Antibody data
- Antibody Data
- Antigen structure
- References [14]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 13048-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13048-1-AP, RRID:AB_10640157
- Product name
- Glypican 4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated Glypican 4 antibody (Cat. #13048-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Glypican-4 serum levels are associated with cognitive dysfunction and vascular risk factors in Parkinson's disease.
Heparan sulfate regulates amphiregulin signaling towards reparative lung mesenchymal cells during influenza A infection.
Investigation of Glypican-4 and -6 by Infrared Spectral Imaging during the Hair Growth Cycle.
Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.
Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.
Neuronal Glypican4 promotes mossy fiber sprouting through the mTOR pathway after pilocarpine-induced status epilepticus in mice.
Transient astrocytic mGluR5 expression drives synaptic plasticity and subsequent chronic pain in mice.
Activity-dependent modulation of synapse-regulating genes in astrocytes.
LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ.
CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.
Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice.
Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation.
Expression of Glypican-4 in the brains of epileptic patients and epileptic animals and its effects on epileptic seizures.
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors.
Tatenhorst L, Maass F, Paul H, Dambeck V, Bähr M, Dono R, Lingor P
Scientific reports 2024 Feb 29;14(1):5005
Scientific reports 2024 Feb 29;14(1):5005
Heparan sulfate regulates amphiregulin signaling towards reparative lung mesenchymal cells during influenza A infection.
Loffredo LF, Surpur A, Ringham OR, Li F, de Los Santos-Alexis K, Arpaia N
bioRxiv : the preprint server for biology 2024 Apr 28;
bioRxiv : the preprint server for biology 2024 Apr 28;
Investigation of Glypican-4 and -6 by Infrared Spectral Imaging during the Hair Growth Cycle.
Colin-Pierre C, Untereiner V, Sockalingum GD, Ramont L, Brézillon S
International journal of molecular sciences 2023 Feb 21;24(5)
International journal of molecular sciences 2023 Feb 21;24(5)
Cocaine preference and neuroadaptations are maintained by astrocytic NMDA receptors in the nucleus accumbens.
Shelkar GP, Gandhi PJ, Liu J, Dravid SM
Science advances 2022 Jul 22;8(29):eabo6574
Science advances 2022 Jul 22;8(29):eabo6574
Synaptic hyperexcitability of cytomegalic pyramidal neurons contributes to epileptogenesis in tuberous sclerosis complex.
Wu X, Sosunov AA, Lado W, Teoh JJ, Ham A, Li H, Al-Dalahmah O, Gill BJA, Arancio O, Schevon CA, Frankel WN, McKhann GM 2nd, Sulzer D, Goldman JE, Tang G
Cell reports 2022 Jul 19;40(3):111085
Cell reports 2022 Jul 19;40(3):111085
Neuronal Glypican4 promotes mossy fiber sprouting through the mTOR pathway after pilocarpine-induced status epilepticus in mice.
Ma KG, Hu HB, Zhou JS, Ji C, Yan QS, Peng SM, Ren LD, Yang BN, Xiao XL, Ma YB, Wu F, Si KW, Wu XL, Liu JX
Experimental neurology 2022 Jan;347:113918
Experimental neurology 2022 Jan;347:113918
Transient astrocytic mGluR5 expression drives synaptic plasticity and subsequent chronic pain in mice.
Danjo Y, Shigetomi E, Hirayama YJ, Kobayashi K, Ishikawa T, Fukazawa Y, Shibata K, Takanashi K, Parajuli B, Shinozaki Y, Kim SK, Nabekura J, Koizumi S
The Journal of experimental medicine 2022 Apr 4;219(4)
The Journal of experimental medicine 2022 Apr 4;219(4)
Activity-dependent modulation of synapse-regulating genes in astrocytes.
Farhy-Tselnicker I, Boisvert MM, Liu H, Dowling C, Erikson GA, Blanco-Suarez E, Farhy C, Shokhirev MN, Ecker JR, Allen NJ
eLife 2021 Sep 8;10
eLife 2021 Sep 8;10
LRRTMs Organize Synapses through Differential Engagement of Neurexin and PTPσ.
Roppongi RT, Dhume SH, Padmanabhan N, Silwal P, Zahra N, Karimi B, Bomkamp C, Patil CS, Champagne-Jorgensen K, Twilley RE, Zhang P, Jackson MF, Siddiqui TJ
Neuron 2020 Apr 8;106(1):108-125.e12
Neuron 2020 Apr 8;106(1):108-125.e12
CD36 inhibits β-catenin/c-myc-mediated glycolysis through ubiquitination of GPC4 to repress colorectal tumorigenesis.
Fang Y, Shen ZY, Zhan YZ, Feng XC, Chen KL, Li YS, Deng HJ, Pan SM, Wu DH, Ding Y
Nature communications 2019 Sep 4;10(1):3981
Nature communications 2019 Sep 4;10(1):3981
Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice.
Lu IL, Chen C, Tung CY, Chen HH, Pan JP, Chang CH, Cheng JS, Chen YA, Wang CH, Huang CW, Kang YN, Chang HY, Li LL, Chang KP, Shih YH, Lin CH, Kwan SY, Tsai JW
Nature communications 2018 Jun 27;9(1):2498
Nature communications 2018 Jun 27;9(1):2498
Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation.
Farhy-Tselnicker I, van Casteren ACM, Lee A, Chang VT, Aricescu AR, Allen NJ
Neuron 2017 Oct 11;96(2):428-445.e13
Neuron 2017 Oct 11;96(2):428-445.e13
Expression of Glypican-4 in the brains of epileptic patients and epileptic animals and its effects on epileptic seizures.
Xiong Y, Zhang Y, Zheng F, Yang Y, Xu X, Wang W, Zhu B, Wang X
Biochemical and biophysical research communications 2016 Sep 9;478(1):241-246
Biochemical and biophysical research communications 2016 Sep 9;478(1):241-246
Astrocyte glypicans 4 and 6 promote formation of excitatory synapses via GluA1 AMPA receptors.
Allen NJ, Bennett ML, Foo LC, Wang GX, Chakraborty C, Smith SJ, Barres BA
Nature 2012 May 27;486(7403):410-4
Nature 2012 May 27;486(7403):410-4
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The Glypican 4 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Glypican 4. This antibody recognizes human,mouse,rat antigen. The Glypican 4 antibody has been validated for the following applications: ELISA, WB analysis.