts inhibits gastric cancer progression by repressing MMP11 expression.
Xu G, Zhang B, Ye J, Cao S, Shi J, Zhao Y, Wang Y, Sang J, Yao Y, Guan W, Tao J, Feng M, Zhang W
International journal of biological sciences 2019;15(11):2320-2329
International journal of biological sciences 2019;15(11):2320-2329
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.
Dias HB, de Oliveira JR, Donadio MVF, Kimura S
PloS one 2019;14(9):e0222202
PloS one 2019;14(9):e0222202
High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia.
Sun Y, Hei M, Fang Z, Tang Z, Wang B, Hu N
Frontiers in cellular neuroscience 2019;13:506
Frontiers in cellular neuroscience 2019;13:506
Liraglutide Improves Non-Alcoholic Fatty Liver Disease In Diabetic Mice By Modulating Inflammatory Signaling Pathways.
Luo Y, Yang P, Li Z, Luo Y, Shen J, Li R, Zheng H, Liang Y, Xia N
Drug design, development and therapy 2019;13:4065-4074
Drug design, development and therapy 2019;13:4065-4074
Dioscin ameliorates peritoneal fibrosis by inhibiting epithelial-to-mesenchymal transition of human peritoneal mesothelial cells via the TLR4/MyD88/NF-κB signaling pathway.
Shao Q, Jiang C, Xia Y, Zhao M, Zhang Q, Jin B, Liu J
International journal of clinical and experimental pathology 2019;12(3):867-875
International journal of clinical and experimental pathology 2019;12(3):867-875
Liraglutide ameliorates nonalcoholic fatty liver disease in diabetic mice via the IRS2/PI3K/Akt signaling pathway.
Yang P, Liang Y, Luo Y, Li Z, Wen Y, Shen J, Li R, Zheng H, Gu HF, Xia N
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1013-1021
Diabetes, metabolic syndrome and obesity : targets and therapy 2019;12:1013-1021
Antiproliferative and Immunoregulatory Effects of Azelaic Acid Against Acute Myeloid Leukemia via the Activation of Notch Signaling Pathway.
Dongdong Z, Jin Y, Yang T, Yang Q, Wu B, Chen Y, Luo Z, Liang L, Liu Y, Xu A, Tong X, Can C, Ding L, Tu H, Tan Y, Jiang H, Liu X, Shen H, Liu L, Pan Y, Wei Y, Zhou F
Frontiers in pharmacology 2019;10:1396
Frontiers in pharmacology 2019;10:1396
Differential regulation of vacuolar H(+) -ATPase subunits by transforming growth factor-β1 in salivary ducts.
Kluge M, Namkoong E, Khakipoor S, Park K, Roussa E
Journal of cellular physiology 2019 Sep;234(9):15061-15079
Journal of cellular physiology 2019 Sep;234(9):15061-15079
The Akt/FoxO/p27(Kip1) axis contributes to the anti-proliferation of pentoxifylline in hypertrophic scars.
Yang F, Chen E, Yang Y, Han F, Han S, Wu G, Zhang M, Zhang J, Han J, Su L, Hu D
Journal of cellular and molecular medicine 2019 Sep;23(9):6164-6172
Journal of cellular and molecular medicine 2019 Sep;23(9):6164-6172
Adenovirus‑mediated overexpression of bone morphogenetic protein‑9 promotes methionine choline deficiency‑induced non‑alcoholic steatohepatitis in non‑obese mice.
Li Q, Liu B, Breitkopf-Heinlein K, Weng H, Jiang Q, Dong P, Dooley S, Xu K, Ding H
Molecular medicine reports 2019 Sep;20(3):2743-2753
Molecular medicine reports 2019 Sep;20(3):2743-2753
Downregulating SynCAM and MPP6 expression is associated with ovarian cancer progression.
Xu F, Si X, Du J, Xu F, Yang A, Zhang C, Zhang X, Yang Y
Oncology letters 2019 Sep;18(3):2477-2483
Oncology letters 2019 Sep;18(3):2477-2483
Exogenous angiotensin (1-7) directly inhibits epithelial-mesenchymal transformation induced by transforming growth factor-β1 in alveolar epithelial cells.
Shao M, Wen ZB, Yang HH, Zhang CY, Xiong JB, Guan XX, Zhong WJ, Jiang HL, Sun CC, Luo XQ, He XF, Zhou Y, Guan CX
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109193
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Sep;117:109193
A novel technique to prepare a single cell suspension of isolated quiescent human hepatic stellate cells.
Zhai X, Wang W, Dou D, Ma Y, Gang D, Jiang Z, Shi B, Jin B
Scientific reports 2019 Sep 4;9(1):12757
Scientific reports 2019 Sep 4;9(1):12757
Altered bile acid composition and disposition in a mouse model of non-alcoholic steatohepatitis.
Suga T, Yamaguchi H, Ogura J, Shoji S, Maekawa M, Mano N
Toxicology and applied pharmacology 2019 Sep 15;379:114664
Toxicology and applied pharmacology 2019 Sep 15;379:114664
Corticosterone Excess-Mediated Mitochondrial Damage Induces Hippocampal Neuronal Autophagy in Mice Following Cold Exposure.
Xu B, Lang L, Li S, Yuan J, Wang J, Yang H, Lian S
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
Animals : an open access journal from MDPI 2019 Sep 14;9(9)
Chrysophanol attenuates airway inflammation and remodeling through nuclear factor-kappa B signaling pathway in asthma.
Song G, Zhang Y, Yu S, Lv W, Guan Z, Sun M, Wang J
Phytotherapy research : PTR 2019 Oct;33(10):2702-2713
Phytotherapy research : PTR 2019 Oct;33(10):2702-2713
Inhibition of vascular neointima hyperplasia by FGF21 associated with FGFR1/Syk/NLRP3 inflammasome pathway in diabetic mice.
Wei W, Li XX, Xu M
Atherosclerosis 2019 Oct;289:132-142
Atherosclerosis 2019 Oct;289:132-142
Effects of ubiquitin-proteasome inhibitor on the expression levels of TNF-α and TGF-β1 in mice with viral myocarditis.
Zhang H, Yu J, Sun H, Zhao Y, Wang J, Zhang J, Meng B
Experimental and therapeutic medicine 2019 Oct;18(4):2799-2804
Experimental and therapeutic medicine 2019 Oct;18(4):2799-2804
SPIO nanoparticle-labeled bone marrow mesenchymal stem cells inhibit pulmonary EndoMT induced by SiO(2).
Jiang R, Liao Y, Yang F, Cheng Y, Dai X, Chao J
Experimental cell research 2019 Oct 1;383(1):111492
Experimental cell research 2019 Oct 1;383(1):111492
Curcumin mitigates the epithelial-to-mesenchymal transition in biliary epithelial cells through upregulating CD109 expression.
Fan J, Wang Q, Zhang Z, Sun L
Drug development research 2019 Nov;80(7):992-999
Drug development research 2019 Nov;80(7):992-999
Long non-coding RNA TUG1 promotes airway remodelling by suppressing the miR-145-5p/DUSP6 axis in cigarette smoke-induced COPD.
Gu W, Yuan Y, Wang L, Yang H, Li S, Tang Z, Li Q
Journal of cellular and molecular medicine 2019 Nov;23(11):7200-7209
Journal of cellular and molecular medicine 2019 Nov;23(11):7200-7209
[Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury].
Zeng Q, He S, Zhong L, Wang L, Cheng F, Zhang H, Hui J, Wei A
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Nov 30;39(11):1329-1336
Nan fang yi ke da xue xue bao = Journal of Southern Medical University 2019 Nov 30;39(11):1329-1336
Artemisinin attenuates the development of atherosclerotic lesions by the regulation of vascular smooth muscle cell phenotype switching.
Du H, Zhao Q, Zang H, Chang C, Li X
Life sciences 2019 Nov 15;237:116943
Life sciences 2019 Nov 15;237:116943
SPARC induces phenotypic modulation of human brain vascular smooth muscle cells via AMPK/mTOR-mediated autophagy.
Li T, Tan X, Zhu S, Zhong W, Huang B, Sun J, Li F, Wang Y
Neuroscience letters 2019 Nov 1;712:134485
Neuroscience letters 2019 Nov 1;712:134485
Emergence of the Dedifferentiated Phenotype in Hepatocyte-Derived Tumors in Mice: Roles of Oncogene-Induced Epigenetic Alterations.
Watanabe K, Yamamoto M, Xin B, Ooshio T, Goto M, Fujii K, Liu Y, Okada Y, Furukawa H, Nishikawa Y
Hepatology communications 2019 May;3(5):697-715
Hepatology communications 2019 May;3(5):697-715
Inhibition of mitochondrial complex I activity attenuates neointimal hyperplasia by inhibiting smooth muscle cell proliferation and migration.
Yin J, Xia W, Wu M, Zhang Y, Huang S, Zhang A, Jia Z
Chemico-biological interactions 2019 May 1;304:73-82
Chemico-biological interactions 2019 May 1;304:73-82
Histone deacetylase-1 as a prognostic factor and mediator of gastric cancer progression by enhancing glycolysis.
Jiang Z, Yang H, Zhang X, Wang Z, Rong R, Wang X
Human pathology 2019 Mar;85:194-201
Human pathology 2019 Mar;85:194-201
NAB 2-Expressing Cancer-Associated Fibroblast Promotes HNSCC Progression.
Choi SY, Oh SY, Kang SH, Kang SM, Kim J, Lee HJ, Kwon TG, Kim JW, Hong SH
Cancers 2019 Mar 19;11(3)
Cancers 2019 Mar 19;11(3)
Ribes diacanthum Pall (RDP) ameliorates UUO-induced renal fibrosis via both canonical and non-canonical TGF-β signaling pathways in mice.
Gu L, Wang Y, Yang G, Tilyek A, Zhang C, Li S, Yu B, Chai C, Cao Z
Journal of ethnopharmacology 2019 Mar 1;231:302-310
Journal of ethnopharmacology 2019 Mar 1;231:302-310
AKR1B10 (Aldo-keto reductase family 1 B10) promotes brain metastasis of lung cancer cells in a multi-organ microfluidic chip model.
Liu W, Song J, Du X, Zhou Y, Li Y, Li R, Lyu L, He Y, Hao J, Ben J, Wang W, Shi H, Wang Q
Acta biomaterialia 2019 Jun;91:195-208
Acta biomaterialia 2019 Jun;91:195-208
Isolation and culture of vascular smooth muscle cells from rat placenta.
He C, Wang M, Yan Z, Zhang S, Liu H
Journal of cellular physiology 2019 Jun;234(6):7675-7682
Journal of cellular physiology 2019 Jun;234(6):7675-7682
Death-associated protein kinase 3 deficiency alleviates vascular calcification via AMPK-mediated inhibition of endoplasmic reticulum stress.
Li KX, Du Q, Wang HP, Sun HJ
European journal of pharmacology 2019 Jun 5;852:90-98
European journal of pharmacology 2019 Jun 5;852:90-98
Epidural adipose tissue-derived mesenchymal stem cell activation induced by lung cancer cells promotes malignancy and EMT of lung cancer.
Wang Y, Chu Y, Ren X, Xiang H, Xi Y, Ma X, Zhu K, Guo Z, Zhou C, Zhang G, Chen B
Stem cell research & therapy 2019 Jun 13;10(1):168
Stem cell research & therapy 2019 Jun 13;10(1):168
The emerging roles of a novel CCCH-type zinc finger protein, ZC3H4, in silica-induced epithelial to mesenchymal transition.
Jiang R, Zhou Z, Liao Y, Yang F, Cheng Y, Huang J, Wang J, Chen H, Zhu T, Chao J
Toxicology letters 2019 Jun 1;307:26-40
Toxicology letters 2019 Jun 1;307:26-40
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.
Xu G, Wang X, Yu H, Wang C, Liu Y, Zhao R, Zhang G
Human & experimental toxicology 2019 Jul;38(7):794-802
Human & experimental toxicology 2019 Jul;38(7):794-802
c‑Jun N‑terminal kinase/transforming growth factor‑β/Smad3 pathway: Is it associated with endoplasmic reticulum stress‑mediated renal interstitial fibrosis?
Liu Y, Shen P, Zhou Y, Tang L, Chai H
Molecular medicine reports 2019 Jul;20(1):755-762
Molecular medicine reports 2019 Jul;20(1):755-762
miR-205-5p suppresses pulmonary vascular smooth muscle cell proliferation by targeting MICAL2-mediated Erk1/2 signaling.
Tao W, Sun W, Zhu H, Zhang J
Microvascular research 2019 Jul;124:43-50
Microvascular research 2019 Jul;124:43-50
Long non-coding RNA and mRNA profile analysis of metformin to reverse the pulmonary hypertension vascular remodeling induced by monocrotaline.
Sun Z, Liu Y, Yu F, Xu Y, Yanli L, Liu N
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108933
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108933
HBOA ameliorates CCl(4)-incuded liver fibrosis through inhibiting TGF-β1/Smads, NF-κB and ERK signaling pathways.
Sun X, Huang X, Zhu X, Liu L, Mo S, Wang H, Wei X, Lu S, Bai F, Wang D, Lin X, Lin J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2019 Jul;115:108901
Inhibitory Effects of Oxymatrine on Transdifferentiation of Neonatal Rat Cardiac Fibroblasts to Myofibroblasts Induced by Aldosterone via Keap1/Nrf2 Signaling Pathways In Vitro.
Yang Y, Chen S, Tao L, Gan S, Luo H, Xu Y, Shen X
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Medical science monitor : international medical journal of experimental and clinical research 2019 Jul 20;25:5375-5388
Peroxisome Proliferator-Activated Receptor-γ Coactivator-1α Inhibits Vascular Calcification Through Sirtuin 3-Mediated Reduction of Mitochondrial Oxidative Stress.
Feng H, Wang JY, Yu B, Cong X, Zhang WG, Li L, Liu LM, Zhou Y, Zhang CL, Gu PL, Wu LL
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Antioxidants & redox signaling 2019 Jul 1;31(1):75-91
Rhynchophylline attenuates allergic bronchial asthma by inhibiting transforming growth factor-β1-mediated Smad and mitogen-activated protein kinase signaling transductions in vivo and in vitro.
Wang M, Li H, Zhao Y, Lv C, Zhou G
Experimental and therapeutic medicine 2019 Jan;17(1):251-259
Experimental and therapeutic medicine 2019 Jan;17(1):251-259
CDH11 promotes liver fibrosis via activation of hepatic stellate cells.
Ruan W, Pan R, Shen X, Nie Y, Wu Y
Biochemical and biophysical research communications 2019 Jan 8;508(2):543-549
Biochemical and biophysical research communications 2019 Jan 8;508(2):543-549
The deregulation of STIM1 and store operative calcium entry impaired aortic smooth muscle cells contractility in aortic medial degeneration.
Hong J, Hu Z, Wu Q, Tang C, Hu J, Chen R, Li B, Wang Z
Bioscience reports 2019 Jan 31;39(1)
Bioscience reports 2019 Jan 31;39(1)
Anti-senescence role of heterozygous fumarate hydratase gene knockout in rat lung fibroblasts in vitro.
Fan Z, Li L, Li X, Zhang M, Dou M, Zhao J, Cao J, Deng X, Zhang M, Li H, Suo Z
Aging 2019 Jan 21;11(2):573-589
Aging 2019 Jan 21;11(2):573-589
Native nanodiscs from blood inhibit pulmonary fibrosis.
Sun A, Lai Z, Zhao M, Mu L, Hu X
Biomaterials 2019 Feb;192:51-61
Biomaterials 2019 Feb;192:51-61
Autophagic flux blockage in alveolar epithelial cells is essential in silica nanoparticle-induced pulmonary fibrosis.
Zhao X, Wei S, Li Z, Lin C, Zhu Z, Sun D, Bai R, Qian J, Gao X, Chen G, Xu Z
Cell death & disease 2019 Feb 12;10(2):127
Cell death & disease 2019 Feb 12;10(2):127
Indoxyl sulfate-induced calcification of vascular smooth muscle cells via the PI3K/Akt/NF-κB signaling pathway.
He X, Jiang H, Gao F, Liang S, Wei M, Chen L
Microscopy research and technique 2019 Dec;82(12):2000-2006
Microscopy research and technique 2019 Dec;82(12):2000-2006
miR-194 suppresses epithelial-mesenchymal transition of retinal pigment epithelial cells by directly targeting ZEB1.
Cui L, Lyu Y, Jin X, Wang Y, Li X, Wang J, Zhang J, Deng Z, Yang N, Zheng Z, Guo Y, Wang C, Mao R, Xu J, Gao F, Jin C, Zhang J, Tian H, Xu GT, Lu L
Annals of translational medicine 2019 Dec;7(23):751
Annals of translational medicine 2019 Dec;7(23):751
Label- and modification-free-based in situ selection of bovine serum albumin specific aptamer.
Wang C, Du X, Xie T, Li H
Journal of separation science 2019 Dec;42(23):3571-3578
Journal of separation science 2019 Dec;42(23):3571-3578
Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats.
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D
Journal of cellular physiology 2019 Dec;234(12):22857-22873
Journal of cellular physiology 2019 Dec;234(12):22857-22873
circPUM1 Promotes Tumorigenesis and Progression of Ovarian Cancer by Sponging miR-615-5p and miR-6753-5p.
Guan X, Zong ZH, Liu Y, Chen S, Wang LL, Zhao Y
Molecular therapy. Nucleic acids 2019 Dec 6;18:882-892
Molecular therapy. Nucleic acids 2019 Dec 6;18:882-892
Salusin-β Promotes Vascular Calcification via Nicotinamide Adenine Dinucleotide Phosphate/Reactive Oxygen Species-Mediated Klotho Downregulation.
Sun H, Zhang F, Xu Y, Sun S, Wang H, Du Q, Gu C, Black SM, Han Y, Tang H
Antioxidants & redox signaling 2019 Dec 20;31(18):1352-1370
Antioxidants & redox signaling 2019 Dec 20;31(18):1352-1370
Galectin-3 Mediates Endothelial-to-Mesenchymal Transition in Pulmonary Arterial Hypertension.
Li T, Zha L, Luo H, Li S, Zhao L, He J, Li X, Qi Q, Liu Y, Yu Z
Aging and disease 2019 Aug;10(4):731-745
Aging and disease 2019 Aug;10(4):731-745
Calhex(231) Alleviates High Glucose-Induced Myocardial Fibrosis via Inhibiting Itch-Ubiquitin Proteasome Pathway in Vitro.
Yuan H, Xu J, Xu X, Gao T, Wang Y, Fan Y, Hu J, Shao Y, Zhao B, Li H, Sun J, Xu C
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344
Biological & pharmaceutical bulletin 2019 Aug 1;42(8):1337-1344
Expression and distribution of PIEZO1 in the mouse urinary tract.
Dalghi MG, Clayton DR, Ruiz WG, Al-Bataineh MM, Satlin LM, Kleyman TR, Ricke WA, Carattino MD, Apodaca G
American journal of physiology. Renal physiology 2019 Aug 1;317(2):F303-F321
American journal of physiology. Renal physiology 2019 Aug 1;317(2):F303-F321
Exploring the Mechanism of Dangguiliuhuang Decoction Against Hepatic Fibrosis by Network Pharmacology and Experimental Validation.
Cao H, Li S, Xie R, Xu N, Qian Y, Chen H, Hu Q, Quan Y, Yu Z, Liu J, Xiang M
Frontiers in pharmacology 2018;9:187
Frontiers in pharmacology 2018;9:187
Salvianolic Acid A Attenuates Endoplasmic Reticulum Stress and Protects Against Cholestasis-Induced Liver Fibrosis via the SIRT1/HSF1 Pathway.
Zhu J, Wang R, Xu T, Zhang S, Zhao Y, Li Z, Wang C, Zhou J, Gao D, Hu Y, Tian X, Yao J
Frontiers in pharmacology 2018;9:1277
Frontiers in pharmacology 2018;9:1277
Monitoring the Process of Endostar-Induced Tumor Vascular Normalization by Non-contrast Intravoxel Incoherent Motion Diffusion-Weighted MRI.
Pan JH, Zhu S, Huang J, Liang J, Zhang D, Zhao X, Ding H, Qin L, Shi C, Luo L, Pan Y
Frontiers in oncology 2018;8:524
Frontiers in oncology 2018;8:524
Inhibition of SIRT2 Alleviates Fibroblast Activation and Renal Tubulointerstitial Fibrosis via MDM2.
He FF, You RY, Ye C, Lei CT, Tang H, Su H, Zhang C
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(2):451-460
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;46(2):451-460
Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats.
Xu J, Wang J, Cheng Y, Li X, He M, Zhu J, Han H, Wei G, Kong H, Xie W, Wang H, Zuo X
BioMed research international 2018;2018:1864107
BioMed research international 2018;2018:1864107
Engagement of circular RNA HECW2 in the nonautophagic role of ATG5 implicated in the endothelial-mesenchymal transition.
Yang L, Han B, Zhang Y, Bai Y, Chao J, Hu G, Yao H
Autophagy 2018;14(3):404-418
Autophagy 2018;14(3):404-418
Zoledronate inhibits fibroblasts' proliferation and activation via targeting TGF-β signaling pathway.
Zhao Z, Shen W, Zhu H, Lin L, Jiang G, Zhu Y, Song H, Wu L
Drug design, development and therapy 2018;12:3021-3031
Drug design, development and therapy 2018;12:3021-3031
Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways.
Feng J, Chen K, Xia Y, Wu L, Li J, Li S, Wang W, Lu X, Liu T, Guo C
Drug design, development and therapy 2018;12:1837-1853
Drug design, development and therapy 2018;12:1837-1853
EDIL3 depletion suppress epithelial-mesenchymal transition of lens epithelial cells via transforming growth factor β pathway.
Zhang R, Wei YH, Zhao CY, Song HY, Shen N, Cui X, Gao X, Qi ZT, Zhong M, Shen W
International journal of ophthalmology 2018;11(1):18-24
International journal of ophthalmology 2018;11(1):18-24
Thymosin β4 suppresses CCl(4) -induced murine hepatic fibrosis by down-regulating transforming growth factor β receptor-II.
Li H, Li Q, Zhang X, Zheng X, Zhang Q, Hao Z
The journal of gene medicine 2018 Sep;20(9):e3043
The journal of gene medicine 2018 Sep;20(9):e3043
Stromal expression of JNK1 and VDR is associated with the prognosis of esophageal squamous cell carcinoma.
Bao Y, Zhang S, Guo Y, Wei X, Zhang Y, Yang Y, Zhang H, Ma M, Yang W
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2018 Sep;20(9):1185-1195
Anterior gradient 2 as a supervisory marker for tumor vessel normalization induced by anti-angiogenic treatment.
Pan F, Li W, Yang W, Yang XY, Liu S, Li X, Zhao X, Ding H, Qin L, Pan Y
Oncology letters 2018 Sep;16(3):3083-3091
Oncology letters 2018 Sep;16(3):3083-3091
Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury.
Liu L, Li Y, Wang Z, Ding F, Cheng Z, Xu Q, Cai Y, Limbu MH, Yang Y, Liu B, Chen P
Experimental cell research 2018 Sep 15;370(2):198-207
Experimental cell research 2018 Sep 15;370(2):198-207
NMDA receptor activation inhibits the antifibrotic effect of BM-MSCs on bleomycin-induced pulmonary fibrosis.
Li X, Li C, Tang Y, Huang Y, Cheng Q, Huang X, Zhao F, Hao C, Feng D, Xu J, Han J, Tang S, Liu W, Yue S, Luo Z
American journal of physiology. Lung cellular and molecular physiology 2018 Sep 1;315(3):L404-L421
American journal of physiology. Lung cellular and molecular physiology 2018 Sep 1;315(3):L404-L421
Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro.
Ning C, Gao X, Wang C, Kong Y, Liu Z, Sun H, Sun P, Huo X, Ma X, Meng Q, Liu K
Regulatory toxicology and pharmacology : RTP 2018 Oct;98:58-68
Regulatory toxicology and pharmacology : RTP 2018 Oct;98:58-68
Octreotide attenuates hepatic fibrosis and hepatic stellate cells proliferation and activation by inhibiting Wnt/β-catenin signaling pathway, c-Myc and cyclin D1.
Zhang C, Liu XQ, Sun HN, Meng XM, Bao YW, Zhang HP, Pan FM, Zhang C
International immunopharmacology 2018 Oct;63:183-190
International immunopharmacology 2018 Oct;63:183-190
LncGata6 maintains stemness of intestinal stem cells and promotes intestinal tumorigenesis.
Zhu P, Wu J, Wang Y, Zhu X, Lu T, Liu B, He L, Ye B, Wang S, Meng S, Fan D, Wang J, Yang L, Qin X, Du Y, Li C, He L, Ren W, Wu X, Tian Y, Fan Z
Nature cell biology 2018 Oct;20(10):1134-1144
Nature cell biology 2018 Oct;20(10):1134-1144
Knockdown of NLRP3 alleviates high glucose or TGFB1-induced EMT in human renal tubular cells.
Song S, Qiu D, Luo F, Wei J, Wu M, Wu H, Du C, Du Y, Ren Y, Chen N, Duan H, Shi Y
Journal of molecular endocrinology 2018 Oct 1;61(3):101-113
Journal of molecular endocrinology 2018 Oct 1;61(3):101-113
Hepatoprotection of auraptene from peels of citrus fruits against thioacetamide-induced hepatic fibrosis in mice by activating farnesoid X receptor.
Gao X, Wang C, Ning C, Liu K, Wang X, Liu Z, Sun H, Ma X, Sun P, Meng Q
Food & function 2018 May 23;9(5):2684-2694
Food & function 2018 May 23;9(5):2684-2694
Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion.
Zhang W, Sha Y, Wei K, Wu C, Ding D, Yang Y, Zhu C, Zhang Y, Ding G, Zhang A, Jia Z, Huang S
Oncotarget 2018 May 11;9(36):24199-24208
Oncotarget 2018 May 11;9(36):24199-24208
circHECTD1 promotes the silica-induced pulmonary endothelial-mesenchymal transition via HECTD1.
Fang S, Guo H, Cheng Y, Zhou Z, Zhang W, Han B, Luo W, Wang J, Xie W, Chao J
Cell death & disease 2018 Mar 14;9(3):396
Cell death & disease 2018 Mar 14;9(3):396
Propranolol prevents liver cirrhosis by inhibiting hepatic stellate cell activation mediated by the PDGFR/Akt pathway.
Ding Q, Li Z, Liu B, Ling L, Tian X, Zhang C
Human pathology 2018 Jun;76:37-46
Human pathology 2018 Jun;76:37-46
Autophagy inhibition attenuates the induction of anti-inflammatory effect of catalpol in liver fibrosis.
Liu Z, Zhu P, Zhang L, Xiong B, Tao J, Guan W, Li C, Chen C, Gu J, Duanmu J, Zhang W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2018 Jul;103:1262-1271
Taurocholic acid is an active promoting factor, not just a biomarker of progression of liver cirrhosis: evidence from a human metabolomic study and in vitro experiments.
Liu Z, Zhang Z, Huang M, Sun X, Liu B, Guo Q, Chang Q, Duan Z
BMC gastroenterology 2018 Jul 11;18(1):112
BMC gastroenterology 2018 Jul 11;18(1):112
Circular RNA DLGAP4 Ameliorates Ischemic Stroke Outcomes by Targeting miR-143 to Regulate Endothelial-Mesenchymal Transition Associated with Blood-Brain Barrier Integrity.
Bai Y, Zhang Y, Han B, Yang L, Chen X, Huang R, Wu F, Chao J, Liu P, Hu G, Zhang JH, Yao H
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Jan 3;38(1):32-50
The Journal of neuroscience : the official journal of the Society for Neuroscience 2018 Jan 3;38(1):32-50
Carnosic acid prevents COL1A2 transcription through the reduction of Smad3 acetylation via the AMPKα1/SIRT1 pathway.
Zhao Y, Shi X, Ding C, Feng D, Li Y, Hu Y, Wang L, Gao D, Tian X, Yao J
Toxicology and applied pharmacology 2018 Jan 15;339:172-180
Toxicology and applied pharmacology 2018 Jan 15;339:172-180
8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo.
Xiao Y, Tian C, Huang T, Han B, Wang M, Ma H, Li Z, Ye X, Li X
Life sciences 2018 Jan 1;192:259-269
Life sciences 2018 Jan 1;192:259-269
Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio.
Zhang M, Hu X, Li S, Lu C, Li J, Zong Y, Qi W, Yang H
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Clinics and research in hepatology and gastroenterology 2018 Feb;42(1):72-81
Epigallocatechin-3-gallate inhibits inflammation and epithelial‑mesenchymal transition through the PI3K/AKT pathway via upregulation of PTEN in asthma.
Yang N, Zhang H, Cai X, Shang Y
International journal of molecular medicine 2018 Feb;41(2):818-828
International journal of molecular medicine 2018 Feb;41(2):818-828
Toxoplasma gondii GRA15(II) effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica.
Xie Y, Wen H, Yan K, Wang S, Wang X, Chen J, Li Y, Xu Y, Zhong Z, Shen J, Chu D
Cellular & molecular immunology 2018 Feb;15(2):120-134
Cellular & molecular immunology 2018 Feb;15(2):120-134
Nanoplatform Assembled from a CD44-Targeted Prodrug and Smart Liposomes for Dual Targeting of Tumor Microenvironment and Cancer Cells.
Lv Y, Xu C, Zhao X, Lin C, Yang X, Xin X, Zhang L, Qin C, Han X, Yang L, He W, Yin L
ACS nano 2018 Feb 27;12(2):1519-1536
ACS nano 2018 Feb 27;12(2):1519-1536
Metformin attenuates motility, contraction, and fibrogenic response of hepatic stellate cells in vivo and in vitro by activating AMP-activated protein kinase.
Li Z, Ding Q, Ling LP, Wu Y, Meng DX, Li X, Zhang CQ
World journal of gastroenterology 2018 Feb 21;24(7):819-832
World journal of gastroenterology 2018 Feb 21;24(7):819-832
Sirt1 activation prevents anti-Thy 1.1 mesangial proliferative glomerulonephritis in the rat through the Nrf2/ARE pathway.
Huang K, Li R, Wei W
European journal of pharmacology 2018 Aug 5;832:138-144
European journal of pharmacology 2018 Aug 5;832:138-144
Chemokine (C-X-C motif) ligand 1 is associated with tumor progression and poor prognosis in patients with colorectal cancer.
Zhuo C, Wu X, Li J, Hu D, Jian J, Chen C, Zheng X, Yang C
Bioscience reports 2018 Aug 31;38(4)
Bioscience reports 2018 Aug 31;38(4)
Lipopolysaccharide enhances TGF-β1 signalling pathway and rat pancreatic fibrosis.
Sun L, Xiu M, Wang S, Brigstock DR, Li H, Qu L, Gao R
Journal of cellular and molecular medicine 2018 Apr;22(4):2346-2356
Journal of cellular and molecular medicine 2018 Apr;22(4):2346-2356
Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking.
Zhao W, Yang A, Chen W, Wang P, Liu T, Cong M, Xu A, Yan X, Jia J, You H
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):1129-1137
Biochimica et biophysica acta. Molecular basis of disease 2018 Apr;1864(4 Pt A):1129-1137
Upregulation of phosphatase and tensin homolog is essential for the effect of 4-aminopyridine on A549/CDDP cells.
Luo Z, Wang J, Li C, Qiu Y, Huang J, Huang Y, Gu H, Wu B, Hu Z, Zhen Y
Molecular medicine reports 2018 Apr;17(4):5996-6001
Molecular medicine reports 2018 Apr;17(4):5996-6001
Inhibition of tumor-promoting stroma to enforce subsequently targeting AT(1)R on tumor cells by pathological inspired micelles.
Zhu Y, Wen L, Shao S, Tan Y, Meng T, Yang X, Liu Y, Liu X, Yuan H, Hu F
Biomaterials 2018 Apr;161:33-46
Biomaterials 2018 Apr;161:33-46
Protective effects of yangonin from an edible botanical Kava against lithocholic acid-induced cholestasis and hepatotoxicity.
Kong Y, Gao X, Wang C, Ning C, Liu K, Liu Z, Sun H, Ma X, Sun P, Meng Q
European journal of pharmacology 2018 Apr 5;824:64-71
European journal of pharmacology 2018 Apr 5;824:64-71
5-aminoisoquinoline improves renal function and fibrosis during recovery phase of cisplatin-induced acute kidney injury in rats.
Quesada A, O'Valle F, Montoro-Molina S, Gómez-Morales M, Caba-Molina M, González JF, de Gracia MC, Osuna A, Vargas F, Wangensteen R
Bioscience reports 2018 Apr 27;38(2)
Bioscience reports 2018 Apr 27;38(2)
Thymoquinone protects against cardiac damage from doxorubicin-induced heart failure in Sprague-Dawley rats.
Pei Z, Hu J, Bai Q, Liu B, Cheng D, Liu H, Na R, Yu Q
RSC advances 2018 Apr 17;8(26):14633-14639
RSC advances 2018 Apr 17;8(26):14633-14639
Serum levels of WNT1-inducible signaling pathway protein-1 (WISP-1): a noninvasive biomarker of renal fibrosis in subjects with chronic kidney disease.
Zhong X, Tu YJ, Li Y, Zhang P, Wang W, Chen SS, Li L, Chung AC, Lan HY, Chen HY, Li GS, Wang L
American journal of translational research 2017;9(6):2920-2932
American journal of translational research 2017;9(6):2920-2932
Carnosic Acid Alleviates BDL-Induced Liver Fibrosis through miR-29b-3p-Mediated Inhibition of the High-Mobility Group Box 1/Toll-Like Receptor 4 Signaling Pathway in Rats.
Zhang S, Wang Z, Zhu J, Xu T, Zhao Y, Zhao H, Tang F, Li Z, Zhou J, Gao D, Tian X, Yao J
Frontiers in pharmacology 2017;8:976
Frontiers in pharmacology 2017;8:976
Double Knockdown of PHD1 and Keap1 Attenuated Hypoxia-Induced Injuries in Hepatocytes.
Liu J, Li Y, Liu L, Wang Z, Shi C, Cheng Z, Zhang X, Ding F, Chen PS
Frontiers in physiology 2017;8:291
Frontiers in physiology 2017;8:291
Gypenosides Ameliorate Carbon Tetrachloride-Induced Liver Fibrosis by Inhibiting the Differentiation of Hepatic Progenitor Cells into Myofibroblasts.
Chen J, Li X, Hu Y, Liu W, Zhou Q, Zhang H, Mu Y, Liu P
The American journal of Chinese medicine 2017;45(5):1061-1074
The American journal of Chinese medicine 2017;45(5):1061-1074
Effects of Total Flavone from Rhododendron simsii Planch. Flower on Postischemic Cardiac Dysfunction and Cardiac Remodeling in Rats.
Cheng X, Zhang J, Chen Z
Evidence-based complementary and alternative medicine : eCAM 2017;2017:5389272
Evidence-based complementary and alternative medicine : eCAM 2017;2017:5389272
Anti-OSM Antibody Inhibits Tubulointerstitial Lesion in a Murine Model of Lupus Nephritis.
Liu Q, Du Y, Li K, Zhang W, Feng X, Hao J, Li H, Liu S
Mediators of inflammation 2017;2017:3038514
Mediators of inflammation 2017;2017:3038514
Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis.
Xu L, Yin L, Tao X, Qi Y, Han X, Xu Y, Song S, Li L, Sun P, Peng J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2017 Sep;107(Pt A):318-328
Pancreatic cancer-derived exosomes promote tumor metastasis and liver pre-metastatic niche formation.
Yu Z, Zhao S, Ren L, Wang L, Chen Z, Hoffman RM, Zhou J
Oncotarget 2017 Sep 8;8(38):63461-63483
Oncotarget 2017 Sep 8;8(38):63461-63483
The Hemoglobin Homolog Cytoglobin in Smooth Muscle Inhibits Apoptosis and Regulates Vascular Remodeling.
Jourd'heuil FL, Xu H, Reilly T, McKellar K, El Alaoui C, Steppich J, Liu YF, Zhao W, Ginnan R, Conti D, Lopez-Soler R, Asif A, Keller RK, Schwarz JJ, Thanh Thuy LT, Kawada N, Long X, Singer HA, Jourd'heuil D
Arteriosclerosis, thrombosis, and vascular biology 2017 Oct;37(10):1944-1955
Arteriosclerosis, thrombosis, and vascular biology 2017 Oct;37(10):1944-1955
High doses of baicalin induces kidney injury and fibrosis through regulating TGF-β/Smad signaling pathway.
Cai Y, Ma W, Xiao Y, Wu B, Li X, Liu F, Qiu J, Zhang G
Toxicology and applied pharmacology 2017 Oct 15;333:1-9
Toxicology and applied pharmacology 2017 Oct 15;333:1-9
Inhibition of airway remodeling and inflammation by isoforskolin in PDGF-induced rat ASMCs and OVA-induced rat asthma model.
Liang X, Wang J, Chen W, Ma X, Wang Y, Nagao N, Weng W, Huang J, Liu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:275-286
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Nov;95:275-286
Codelivery for Paclitaxel and Bcl-2 Conversion Gene by PHB-PDMAEMA Amphiphilic Cationic Copolymer for Effective Drug Resistant Cancer Therapy.
Wang X, Liow SS, Wu Q, Li C, Owh C, Li Z, Loh XJ, Wu YL
Macromolecular bioscience 2017 Nov;17(11)
Macromolecular bioscience 2017 Nov;17(11)
Effect of pioglitazone on the calcification of rat vascular smooth muscle cells through the downregulation of the Wnt/β‑catenin signaling pathway.
Gao M, Chen T, Wu L, Zhao X, Mao H, Xing C
Molecular medicine reports 2017 Nov;16(5):6208-6213
Molecular medicine reports 2017 Nov;16(5):6208-6213
Crocetin inhibits the proliferation, migration and TGF-β(2)-induced epithelial-mesenchymal transition of retinal pigment epithelial cells.
Wang HF, Ma JX, Shang QL, An JB, Chen HT
European journal of pharmacology 2017 Nov 15;815:391-398
European journal of pharmacology 2017 Nov 15;815:391-398
Galectin-3 mediates the pulmonary arterial hypertension-induced right ventricular remodeling through interacting with NADPH oxidase 4.
He J, Li X, Luo H, Li T, Zhao L, Qi Q, Liu Y, Yu Z
Journal of the American Society of Hypertension : JASH 2017 May;11(5):275-289.e2
Journal of the American Society of Hypertension : JASH 2017 May;11(5):275-289.e2
Production of human mutant biologically active hepatocyte growth factor in Chinese hamster ovary cells.
Xu D, Wan A, Peng L, Chen Y, He Y, Yang J, Jin J
Preparative biochemistry & biotechnology 2017 May 28;47(5):489-495
Preparative biochemistry & biotechnology 2017 May 28;47(5):489-495
FAM3B mediates high glucose-induced vascular smooth muscle cell proliferation and migration via inhibition of miR-322-5p.
Zhang W, Chen S, Zhang Z, Wang C, Liu C
Scientific reports 2017 May 23;7(1):2298
Scientific reports 2017 May 23;7(1):2298
Role of heparin in pulmonary cell populations in an in-vitro model of acute lung injury.
Camprubí-Rimblas M, Guillamat-Prats R, Lebouvier T, Bringué J, Chimenti L, Iglesias M, Obiols C, Tijero J, Blanch L, Artigas A
Respiratory research 2017 May 10;18(1):89
Respiratory research 2017 May 10;18(1):89
Highly Selective Targeting of Hepatic Stellate Cells for Liver Fibrosis Treatment Using a d-Enantiomeric Peptide Ligand of Fn14 Identified by Mirror-Image mRNA Display.
Huang L, Xie J, Bi Q, Li Z, Liu S, Shen Q, Li C
Molecular pharmaceutics 2017 May 1;14(5):1742-1753
Molecular pharmaceutics 2017 May 1;14(5):1742-1753
Reactive oxygen species mediate angiotensin II-induced transcytosis of low-density lipoprotein across endothelial cells.
Bian F, Cui J, Zheng T, Jin S
International journal of molecular medicine 2017 Mar;39(3):629-635
International journal of molecular medicine 2017 Mar;39(3):629-635
Generation and characteristics of human Sertoli cell line immortalized by overexpression of human telomerase.
Wen L, Yuan Q, Sun M, Niu M, Wang H, Fu H, Zhou F, Yao C, Wang X, Li Z, He Z
Oncotarget 2017 Mar 7;8(10):16553-16570
Oncotarget 2017 Mar 7;8(10):16553-16570
Dual Function for Mature Vascular Smooth Muscle Cells During Arteriovenous Fistula Remodeling.
Zhao J, Jourd'heuil FL, Xue M, Conti D, Lopez-Soler RI, Ginnan R, Asif A, Singer HA, Jourd'heuil D, Long X
Journal of the American Heart Association 2017 Mar 30;6(4)
Journal of the American Heart Association 2017 Mar 30;6(4)
Secreted phospholipase A2 of Clonorchis sinensis activates hepatic stellate cells through a pathway involving JNK signalling.
Wu Y, Li Y, Shang M, Jian Y, Wang C, Bardeesi AS, Li Z, Chen T, Zhao L, Zhou L, He A, Huang Y, Lv Z, Yu X, Li X
Parasites & vectors 2017 Mar 16;10(1):147
Parasites & vectors 2017 Mar 16;10(1):147
Losartan Attenuates Scar Formation in Filtering Bleb After Trabeculectomy.
Shi H, Wang H, Fu S, Xu K, Zhang X, Xiao Y, Ye W
Investigative ophthalmology & visual science 2017 Mar 1;58(3):1478-1486
Investigative ophthalmology & visual science 2017 Mar 1;58(3):1478-1486
miR-34a promotes fibrosis in aged lungs by inducing alveolarepithelial dysfunctions.
Cui H, Ge J, Xie N, Banerjee S, Zhou Y, Liu RM, Thannickal VJ, Liu G
American journal of physiology. Lung cellular and molecular physiology 2017 Mar 1;312(3):L415-L424
American journal of physiology. Lung cellular and molecular physiology 2017 Mar 1;312(3):L415-L424
NUBPL, a novel metastasis-related gene, promotes colorectal carcinoma cell motility by inducing epithelial-mesenchymal transition.
Wang Y, Wu N, Sun D, Sun H, Tong D, Liu D, Pang B, Li S, Wei J, Dai J, Liu Y, Bai J, Geng J, Fu S, Jin Y
Cancer science 2017 Jun;108(6):1169-1176
Cancer science 2017 Jun;108(6):1169-1176
LncRNA-ATB/microRNA-200a/β-catenin regulatory axis involved in the progression of HCV-related hepatic fibrosis.
Fu N, Zhao SX, Kong LB, Du JH, Ren WG, Han F, Zhang QS, Li WC, Cui P, Wang RQ, Zhang YG, Nan YM
Gene 2017 Jun 30;618:1-7
Gene 2017 Jun 30;618:1-7
Clonorchis sinensis lysophospholipase A upregulates IL-25 expression in macrophages as a potential pathway to liver fibrosis.
Zhou L, Shi M, Zhao L, Lin Z, Tang Z, Sun H, Chen T, Lv Z, Xu J, Huang Y, Yu X
Parasites & vectors 2017 Jun 17;10(1):295
Parasites & vectors 2017 Jun 17;10(1):295
Qi-Zhu-Xie-Zhuo-Fang reduces serum uric acid levels and ameliorates renal fibrosis in hyperuricemic nephropathy rats.
Huijuan W, Xiaoxu C, Rui S, Xinghui L, Beibei T, Jianchun M
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:358-365
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:358-365
CYP2J2 metabolites, epoxyeicosatrienoic acids, attenuate Ang II-induced cardiac fibrotic response by targeting Gα(12/13).
He Z, Yang Y, Wen Z, Chen C, Xu X, Zhu Y, Wang Y, Wang DW
Journal of lipid research 2017 Jul;58(7):1338-1353
Journal of lipid research 2017 Jul;58(7):1338-1353
Conjugation of gold nanoparticles and recombinant human endostatin modulates vascular normalization via interruption of anterior gradient 2-mediated angiogenesis.
Pan F, Yang W, Li W, Yang XY, Liu S, Li X, Zhao X, Ding H, Qin L, Pan Y
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317708547
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017 Jul;39(7):1010428317708547
Knockdown of histidine-rich calcium-binding protein (HRC) suppresses liver fibrosis by inhibiting the activation of hepatic stellate cells.
Liu J, Li M, Gong J, Han P, Wang Y, Li D, Tian D, Liao J
Biology open 2017 Jan 15;6(1):29-34
Biology open 2017 Jan 15;6(1):29-34
Calycosin attenuates triglyceride accumulation and hepatic fibrosis in murine model of non-alcoholic steatohepatitis via activating farnesoid X receptor.
Duan X, Meng Q, Wang C, Liu Z, Liu Q, Sun H, Sun P, Yang X, Huo X, Peng J, Liu K
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:83-92
Phytomedicine : international journal of phytotherapy and phytopharmacology 2017 Feb 15;25:83-92
Interaction network of coexpressed mRNA, miRNA, and lncRNA activated by TGF‑β1 regulates EMT in human pulmonary epithelial cell.
Liu H, Zhao X, Xiang J, Zhang J, Meng C, Zhang J, Li M, Song X, Lv C
Molecular medicine reports 2017 Dec;16(6):8045-8054
Molecular medicine reports 2017 Dec;16(6):8045-8054
Morin enhances hepatic Nrf2 expression in a liver fibrosis rat model.
Sang L, Wang XM, Xu DY, Sang LX, Han Y, Jiang LY
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
World journal of gastroenterology 2017 Dec 21;23(47):8334-8344
Atrial natriuretic peptide: A novel mediator for TGF-β1-induced epithelial-mesenchymal transition in 16HBE-14o and A549 cells.
Chu S, Zhang X, Sun Y, Yu Y, Liang Y, Jiang M, Huang J, Ma L
Peptides 2017 Apr;90:1-9
Peptides 2017 Apr;90:1-9
The role of metastasis-associated in colon cancer 1 (MACC1) in endometrial carcinoma tumorigenesis and progression.
Chen S, Zong ZH, Wu DD, Sun KX, Liu BL, Zhao Y
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
Molecular carcinogenesis 2017 Apr;56(4):1361-1371
MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin.
Zhang ZW, Guo RW, Lv JL, Wang XM, Ye JS, Lu NH, Liang X, Yang LX
Biochemical and biophysical research communications 2017 Apr 29;486(2):414-422
Biochemical and biophysical research communications 2017 Apr 29;486(2):414-422
MDM2 mediates fibroblast activation and renal tubulointerstitial fibrosis via a p53-independent pathway.
Ye C, Tang H, Zhao Z, Lei CT, You CQ, Zhang J, Gao P, He FF, Chen S, Wang YM, Zhang C, Su H
American journal of physiology. Renal physiology 2017 Apr 1;312(4):F760-F768
American journal of physiology. Renal physiology 2017 Apr 1;312(4):F760-F768
Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice.
Wu W, Zhao L, Yang P, Zhou W, Li B, Moorhead JF, Varghese Z, Ruan XZ, Chen Y
PloS one 2016;11(7):e0159512
PloS one 2016;11(7):e0159512
Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy.
Li J, Chen K, Li S, Feng J, Liu T, Wang F, Zhang R, Xu S, Zhou Y, Zhou S, Xia Y, Lu J, Zhou Y, Guo C
Drug design, development and therapy 2016;10:619-30
Drug design, development and therapy 2016;10:619-30
MAD2B promotes tubular epithelial-to-mesenchymal transition and renal tubulointerstitial fibrosis via Skp2.
Tang H, Fan D, Lei CT, Ye C, Gao P, Chen S, Meng XF, Su H, Zhang C
Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
Journal of molecular medicine (Berlin, Germany) 2016 Nov;94(11):1297-1307
A comparison of incidences of bladder neck contracture of 80- versus 180-W GreenLight laser photoselective vaporization of benign prostatic hyperplasia.
Hu B, Song Z, Liu H, Qiao L, Zhao Y, Wang M, Song W, Zhang D, Jin X, Zhang H
Lasers in medical science 2016 Nov;31(8):1573-1581
Lasers in medical science 2016 Nov;31(8):1573-1581
Tet methylcytosine dioxygenase 2 inhibits atherosclerosis via upregulation of autophagy in ApoE-/- mice.
Peng J, Yang Q, Li AF, Li RQ, Wang Z, Liu LS, Ren Z, Zheng XL, Tang XQ, Li GH, Tang ZH, Jiang ZS, Wei DH
Oncotarget 2016 Nov 22;7(47):76423-76436
Oncotarget 2016 Nov 22;7(47):76423-76436
IL-27 inhibits the TGF-β1-induced epithelial-mesenchymal transition in alveolar epithelial cells.
Dong Z, Tai W, Lei W, Wang Y, Li Z, Zhang T
BMC cell biology 2016 Mar 1;17:7
BMC cell biology 2016 Mar 1;17:7
Lymph node metastasis of primary endometrial cancers: Associated proteins revealed by MALDI imaging.
Mittal P, Klingler-Hoffmann M, Arentz G, Winderbaum L, Lokman NA, Zhang C, Anderson L, Scurry J, Leung Y, Stewart CJ, Carter J, Kaur G, Oehler MK, Hoffmann P
Proteomics 2016 Jun;16(11-12):1793-801
Proteomics 2016 Jun;16(11-12):1793-801
MicroRNA-548a-5p promotes proliferation and inhibits apoptosis in hepatocellular carcinoma cells by targeting Tg737.
Zhao G, Wang T, Huang QK, Pu M, Sun W, Zhang ZC, Ling R, Tao KS
World journal of gastroenterology 2016 Jun 21;22(23):5364-73
World journal of gastroenterology 2016 Jun 21;22(23):5364-73
Carboxy-terminal modulator protein attenuated extracellular matrix deposit by inhibiting phospho-Akt, TGF-β1 and α-SMA in kidneys of diabetic mice.
Chen N, Hao J, Li L, Li F, Liu S, Duan H
Biochemical and biophysical research communications 2016 Jun 10;474(4):753-760
Biochemical and biophysical research communications 2016 Jun 10;474(4):753-760
In vitro differentiation of endometrial regenerative cells into smooth muscle cells: Α potential approach for the management of pelvic organ prolapse.
Chen X, Kong X, Liu D, Gao P, Zhang Y, Li P, Liu M
International journal of molecular medicine 2016 Jul;38(1):95-104
International journal of molecular medicine 2016 Jul;38(1):95-104
Gold Nanoparticle-Mediated Targeted Delivery of Recombinant Human Endostatin Normalizes Tumour Vasculature and Improves Cancer Therapy.
Li W, Zhao X, Du B, Li X, Liu S, Yang XY, Ding H, Yang W, Pan F, Wu X, Qin L, Pan Y
Scientific reports 2016 Jul 29;6:30619
Scientific reports 2016 Jul 29;6:30619
Effect of astragalus injection on renal tubular epithelial transdifferentiation in type 2 diabetic mice.
Yi YE, Li SY, Nie YN, Jia DX, Zhang ZH, Wang YF, Wang Q
BMC complementary and alternative medicine 2016 Jul 16;16:222
BMC complementary and alternative medicine 2016 Jul 16;16:222
Clonorchis sinensis lysophospholipase inhibits TGF-β1-induced expression of pro-fibrogenic genes through attenuating the activations of Smad3, JNK2, and ERK1/2 in hepatic stellate cell line LX-2.
Zhou L, Shang M, Shi M, Zhao L, Lin Z, Chen T, Wu Y, Tang Z, Sun H, Yu J, Huang Y, Yu X
Parasitology research 2016 Feb;115(2):643-50
Parasitology research 2016 Feb;115(2):643-50
Mesenchymal stem cell-conditioned media suppresses inflammation-associated overproliferation of pulmonary artery smooth muscle cells in a rat model of pulmonary hypertension.
Liu J, Han Z, Han Z, He Z
Experimental and therapeutic medicine 2016 Feb;11(2):467-475
Experimental and therapeutic medicine 2016 Feb;11(2):467-475
Apobec-1 Complementation Factor (A1CF) Inhibits Epithelial-Mesenchymal Transition and Migration of Normal Rat Kidney Proximal Tubular Epithelial Cells.
Huang L, Wang H, Zhou Y, Ni D, Hu Y, Long Y, Liu J, Peng R, Zhou L, Liu Z, Lyu Z, Mao Z, Hao J, Li Y, Zhou Q
International journal of molecular sciences 2016 Feb 2;17(2)
International journal of molecular sciences 2016 Feb 2;17(2)
PTP1B confers liver fibrosis by regulating the activation of hepatic stellate cells.
Chen PJ, Cai SP, Yang Y, Li WX, Huang C, Meng XM, Li J
Toxicology and applied pharmacology 2016 Feb 1;292:8-18
Toxicology and applied pharmacology 2016 Feb 1;292:8-18
IL-27 attenuates the TGF-β1-induced proliferation, differentiation and collagen synthesis in lung fibroblasts.
Dong Z, Zhao X, Tai W, Lei W, Wang Y, Li Z, Zhang T
Life sciences 2016 Feb 1;146:24-33
Life sciences 2016 Feb 1;146:24-33
Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress.
Shi H, Shi A, Dong L, Lu X, Wang Y, Zhao J, Dai F, Guo X
Clinical nutrition (Edinburgh, Scotland) 2016 Dec;35(6):1366-1373
Clinical nutrition (Edinburgh, Scotland) 2016 Dec;35(6):1366-1373
miR-1273g-3p modulates activation and apoptosis of hepatic stellate cells by directly targeting PTEN in HCV-related liver fibrosis.
Niu X, Fu N, Du J, Wang R, Wang Y, Zhao S, Du H, Wang B, Zhang Y, Sun D, Nan Y
FEBS letters 2016 Aug;590(16):2709-24
FEBS letters 2016 Aug;590(16):2709-24
Quantitative Proteomic Analysis of Escherichia coli Heat-Labile Toxin B Subunit (LTB) with Enterovirus 71 (EV71) Subunit VP1.
Liu L, Ma Y, Zhou H, Wu M
International journal of molecular sciences 2016 Aug 27;17(9)
International journal of molecular sciences 2016 Aug 27;17(9)
The germline-enriched Ppp1r36 promotes autophagy.
Zhang Q, Gao M, Zhang Y, Song Y, Cheng H, Zhou R
Scientific reports 2016 Apr 21;6:24609
Scientific reports 2016 Apr 21;6:24609
C1q/tumor necrosis factor-related protein-6 attenuates post-infarct cardiac fibrosis by targeting RhoA/MRTF-A pathway and inhibiting myofibroblast differentiation.
Lei H, Wu D, Wang JY, Li L, Zhang CL, Feng H, Fu FY, Wu LL
Basic research in cardiology 2015;110(4):35
Basic research in cardiology 2015;110(4):35
Valsartan Promoting Atherosclerotic Plaque Stabilization by Upregulating Renalase: A Potential-Related Gene of Atherosclerosis.
Zhou M, Ma C, Liu W, Liu H, Wang N, Kang Q, Li P
Journal of cardiovascular pharmacology and therapeutics 2015 Sep;20(5):509-19
Journal of cardiovascular pharmacology and therapeutics 2015 Sep;20(5):509-19
Ghrelin Attenuates Liver Fibrosis through Regulation of TGF-β1 Expression and Autophagy.
Mao Y, Zhang S, Yu F, Li H, Guo C, Fan X
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
International journal of molecular sciences 2015 Sep 10;16(9):21911-30
Stroma derived COL6A3 is a potential prognosis marker of colorectal carcinoma revealed by quantitative proteomics.
Qiao J, Fang CY, Chen SX, Wang XQ, Cui SJ, Liu XH, Jiang YH, Wang J, Zhang Y, Yang PY, Liu F
Oncotarget 2015 Oct 6;6(30):29929-46
Oncotarget 2015 Oct 6;6(30):29929-46
CD73 regulates vascular smooth muscle cell functions and facilitates atherosclerotic plaque formation.
Yang J, Jian R, Yu J, Zhi X, Liao X, Yu J, Zhou P
IUBMB life 2015 Nov;67(11):853-60
IUBMB life 2015 Nov;67(11):853-60
Transarterial chemoembolization aggravated peritumoral fibrosis via hypoxia-inducible factor-1α dependent pathway in hepatocellular carcinoma.
Qu K, Yan Z, Wu Y, Chen Y, Qu P, Xu X, Yuan P, Huang X, Xing J, Zhang H, Liu C, Zhang J
Journal of gastroenterology and hepatology 2015 May;30(5):925-32
Journal of gastroenterology and hepatology 2015 May;30(5):925-32
Irradiated fibroblasts promote epithelial-mesenchymal transition and HDGF expression of esophageal squamous cell carcinoma.
Bao CH, Wang XT, Ma W, Wang NN, Un Nesa E, Wang JB, Wang C, Jia YB, Wang K, Tian H, Cheng YF
Biochemical and biophysical research communications 2015 Mar 6;458(2):441-7
Biochemical and biophysical research communications 2015 Mar 6;458(2):441-7
miR-494 suppresses the progression of breast cancer in vitro by targeting CXCR4 through the Wnt/β-catenin signaling pathway.
Song L, Liu D, Wang B, He J, Zhang S, Dai Z, Ma X, Wang X
Oncology reports 2015 Jul;34(1):525-31
Oncology reports 2015 Jul;34(1):525-31
CTRP3 attenuates post-infarct cardiac fibrosis by targeting Smad3 activation and inhibiting myofibroblast differentiation.
Wu D, Lei H, Wang JY, Zhang CL, Feng H, Fu FY, Li L, Wu LL
Journal of molecular medicine (Berlin, Germany) 2015 Dec;93(12):1311-25
Journal of molecular medicine (Berlin, Germany) 2015 Dec;93(12):1311-25
Inhibitory effects of fasudil on renal interstitial fibrosis induced by unilateral ureteral obstruction.
Baba I, Egi Y, Utsumi H, Kakimoto T, Suzuki K
Molecular medicine reports 2015 Dec;12(6):8010-20
Molecular medicine reports 2015 Dec;12(6):8010-20
Anti-pulmonary fibrotic activity of salvianolic acid B was screened by a novel method based on the cyto-biophysical properties.
Liu M, Zheng M, Xu H, Liu L, Li Y, Xiao W, Li J, Ma E
Biochemical and biophysical research communications 2015 Dec 4-11;468(1-2):214-20
Biochemical and biophysical research communications 2015 Dec 4-11;468(1-2):214-20
Human Parechovirus 3 Meningitis and Fatal Leukoencephalopathy.
Bissel SJ, Auer RN, Chiang CH, Kofler J, Murdoch GH, Nix WA, Painter M, Richer M, Sartelet H, Wang G, Wiley CA
Journal of neuropathology and experimental neurology 2015 Aug;74(8):767-77
Journal of neuropathology and experimental neurology 2015 Aug;74(8):767-77
Beta-casomorphin-7 prevents epithelial-mesenchymal transdifferentiation of NRK-52E cells at high glucose level: Involvement of AngII-TGF-β1 pathway.
Zhang W, Song S, Liu F, Liu Y, Zhang Y
Peptides 2015 Aug;70:37-44
Peptides 2015 Aug;70:37-44
Involvement of cAMP-PKA pathway in adenosine A1 and A2A receptor-mediated regulation of acetaldehyde-induced activation of HSCs.
Yang Y, Wang H, Lv X, Wang Q, Zhao H, Yang F, Yang Y, Li J
Biochimie 2015 Aug;115:59-70
Biochimie 2015 Aug;115:59-70
Hesperetin derivative-7 inhibits PDGF-BB-induced hepatic stellate cell activation and proliferation by targeting Wnt/β-catenin pathway.
Lin X, Kong LN, Huang C, Ma TT, Meng XM, He Y, Wang QQ, Li J
International immunopharmacology 2015 Apr;25(2):311-20
International immunopharmacology 2015 Apr;25(2):311-20
Potent effects of dioscin against liver fibrosis.
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, Sun H, Lin Y, Liu K, Peng J
Scientific reports 2015 Apr 8;5:9713
Scientific reports 2015 Apr 8;5:9713
Rosiglitazone inhibits TGF-β 1 induced activation of human Tenon fibroblasts via p38 signal pathway.
Luo YH, Ouyang PB, Tian J, Guo XJ, Duan XC
PloS one 2014;9(8):e105796
PloS one 2014;9(8):e105796
Regulating inflammation using acid-responsive electrospun fibrous scaffolds for skin scarless healing.
Yuan Z, Zhao J, Chen Y, Yang Z, Cui W, Zheng Q
Mediators of inflammation 2014;2014:858045
Mediators of inflammation 2014;2014:858045
Endoplasmic reticulum stress-induced hepatic stellate cell apoptosis through calcium-mediated JNK/P38 MAPK and Calpain/Caspase-12 pathways.
Huang Y, Li X, Wang Y, Wang H, Huang C, Li J
Molecular and cellular biochemistry 2014 Sep;394(1-2):1-12
Molecular and cellular biochemistry 2014 Sep;394(1-2):1-12
Association between the hypomethylation of osteopontin and integrin β3 promoters and vascular smooth muscle cell phenotype switching in great saphenous varicose veins.
Jiang H, Lun Y, Wu X, Xia Q, Zhang X, Xin S, Zhang J
International journal of molecular sciences 2014 Oct 17;15(10):18747-61
International journal of molecular sciences 2014 Oct 17;15(10):18747-61
Identification of colonic fibroblast secretomes reveals secretory factors regulating colon cancer cell proliferation.
Chen SX, Xu XE, Wang XQ, Cui SJ, Xu LL, Jiang YH, Zhang Y, Yan HB, Zhang Q, Qiao J, Yang PY, Liu F
Journal of proteomics 2014 Oct 14;110:155-71
Journal of proteomics 2014 Oct 14;110:155-71
Upregulation of let-7a inhibits vascular smooth muscle cell proliferation in vitro and in vein graft intimal hyperplasia in rats.
Cao H, Hu X, Zhang Q, Wang J, Li J, Liu B, Shao Y, Li X, Zhang J, Xin S
The Journal of surgical research 2014 Nov;192(1):223-33
The Journal of surgical research 2014 Nov;192(1):223-33
Overexpression of c1q/tumor necrosis factor-related protein-3 promotes phosphate-induced vascular smooth muscle cell calcification both in vivo and in vitro.
Zhou Y, Wang JY, Feng H, Wang C, Li L, Wu D, Lei H, Li H, Wu LL
Arteriosclerosis, thrombosis, and vascular biology 2014 May;34(5):1002-10
Arteriosclerosis, thrombosis, and vascular biology 2014 May;34(5):1002-10
Participation of miR-200a in TGF-β1-mediated hepatic stellate cell activation.
Sun X, He Y, Ma TT, Huang C, Zhang L, Li J
Molecular and cellular biochemistry 2014 Mar;388(1-2):11-23
Molecular and cellular biochemistry 2014 Mar;388(1-2):11-23
Effects and mechanism of dehydroepiandrosterone on epithelial-mesenchymal transition in bronchial epithelial cells.
Xu L, Xiang X, Ji X, Wang W, Luo M, Luo S, Li K, Gong S, Liu S, Ma L, Chen P, Li J
Experimental lung research 2014 Jun;40(5):211-21
Experimental lung research 2014 Jun;40(5):211-21
Hyperthermia-conditioned OECs serum-free-conditioned medium induce NSC differentiation into neuron more efficiently by the upregulation of HIF-1 alpha and binding activity.
Wang L, Jiang M, Duan D, Zhao Z, Ge L, Teng X, Liu B, Liu B, Chen P, Lu M
Transplantation 2014 Jun 27;97(12):1225-32
Transplantation 2014 Jun 27;97(12):1225-32
Repression of Smad7 mediated by DNMT1 determines hepatic stellate cell activation and liver fibrosis in rats.
Bian EB, Huang C, Wang H, Chen XX, Zhang L, Lv XW, Li J
Toxicology letters 2014 Jan 13;224(2):175-85
Toxicology letters 2014 Jan 13;224(2):175-85
Antifibrotic effect of curcumin in TGF-β 1-induced myofibroblasts from human oral mucosa.
Zhang SS, Gong ZJ, Li WH, Wang X, Ling TY
Asian Pacific journal of cancer prevention : APJCP 2012;13(1):289-94
Asian Pacific journal of cancer prevention : APJCP 2012;13(1):289-94
MicroRNA-146a modulates TGF-beta1-induced hepatic stellate cell proliferation by targeting SMAD4.
He Y, Huang C, Sun X, Long XR, Lv XW, Li J
Cellular signalling 2012 Oct;24(10):1923-30
Cellular signalling 2012 Oct;24(10):1923-30
β-Casomorphin-7 attenuates the development of nephropathy in type I diabetes via inhibition of epithelial-mesenchymal transition of renal tubular epithelial cells.
Zhang W, Miao J, Ma C, Han D, Zhang Y
Peptides 2012 Aug;36(2):186-91
Peptides 2012 Aug;36(2):186-91
Fusion between cancer cells and myofibroblasts is involved in osteosarcoma.
Yu L, Guo W, Zhao S, Wang F, Xu Y
Oncology letters 2011 Nov;2(6):1083-1087
Oncology letters 2011 Nov;2(6):1083-1087
BCL10 mediates lipopolysaccharide/toll-like receptor-4 signaling through interaction with Pellino2.
Liu Y, Dong W, Chen L, Xiang R, Xiao H, De G, Wang Z, Qi Y
The Journal of biological chemistry 2004 Sep 3;279(36):37436-44
The Journal of biological chemistry 2004 Sep 3;279(36):37436-44
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human placenta tissue were subjected to SDS PAGE followed by western blot with 14395-1-AP(ACTA2 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-ACTA2 (IP:14395-1-AP, 3ug; Detection:14395-1-AP 1:1000) with mouse liver tissue lysate 6000ug.
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human hysteromyoma using 14395-1-AP(ACTA2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ACTA2/smooth muscle actin antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ACTA2/smooth muscle actin. This antibody recognizes human,mouse,rat antigen. The ACTA2/smooth muscle actin antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
