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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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- Product number
- PA5-57768 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- FANCL Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full-length protein
- Description
- Immunogen sequence: ALKNRQELYA LPPPPQFYSS LIEEIGTLGW DKLVYADTCF STIKLKAEDA SGREHLITLK LKAKYPAESP DYFVDFPVPF C Highest antigen sequence identity to the following orthologs: Mouse - 65%, Rat - 67%.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.2 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia.
Shen X, Wang R, Kim MJ, Hu Q, Hsu CC, Yao J, Klages-Mundt N, Tian Y, Lynn E, Brewer TF, Zhang Y, Arun B, Gan B, Andreeff M, Takeda S, Chen J, Park JI, Shi X, Chang CJ, Jung SY, Qin J, Li L
Molecular cell 2020 Dec 17;80(6):1013-1024.e6
Molecular cell 2020 Dec 17;80(6):1013-1024.e6
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Western blot analysis of FANCL in human cell line NTERA-2 using a FANCL Polyclonal Antibody (Product # PA5-57768).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of FANCL in human cell line U-2 OS using a FANCL Polyclonal Antibody (Product # PA5-57768) shows localization to nuclear bodies and vesicles.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical staining of FANCL in human duodenum using a FANCL Polyclonal Antibody (Product # PA5-57768) shows strong cytoplasmic positivity in glandular cells.
