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- Antibody Data
- Antigen structure
- References [7]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 13370-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13370-1-AP, RRID:AB_2271704
- Product name
- TDG antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated TDG antibody (Cat. #13370-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Nucleus-localized circSLC39A5 suppresses hepatocellular carcinoma development by binding to STAT1 to regulate TDG transcription.
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
The HOTAIRM1/miR-107/TDG axis regulates papillary thyroid cancer cell proliferation and invasion.
Thymine DNA glycosylase is a positive regulator of Wnt signaling in colorectal cancer.
Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins.
CRL4Cdt2 E3 ubiquitin ligase and proliferating cell nuclear antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase.
Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen.
Liu M, Lai M, Li D, Zhang R, Wang L, Peng W, Yang J, He W, Sheng Y, Xiao S, Nan A, Zeng X
Cancer science 2023 Oct;114(10):3884-3899
Cancer science 2023 Oct;114(10):3884-3899
TDG suppresses the migration and invasion of human colon cancer cells via the DNMT3A/TIMP2 axis.
Miao J, Zhao C, Tang K, Xiong X, Wu F, Xue W, Duan B, Zhang H, Jing X, Li W, Sun Y, Hou N, Huang C
International journal of biological sciences 2022;18(6):2527-2539
International journal of biological sciences 2022;18(6):2527-2539
The HOTAIRM1/miR-107/TDG axis regulates papillary thyroid cancer cell proliferation and invasion.
Li D, Chai L, Yu X, Song Y, Zhu X, Fan S, Jiang W, Qiao T, Tong J, Liu S, Fan L, Lv Z
Cell death & disease 2020 Apr 8;11(4):227
Cell death & disease 2020 Apr 8;11(4):227
Thymine DNA glycosylase is a positive regulator of Wnt signaling in colorectal cancer.
Xu X, Yu T, Shi J, Chen X, Zhang W, Lin T, Liu Z, Wang Y, Zeng Z, Wang C, Li M, Liu C
The Journal of biological chemistry 2014 Mar 28;289(13):8881-90
The Journal of biological chemistry 2014 Mar 28;289(13):8881-90
Oxidative stress-induced assembly of PML nuclear bodies controls sumoylation of partner proteins.
Sahin U, Ferhi O, Jeanne M, Benhenda S, Berthier C, Jollivet F, Niwa-Kawakita M, Faklaris O, Setterblad N, de Thé H, Lallemand-Breitenbach V
The Journal of cell biology 2014 Mar 17;204(6):931-45
The Journal of cell biology 2014 Mar 17;204(6):931-45
CRL4Cdt2 E3 ubiquitin ligase and proliferating cell nuclear antigen (PCNA) cooperate to degrade thymine DNA glycosylase in S phase.
Shibata E, Dar A, Dutta A
The Journal of biological chemistry 2014 Aug 15;289(33):23056-23064
The Journal of biological chemistry 2014 Aug 15;289(33):23056-23064
Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen.
Hu XV, Rodrigues TM, Tao H, Baker RK, Miraglia L, Orth AP, Lyons GE, Schultz PG, Wu X
Proceedings of the National Academy of Sciences of the United States of America 2010 Aug 24;107(34):15087-92
Proceedings of the National Academy of Sciences of the United States of America 2010 Aug 24;107(34):15087-92
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 13370-1-AP(TDG antibody) at dilution of 1:400
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The TDG antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TDG. This antibody recognizes human,mouse,rat antigen. The TDG antibody has been validated for the following applications: ELISA, WB, IP analysis.
