Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 12936-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12936-1-AP, RRID:AB_2267298
- Product name
- NFE2L1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NFE2L1 antibody (Cat. #12936-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Characterization of NFE2L1-616, an isoform of nuclear factor-erythroid-2 related transcription factor-1 that activates antioxidant response element-regulated genes.
Lipid-anchored proteasomes control membrane protein homeostasis.
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Novel mechanistic insight on the neuroprotective effect of berberine: The role of PPARδ for antioxidant action.
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
Long-isoform NFE2L1 silencing inhibits acquisition of malignant phenotypes induced by arsenite in human bronchial epithelial cells.
Silencing of Nrf genes in the human placenta as measured by SDS-PAGE and Western Blotting techniques.
Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice.
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
TRIM59 expression is regulated by Sp1 and Nrf1 in LPS-activated macrophages through JNK signaling pathway.
Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression.
Nrf1 and Nrf2 transcription factors regulate androgen receptor transactivation in prostate cancer cells.
Targeted disruption of nuclear factor erythroid-derived 2-like 1 in osteoblasts reduces bone size and bone formation in mice.
Ho DV, Suryajaya KG, Manh K, Duong AN, Chan JY
Scientific reports 2023 Nov 14;13(1):19900
Scientific reports 2023 Nov 14;13(1):19900
Lipid-anchored proteasomes control membrane protein homeostasis.
Zhang R, Pan S, Zheng S, Liao Q, Jiang Z, Wang D, Li X, Hu A, Li X, Zhu Y, Shen X, Lei J, Zhong S, Zhang X, Huang L, Wang X, Huang L, Shen L, Song BL, Zhao JW, Wang Z, Yang B, Guo X
Science advances 2023 Dec;9(48):eadj4605
Science advances 2023 Dec;9(48):eadj4605
A dual Keap1 and p47(phox) inhibitor Ginsenoside Rb1 ameliorates high glucose/ox-LDL-induced endothelial cell injury and atherosclerosis.
Wang ZC, Niu KM, Wu YJ, Du KR, Qi LW, Zhou YB, Sun HJ
Cell death & disease 2022 Sep 26;13(9):824
Cell death & disease 2022 Sep 26;13(9):824
Novel mechanistic insight on the neuroprotective effect of berberine: The role of PPARδ for antioxidant action.
Shou JW, Li XX, Tang YS, Lim-Ho Kong B, Wu HY, Xiao MJ, Cheung CK, Shaw PC
Free radical biology & medicine 2022 Mar;181:62-71
Free radical biology & medicine 2022 Mar;181:62-71
The transcript ENST00000444125 of lncRNA LINC01503 promotes cancer stem cell properties of glioblastoma cells via reducing FBXW1 mediated GLI2 degradation.
Wei P, Jiang J, Xiao M, Zeng M, Liu X, Zhao B, Chen F
Experimental cell research 2022 Mar 1;412(1):113009
Experimental cell research 2022 Mar 1;412(1):113009
Long-isoform NFE2L1 silencing inhibits acquisition of malignant phenotypes induced by arsenite in human bronchial epithelial cells.
Li Y, Sun R, Fang X, Ruan Y, Hu Y, Wang K, Liu J, Wang H, Pi J, Chen Y, Xu Y
Ecotoxicology and environmental safety 2022 Mar 1;232:113268
Ecotoxicology and environmental safety 2022 Mar 1;232:113268
Silencing of Nrf genes in the human placenta as measured by SDS-PAGE and Western Blotting techniques.
Yap YW, Hannan NJ, Wallace EM, Marshall SA
Placenta 2022 Feb;118:70-74
Placenta 2022 Feb;118:70-74
Nfe2l1 deficiency mitigates streptozotocin-induced pancreatic β-cell destruction and development of diabetes in male mice.
Bao S, Zheng H, Chen C, Zhang Y, Bao L, Yang B, Hou Y, Chen Y, Zhang Q, Pi J, Fu J
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Dec;158:112633
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2021 Dec;158:112633
PTEN status determines chemosensitivity to proteasome inhibition in cholangiocarcinoma.
Jiang TY, Pan YF, Wan ZH, Lin YK, Zhu B, Yuan ZG, Ma YH, Shi YY, Zeng TM, Dong LW, Tan YX, Wang HY
Science translational medicine 2020 Sep 23;12(562)
Science translational medicine 2020 Sep 23;12(562)
TRIM59 expression is regulated by Sp1 and Nrf1 in LPS-activated macrophages through JNK signaling pathway.
An Y, Ni Y, Xu Z, Shi S, He J, Liu Y, Deng KY, Fu M, Jiang M, Xin HB
Cellular signalling 2020 Mar;67:109522
Cellular signalling 2020 Mar;67:109522
Long isoforms of NRF1 negatively regulate adipogenesis via suppression of PPARγ expression.
Xue P, Hou Y, Zuo Z, Wang Z, Ren S, Dong J, Fu J, Wang H, Andersen ME, Zhang Q, Xu Y, Pi J
Redox biology 2020 Feb;30:101414
Redox biology 2020 Feb;30:101414
Nrf1 and Nrf2 transcription factors regulate androgen receptor transactivation in prostate cancer cells.
Schultz MA, Hagan SS, Datta A, Zhang Y, Freeman ML, Sikka SC, Abdel-Mageed AB, Mondal D
PloS one 2014;9(1):e87204
PloS one 2014;9(1):e87204
Targeted disruption of nuclear factor erythroid-derived 2-like 1 in osteoblasts reduces bone size and bone formation in mice.
Kim J, Xing W, Wergedal J, Chan JY, Mohan S
Physiological genomics 2010 Jan 8;40(2):100-10
Physiological genomics 2010 Jan 8;40(2):100-10
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The NFE2L1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NFE2L1. This antibody recognizes human, mouse, rat antigen. The NFE2L1 antibody has been validated for the following applications: ELISA, WB analysis.