CABT-BL2321

antibody from Creative Diagnostics
Targeting: MARCHF1 FLJ20668, MARCH-I, MARCH1, RNF171
Provider product page for CABT-BL2321
No application information provided.

Antibody data

Product number
CABT-BL2321 - Provider product page
Provider
Creative Diagnostics
Product name
Anti-MARCH1 monoclonal antibody, clone MAAG6019
Antibody type
Polyclonal
Description
MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]
MARCHF1 protein structure - CABT-BL2321 shown in red.