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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- PAB2933 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB2933, RRID:AB_1574531
- Product name
- DYRK1B polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of DYRK1B.
- Storage
- Store at 4°C. For long term storage store at -20°C.Aliquot to avoid repeated freezing and thawing.
Submitted references Mirk protein kinase is activated by MKK3 and functions as a transcriptional activator of HNF1alpha.
The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase.
Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells.
Lim S, Jin K, Friedman E
The Journal of biological chemistry 2002 Jul 12;277(28):25040-6
The Journal of biological chemistry 2002 Jul 12;277(28):25040-6
The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase.
Lim S, Zou Y, Friedman E
The Journal of biological chemistry 2002 Dec 20;277(51):49438-45
The Journal of biological chemistry 2002 Dec 20;277(51):49438-45
Mirk protein kinase is a mitogen-activated protein kinase substrate that mediates survival of colon cancer cells.
Lee K, Deng X, Friedman E
Cancer research 2000 Jul 1;60(13):3631-7
Cancer research 2000 Jul 1;60(13):3631-7
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Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Western blot analysis of DYRK1B polyclonal antibody (Cat # PAB2933) in mouse kidney tissue lysate. DYRK1B (Arrow) was detected using purified polyclonal antibody. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
Supportive validation
- Submitted by
- Abnova Corporation (provider)
- Main image
- Experimental details
- Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted with DYRK1B polyclonal antibody (Cat # PAB2933) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. HC = hepatocarcinoma.
- Validation comment
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
