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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 15441-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15441-1-AP, RRID:AB_2174457
- Product name
- PAF1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated PAF1 antibody (Cat. #15441-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The dimeric deubiquitinase USP28 integrates 53BP1 and MYC functions to limit DNA damage.
SARS-CoV-2 variants evolve convergent strategies to remodel the host response.
CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation.
Identification of PDCD2 as a Candidate Target of Andrographolide That Arrests the Tumor Cell Cycle by Human Proteome-Scale Screening.
Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine.
Novel role of PAF1 in attenuating radiosensitivity in cervical cancer by inhibiting IER5 transcription.
The Paf1 complex transcriptionally regulates the mitochondrial-anchored protein Atg32 leading to activation of mitophagy.
Jin C, Einig E, Xu W, Kollampally RB, Schlosser A, Flentje M, Popov N
Nucleic acids research 2024 Apr 12;52(6):3011-3030
Nucleic acids research 2024 Apr 12;52(6):3011-3030
SARS-CoV-2 variants evolve convergent strategies to remodel the host response.
Bouhaddou M, Reuschl AK, Polacco BJ, Thorne LG, Ummadi MR, Ye C, Rosales R, Pelin A, Batra J, Jang GM, Xu J, Moen JM, Richards AL, Zhou Y, Harjai B, Stevenson E, Rojc A, Ragazzini R, Whelan MVX, Furnon W, De Lorenzo G, Cowton V, Syed AM, Ciling A, Deutsch N, Pirak D, Dowgier G, Mesner D, Turner JL, McGovern BL, Rodriguez ML, Leiva-Rebollo R, Dunham AS, Zhong X, Eckhardt M, Fossati A, Liotta NF, Kehrer T, Cupic A, Rutkowska M, Mena I, Aslam S, Hoffert A, Foussard H, Olwal CO, Huang W, Zwaka T, Pham J, Lyons M, Donohue L, Griffin A, Nugent R, Holden K, Deans R, Aviles P, Lopez-Martin JA, Jimeno JM, Obernier K, Fabius JM, Soucheray M, Hüttenhain R, Jungreis I, Kellis M, Echeverria I, Verba K, Bonfanti P, Beltrao P, Sharan R, Doudna JA, Martinez-Sobrido L, Patel AH, Palmarini M, Miorin L, White K, Swaney DL, Garcia-Sastre A, Jolly C, Zuliani-Alvarez L, Towers GJ, Krogan NJ
Cell 2023 Oct 12;186(21):4597-4614.e26
Cell 2023 Oct 12;186(21):4597-4614.e26
CDK12 and Integrator-PP2A complex modulates LEO1 phosphorylation for processive transcription elongation.
Qiu M, Yin Z, Wang H, Lei L, Li C, Cui Y, Dai R, Yang P, Xiang Y, Li Q, Lv J, Hu Z, Chen M, Zhou HB, Fang P, Xiao R, Liang K
Science advances 2023 May 19;9(20):eadf8698
Science advances 2023 May 19;9(20):eadf8698
Identification of PDCD2 as a Candidate Target of Andrographolide That Arrests the Tumor Cell Cycle by Human Proteome-Scale Screening.
Wang L, Li C, Chen P, Liu C, Cui Z, Deng S, Yang H
ACS pharmacology & translational science 2022 Jul 8;5(7):479-490
ACS pharmacology & translational science 2022 Jul 8;5(7):479-490
Phase separation and toxicity of C9orf72 poly(PR) depends on alternate distribution of arginine.
Chen C, Yamanaka Y, Ueda K, Li P, Miyagi T, Harada Y, Tezuka S, Narumi S, Sugimoto M, Kuroda M, Hayamizu Y, Kanekura K
The Journal of cell biology 2021 Nov 1;220(11)
The Journal of cell biology 2021 Nov 1;220(11)
Novel role of PAF1 in attenuating radiosensitivity in cervical cancer by inhibiting IER5 transcription.
Zheng JJ, He Y, Liu Y, Li FS, Cui Z, Du XM, Wang CP, Wu YM
Radiation oncology (London, England) 2020 May 29;15(1):131
Radiation oncology (London, England) 2020 May 29;15(1):131
The Paf1 complex transcriptionally regulates the mitochondrial-anchored protein Atg32 leading to activation of mitophagy.
Zheng L, Shu WJ, Li YM, Mari M, Yan C, Wang D, Yin ZH, Jiang W, Zhou Y, Okamoto K, Reggiori F, Klionsky DJ, Song Z, Du HN
Autophagy 2020 Aug;16(8):1366-1379
Autophagy 2020 Aug;16(8):1366-1379
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 15441-1-AP(PAF1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-PAF1 (IP:15441-1-AP, 3ug; Detection:15441-1-AP 1:1000) with HeLa cells lysate 3000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human ovary tumor using 15441-1-AP(PAF1 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The PAF1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human PAF1. This antibody recognizes human antigen. The PAF1 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
