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LearnABIN500234
antibody from antibodies-online
Targeting: MARCHF8
c-MIR, CMIR, MARCH-VIII, MARCH8, MIR, RNF178
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- ABIN500234 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Membrane-Associated Ring Finger (C3HC4) 8, E3 Ubiquitin Protein Ligase (MARCH8) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- MARCH8 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human MARCH8.
- Description
- Peptide affinity chromatography
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 0.1 mg
- Storage
- Store at 2 - 8°C for up to one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references A novel family of membrane-bound E3 ubiquitin ligases.
Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.
c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity.
A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition.
Ohmura-Hoshino M, Goto E, Matsuki Y, Aoki M, Mito M, Uematsu M, Hotta H, Ishido S
Journal of biochemistry 2006 Aug;140(2):147-54
Journal of biochemistry 2006 Aug;140(2):147-54
Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins.
Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Früh K
Journal of virology 2004 Feb;78(3):1109-20
Journal of virology 2004 Feb;78(3):1109-20
c-MIR, a human E3 ubiquitin ligase, is a functional homolog of herpesvirus proteins MIR1 and MIR2 and has similar activity.
Goto E, Ishido S, Sato Y, Ohgimoto S, Ohgimoto K, Nagano-Fujii M, Hotta H
The Journal of biological chemistry 2003 Apr 25;278(17):14657-68
The Journal of biological chemistry 2003 Apr 25;278(17):14657-68
A novel class of herpesvirus-encoded membrane-bound E3 ubiquitin ligases regulates endocytosis of proteins involved in immune recognition.
Coscoy L, Sanchez DJ, Ganem D
The Journal of cell biology 2001 Dec 24;155(7):1265-73
The Journal of cell biology 2001 Dec 24;155(7):1265-73
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Western blot analysis of MARCH8 in HeLa cell lysate with AP30538PU-N at (A) 0.5 μg/ml and (B) 1 ?g/ml.
Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- Immunocytochemistry of MARCH8 in HeLa cells with AP30538PU-N at 2.5 ?g/ml.
