Explore
Validate
LearnHPA014447
antibody from Atlas Antibodies
Targeting: PRRT2
DKFZp547J199, DSPB3, DYT10, EKD1, FICCA, FLJ25513, ICCA, IFITMD1, PKC
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- HPA014447 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA014447, RRID:AB_1855786
- Product name
- Anti-PRRT2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human PRRT2, Gene description: proline-rich transmembrane protein 2, Alternative Gene Names: DKFZp547J199, FICCA, FLJ25513, ICCA, IFITMD1, Validated applications: IHC, Uniprot ID: Q7Z6L0, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Rescue of neuropsychiatric phenotypes in a mouse model of 16p11.2 duplication syndrome by genetic correction of an epilepsy network hub
Proline‐rich transmembrane protein 2 specifically binds to GluA1 but has no effect on AMPA receptor‐mediated synaptic transmission
PRRT2 modulates presynaptic Ca2+ influx by interacting with P/Q-type channels
An Emerging Role of PRRT2 in Regulating Growth Cone Morphology
Presynaptic PRRT2 Deficiency Causes Cerebellar Dysfunction and Paroxysmal Kinesigenic Dyskinesia
Forrest M, Dos Santos M, Piguel N, Wang Y, Hawkins N, Bagchi V, Dionisio L, Yoon S, Simkin D, Martin-de-Saavedra M, Gao R, Horan K, George A, LeDoux M, Kearney J, Savas J, Penzes P
Nature Communications 2023;14(1)
Nature Communications 2023;14(1)
Proline‐rich transmembrane protein 2 specifically binds to GluA1 but has no effect on AMPA receptor‐mediated synaptic transmission
Feng H, Qiao F, Tan J, Zhang X, Hu P, Shi Y, Xu Z
Journal of Clinical Laboratory Analysis 2022;36(2)
Journal of Clinical Laboratory Analysis 2022;36(2)
PRRT2 modulates presynaptic Ca2+ influx by interacting with P/Q-type channels
Ferrante D, Sterlini B, Prestigio C, Marte A, Corradi A, Onofri F, Tortarolo G, Vicidomini G, Petretto A, Muià J, Thalhammer A, Valente P, Cingolani L, Benfenati F, Baldelli P
Cell Reports 2021;35(11):109248
Cell Reports 2021;35(11):109248
An Emerging Role of PRRT2 in Regulating Growth Cone Morphology
Savino E, Guarnieri F, Tsai J, Corradi A, Benfenati F, Valtorta F
Cells 2021;10(10):2666
Cells 2021;10(10):2666
Presynaptic PRRT2 Deficiency Causes Cerebellar Dysfunction and Paroxysmal Kinesigenic Dyskinesia
Calame D, Xiao J, Khan M, Hollingsworth T, Xue Y, Person A, LeDoux M
Neuroscience 2020;448
Neuroscience 2020;448
No comments: Submit comment
Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human cerebral cortex and pancreas tissues using HPA014447 antibody. Corresponding PRRT2 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
