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- Antibody Data
- Antigen structure
- References [8]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 15452-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15452-1-AP, RRID:AB_2101886
- Product name
- FA2H antibody
- Antibody type
- Polyclonal
- Description
- FA2H antibody (Cat. #15452-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references FA2H controls cool temperature sensing through modifying membrane sphingolipids in Drosophila.
Perfluorooctanoic acid (PFOA) as a stimulator of estrogen receptor-negative breast cancer MDA-MB-231 cell aggressiveness: Evidence for involvement of fatty acid 2-hydroxylase (FA2H) in the stimulated cell migration.
Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis.
Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy.
Cell Lineage-Based Stratification for Glioblastoma.
Fatty acid 2-hydroxylase (FA2H) as a stimulatory molecule responsible for breast cancer cell migration.
FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control.
Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.
Li Q, Chen L, Yang L, Zhang P
Current biology : CB 2024 Mar 11;34(5):997-1009.e6
Current biology : CB 2024 Mar 11;34(5):997-1009.e6
Perfluorooctanoic acid (PFOA) as a stimulator of estrogen receptor-negative breast cancer MDA-MB-231 cell aggressiveness: Evidence for involvement of fatty acid 2-hydroxylase (FA2H) in the stimulated cell migration.
Sakai G, Hirao-Suzuki M, Koga T, Kobayashi T, Kamishikiryo J, Tanaka M, Fujii K, Takiguchi M, Sugihara N, Toda A, Takeda S
The Journal of toxicological sciences 2022;47(4):159-168
The Journal of toxicological sciences 2022;47(4):159-168
Dysregulated ceramides metabolism by fatty acid 2-hydroxylase exposes a metabolic vulnerability to target cancer metastasis.
Zhou X, Huang F, Ma G, Wei W, Wu N, Liu Z
Signal transduction and targeted therapy 2022 Oct 24;7(1):370
Signal transduction and targeted therapy 2022 Oct 24;7(1):370
Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy.
Xie XP, Laks DR, Sun D, Ganbold M, Wang Z, Pedraza AM, Bale T, Tabar V, Brennan C, Zhou X, Parada LF
Developmental cell 2022 Jan 10;57(1):32-46.e8
Developmental cell 2022 Jan 10;57(1):32-46.e8
Cell Lineage-Based Stratification for Glioblastoma.
Wang Z, Sun D, Chen YJ, Xie X, Shi Y, Tabar V, Brennan CW, Bale TA, Jayewickreme CD, Laks DR, Alcantara Llaguno S, Parada LF
Cancer cell 2020 Sep 14;38(3):366-379.e8
Cancer cell 2020 Sep 14;38(3):366-379.e8
Fatty acid 2-hydroxylase (FA2H) as a stimulatory molecule responsible for breast cancer cell migration.
Hirao-Suzuki M, Koga T, Sakai G, Kobayashi T, Ishii Y, Miyazawa H, Takiguchi M, Sugihara N, Toda A, Ohara M, Takeda S
Biochemical and biophysical research communications 2020 Oct 15;531(2):215-222
Biochemical and biophysical research communications 2020 Oct 15;531(2):215-222
FA2H Exhibits Tumor Suppressive Roles on Breast Cancers via Cancer Stemness Control.
Dai X, Zhang S, Cheng H, Cai D, Chen X, Huang Z
Frontiers in oncology 2019;9:1089
Frontiers in oncology 2019;9:1089
Substrate-based fragment identification for the development of selective, nonpeptidic inhibitors of striatal-enriched protein tyrosine phosphatase.
Baguley TD, Xu HC, Chatterjee M, Nairn AC, Lombroso PJ, Ellman JA
Journal of medicinal chemistry 2013 Oct 10;56(19):7636-50
Journal of medicinal chemistry 2013 Oct 10;56(19):7636-50
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 15452-1-AP(FA2H antibody) at dilution of 1:600
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 15452-1-AP(FA2H antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The FA2H antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human FA2H. This antibody recognizes human,mouse,rat antigen. The FA2H antibody has been validated for the following applications: ELISA, WB, IHC analysis.
