12640-1-AP

antibody from Proteintech Group

Targeting: GOLGA1 golgin-97, MGC33154

Provider product page for 12640-1-AP

Western blot

ELISA

Immunocytochemistry

Immunoprecipitation

Antibody data

Antibody Data
Antigen structure
References [38]
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Validations
Western blot [1]

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Product number: 12640-1-AP - Provider product page
Provider: Proteintech Group
Proper citation: Proteintech Cat#12640-1-AP, RRID:AB_2115315
Product name: golgin 97 antibody
Antibody type: Polyclonal
Description: golgin 97 antibody (Cat. #12640-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB, ELISA.
Reactivity: Human, Mouse
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

GOLGA1 protein structure - 12640-1-AP shown in red.

Submitted references Negative feedback regulation of STING signaling by TAX1BP1-directed Golgiphagy.

Suklabaidya S, Mohanty S, Reider IE, White J, Colter D, McCormick SM, Shembade N, Choi YB, Norbury CC, Harhaj EW
Nature communications 2026 Feb 11;17(1)

Fluzoparib disrupts Golgi apparatus to inhibit O-GlcNAcylation and nuclear translocation of β-catenin to attenuate ovarian cancer invasion and metastasis.

Peng J, Liu J, Ning M, Han W, Wang H, Wang Z, Hong L, Liu C
International immunopharmacology 2025 Sep 23;162:115158

Proinflammatory Cytokines Mediate Pancreatic β-Cell-Specific Alterations to Golgi Integrity via iNOS-Dependent Mitochondrial Inhibition.

Blom SE, Narsian PR, Behan-Bush RM, Ankrum JA, Yang L, Stephens SB
Diabetes 2025 Nov 1;74(11):1992-2007

Aggregated proinsulin in pancreatic β-cells is degraded by the autophagy pathway.

Madey YF, Syed SK, Van Horn RD, Pineros AR, Efanov AM
The Journal of biological chemistry 2025 Mar;301(3):108257

The use of adeno-associated vírus-based gene therapy to achieve long-term expression of recombinant neutralizing antibody against ricin.

Yu K, Sun C, Dong M, Song S, Wang Y, Zhao N, Xu N, Liu W
Toxicon : official journal of the International Society on Toxinology 2025 Mar;256:108289

Trans-Golgi network tethering factors regulate TBK1 trafficking and promote the STING-IFN-I pathway.

Wang J, Niu S, Hu X, Li T, Liu S, Tu Y, Shang Z, Zhao L, Xu P, Lin J, Chen L, Billadeau DD, Jia D
Cell discovery 2025 Mar 18;11(1):23

EndoMAP.v1 charts the structural landscape of human early endosome complexes.

Gonzalez-Lozano MA, Schmid EW, Miguel Whelan E, Jiang Y, Paulo JA, Walter JC, Harper JW
Nature 2025 Jul;643(8070):252-261

TUG protein acts through a disordered region to organize the early secretory pathway.

Parchure A, Tejada H, Xi Z, Kim Y, Su M, Yan Y, Julca-Zevallos O, Alcázar-Román AR, Villemeur M, Liu X, Toomre D, Raote I, Bogan JS
Nature communications 2025 Jul 1;16(1):5518

Proinflammatory cytokines mediate pancreatic β-cell specific alterations to Golgi morphology via iNOS-dependent mitochondrial inhibition.

Blom SE, Behan-Bush RM, Ankrum JA, Yang L, Stephens SB
bioRxiv : the preprint server for biology 2025 Jan 29;

EndoMAP.v1, a Structural Protein Complex Landscape of Human Endosomes.

Gonzalez-Lozano MA, Schmid EW, Whelan EM, Jiang Y, Paulo JA, Walter JC, Harper JW
bioRxiv : the preprint server for biology 2025 Feb 9;

Aberrant expression of GTPase-activating protein ARAP1 triggers circular dorsal ruffles associated with malignancy in hepatocellular carcinoma Hep3B cells.

Sun X, Li Y, He Y, Cheng L, Wang L, Wei J, Chen J, Du L, Shen Z, Xie Y, Midgley AC, Jiang W, Yoshida S
Cell communication and signaling : CCS 2025 Feb 11;23(1):75

Involvement of sphingosine 1-phosphate signaling in insulin-like growth factor-II/mannose 6-phosphate receptor trafficking from endosome to the trans-Golgi network.

Nishida S, Matovelo SA, Kajimoto T, Nakamura SI, Okada T
Communications biology 2024 Sep 19;7(1):1182

SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation.

Dias AP, Rehmani T, Applin BD, Salih M, Tuana B
Open biology 2024 Oct;14(10):rsob240206

Tail-anchored membrane protein SLMAP3 is essential for targeting centrosomal proteins to the nuclear envelope in skeletal myogenesis.

Dias AP, Rehmani T, Salih M, Tuana B
Open biology 2024 Oct;14(10):240094

Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways.

Quirion L, Robert A, Boulais J, Huang S, Bernal Astrain G, Strakhova R, Jo CH, Kherdjemil Y, Faubert D, Thibault MP, Kmita M, Baskin JM, Gingras AC, Smith MJ, Côté JF
Journal of cell science 2024 May 1;137(9)

Extracellular α-synuclein impairs sphingosine 1-phosphate receptor type 3 (S1PR3)-regulated lysosomal delivery of cathepsin D in HeLa cells.

Nishida S, Matovelo SA, Kajimoto T, Nakamura SI, Okada T
Genes to cells : devoted to molecular & cellular mechanisms 2024 Mar;29(3):207-216

Mapping the global interactome of the ARF family reveals spatial organization in cellular signaling pathways.

Quirion L, Robert A, Boulais J, Huang S, Bernal Astrain G, Strakhova R, Jo CH, Kherdjemil Y, Thibault MP, Faubert D, Kmita M, Baskin JM, Gingras AC, Smith MJ, Cote JF
bioRxiv : the preprint server for biology 2024 Mar 25;

SARS-CoV-2 remodels the Golgi apparatus to facilitate viral assembly and secretion.

Zhang J, Kennedy A, de Melo Jorge DM, Xing L, Reid W, Bui S, Joppich J, Rose M, Ercan S, Tang Q, Tai AW, Wang Y
bioRxiv : the preprint server for biology 2024 Mar 15;

Loss of the Golgi-localized v-ATPase subunit does not alter insulin granule formation or pancreatic islet β-cell function.

Boyer CK, Blom SE, Machado AE, Rohli KE, Maxson ME, Stephens SB
American journal of physiology. Endocrinology and metabolism 2024 Mar 1;326(3):E245-E257

A conserved ion channel function of STING mediates noncanonical autophagy and cell death.

Xun J, Zhang Z, Lv B, Lu D, Yang H, Shang G, Tan JX
EMBO reports 2024 Feb;25(2):544-569

TBC1D23 mediates Golgi-specific LKB1 signaling.

Tu Y, Yang Q, Tang M, Gao L, Wang Y, Wang J, Liu Z, Li X, Mao L, Jia RZ, Wang Y, Tang TS, Xu P, Liu Y, Dai L, Jia D
Nature communications 2024 Feb 27;15(1):1785

The WDR11 complex is a receptor for acidic-cluster-containing cargo proteins.

Deng H, Jia G, Li P, Tang Y, Zhao L, Yang Q, Zhao J, Wang J, Tu Y, Yong X, Zhang S, Mo X, Billadeau DD, Su Z, Jia D
Cell 2024 Aug 8;187(16):4272-4288.e20

Morphological determination of localization and function of Golgi proteins.

Xing Y, Jian Y, Zhao X, Zhang Y, Zhang Z, Zhang X, Zhang X
Biophysics reports 2024 Apr 30;10(2):121-132

Common Markers and Small Molecule Inhibitors in Golgi Studies.

Bui S, Stark D, Li J, Zhang J, Wang Y
Methods in molecular biology (Clifton, N.J.) 2023;2557:453-493

Immunofluorescence Microscopy of the Mammalian Golgi Apparatus.

Arab M, Nayak SC, Vitali T, Lowe M
Methods in molecular biology (Clifton, N.J.) 2023;2557:101-111

Anti-ricin toxin human neutralizing antibodies and DMAbs protection against ricin toxin poisoning.

Yu H, Wu M, Zhao N, Dong M, Wang Y, Yu K, Sun C, Xu N, Ge L, Liu W
Toxicology letters 2023 Jul 1;383:152-161

CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth.

Yin S, Liu L, Ball LE, Wang Y, Bedford MT, Duncan SA, Wang H, Gan W
Cell reports 2023 Apr 25;42(4):112316

Potential mechanisms of osthole against bladder cancer cells based on network pharmacology, molecular docking, and experimental validation.

Jiang Y, Zhang M, Wang L, Zhang L, Ma M, Jing M, Li J, Song R, Zhang Y, Yang Z, Zhang Y, Pu Y, Qu X, Fan J
BMC complementary medicine and therapies 2023 Apr 17;23(1):122

Selenoprotein K contributes to CD36 subcellular trafficking in hepatocytes by accelerating nascent COPII vesicle formation and aggravates hepatic steatosis.

You M, Wu F, Gao M, Chen M, Zeng S, Zhang Y, Zhao W, Li D, Wei L, Ruan XZ, Chen Y
Redox biology 2022 Nov;57:102500

CD36 promotes de novo lipogenesis in hepatocytes through INSIG2-dependent SREBP1 processing.

Zeng H, Qin H, Liao M, Zheng E, Luo X, Xiao A, Li Y, Chen L, Wei L, Zhao L, Ruan XZ, Yang P, Chen Y
Molecular metabolism 2022 Mar;57:101428

Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6.

Qiu N, Abegg D, Guidi M, Gilmore K, Seeberger PH, Adibekian A
Cell chemical biology 2022 Mar 17;29(3):530-537.e7

Depletion of mitochondrial methionine adenosyltransferase α1 triggers mitochondrial dysfunction in alcohol-associated liver disease.

Barbier-Torres L, Murray B, Yang JW, Wang J, Matsuda M, Robinson A, Binek A, Fan W, Fernández-Ramos D, Lopitz-Otsoa F, Luque-Urbano M, Millet O, Mavila N, Peng H, Ramani K, Gottlieb R, Sun Z, Liangpunsakul S, Seki E, Van Eyk JE, Mato JM, Lu SC
Nature communications 2022 Jan 28;13(1):557

The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic.

Turn RE, Hu Y, Dewees SI, Devi N, East MP, Hardin KR, Khatib T, Linnert J, Wolfrum U, Lim MJ, Casanova JE, Caspary T, Kahn RA
Molecular biology of the cell 2022 Feb 1;33(2):ar13

GRASP55 regulates the unconventional secretion and aggregation of mutant huntingtin.

Ahat E, Bui S, Zhang J, da Veiga Leprevost F, Sharkey L, Reid W, Nesvizhskii AI, Paulson HL, Wang Y
The Journal of biological chemistry 2022 Aug;298(8):102219

Nondegradable ubiquitinated ATG9A organizes Golgi integrity and dynamics upon stresses.

Luo Q, Liu Q, Cheng H, Wang J, Zhao T, Zhang J, Mu C, Meng Y, Chen L, Zhou C, Lei H, Yang J, Chen G, Li Y, Pan L, Chen Q, Zhu Y
Cell reports 2022 Aug 16;40(7):111195

Endocytic recycling as cellular trafficking fate of simvastatin-loaded discoidal reconstituted high-density lipoprotein to coordinate cholesterol efflux and drug influx.

Qi Z, Jiang C, Gao H, Wang Y, Zhang Q, Zhang W, Liu J
Nanomedicine : nanotechnology, biology, and medicine 2021 Feb;32:102323

Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress.

Merriman C, Fu D
The Journal of biological chemistry 2019 Nov 8;294(45):16992-17006

GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion.

Zhang X, Wang L, Lak B, Li J, Jokitalo E, Wang Y
Developmental cell 2018 Apr 23;45(2):245-261.e6

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Supportive validation

Submitted by: Proteintech Group (provider)
Main image
Experimental details: The golgin 97 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human golgin 97. This antibody recognizes human,mouse,rat antigen. The golgin 97 antibody has been validated for the following applications: ELISA, WB analysis.
Appendix: 12640-1-AP.pdf

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