Antibody data
- Antibody Data
- Antigen structure
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- Product number
- orb150849 - Provider product page
- Provider
- Biorbyt
- Product name
- LGI1 Antibody: Biotin
- Antibody type
- Monoclonal
- Description
- Mouse monoclonal to LGI1 (Biotin). The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist; this LGI1 antibody will recognize only the longer form..
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Biotin
- Isotype
- IgG
- Antibody clone number
- N283/7 (Formerly sold as S283-7)
- Vial size
- 100 ug
- Concentration
- 1 mg/ml
- Storage
- Conjugated antibodies should be stored according to the product label
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