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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- 12357-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12357-2-AP, RRID:AB_2144259
- Product name
- MRRF antibody
- Antibody type
- Polyclonal
- Description
- MRRF antibody (Cat. #12357-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ZLN005 alleviates PBDE-47 induced impairment of mitochondrial translation and neurotoxicity through PGC-1α/ERRα axis.
Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Muscle denervation reduces mitochondrial biogenesis and mitochondrial translation factor expression in mice.
Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle.
Tian Z, Li J, Tang H, Liu W, Hou H, Wang C, Li D, Chen G, Xia T, Wang A
Journal of hazardous materials 2024 Jun 5;471:134331
Journal of hazardous materials 2024 Jun 5;471:134331
Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.
Li D, Zhao Q, Xie L, Wang C, Tian Z, Tang H, Xia T, Wang A
The Science of the total environment 2023 Apr 15;869:161738
The Science of the total environment 2023 Apr 15;869:161738
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Shu Y, Hao Y, Feng J, Liu H, Li ST, Feng J, Jiang Z, Ye L, Zhou Y, Sun Y, Zhou Z, Wei H, Gao P, Zhang H, Sun L
The EMBO journal 2022 Dec 1;41(23):e111550
The EMBO journal 2022 Dec 1;41(23):e111550
Muscle denervation reduces mitochondrial biogenesis and mitochondrial translation factor expression in mice.
Yokokawa T, Mori R, Suga T, Isaka T, Hayashi T, Fujita S
Biochemical and biophysical research communications 2020 Jun 18;527(1):146-152
Biochemical and biophysical research communications 2020 Jun 18;527(1):146-152
Exercise-induced mitochondrial biogenesis coincides with the expression of mitochondrial translation factors in murine skeletal muscle.
Yokokawa T, Kido K, Suga T, Isaka T, Hayashi T, Fujita S
Physiological reports 2018 Oct;6(20):e13893
Physiological reports 2018 Oct;6(20):e13893
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human lung tissue were subjected to SDS PAGE followed by western blot with 12357-2-AP(MRRF antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using MRRF antibody 12357-2-AP at 1:50 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human pancreas cancer using 12357-2-AP(MRRF antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
