Tissue expression
Cell line expression
Protein structure
SARS2
Seryl-tRNA synthetase 2, mitochondrialFLJ20450, mtSerRS, SARS, SARSM, SerRSmt, SERS, SYS
This gene encodes the mitochondrial seryl-tRNA synthethase precursor, a member of the class II tRNA synthetase family. The mature enzyme catalyzes the ligation of Serine to tRNA(Ser) and participates in the biosynthesis of selenocysteinyl-tRNA(sec) in mitochondria. The enzyme contains an N-terminal tRNA binding domain and a core catalytic domain. It functions in a homodimeric form, which is stabilized by tRNA binding. This gene is regulated by a bidirectional promoter that also controls the expression of mitochondrial ribosomal protein S12. Both genes are within the critical interval for the autosomal dominant deafness locus DFNA4 and might be linked to this disease. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Mar 2009]
Top validated antibodies |
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Proteintech Group | 17258-1-AP | 1 references | Polyclonal |
WB
EL
ICC
IHC |
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NSJ Bioreagents | RQ7470 | Polyclonal |
WB
EL
ICC
IHC |
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antibodies-online | ABIN2841954 | 3 references | Polyclonal |
WB
IHC |
|
GeneTex | GTX119452 | Polyclonal |
WB
ICC
IHC
|
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Biorbyt | orb1402182 | Polyclonal |
WB
EL
ICC
IHC |
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Supportive data in Antibodypedia
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Supportive data in Antibodypedia
Data presented on provider website
Data in Antibodypedia (inconclusive)
Recommended by provider