CYP3A43

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein has a low level of testosterone hydroxylase activity, and may play a role in aging mechanisms and cancer progression. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Alternate splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

Description

Cytochrome P450 family 3 subfamily A member 43

Tissue specificity

Tissue enriched (liver)

Subcell location

Vesicles, Cytosol

Predicted location

Intracellular, Membrane

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Plasma proteins
Predicted intracellular proteins
Predicted membrane proteins

Chromosome

7 (99828013 - 99866102)

Ensembl ID

ENSG00000021461  (ver. 103.38)

Orthologs

-

UniProt

Q9HB55

neXtProt

NX_Q9HB55

Human splice variants

Protein structure