16304-1-AP

antibody from Proteintech Group

Targeting: CHAC2 GCG1

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

16304-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#16304-1-AP, RRID:AB_2229405

Product name

CHAC2 antibody

Antibody type

Polyclonal

Description

CHAC2 antibody (Cat. #16304-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Hypoxia-driven phase separation of the PABP1/eIF4B complex forms stress granules and activates ChaC2 translation to promote polyunsaturated lipids-supported peritoneal metastasis in gastric cancer.

Lin Z, Gao Y, Zhang Q, Yang S, Chen Y, Ding H, Peng W, Zhang X, Nurzat Y, Hu J, Liao W, Xiong B, Xiao M, Zhang X
Cancer letters 2026 May 1;645:218392

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Febuxostat therapy improved the outcomes of cardiorenal syndrome rodent through alleviating xanthine oxidase-induced oxidative stress and mitochondrial dysfunction.

Yang CC, Yue Y, Chen YL, Chiang JY, Wang YT, Huang CR, Cheng BC, Hsu TW, Yip HK
International journal of biological sciences 2025;21(4):1749-1766

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SGLT2 inhibitor downregulated oxidative stress via activating AMPK pathway for cardiorenal (CR) protection in CR syndrome rodent fed with high protein diet.

Yang CC, Chen KH, Yue Y, Cheng BC, Hsu TW, Chiang JY, Chen CH, Liu F, Xiao J, Yip HK
Journal of molecular histology 2024 Oct;55(5):803-823

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NUS1 Variants Cause Lennox-Gastaut Syndrome Related to Unfolded Protein Reaction Activation.

Shen NX, Qu XC, Yu J, Fan CX, Min FL, Li LY, Zhang MR, Li BM, Wang J, He N, Liao WP, Shi YW, Li WB
Molecular neurobiology 2024 Nov;61(11):8518-8530

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CHAC2 promotes lung adenocarcinoma by regulating ROS-mediated MAPK pathway activation.

Peng W, Wen L, Jiang R, Deng J, Chen M
Journal of Cancer 2023;14(8):1309-1320

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Adh Promotes Actinobacillus pleuropneumoniae Survival in Porcine Alveolar Macrophages by Inhibiting CHAC2-Mediated Respiratory Burst and Inflammatory Cytokine Expression.

Zhu J, Zhu R, Jiang H, Li Z, Jiang X, Li F, Zhang F, Feng X, Gu J, Li N, Lei L
Cells 2023 Feb 22;12(5)

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Naringin alleviates acetaminophen-induced acute liver injury by activating Nrf2 via CHAC2 upregulation.

Zhai X, Dai T, Chi Z, Zhao Z, Wu G, Yang S, Dong D
Environmental toxicology 2022 Jun;37(6):1332-1342

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Jurkat cells were subjected to SDS PAGE followed by western blot with 16304-1-AP(CHAC2 antibody) at dilution of 1:500

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of MCF-7 cells, using CHAC2 antibody 16304-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).

Sample type

cell line