orb150849

antibody from Biorbyt
Targeting: LGI1 EPITEMPIN, EPT, ETL1, IB1099
Provider product page for orb150849
Western blot
ELISA
Immunocytochemistry
Immunohistochemistry

Antibody data

Product number
orb150849 - Provider product page
Provider
Biorbyt
Product name
LGI1 Antibody: Biotin
Antibody type
Monoclonal
Description
Mouse monoclonal to LGI1 (Biotin). The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as a candidate tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are highly similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. Two isoforms of LGI1 are known to exist; this LGI1 antibody will recognize only the longer form..
Reactivity
Human, Mouse, Rat
Host
Mouse
Conjugate
Biotin
Isotype
IgG
Antibody clone number
N283/7 (Formerly sold as S283-7)
Vial size
100 ug
Concentration
1 mg/ml
Storage
Conjugated antibodies should be stored according to the product label
LGI1 protein structure - orb150849 shown in red.