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- Antibody Data
- Antigen structure
- References [138]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 10749-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10749-1-AP, RRID:AB_2285104
- Product name
- RHOA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RHOA antibody (Cat. #10749-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Human Placental Mesenchymal Stem Cells-Exosomes Alleviate Endothelial Barrier Dysfunction via Cytoskeletal Remodeling through hsa-miR-148a-3p/ROCK1 Pathway.
Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury.
Resolvin D1 attenuates Ang II-induced hypertension in mice by inhibiting the proliferation, migration and phenotypic transformation of vascular smooth muscle cells by blocking the RhoA/mitogen-activated protein kinase pathway.
P75(NTR+)CD64(+) neutrophils promote sepsis-induced acute lung injury.
Urotensin II receptor deficiency ameliorates ligation-induced carotid intimal hyperplasia partially through the RhoA-YAP1 pathway.
Therapeutic potential of Lingjiao Gouteng decoction in acute alcohol intoxication and alcohol-induced brain injury involving the RhoA/ROCK2/NF-κB signaling pathway.
Activation of cell adhesion and migration is an early event of platelet-rich plasma (PRP)-dependent stimulation of human adipose-derived stem/stromal cells.
Scinderin promotes glioma cell migration and invasion via remodeling actin cytoskeleton.
Cortactin is in a complex with VE-cadherin and is required for endothelial adherens junction stability through Rap1/Rac1 activation.
Silencing geranylgeranyltransferase I inhibits the migration and invasion of salivary adenoid cystic carcinoma through RhoA/ROCK1/MLC signaling and suppresses proliferation through cell cycle regulation.
PIEZO1 regulates leader cell formation and cellular coordination during collective keratinocyte migration.
FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation.
Ellagic acid alleviates TNBS-induced intestinal barrier dysfunction by regulating mucin secretion and maintaining tight junction integrity in rats.
Dahuang-Taoren, a botanical drug combination, ameliorates adenomyosis via inhibiting Rho GTPases.
Mechanical stimulation promotes MSCs healing the lesion of intervertebral disc annulus fibrosus.
Sonic Hedgehog Signaling Is Essential for Pulmonary Ionocyte Specification in Human and Ferret Airway Epithelia.
TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor.
Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.
Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease.
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Stress stimulation maintaining by genipin crosslinked hydrogel promotes annulus fibrosus healing.
Xinfuli granule alleviates metabolic remodeling through inhibition of endoplasmic reticulum stress and mitochondrial injury in heart failure.
Downregulation of HAS‑2 regulates the chondrocyte cytoskeleton and induces cartilage degeneration by activating the RhoA/ROCK signaling pathway.
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
The Helicobacter pylori CagA oncoprotein disrupts Wnt/PCP signaling and promotes hyperproliferation of pyloric gland base cells.
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Human Umbilical Cord Mesenchymal Stem Cells Improve the Status of Hypoxic/Ischemic Cerebral Palsy Rats by Downregulating NogoA/NgR/Rho Pathway.
Adipose-derived stem cells with miR-150-5p inhibition laden in hydroxyapatite/tricalcium phosphate ceramic powders promote osteogenesis via regulating Notch3 and activating FAK/ERK and RhoA.
Reducing GEF-H1 Expression Inhibits Renal Cyst Formation, Inflammation, and Fibrosis via RhoA Signaling in Nephronophthisis.
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
Nose-to-brain translocation and nervous system injury in response to indium tin oxide nanoparticles of long-term low-dose exposures.
Biodegradable nano black phosphorus based SDF1-α delivery system ameliorates Erectile Dysfunction in a cavernous nerve injury rat model by recruiting endogenous stem/progenitor cells.
Growth differentiation factor 5 inhibits lipopolysaccharide-mediated pyroptosis of nucleus pulposus mesenchymal stem cells via RhoA signaling pathway.
Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function.
The Inhibitory Effect of RADKPS on Pyroptosis of Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Rosmarinic acid alleviates intestinal inflammatory damage and inhibits endoplasmic reticulum stress and smooth muscle contraction abnormalities in intestinal tissues by regulating gut microbiota.
Inhibition of Cxcr4 Disrupts Mouse Embryonic Palatal Mesenchymal Cell Migration and Induces Cleft Palate Occurrence.
Smurf1 regulates ameloblast polarization by ubiquitination-mediated degradation of RhoA.
Tetrandrine Attenuates Podocyte Injury by Inhibiting TRPC6-Mediated RhoA/ROCK1 Pathway.
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.
The role of activated androgen receptor in cofilin phospho-regulation depends on the molecular subtype of TNBC cell line and actin assembly dynamics.
Effects of Shenkang Pills on Early-Stage Diabetic Nephropathy in db/db Mice via Inhibiting AURKB/RacGAP1/RhoA Signaling Pathway.
Cellular mechanism of action of forsythiaside for the treatment of diabetic kidney disease.
Signaling Proteins Recruited to the Sperm Binding Site: Role of β-Catenin and Rho A.
eIF3a Regulates Colorectal Cancer Metastasis via Translational Activation of RhoA and Cdc42.
Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism.
Study of differential proteomics in granulosa cells of premature ovarian insufficiency (POI) and the roles and mechanism of RAC1 in granulosa cells.
Laminin-511 Activates the Human Induced Pluripotent Stem Cell Survival via α6β1 Integrin-Fyn-RhoA-ROCK Signaling.
CHIR99021 balance TGFβ1 induced human corneal endothelial-to-mesenchymal transition to favor corneal endothelial cell proliferation.
Damnacanthal isolated from morinda species inhibited ovarian cancer cell proliferation and migration through activating autophagy.
Circadian nuclear receptor Rev-erbα is expressed by platelets and potentiates platelet activation and thrombus formation.
Non-canonical Wnt/calcium signaling is protective against podocyte injury and glomerulosclerosis.
Acetyl-L-carnitine improves erectile function in bilateral cavernous nerve injury rats via promoting cavernous nerve regeneration.
Glycomics reveal that ST6GAL1-mediated sialylation regulates uterine lumen closure during implantation.
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.
Klotho functionalization on vascular graft for improved patency and endothelialization.
Berberine Depresses Inflammation and Adjusts Smooth Muscle to Ameliorate Ulcerative Colitis of Cats by Regulating Gut Microbiota.
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
Dematin inhibits glioblastoma malignancy through RhoA-mediated CDKs downregulation and cytoskeleton remodeling.
Echinococcus multilocularis drives the polarization of macrophages by regulating the RhoA-MAPK signaling pathway and thus affects liver fibrosis.
Src-IL-18 signaling regulates the secretion of atrial natriuretic factor in hypoxic beating rat atria.
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
The association of transcription factor Prox1 with the proliferation, migration, and invasion of lung cancer.
PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease.
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection.
Regulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β-catenin signalling via interaction with Gli1.
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Circ-NOLC1 promotes epithelial ovarian cancer tumorigenesis and progression by binding ESRP1 and modulating CDK1 and RhoA expression.
CircARHGAP12 promotes nasopharyngeal carcinoma migration and invasion via ezrin-mediated cytoskeletal remodeling.
m(6)A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.
Therapeutic Hypothermia Mitigates the Sepsis-Increased Permeability in EA. hy926 Cells by Preserving Rap1 Expression.
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
Hsa_circ_001659 serves as a novel diagnostic and prognostic biomarker for colorectal cancer.
Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.
Icariin Alleviates Glucocorticoid-Induced Osteoporosis through EphB4/Ephrin-B2 Axis.
Tetrandrine Suppresses Transient Receptor Potential Cation Channel Protein 6 Overexpression- Induced Podocyte Damage via Blockage of RhoA/ROCK1 Signaling.
Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling.
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus.
CEACAM6 promotes cisplatin resistance in lung adenocarcinoma and is regulated by microRNA-146a and microRNA-26a.
The Role of ROCK in Platelet-Monocyte Collaborative Induction of Thromboinflammation during Acute Coronary Syndrome.
Chronic inflammation promotes proliferation in the prostatic stroma in rats with experimental autoimmune prostatitis: study for a novel method of inducing benign prostatic hyperplasia in a rat model.
JTE-013 supplementation improves erectile dysfunction in rats with streptozotocin-induced type Ⅰ diabetes through the inhibition of the rho-kinase pathway, fibrosis, and apoptosis.
LncRNA CTC-497E21.4 promotes the progression of gastric cancer via modulating miR-22/NET1 axis through RhoA signaling pathway.
Proto-Oncogene Serine/Threonine Kinase PIM3 Promotes Cell Migration via Modulating Rho GTPase Signaling.
Impact of RhoA overexpression on clinical outcomes in cervical squamous cell carcinoma treated with concurrent chemoradiotherapy.
A mosquito salivary protein promotes flavivirus transmission by activation of autophagy.
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
A DAAM1 3'-UTR SNP mutation regulates breast cancer metastasis through affecting miR-208a-5p-DAAM1-RhoA axis.
Effects of Dexmedetomidine on the RhoA /ROCK/ Nox4 Signaling Pathway in Renal Fibrosis of Diabetic Rats.
Wnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cells.
P2Y12 receptor mediates microglial activation via RhoA/ROCK pathway in the trigeminal nucleus caudalis in a mouse model of chronic migraine.
lncRNA 430945 promotes the proliferation and migration of vascular smooth muscle cells via the ROR2/RhoA signaling pathway in atherosclerosis.
Agenesis and Hypomyelination of Corpus Callosum in Mice Lacking Nsun5, an RNA Methyltransferase.
RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis.
Overexpression of Na(+)/H(+) exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK.
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex.
High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.
Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.
Androgen deficiency impairs erectile function in rats through promotion of corporal fibrosis.
Loss of SPRR3 in ApoE-/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs.
Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons.
FTY720 Supplementation Partially Improves Erectile Dysfunction in Rats With Streptozotocin-Induced Type 1 Diabetes Through Inhibition of Endothelial Dysfunction and Corporal Fibrosis.
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
Graphene Oxide Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents.
Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.
Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1.
MicroRNA-490 inhibits tumorigenesis and progression in breast cancer.
The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker.
AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.
Oligophrenin1 protects mice against myocardial ischemia and reperfusion injury by modulating inflammation and myocardial apoptosis.
Neurotrophic and neuroprotective properties of exendin-4 in adult rat dorsal root ganglion neurons: involvement of insulin and RhoA.
Inhibiting Rho kinase 2 reduces memory dysfunction in adult rats exposed to sevoflurane at postnatal days 7-9.
miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis.
Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Overexpression of RNF146 in non-small cell lung cancer enhances proliferation and invasion of tumors through the Wnt/β-catenin signaling pathway.
Baculovirus induces host cell aggregation via a Rho/Rok-dependent mechanism.
Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells.
iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.
Energy metabolism analysis reveals the mechanism of inhibition of breast cancer cell metastasis by PEG-modified graphene oxide nanosheets.
The Rho-kinase inhibitor fasudil restores normal motor nerve conduction velocity in diabetic rats by assuring the proper localization of adhesion-related molecules in myelinating Schwann cells.
Loss of p57 expression and RhoA overexpression are associated with poor survival of patients with hepatocellular carcinoma.
DEK depletion negatively regulates Rho/ROCK/MLC pathway in non-small cell lung cancer.
Isoform-specific roles of the GTPase activating protein Nadrin in cytoskeletal reorganization of platelets.
Toosendanin induces apoptosis through suppression of JNK signaling pathway in HL-60 cells.
Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling.
Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.
Downregulation of p57 accelerates the growth and invasion of hepatocellular carcinoma.
Lv Y, Yu W, Xuan R, Yang Y, Xue X, Ma X
Stem cells international 2024;2024:2172632
Stem cells international 2024;2024:2172632
Mertk Reduces Blood-Spinal Cord Barrier Permeability Through the Rhoa/Rock1/P-MLC Pathway After Spinal Cord Injury.
Lin J, Sun Y, Xia B, Wang Y, Xie C, Wang J, Hu J, Zhu L
Neuroscience bulletin 2024 Sep;40(9):1230-1244
Neuroscience bulletin 2024 Sep;40(9):1230-1244
Resolvin D1 attenuates Ang II-induced hypertension in mice by inhibiting the proliferation, migration and phenotypic transformation of vascular smooth muscle cells by blocking the RhoA/mitogen-activated protein kinase pathway.
Wei C, Zhang J, Peng S, Liu J, Xu Y, Zhao M, Xu S, Pan W, Yin Z, Zheng Z, Qin JJ, Wan J, Wang M
Journal of hypertension 2024 Mar 1;42(3):420-431
Journal of hypertension 2024 Mar 1;42(3):420-431
P75(NTR+)CD64(+) neutrophils promote sepsis-induced acute lung injury.
Fu D, Gao S, Li JN, Cui YH, Luo YW, Zhong YJ, Li Q, Luo C, Dai RP, Luo RY, Hu ZL
Clinical immunology (Orlando, Fla.) 2024 Jun;263:110206
Clinical immunology (Orlando, Fla.) 2024 Jun;263:110206
Urotensin II receptor deficiency ameliorates ligation-induced carotid intimal hyperplasia partially through the RhoA-YAP1 pathway.
Wei P, Tian K, Liu H, Li K, Alam N, Cheng D, Li M, He X, Guo J, Wang R, Wang W, Bai L, Liu E, Xu B, Li Y, Zhao S
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167170
Biochimica et biophysica acta. Molecular basis of disease 2024 Jun;1870(5):167170
Therapeutic potential of Lingjiao Gouteng decoction in acute alcohol intoxication and alcohol-induced brain injury involving the RhoA/ROCK2/NF-κB signaling pathway.
Li J, Liu Y, Chen X, Luo M, Yin M, Xie X, Ai Y, Zhang X, He J
Journal of ethnopharmacology 2024 Jun 28;328:118114
Journal of ethnopharmacology 2024 Jun 28;328:118114
Activation of cell adhesion and migration is an early event of platelet-rich plasma (PRP)-dependent stimulation of human adipose-derived stem/stromal cells.
Fukui M, Lai F, Hihara M, Mitsui T, Matsuoka Y, Sun Z, Kunieda S, Taketani S, Odaka T, Okuma K, Kakudo N
Human cell 2024 Jan;37(1):181-192
Human cell 2024 Jan;37(1):181-192
Scinderin promotes glioma cell migration and invasion via remodeling actin cytoskeleton.
Lin X, Zhao Z, Sun SP, Liu W
World journal of clinical oncology 2024 Jan 24;15(1):32-44
World journal of clinical oncology 2024 Jan 24;15(1):32-44
Cortactin is in a complex with VE-cadherin and is required for endothelial adherens junction stability through Rap1/Rac1 activation.
Moztarzadeh S, Sepic S, Hamad I, Waschke J, Radeva MY, García-Ponce A
Scientific reports 2024 Jan 12;14(1):1218
Scientific reports 2024 Jan 12;14(1):1218
Silencing geranylgeranyltransferase I inhibits the migration and invasion of salivary adenoid cystic carcinoma through RhoA/ROCK1/MLC signaling and suppresses proliferation through cell cycle regulation.
Chi Z, Wang Q, Tong L, Qiu J, Yang F, Guo Q, Li W, Zheng J, Chen Z
Cell biology international 2024 Feb;48(2):174-189
Cell biology international 2024 Feb;48(2):174-189
PIEZO1 regulates leader cell formation and cellular coordination during collective keratinocyte migration.
Chen J, Holt JR, Evans EL, Lowengrub JS, Pathak MM
PLoS computational biology 2024 Apr;20(4):e1011855
PLoS computational biology 2024 Apr;20(4):e1011855
FBXL8 inhibits post-myocardial infarction cardiac fibrosis by targeting Snail1 for ubiquitin-proteasome degradation.
Li Y, Zuo C, Wu X, Ding Y, Wei Y, Chen S, Lu X, Xu J, Liu S, Zhou G, Cai L
Cell death & disease 2024 Apr 13;15(4):263
Cell death & disease 2024 Apr 13;15(4):263
Ellagic acid alleviates TNBS-induced intestinal barrier dysfunction by regulating mucin secretion and maintaining tight junction integrity in rats.
Peng B, Xue L, Yu Q, Zhong T
International journal of food sciences and nutrition 2023;74(4):476-486
International journal of food sciences and nutrition 2023;74(4):476-486
Dahuang-Taoren, a botanical drug combination, ameliorates adenomyosis via inhibiting Rho GTPases.
Lei Y, Fu X, Chen M, Yi Y, Mao P, Peng L, Qu Z
Frontiers in pharmacology 2023;14:1089004
Frontiers in pharmacology 2023;14:1089004
Mechanical stimulation promotes MSCs healing the lesion of intervertebral disc annulus fibrosus.
Deng R, Kang R, Jin X, Wang Z, Liu X, Wang Q, Xie L
Frontiers in bioengineering and biotechnology 2023;11:1137199
Frontiers in bioengineering and biotechnology 2023;11:1137199
Sonic Hedgehog Signaling Is Essential for Pulmonary Ionocyte Specification in Human and Ferret Airway Epithelia.
Cai Q, Luo M, Tang Y, Yu M, Yuan F, Gasser GN, Liu X, Engelhardt JF
American journal of respiratory cell and molecular biology 2023 Sep;69(3):295-309
American journal of respiratory cell and molecular biology 2023 Sep;69(3):295-309
TNF-α evokes blood-brain barrier dysfunction through activation of Rho-kinase and neurokinin 1 receptor.
Gao X, Bayraktutan U
Immunobiology 2023 Sep;228(5):152706
Immunobiology 2023 Sep;228(5):152706
Pleckstrin homology and RhoGEF domain containing G4 (PLEKHG4) leads to the activation of RhoGTPases promoting the malignant phenotypes of thyroid cancer.
Yuan Q, Fan Y, Liu Z, Wang X, Jia M, Dong Y, Geng Z, Zheng J, Lu X
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1315-1331
Apoptosis : an international journal on programmed cell death 2023 Oct;28(9-10):1315-1331
Soluble TREM2 ameliorates tau phosphorylation and cognitive deficits through activating transgelin-2 in Alzheimer's disease.
Zhang X, Tang L, Yang J, Meng L, Chen J, Zhou L, Wang J, Xiong M, Zhang Z
Nature communications 2023 Oct 21;14(1):6670
Nature communications 2023 Oct 21;14(1):6670
RUNX1 promotes proliferation and migration in non-small cell lung cancer cell lines via the mTOR pathway.
Ma H, Jiang S, Yuan Y, Li J, Li Y, Lv Y, Du T, Guan J, Jiang X, Tian L, Zheng Q, Yang L, Li Q
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2023 Nov;37(11):e23195
Stress stimulation maintaining by genipin crosslinked hydrogel promotes annulus fibrosus healing.
Wang Z, Jin X, Zhang B, Kong J, Deng R, Wu K, Xie L, Liu X, Kang R
Journal of orthopaedic translation 2023 May;40:104-115
Journal of orthopaedic translation 2023 May;40:104-115
Xinfuli granule alleviates metabolic remodeling through inhibition of endoplasmic reticulum stress and mitochondrial injury in heart failure.
Su YN, Lu PP, Yan SY, Guo XT, Ma J, Guo CX, Ma LH
Journal of ethnopharmacology 2023 Mar 1;303:115782
Journal of ethnopharmacology 2023 Mar 1;303:115782
Downregulation of HAS‑2 regulates the chondrocyte cytoskeleton and induces cartilage degeneration by activating the RhoA/ROCK signaling pathway.
Yang J, Wang L, Zhang Z, Sun Q, Zhang Y
International journal of molecular medicine 2023 Jul;52(1)
International journal of molecular medicine 2023 Jul;52(1)
The role of TOP2A in immunotherapy and vasculogenic mimicry in non-small cell lung cancer and its potential mechanism.
Wu J, Zhang L, Li W, Wang L, Jia Q, Shi F, Li K, Liao L, Shi Y, Wu S
Scientific reports 2023 Jul 5;13(1):10906
Scientific reports 2023 Jul 5;13(1):10906
The Helicobacter pylori CagA oncoprotein disrupts Wnt/PCP signaling and promotes hyperproliferation of pyloric gland base cells.
Takahashi-Kanemitsu A, Lu M, Knight CT, Yamamoto T, Hayashi T, Mii Y, Ooki T, Kikuchi I, Kikuchi A, Barker N, Susaki EA, Taira M, Hatakeyama M
Science signaling 2023 Jul 18;16(794):eabp9020
Science signaling 2023 Jul 18;16(794):eabp9020
PLAGL2 promotes bladder cancer progression via RACGAP1/RhoA GTPase/YAP1 signaling.
Chen H, Yang W, Li Y, Ji Z
Cell death & disease 2023 Jul 15;14(7):433
Cell death & disease 2023 Jul 15;14(7):433
Human Umbilical Cord Mesenchymal Stem Cells Improve the Status of Hypoxic/Ischemic Cerebral Palsy Rats by Downregulating NogoA/NgR/Rho Pathway.
Luo Y, Qu J, He Z, Zhang M, Zou Z, Li L, Zhang Y, Ye J
Cell transplantation 2023 Jan-Dec;32:9636897231210069
Cell transplantation 2023 Jan-Dec;32:9636897231210069
Adipose-derived stem cells with miR-150-5p inhibition laden in hydroxyapatite/tricalcium phosphate ceramic powders promote osteogenesis via regulating Notch3 and activating FAK/ERK and RhoA.
Wang F, Wang Q, Zhao Y, Tian Z, Chang S, Tong H, Liu N, Bai S, Li X, Fan J
Acta biomaterialia 2023 Jan 1;155:644-653
Acta biomaterialia 2023 Jan 1;155:644-653
Reducing GEF-H1 Expression Inhibits Renal Cyst Formation, Inflammation, and Fibrosis via RhoA Signaling in Nephronophthisis.
Hu Q, Lai J, Chen H, Cai Y, Yue Z, Lin H, Sun L
International journal of molecular sciences 2023 Feb 9;24(4)
International journal of molecular sciences 2023 Feb 9;24(4)
Silica nanoparticles suppressed the spermatogenesis via downregulation of miR-450b-3p by targeting Layilin in spermatocyte of mouse.
Zhou G, Wang J, Ren L, Liu J, Li X, Zhang Y, Sang Y, Gao L, Li Y, Sun Z, Zhou X
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
Environmental pollution (Barking, Essex : 1987) 2023 Feb 1;318:120864
Cell-in-Cell-Mediated Entosis Reveals a Progressive Mechanism in Pancreatic Cancer.
Song J, Xu R, Zhang H, Xue X, Ruze R, Chen Y, Yin X, Wang C, Zhao Y
Gastroenterology 2023 Dec;165(6):1505-1521.e20
Gastroenterology 2023 Dec;165(6):1505-1521.e20
Nose-to-brain translocation and nervous system injury in response to indium tin oxide nanoparticles of long-term low-dose exposures.
Pang Y, Qu J, Zhang H, Cao Y, Ma X, Wang S, Wang J, Wu J, Zhang T
The Science of the total environment 2023 Dec 20;905:167314
The Science of the total environment 2023 Dec 20;905:167314
Biodegradable nano black phosphorus based SDF1-α delivery system ameliorates Erectile Dysfunction in a cavernous nerve injury rat model by recruiting endogenous stem/progenitor cells.
Fu Q, Song L, Li J, Yi B, Huang Y, Zhang Z, Xin Z, Zhu J
Journal of nanobiotechnology 2023 Dec 18;21(1):487
Journal of nanobiotechnology 2023 Dec 18;21(1):487
Growth differentiation factor 5 inhibits lipopolysaccharide-mediated pyroptosis of nucleus pulposus mesenchymal stem cells via RhoA signaling pathway.
Zhu C, Zhou Q, Wang Z, Zhang J, Xu C, Ruan D
Molecular biology reports 2023 Aug;50(8):6337-6347
Molecular biology reports 2023 Aug;50(8):6337-6347
Diosmetin alleviates acute lung injury caused by lipopolysaccharide by targeting barrier function.
Xia J, Li J, Deng M, Yin F, Liu J, Wang J
Inflammopharmacology 2023 Aug;31(4):2037-2047
Inflammopharmacology 2023 Aug;31(4):2037-2047
The Inhibitory Effect of RADKPS on Pyroptosis of Nucleus Pulposus-Derived Mesenchymal Stem Cells.
Zhu C, Zhou Q, Tang L, Xuan A, Xu C, Wang Z, Ruan D
Tissue engineering. Part A 2023 Aug;29(15-16):424-438
Tissue engineering. Part A 2023 Aug;29(15-16):424-438
Rosmarinic acid alleviates intestinal inflammatory damage and inhibits endoplasmic reticulum stress and smooth muscle contraction abnormalities in intestinal tissues by regulating gut microbiota.
Li K, Wu J, Xu S, Li X, Zhang Y, Gao XJ
Microbiology spectrum 2023 Aug 18;11(5):e0191423
Microbiology spectrum 2023 Aug 18;11(5):e0191423
Inhibition of Cxcr4 Disrupts Mouse Embryonic Palatal Mesenchymal Cell Migration and Induces Cleft Palate Occurrence.
Zheng X, Zhao X, Wang Y, Chen J, Wang X, Peng X, Ma L, Du J
International journal of molecular sciences 2023 Aug 13;24(16)
International journal of molecular sciences 2023 Aug 13;24(16)
Smurf1 regulates ameloblast polarization by ubiquitination-mediated degradation of RhoA.
Niu H, Bi F, Zhao W, Xu Y, Han Q, Guo W, Chen Y
Cell proliferation 2023 Apr;56(4):e13387
Cell proliferation 2023 Apr;56(4):e13387
Tetrandrine Attenuates Podocyte Injury by Inhibiting TRPC6-Mediated RhoA/ROCK1 Pathway.
Mao L, Ding Y, Yu D, Yin J, Yu J
Analytical cellular pathology (Amsterdam) 2022;2022:7534181
Analytical cellular pathology (Amsterdam) 2022;2022:7534181
Targeting Ferroptosis Attenuates Inflammation, Fibrosis, and Mast Cell Activation in Chronic Prostatitis.
Lin D, Zhang M, Luo C, Wei P, Cui K, Chen Z
Journal of immunology research 2022;2022:6833867
Journal of immunology research 2022;2022:6833867
Overexpression of PTPRZ1 Regulates p120/β-Catenin Phosphorylation to Promote Carcinogenesis of Oral Submucous Fibrosis.
Ma L, Shen T, Peng H, Wu J, Wang W, Gao X
Journal of oncology 2022;2022:2352360
Journal of oncology 2022;2022:2352360
Tissue Kallikrein Protects Rat Prostate against the Inflammatory Damage in a Chronic Autoimmune Prostatitis Model via Restoring Endothelial Function in a Bradykinin Receptor B2-Dependent Way.
Zhang M, Lin D, Luo C, Wei P, Cui K, Chen Z
Oxidative medicine and cellular longevity 2022;2022:1247806
Oxidative medicine and cellular longevity 2022;2022:1247806
The role of activated androgen receptor in cofilin phospho-regulation depends on the molecular subtype of TNBC cell line and actin assembly dynamics.
Tahtamouni L, Alzghoul A, Alderfer S, Sun J, Ahram M, Prasad A, Bamburg J
PloS one 2022;17(12):e0279746
PloS one 2022;17(12):e0279746
Effects of Shenkang Pills on Early-Stage Diabetic Nephropathy in db/db Mice via Inhibiting AURKB/RacGAP1/RhoA Signaling Pathway.
Wang F, Fan J, Pei T, He Z, Zhang J, Ju L, Han Z, Wang M, Xiao W
Frontiers in pharmacology 2022;13:781806
Frontiers in pharmacology 2022;13:781806
Cellular mechanism of action of forsythiaside for the treatment of diabetic kidney disease.
Xu C, Miao H, Chen X, Zhang H
Frontiers in pharmacology 2022;13:1096536
Frontiers in pharmacology 2022;13:1096536
Signaling Proteins Recruited to the Sperm Binding Site: Role of β-Catenin and Rho A.
Wang H, Kinsey WH
Frontiers in cell and developmental biology 2022;10:886664
Frontiers in cell and developmental biology 2022;10:886664
eIF3a Regulates Colorectal Cancer Metastasis via Translational Activation of RhoA and Cdc42.
Mei C, Liu C, Gao Y, Dai WT, Zhang W, Li X, Liu ZQ
Frontiers in cell and developmental biology 2022;10:794329
Frontiers in cell and developmental biology 2022;10:794329
Compromised glycolysis contributes to foot process fusion of podocytes in diabetic kidney disease: Role of ornithine catabolism.
Luo Q, Liang W, Zhang Z, Zhu Z, Chen Z, Hu J, Yang K, Chi Q, Ding G
Metabolism: clinical and experimental 2022 Sep;134:155245
Metabolism: clinical and experimental 2022 Sep;134:155245
Study of differential proteomics in granulosa cells of premature ovarian insufficiency (POI) and the roles and mechanism of RAC1 in granulosa cells.
Zhang QY, Li X, Zhou XY, Li Y, Zhang J, Zhang XF, Liu YD, Chen YX, Wu XM, Ma LZ, Chen X, Chen SL
Molecular and cellular endocrinology 2022 Sep 15;555:111719
Molecular and cellular endocrinology 2022 Sep 15;555:111719
Laminin-511 Activates the Human Induced Pluripotent Stem Cell Survival via α6β1 Integrin-Fyn-RhoA-ROCK Signaling.
Nakashima Y, Tsukahara M
Stem cells and development 2022 Nov;31(21-22):706-719
Stem cells and development 2022 Nov;31(21-22):706-719
CHIR99021 balance TGFβ1 induced human corneal endothelial-to-mesenchymal transition to favor corneal endothelial cell proliferation.
Wang Y, Jin C, Tian H, Xu J, Chen J, Hu S, Li Q, Lu L, Ou Q, Xu GT, Cui H
Experimental eye research 2022 Jun;219:108939
Experimental eye research 2022 Jun;219:108939
Damnacanthal isolated from morinda species inhibited ovarian cancer cell proliferation and migration through activating autophagy.
Li R, Li H, Lan J, Yang D, Lin X, Xu H, Han B, Yang M, Su B, Liu F, Jiang W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154084
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Jun;100:154084
Circadian nuclear receptor Rev-erbα is expressed by platelets and potentiates platelet activation and thrombus formation.
Shi J, Tong R, Zhou M, Gao Y, Zhao Y, Chen Y, Liu W, Li G, Lu D, Meng G, Hu L, Yuan A, Lu X, Pu J
European heart journal 2022 Jun 21;43(24):2317-2334
European heart journal 2022 Jun 21;43(24):2317-2334
Non-canonical Wnt/calcium signaling is protective against podocyte injury and glomerulosclerosis.
Zhou D, Wang Y, Gui Y, Fu H, Zhou S, Wang Y, Bastacky SI, Stolz DB, Liu Y
Kidney international 2022 Jul;102(1):96-107
Kidney international 2022 Jul;102(1):96-107
Acetyl-L-carnitine improves erectile function in bilateral cavernous nerve injury rats via promoting cavernous nerve regeneration.
Wang J, Song J, Song G, Feng Y, Pan J, Yang X, Xin Z, Hu P, Sun T, Liu K, Xu W, Wang T, Wang S, Liu J, Ruan Y
Andrology 2022 Jul;10(5):984-996
Andrology 2022 Jul;10(5):984-996
Glycomics reveal that ST6GAL1-mediated sialylation regulates uterine lumen closure during implantation.
Han K, Wang F, Yue Y, Tan X, Tian M, Miao Y, Zhao S, Dong W, Yu M
Cell proliferation 2022 Jan;55(1):e13169
Cell proliferation 2022 Jan;55(1):e13169
The keratin 17/YAP/IL6 axis contributes to E-cadherin loss and aggressiveness of diffuse gastric cancer.
Li M, Rao X, Cui Y, Zhang L, Li X, Wang B, Zheng Y, Teng L, Zhou T, Zhuo W
Oncogene 2022 Feb;41(6):770-781
Oncogene 2022 Feb;41(6):770-781
Uncaria Rhynchophylla attenuates angiotensin Ⅱ-induced myocardial fibrosis via suppression of the RhoA/ROCK1 pathway.
Xie L, Wang T, Lin S, Lu Z, Wang Y, Shen Z, Cheng Y, Shen A, Peng J, Chu J
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112607
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Feb;146:112607
Klotho functionalization on vascular graft for improved patency and endothelialization.
Zhao P, Fang Q, Gao D, Wang Q, Cheng Y, Ao Q, Wang X, Tian X, Zhang Y, Tong H, Yan N, Hu X, Fan J
Biomaterials advances 2022 Feb;133:112630
Biomaterials advances 2022 Feb;133:112630
Berberine Depresses Inflammation and Adjusts Smooth Muscle to Ameliorate Ulcerative Colitis of Cats by Regulating Gut Microbiota.
Li X, Xu S, Zhang Y, Li K, Gao XJ, Guo MY
Microbiology spectrum 2022 Dec 21;10(6):e0320722
Microbiology spectrum 2022 Dec 21;10(6):e0320722
Construction of a novel model based on cell-in-cell-related genes and validation of KRT7 as a biomarker for predicting survival and immune microenvironment in pancreatic cancer.
Song J, Ruze R, Chen Y, Xu R, Yin X, Wang C, Xu Q, Zhao Y
BMC cancer 2022 Aug 16;22(1):894
BMC cancer 2022 Aug 16;22(1):894
Dematin inhibits glioblastoma malignancy through RhoA-mediated CDKs downregulation and cytoskeleton remodeling.
Wang M, Chen B, Zhang W, Zhang F, Qiu Y, Lin Y, Yang S
Experimental cell research 2022 Aug 1;417(1):113196
Experimental cell research 2022 Aug 1;417(1):113196
Echinococcus multilocularis drives the polarization of macrophages by regulating the RhoA-MAPK signaling pathway and thus affects liver fibrosis.
Chong S, Chen G, Dang Z, Niu F, Zhang L, Ma H, Zhao Y
Bioengineered 2022 Apr;13(4):8747-8758
Bioengineered 2022 Apr;13(4):8747-8758
Src-IL-18 signaling regulates the secretion of atrial natriuretic factor in hypoxic beating rat atria.
Li X, Wei CX, Wu CZ, Hong L, Han ZN, Liu Y, Yue-Ying W, Cui X
Kardiologia polska 2021;79(9):972-979
Kardiologia polska 2021;79(9):972-979
Human Tissue Kallikrein 1 Is Downregulated in Elderly Human Prostates and Possesses Potential In Vitro Antioxidative and Antifibrotic Effects in Rodent Prostates.
Zhang M, Luo C, Lin D, Cui K, Chen Z, Liu J
Oxidative medicine and cellular longevity 2021;2021:8877540
Oxidative medicine and cellular longevity 2021;2021:8877540
The association of transcription factor Prox1 with the proliferation, migration, and invasion of lung cancer.
Hao X, Luo W, Qiu X
Open life sciences 2021;16(1):602-610
Open life sciences 2021;16(1):602-610
PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease.
Zhang Z, Liang W, Luo Q, Hu H, Yang K, Hu J, Chen Z, Zhu J, Feng J, Zhu Z, Chi Q, Ding G
Frontiers in endocrinology 2021;12:797025
Frontiers in endocrinology 2021;12:797025
The near-infrared dye IR-61 restores erectile function in a streptozotocin-induced diabetes model via mitochondrial protection.
Yue XF, Shen CX, Wang JW, Dai LY, Fang Q, Long L, Zhi Y, Li XR, Wang YW, Shen GF, Liu ZJ, Shi CM, Li WB
Asian journal of andrology 2021 May-Jun;23(3):249-258
Asian journal of andrology 2021 May-Jun;23(3):249-258
Regulation of hepatic stellate cell contraction and cirrhotic portal hypertension by Wnt/β-catenin signalling via interaction with Gli1.
Zhang F, Wang F, He J, Lian N, Wang Z, Shao J, Ding H, Tan S, Chen A, Zhang Z, Wang S, Zheng S
British journal of pharmacology 2021 Jun;178(11):2246-2265
British journal of pharmacology 2021 Jun;178(11):2246-2265
TROAP regulates cell cycle and promotes tumor progression through Wnt/β-Catenin signaling pathway in glioma cells.
Zhao ZQ, Wu XJ, Cheng YH, Zhou YF, Ma XM, Zhang J, Heng XY, Feng F
CNS neuroscience & therapeutics 2021 Jun 2;27(9):1064-76
CNS neuroscience & therapeutics 2021 Jun 2;27(9):1064-76
Antitumor effects of dioscin in A431 cells via adjusting ATM/p53-mediated cell apoptosis, DNA damage and migration.
Wang P, Wang C, Liu C
Oncology letters 2021 Jan;21(1):59
Oncology letters 2021 Jan;21(1):59
Circ-NOLC1 promotes epithelial ovarian cancer tumorigenesis and progression by binding ESRP1 and modulating CDK1 and RhoA expression.
Chen S, Wu W, Li QH, Xie BM, Shen F, Du YP, Zong ZH, Wang LL, Wei XQ, Zhao Y
Cell death discovery 2021 Jan 22;7(1):22
Cell death discovery 2021 Jan 22;7(1):22
CircARHGAP12 promotes nasopharyngeal carcinoma migration and invasion via ezrin-mediated cytoskeletal remodeling.
Fan C, Qu H, Xiong F, Tang Y, Tang T, Zhang L, Mo Y, Li X, Guo C, Zhang S, Gong Z, Li Z, Xiang B, Deng H, Zhou M, Liao Q, Zhou Y, Li X, Li Y, Li G, Wang F, Zeng Z
Cancer letters 2021 Jan 1;496:41-56
Cancer letters 2021 Jan 1;496:41-56
m(6)A mRNA methylation regulates testosterone synthesis through modulating autophagy in Leydig cells.
Chen Y, Wang J, Xu D, Xiang Z, Ding J, Yang X, Li D, Han X
Autophagy 2021 Feb;17(2):457-475
Autophagy 2021 Feb;17(2):457-475
Therapeutic Hypothermia Mitigates the Sepsis-Increased Permeability in EA. hy926 Cells by Preserving Rap1 Expression.
Shen Y, Ding W
Therapeutic hypothermia and temperature management 2021 Dec;11(4):201-207
Therapeutic hypothermia and temperature management 2021 Dec;11(4):201-207
miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling.
Peng J, Shi S, Yu J, Liu J, Wei H, Song H, Wang S, Li Z, He S, Li L, Zhang H, Yan Z, Zhao R, Liu Y, Liu Y, Li J, Zhang R, Wang W
Cancer cell international 2021 Dec 22;21(1):702
Cancer cell international 2021 Dec 22;21(1):702
Hsa_circ_001659 serves as a novel diagnostic and prognostic biomarker for colorectal cancer.
He B, Chao W, Huang Z, Zeng J, Yang J, Luo D, Huang S, Pan H, Hao Y
Biochemical and biophysical research communications 2021 Apr 30;551:100-106
Biochemical and biophysical research communications 2021 Apr 30;551:100-106
Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway.
Dong Y, Hong W, Tang Z, Gao Y, Wu X, Liu H
Mediators of inflammation 2020;2020:5458061
Mediators of inflammation 2020;2020:5458061
Icariin Alleviates Glucocorticoid-Induced Osteoporosis through EphB4/Ephrin-B2 Axis.
Huang M, Wang Y, Peng R
Evidence-based complementary and alternative medicine : eCAM 2020;2020:2982480
Evidence-based complementary and alternative medicine : eCAM 2020;2020:2982480
Tetrandrine Suppresses Transient Receptor Potential Cation Channel Protein 6 Overexpression- Induced Podocyte Damage via Blockage of RhoA/ROCK1 Signaling.
Yu J, Zhu C, Yin J, Yu D, Wan F, Tang X, Jiang X
Drug design, development and therapy 2020;14:361-370
Drug design, development and therapy 2020;14:361-370
Tanshinone IIA Promotes Axonal Regeneration in Rats with Focal Cerebral Ischemia Through the Inhibition of Nogo-A/NgR1/RhoA/ROCKII/MLC Signaling.
Wang J, Ni G, Liu Y, Han Y, Jia L, Wang Y
Drug design, development and therapy 2020;14:2775-2787
Drug design, development and therapy 2020;14:2775-2787
TMED3 Promotes Proliferation and Migration in Breast Cancer Cells by Activating Wnt/β-Catenin Signaling.
Zhang X, Luo Y, Li Q
OncoTargets and therapy 2020;13:5819-5830
OncoTargets and therapy 2020;13:5819-5830
Liraglutide Ameliorates Erectile Dysfunction via Regulating Oxidative Stress, the RhoA/ROCK Pathway and Autophagy in Diabetes Mellitus.
Yuan P, Ma D, Gao X, Wang J, Li R, Liu Z, Wang T, Wang S, Liu J, Liu X
Frontiers in pharmacology 2020;11:1257
Frontiers in pharmacology 2020;11:1257
CEACAM6 promotes cisplatin resistance in lung adenocarcinoma and is regulated by microRNA-146a and microRNA-26a.
Du H, Li Y, Sun R, Yuan Y, Sun S, Zhang Y
Thoracic cancer 2020 Sep;11(9):2473-2482
Thoracic cancer 2020 Sep;11(9):2473-2482
The Role of ROCK in Platelet-Monocyte Collaborative Induction of Thromboinflammation during Acute Coronary Syndrome.
Hsu LW, Chen PW, Chang WT, Lee WH, Liu PY
Thrombosis and haemostasis 2020 Oct;120(10):1417-1431
Thrombosis and haemostasis 2020 Oct;120(10):1417-1431
Chronic inflammation promotes proliferation in the prostatic stroma in rats with experimental autoimmune prostatitis: study for a novel method of inducing benign prostatic hyperplasia in a rat model.
Zhang M, Luo C, Cui K, Xiong T, Chen Z
World journal of urology 2020 Nov;38(11):2933-2943
World journal of urology 2020 Nov;38(11):2933-2943
JTE-013 supplementation improves erectile dysfunction in rats with streptozotocin-induced type Ⅰ diabetes through the inhibition of the rho-kinase pathway, fibrosis, and apoptosis.
Liu K, Cui K, Feng H, Li R, Lin H, Chen Y, Zhang Y, Chen Z, Yuan H, Li M, Wang T, Lan R, Liu J, Rao K, Wen B
Andrology 2020 Mar;8(2):497-508
Andrology 2020 Mar;8(2):497-508
LncRNA CTC-497E21.4 promotes the progression of gastric cancer via modulating miR-22/NET1 axis through RhoA signaling pathway.
Zong W, Feng W, Jiang Y, Cao Y, Ke Y, Shi X, Ju S, Cong H, Wang X, Cui M, Jing R
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Mar;23(2):228-240
Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2020 Mar;23(2):228-240
Proto-Oncogene Serine/Threonine Kinase PIM3 Promotes Cell Migration via Modulating Rho GTPase Signaling.
Dang Y, Jiang N, Wang H, Chen X, Gao Y, Zhang X, Qin G, Li Y, Chen R
Journal of proteome research 2020 Mar 6;19(3):1298-1309
Journal of proteome research 2020 Mar 6;19(3):1298-1309
Impact of RhoA overexpression on clinical outcomes in cervical squamous cell carcinoma treated with concurrent chemoradiotherapy.
Tanaka K, Matsumoto Y, Ishikawa H, Fukumitsu N, Numajiri H, Murofushi K, Oshiro Y, Okumura T, Satoh T, Sakurai H
Journal of radiation research 2020 Mar 23;61(2):221-230
Journal of radiation research 2020 Mar 23;61(2):221-230
A mosquito salivary protein promotes flavivirus transmission by activation of autophagy.
Sun P, Nie K, Zhu Y, Liu Y, Wu P, Liu Z, Du S, Fan H, Chen CH, Zhang R, Wang P, Cheng G
Nature communications 2020 Jan 14;11(1):260
Nature communications 2020 Jan 14;11(1):260
Effects of mevalonate kinase interference on cell differentiation, apoptosis, prenylation and geranylgeranylation of human keratinocytes are attenuated by farnesyl pyrophosphate or geranylgeranyl pyrophosphate.
Li M, Min W, Wang J, Wang L, Li Y, Zhou N, Yang Z, Qian Q
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
Experimental and therapeutic medicine 2020 Apr;19(4):2861-2870
A DAAM1 3'-UTR SNP mutation regulates breast cancer metastasis through affecting miR-208a-5p-DAAM1-RhoA axis.
Mei J, Yan T, Huang Y, Xia T, Chang F, Shen S, Hao L, Chen Y, Wang Z, Jiang X, Xu B, Zhu Y
Cancer cell international 2019;19:55
Cancer cell international 2019;19:55
Effects of Dexmedetomidine on the RhoA /ROCK/ Nox4 Signaling Pathway in Renal Fibrosis of Diabetic Rats.
Jihua C, Cai C, Xubin B, Yue Y
Open medicine (Warsaw, Poland) 2019;14:890-898
Open medicine (Warsaw, Poland) 2019;14:890-898
Wnt5a induces ROR1 and ROR2 to activate RhoA in esophageal squamous cell carcinoma cells.
Wu X, Yan T, Hao L, Zhu Y
Cancer management and research 2019;11:2803-2815
Cancer management and research 2019;11:2803-2815
P2Y12 receptor mediates microglial activation via RhoA/ROCK pathway in the trigeminal nucleus caudalis in a mouse model of chronic migraine.
Jing F, Zhang Y, Long T, He W, Qin G, Zhang D, Chen L, Zhou J
Journal of neuroinflammation 2019 Nov 13;16(1):217
Journal of neuroinflammation 2019 Nov 13;16(1):217
lncRNA 430945 promotes the proliferation and migration of vascular smooth muscle cells via the ROR2/RhoA signaling pathway in atherosclerosis.
Cui C, Wang X, Shang XM, Li L, Ma Y, Zhao GY, Song YX, Geng XB, Zhao BQ, Tian MR, Wang HL
Molecular medicine reports 2019 Jun;19(6):4663-4672
Molecular medicine reports 2019 Jun;19(6):4663-4672
Agenesis and Hypomyelination of Corpus Callosum in Mice Lacking Nsun5, an RNA Methyltransferase.
Yuan Z, Chen P, Zhang T, Shen B, Chen L
Cells 2019 Jun 6;8(6)
Cells 2019 Jun 6;8(6)
RAB35 depletion affects spindle formation and actin-based spindle migration in mouse oocyte meiosis.
Zhang Y, Wan X, Wang HH, Pan MH, Pan ZN, Sun SC
Molecular human reproduction 2019 Jul 1;25(7):359-372
Molecular human reproduction 2019 Jul 1;25(7):359-372
Overexpression of Na(+)/H(+) exchanger 1 specifically induces cell death in human iPS cells via sustained activation of the Rho kinase ROCK.
Wakabayashi S, Morihara H, Yokoe S, Nakagawa T, Moriwaki K, Tomoda K, Asahi M
The Journal of biological chemistry 2019 Dec 20;294(51):19577-19588
The Journal of biological chemistry 2019 Dec 20;294(51):19577-19588
Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia.
Liu P, Zhang HM, Hu K, Zhou XF, Tang S
Journal of cellular physiology 2019 Aug;234(8):13534-13543
Journal of cellular physiology 2019 Aug;234(8):13534-13543
Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex.
Chen P, Zhang T, Yuan Z, Shen B, Chen L
Molecular brain 2019 Aug 28;12(1):74
Molecular brain 2019 Aug 28;12(1):74
High Expression of lncRNA AFAP1-AS1 Promotes the Progression of Colon Cancer and Predicts Poor Prognosis.
Bo H, Fan L, Li J, Liu Z, Zhang S, Shi L, Guo C, Li X, Liao Q, Zhang W, Zhou M, Xiang B, Li X, Li G, Xiong W, Zeng Z, Xiong F, Gong Z
Journal of Cancer 2018;9(24):4677-4683
Journal of Cancer 2018;9(24):4677-4683
LncRNA PCGEM1 Induces Ovarian Carcinoma Tumorigenesis and Progression Through RhoA Pathway.
Chen S, Wang LL, Sun KX, Liu Y, Guan X, Zong ZH, Zhao Y
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;47(4):1578-1588
Biocompatible PEGylated Gold nanorods function As cytokinesis inhibitors to suppress angiogenesis.
Song H, Guo T, Zhao Z, Wei Y, Luo H, Weng W, Zhang R, Zhong M, Chen C, Su J, Shen W
Biomaterials 2018 Sep;178:23-35
Biomaterials 2018 Sep;178:23-35
Long noncoding RNA AFAP1-AS1 acts as a competing endogenous RNA of miR-423-5p to facilitate nasopharyngeal carcinoma metastasis through regulating the Rho/Rac pathway.
Lian Y, Xiong F, Yang L, Bo H, Gong Z, Wang Y, Wei F, Tang Y, Li X, Liao Q, Wang H, Zhou M, Xiang B, Wu X, Li Y, Li X, Chen X, Li G, Guo C, Zeng Z, Xiong W
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):253
Journal of experimental & clinical cancer research : CR 2018 Oct 16;37(1):253
Integrin αvβ3-associated DAAM1 is essential for collagen-induced invadopodia extension and cell haptotaxis in breast cancer cells.
Yan T, Zhang A, Shi F, Chang F, Mei J, Liu Y, Zhu Y
The Journal of biological chemistry 2018 Jun 29;293(26):10172-10185
The Journal of biological chemistry 2018 Jun 29;293(26):10172-10185
Androgen deficiency impairs erectile function in rats through promotion of corporal fibrosis.
Cui K, Li R, Chen R, Li M, Wang T, Yang J, Chen Z, Wang S, Liu J, Rao K
Andrologia 2018 Feb;50(1)
Andrologia 2018 Feb;50(1)
Loss of SPRR3 in ApoE-/- mice leads to atheroma vulnerability through Akt dependent and independent effects in VSMCs.
Lietman CD, Segedy AK, Li B, Fazio S, Atkinson JB, Linton MF, Young PP
PloS one 2017;12(9):e0184620
PloS one 2017;12(9):e0184620
Exosomes Derived from Mesenchymal Stromal Cells Promote Axonal Growth of Cortical Neurons.
Zhang Y, Chopp M, Liu XS, Katakowski M, Wang X, Tian X, Wu D, Zhang ZG
Molecular neurobiology 2017 May;54(4):2659-2673
Molecular neurobiology 2017 May;54(4):2659-2673
FTY720 Supplementation Partially Improves Erectile Dysfunction in Rats With Streptozotocin-Induced Type 1 Diabetes Through Inhibition of Endothelial Dysfunction and Corporal Fibrosis.
Cui K, Ruan Y, Wang T, Rao K, Chen Z, Wang S, Liu J
The journal of sexual medicine 2017 Mar;14(3):323-335
The journal of sexual medicine 2017 Mar;14(3):323-335
Inhibition of KLF5-Myo9b-RhoA Pathway-Mediated Podosome Formation in Macrophages Ameliorates Abdominal Aortic Aneurysm.
Ma D, Zheng B, Suzuki T, Zhang R, Jiang C, Bai D, Yin W, Yang Z, Zhang X, Hou L, Zhan H, Wen JK
Circulation research 2017 Mar 3;120(5):799-815
Circulation research 2017 Mar 3;120(5):799-815
Graphene Oxide Induced Perturbation to Plasma Membrane and Cytoskeletal Meshwork Sensitize Cancer Cells to Chemotherapeutic Agents.
Zhu J, Xu M, Gao M, Zhang Z, Xu Y, Xia T, Liu S
ACS nano 2017 Mar 28;11(3):2637-2651
ACS nano 2017 Mar 28;11(3):2637-2651
Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module.
Liang D, Wang Z, Yan Z, Hou S, Xu W, Wang L, Shang M, Qiao Z
Scientific reports 2017 Mar 2;7:43798
Scientific reports 2017 Mar 2;7:43798
Reduced corporal fibrosis to protect erectile function by inhibiting the Rho-kinase/LIM-kinase/cofilin pathway in the aged transgenic rat harboring human tissue kallikrein 1.
Cui K, Luan Y, Wang T, Zhuan L, Rao K, Wang SG, Ye ZQ, Liu JH, Wang DW
Asian journal of andrology 2017 Jan-Feb;19(1):67-72
Asian journal of andrology 2017 Jan-Feb;19(1):67-72
MicroRNA-490 inhibits tumorigenesis and progression in breast cancer.
Zhao L, Zheng XY
OncoTargets and therapy 2016;9:4505-16
OncoTargets and therapy 2016;9:4505-16
The role of RhoA in vulvar squamous cell carcinoma: a carcinogenesis, progression, and target therapy marker.
Wang J, Wu Q, Zhang LH, Zhao YX, Wu X
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2879-90
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Mar;37(3):2879-90
AFAP1-AS1, a long noncoding RNA upregulated in lung cancer and promotes invasion and metastasis.
Zeng Z, Bo H, Gong Z, Lian Y, Li X, Li X, Zhang W, Deng H, Zhou M, Peng S, Li G, Xiong W
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):729-37
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 Jan;37(1):729-37
Oligophrenin1 protects mice against myocardial ischemia and reperfusion injury by modulating inflammation and myocardial apoptosis.
Niermann C, Gorressen S, Klier M, Gowert NS, Billuart P, Kelm M, Merx MW, Elvers M
Cellular signalling 2016 Aug;28(8):967-78
Cellular signalling 2016 Aug;28(8):967-78
Neurotrophic and neuroprotective properties of exendin-4 in adult rat dorsal root ganglion neurons: involvement of insulin and RhoA.
Tsukamoto M, Niimi N, Sango K, Takaku S, Kanazawa Y, Utsunomiya K
Histochemistry and cell biology 2015 Sep;144(3):249-59
Histochemistry and cell biology 2015 Sep;144(3):249-59
Inhibiting Rho kinase 2 reduces memory dysfunction in adult rats exposed to sevoflurane at postnatal days 7-9.
Han T, Hu Z, Tang Y, Shrestha A, Ouyang W, Liao Q
Biomedical reports 2015 May;3(3):361-364
Biomedical reports 2015 May;3(3):361-364
miR-125a-3p and miR-483-5p promote adipogenesis via suppressing the RhoA/ROCK1/ERK1/2 pathway in multiple symmetric lipomatosis.
Chen K, He H, Xie Y, Zhao L, Zhao S, Wan X, Yang W, Mo Z
Scientific reports 2015 Jul 7;5:11909
Scientific reports 2015 Jul 7;5:11909
Upregulated long non-coding RNA AFAP1-AS1 expression is associated with progression and poor prognosis of nasopharyngeal carcinoma.
Bo H, Gong Z, Zhang W, Li X, Zeng Y, Liao Q, Chen P, Shi L, Lian Y, Jing Y, Tang K, Li Z, Zhou Y, Zhou M, Xiang B, Li X, Yang J, Xiong W, Li G, Zeng Z
Oncotarget 2015 Aug 21;6(24):20404-18
Oncotarget 2015 Aug 21;6(24):20404-18
DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway.
Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, Liu W, Wang L, Jia W, Chen J, Ren C
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Medical oncology (Northwood, London, England) 2015 Apr;32(4):115
Overexpression of RNF146 in non-small cell lung cancer enhances proliferation and invasion of tumors through the Wnt/β-catenin signaling pathway.
Gao Y, Song C, Hui L, Li CY, Wang J, Tian Y, Han X, Chen Y, Tian DL, Qiu X, Wang E
PloS one 2014;9(1):e85377
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Baculovirus induces host cell aggregation via a Rho/Rok-dependent mechanism.
Deng Z, Huang Z, Yuan M, Yang K, Pang Y
The Journal of general virology 2014 Oct;95(Pt 10):2310-2320
The Journal of general virology 2014 Oct;95(Pt 10):2310-2320
Synergistic effect of arginine-specific ADP-ribosyltransferase 1 and poly(ADP-ribose) polymerase-1 on apoptosis induced by cisplatin in CT26 cells.
Kuang J, Wang YL, Xiao M, Tang Y, Chen WW, Song GL, Yang X, Li M
Oncology reports 2014 May;31(5):2335-43
Oncology reports 2014 May;31(5):2335-43
iTRAQ-based proteomic analysis of dioscin on human HCT-116 colon cancer cells.
Chen H, Xu L, Yin L, Xu Y, Han X, Qi Y, Zhao Y, Liu K, Peng J
Proteomics 2014 Jan;14(1):51-73
Proteomics 2014 Jan;14(1):51-73
Energy metabolism analysis reveals the mechanism of inhibition of breast cancer cell metastasis by PEG-modified graphene oxide nanosheets.
Zhou T, Zhang B, Wei P, Du Y, Zhou H, Yu M, Yan L, Zhang W, Nie G, Chen C, Tu Y, Wei T
Biomaterials 2014 Dec;35(37):9833-9843
Biomaterials 2014 Dec;35(37):9833-9843
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Kanazawa Y, Takahashi-Fujigasaki J, Ishizawa S, Takabayashi N, Ishibashi K, Matoba K, Kawanami D, Yokota T, Tajima N, Utsunomiya K
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Experimental neurology 2013 Sep;247:438-46
Loss of p57 expression and RhoA overexpression are associated with poor survival of patients with hepatocellular carcinoma.
Hu T, Guo H, Wang W, Yu S, Han L, Jiang L, Ma J, Yang C, Guo Q, Nan K
Oncology reports 2013 Oct;30(4):1707-14
Oncology reports 2013 Oct;30(4):1707-14
DEK depletion negatively regulates Rho/ROCK/MLC pathway in non-small cell lung cancer.
Wang J, Sun L, Yang M, Luo W, Gao Y, Liu Z, Qiu X, Wang E
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The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2013 Jul;61(7):510-21
Isoform-specific roles of the GTPase activating protein Nadrin in cytoskeletal reorganization of platelets.
Beck S, Fotinos A, Lang F, Gawaz M, Elvers M
Cellular signalling 2013 Jan;25(1):236-46
Cellular signalling 2013 Jan;25(1):236-46
Toosendanin induces apoptosis through suppression of JNK signaling pathway in HL-60 cells.
Ju J, Qi Z, Cai X, Cao P, Liu N, Wang S, Chen Y
Toxicology in vitro : an international journal published in association with BIBRA 2013 Feb;27(1):232-8
Toxicology in vitro : an international journal published in association with BIBRA 2013 Feb;27(1):232-8
Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling.
Liao YC, Ruan JW, Lua I, Li MH, Chen WL, Wang JR, Kao RH, Chen JH
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Oncogene 2012 Jun 21;31(25):3086-97
Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment.
D'Souza S, Kurihara N, Shiozawa Y, Joseph J, Taichman R, Galson DL, Roodman GD
Blood 2012 Feb 23;119(8):1888-96
Blood 2012 Feb 23;119(8):1888-96
Downregulation of p57 accelerates the growth and invasion of hepatocellular carcinoma.
Guo H, Lv Y, Tian T, Hu TH, Wang WJ, Sui X, Jiang L, Ruan ZP, Nan KJ
Carcinogenesis 2011 Dec;32(12):1897-904
Carcinogenesis 2011 Dec;32(12):1897-904
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 10749-1-AP(RHOA antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 10749-1-AP(RHOA antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RHOA antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RHOA. This antibody recognizes human, mouse, rat antigen. The RHOA antibody has been validated for the following applications: ELISA, WB, IHC analysis.
