Antibody data
- Antibody Data
- Antigen structure
- References [2]
- Comments [0]
- Validations
- ELISA [1]
- Blocking/Neutralizing [1]
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Validation data
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- Product number
- AF1587 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Goat Polyclonal IL-28A/IFN-lambda 2 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human IL-28A/IFN-lambda 2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 60% cross-reactivity with human IL-28B/IFN-lambda 3 is observed. In direct ELISAs, approximately 30% cross-reactivity with recombinant human IL-29 and less than 5% cross-reactivity with recombinant mouse IL-28 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Submitted references Interleukin-28A triggers wound healing migration of bladder cancer cells via NF-κB-mediated MMP-9 expression inducing the MAPK pathway.
Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferon-λ genes produced anti-tumour effects.
Lee SJ, Lim JH, Choi YH, Kim WJ, Moon SK
Cellular signalling 2012 Sep;24(9):1734-42
Cellular signalling 2012 Sep;24(9):1734-42
Adenoviruses-mediated transduction of human oesophageal carcinoma cells with the interferon-λ genes produced anti-tumour effects.
Li Q, Kawamura K, Okamoto S, Fujie H, Numasaki M, Namba M, Nagata M, Shimada H, Kobayashi H, Tagawa M
British journal of cancer 2011 Oct 25;105(9):1302-12
British journal of cancer 2011 Oct 25;105(9):1302-12
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Human IL-28A/IFN-?2 ELISA Standard Curve. Human IL-28A/IFN-?2 ELISA Standard Curve.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- IL-28A/IFN-?2 Inhibition of EMCV-induced Cytopathy and Neutralization by Human IL-28A/IFN-?2 Antibody. IL-28A/IFN-?2 Inhibition of EMCV-induced Cytopathy and Neutralization by Human IL-28A/IFN-?2 Antibody.