ABIN393663

antibody from antibodies-online

Targeting: VRK2

Provider product page for ABIN393663

Western blot

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [5]
Comments [0]
Validations
Western blot [4]
ELISA [1]

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Product number: ABIN393663 - Provider product page
Provider: antibodies-online
Product name: anti-Vaccinia Related Kinase 2 (VRK2) (AA 260-360) antibody
Antibody type: Monoclonal
Description: This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Reactivity: Human
Host: Mouse
Epitope: AA 260-360
Isotype: IgG
Antibody clone number: 3B10
Vial size: 100 μg
Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles

VRK2 protein structure - ABIN393663 shown in red.

Submitted references Common variants conferring risk of schizophrenia.

Stefansson H, Ophoff RA, Steinberg S, Andreassen OA, Cichon S, Rujescu D, Werge T, Pietiläinen OP, Mors O, Mortensen PB, Sigurdsson E, Gustafsson O, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Suvisaari J, Lonnqvist J, Paunio T, Børglum AD, Hartmann A, Fink-Jensen A, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Böttcher Y, Olesen J, Breuer R, Möller HJ, Giegling I, Rasmussen HB, Timm S, Mattheisen M, Bitter I, Réthelyi JM, Magnusdottir BB, Sigmundsson T, Olason P, Masson G, Gulcher JR, Haraldsson M, Fossdal R, Thorgeirsson TE, Thorsteinsdottir U, Ruggeri M, Tosato S, Franke B, Strengman E, Kiemeney LA, Genetic Risk and Outcome in Psychosis (GROUP)., Melle I, Djurovic S, Abramova L, Kaleda V, Sanjuan J, de Frutos R, Bramon E, Vassos E, Fraser G, Ettinger U, Picchioni M, Walker N, Toulopoulou T, Need AC, Ge D, Yoon JL, Shianna KV, Freimer NB, Cantor RM, Murray R, Kong A, Golimbet V, Carracedo A, Arango C, Costas J, Jönsson EG, Terenius L, Agartz I, Petursson H, Nöthen MM, Rietschel M, Matthews PM, Muglia P, Peltonen L, St Clair D, Goldstein DB, Stefansson K, Collier DA
Nature 2009 Aug 6;460(7256):744-7

Proteomics identification of nuclear Ran GTPase as an inhibitor of human VRK1 and VRK2 (vaccinia-related kinase) activities.

Sanz-García M, López-Sánchez I, Lazo PA
Molecular & cellular proteomics : MCP 2008 Nov;7(11):2199-214

The C/H3 domain of p300 is required to protect VRK1 and VRK2 from their downregulation induced by p53.

Valbuena A, Blanco S, Vega FM, Lazo PA
PloS one 2008 Jul 9;3(7):e2649

Modulation of interleukin-1 transcriptional response by the interaction between VRK2 and the JIP1 scaffold protein.

Blanco S, Sanz-García M, Santos CR, Lazo PA
PloS one 2008 Feb 20;3(2):e1660

Blanco S, Santos C, Lazo PA
Molecular and cellular biology 2007 Oct;27(20):7273-83