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- Antigen structure
- References [15]
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- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 12956-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12956-1-AP, RRID:AB_2078477
- Product name
- LIPA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated LIPA antibody (Cat. #12956-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ANXA2-mediated Phagocytosis Generates AR(+) Macrophages to Confer Enzalutamide Resistance in Prostate Cancer.
STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma.
Transcriptional regulation of disease-relevant microglial activation programs.
Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice.
Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV.
The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation.
Cross-tissue multi-omics analyses reveal the gut microbiota's absence impacts organ morphology, immune homeostasis, bile acid and lipid metabolism.
Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15.
CD276-dependent efferocytosis by tumor-associated macrophages promotes immune evasion in bladder cancer.
CircRNA-Associated ceRNA Network Reveals Focal Adhesion and Metabolism Pathways in Neuropathic Pain.
Moderate Treadmill Exercise Alleviates NAFLD by Regulating the Biogenesis and Autophagy of Lipid Droplet.
Morroniside, a novel GATA3 binding molecule, inhibits hepatic stellate cells activation by enhancing lysosomal acid lipase expression.
Molecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver.
Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1-mediated MAPK signaling.
Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes.
Luo Y, Luo T, Li L, Sun Q, Li D, Huang S, Li Z, Lin W, Ou Y, Du T, Peng S, Xu K, Cheng B, Huang H
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 16;:e75290
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Apr 16;:e75290
STBD1 mediates the crosstalk between glycogen and lipid droplets in clear cell renal cell carcinoma.
Wang H, Xiao T, Zhuang H, Liu Y, Jin K, Li J, Li J, Gao Y, Yue D, Cui W, Xu Q, Pan J, Liu K, Wang Y, Chen R, Li H
Cell reports 2025 Oct 28;44(10):116429
Cell reports 2025 Oct 28;44(10):116429
Transcriptional regulation of disease-relevant microglial activation programs.
McQuade A, Mishra R, Hagan V, Liang W, Colias PJ, Castillo VC, Lubin JP, Haage V, Marshe V, Fujita M, Gomes L, Ta T, Teter O, Chasins SE, De Jager PL, Nuñez JK, Kampmann M
bioRxiv : the preprint server for biology 2025 Oct 27;
bioRxiv : the preprint server for biology 2025 Oct 27;
Deletion of ABIN1-LIR motifs impairs hepatic lipid homeostasis and mitophagy via AMPK-TFEB axis in mice.
Huber LS, Merline R, Zeng-Brouwers J, Vutukuri R, Kraus N, Ortiz C, Guenther S, Buhl EM, Hahnefeld L, Gurke R, Bein J, Karimova M, Wurzel P, Boor P, Welsch C, Wild P, Pfeilschifter J, Kögel D, Wygrecka M, Trebicka J, Bartoszewski R, Dikic I, Schaefer L
American journal of physiology. Cell physiology 2025 Nov 1;329(5):C1360-C1379
American journal of physiology. Cell physiology 2025 Nov 1;329(5):C1360-C1379
Hepatic lipid remodeling in cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by phospholipase A2 group XV.
Davidson JW, Jain R, Kizzar T, Geoghegan G, Nesbitt DJ, Cavanagh A, Abe A, Nyame K, Hunger A, Chao X, James I, Walesewicz H, Baldwin DA, Wade G, Michorowska S, Verma R, Schueler K, Hinkovska-Galcheva V, Shishkova E, Ding WX, Coon JJ, Shayman JA, Abu-Remaileh M, Simcox JA
Cell metabolism 2025 Jun 3;37(6):1413-1425.e6
Cell metabolism 2025 Jun 3;37(6):1413-1425.e6
The cholesterol metabolite 25-hydroxycholesterol suppresses porcine deltacoronavirus via lipophagy inhibition and mTORC1 modulation.
Zhang JL, Wang XF, Li JL, Duan C, Wang JF
Veterinary research 2025 Jan 31;56(1):23
Veterinary research 2025 Jan 31;56(1):23
Cross-tissue multi-omics analyses reveal the gut microbiota's absence impacts organ morphology, immune homeostasis, bile acid and lipid metabolism.
Shen J, Liang W, Zhao R, Chen Y, Liu Y, Cheng W, Chai T, Zhang Y, Chen S, Liu J, Chen X, Deng Y, Zhang Z, Huang Y, Yang H, Pang L, Qiu Q, Deng H, Pan S, Wang L, Ye J, Luo W, Jiang X, Huang X, Li W, Leung EL, Zhang L, Huang L, Yang Z, Chen R, Mei J, Yue Z, Wei H, Karsten K, Han L, Fang X
iMeta 2025 Feb;4(1):e272
iMeta 2025 Feb;4(1):e272
Modulation of hepatic transcription factor EB activity during cold exposure uncovers direct regulation of bis(monoacylglycero)phosphate lipids by Pla2g15.
Davidson JW, Jain R, Kizzar T, Geoghegan G, Nesbitt DJ, Cavanagh A, Abe A, Nyame K, Hunger A, Chao X, James I, Von Bank H, Baldwin DA, Wade G, Michorowska S, Verma R, Scheuler K, Hinkovska-Galcheva V, Shishkova E, Ding WX, Coon JJ, Shayman JA, Abu-Remaileh M, Simcox JA
bioRxiv : the preprint server for biology 2025 Feb 19;
bioRxiv : the preprint server for biology 2025 Feb 19;
CD276-dependent efferocytosis by tumor-associated macrophages promotes immune evasion in bladder cancer.
Cheng M, Chen S, Li K, Wang G, Xiong G, Ling R, Zhang C, Zhang Z, Han H, Chen Z, Wang X, Liang Y, Tian G, Zhou R, Zhu Y, Ma J, Liu J, Lin S, Xu H, Chen D, Li Y, Peng L
Nature communications 2024 Apr 1;15(1):2818
Nature communications 2024 Apr 1;15(1):2818
CircRNA-Associated ceRNA Network Reveals Focal Adhesion and Metabolism Pathways in Neuropathic Pain.
Wang K, Bao JP, Zhou ZM, Mao L, Wu XT
Journal of oncology 2022;2022:7246904
Journal of oncology 2022;2022:7246904
Moderate Treadmill Exercise Alleviates NAFLD by Regulating the Biogenesis and Autophagy of Lipid Droplet.
Yang Y, Li X, Liu Z, Ruan X, Wang H, Zhang Q, Cao L, Song L, Chen Y, Sun Y
Nutrients 2022 Nov 20;14(22)
Nutrients 2022 Nov 20;14(22)
Morroniside, a novel GATA3 binding molecule, inhibits hepatic stellate cells activation by enhancing lysosomal acid lipase expression.
An L, Zhang M, Lin Y, Jiang T, Xu K, Xiao S, Cai L, Kwan HY, Liu Z, Su T
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154199
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Aug;103:154199
Molecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver.
Carotti S, Lettieri-Barbato D, Piemonte F, Ruggiero S, Rosina M, Zalfa F, Zingariello M, Arciprete F, Valentini F, Francesconi M, D'Amico J, De Vincentis A, Baiocchini A, Perrone G, Antonelli-Incalzi R, Morini S, Picardi A, Aquilano K, Vespasiani-Gentilucci U
Cell death & disease 2021 Nov 18;12(12):1092
Cell death & disease 2021 Nov 18;12(12):1092
Squalene epoxidase promotes colorectal cancer cell proliferation through accumulating calcitriol and activating CYP24A1-mediated MAPK signaling.
He L, Li H, Pan C, Hua Y, Peng J, Zhou Z, Zhao Y, Lin M
Cancer communications (London, England) 2021 Aug;41(8):726-746
Cancer communications (London, England) 2021 Aug;41(8):726-746
Evidence for a Novel Regulatory Interaction Involving Cyclin D1, Lipid Droplets, Lipolysis, and Cell Cycle Progression in Hepatocytes.
Wu H, Ploeger JM, Kamarajugadda S, Mashek DG, Mashek MT, Manivel JC, Shekels LL, Lapiro JL, Albrecht JH
Hepatology communications 2019 Mar;3(3):406-422
Hepatology communications 2019 Mar;3(3):406-422
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Y79 cells were subjected to SDS PAGE followed by western blot with 12956-1-AP(LIPA antibody) at dilution of 1:400
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The LIPA antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human LIPA. This antibody recognizes human,mouse,rat antigen. The LIPA antibody has been validated for the following applications: ELISA, WB, IHC analysis.
